AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting with histone H2AX

AIF: Not Just an Apoptosis-Inducing Factor

(2009) Nicholas Joza et al.   Annals of the New York Academy of Sciences

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

(2009) YoungSik Cho et al.   CELL

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Caspase-Independent Pathways of Programmed Cell Death: The Unraveling of New Targets of Cancer Therapy?

(2009) C. Constantinou et al.   CURRENT CANCER DRUG TARGETS

Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos

(2009) Yingfei Wang et al.   EXPERIMENTAL NEUROLOGY

Redox-Linked Conformational Dynamics in Apoptosis-Inducing Factor

(2009) Irina F. Sevrioukova   JOURNAL OF MOLECULAR BIOLOGY

Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos)

(2009) Yingfei Wang et al.   JOURNAL OF NEUROCHEMISTRY

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL

The molecular archaeology of a mitochondrial death effector: AIF in Drosophila

(2008) N Joza et al.   CELL DEATH AND DIFFERENTIATION

Protein kinase C protects from DNA damage-induced necrotic cell death by inhibiting poly(ADP-ribose) polymerase-1

(2008) Csaba Hegedűs et al.   FEBS LETTERS

Death Receptor-Induced Activation of the Chk2- and Histone H2AX-Associated DNA Damage Response Pathways

(2008) S. Solier et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2AX is a critical factor for cellular protection against DNA alkylating agents

(2008) J A Meador et al.   ONCOGENE