Article
Spectroscopy
Wensong Yao, Xiaomin Zhang, Zhen Lin
Summary: The study demonstrates that sodium molybdate significantly enhances the chemiluminescent reaction between hydrogen peroxide and luminol, providing a convenient and sensitive method for hydrogen peroxide determination, as well as potential application for glucose detection when combined with glucose oxidase. This finding suggests promising applications of sodium molybdate in analytical chemistry.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Huairong Zhang, Yong Liu, Mei Yao, Wenxiu Han, Shusheng Zhang
Summary: Cathodic electrochemiluminesence (ECL) microscopy based on luminol analog L012 utilizes multiwalled carbon nanotubes (MWCNTs) as coreactant accelerators to convert oxygen and H2O2 into reactive oxygen species. The produced ROS oxidizes L012 to emit bright cathodic ECL illumination, enabling the imaging of nanotubes and nucleolin on tumor cells. By modifying MWCNTs with AS1411 aptamers, label-free ECL imaging of nucleolin on plasma membranes was achieved, providing a universal approach in single nanomaterial and single-cell imaging.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Lucia Simona Ferraraccio, Donatella Di Lisa, Laura Pastorino, Paolo Bertoncello
Summary: A simple procedure for incorporating enzymes into alginate hydrogels was reported, and electrochemiluminescence was used for detecting the enzymatic reactions. The immobilized enzymes showed maintained activity and good stability within the alginate hydrogels for up to 28 days. The sensitivity and selectivity of the encapsulated enzymes were demonstrated through testing real samples.
ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Simon Deepa, Raja Venkatesan, Suseela Jayalakshmi, Monogar Priya, Seong-Cheol Kim
Summary: This article reviews the use of chemiluminescence techniques, specifically focusing on the application of luminol for environmental, chemical, and biological analytes. Significant advances have been made in the past 20 years, improving sensitivity by considering optimal catalyst choices. Bio-based catalysts and metal nanoparticles have shown promise in enhancing sensitivity, selectivity, and stability, as well as expanding the scope of applications and providing unique insights into the reaction mechanism.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Analytical
Harley Quinn, Wenlu Wang, Joerg G. Werner, Keith A. Brown
Summary: This article introduces a high-throughput method for detecting sub-micron defects in insulating thin films using electrochemiluminescence (ECL) technology. By optimizing reagent concentrations, buffers, voltage, and excitation time, features with areas 500 times smaller than the area interrogated by a single pixel of the camera can be detected. This method is expected to have a major impact on the automated discovery of multifunctional films due to its parallelizability and scalability.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Analytical
Zhichen Zhang, Yujing Zhu, Zejing Xing, Jing Li, Qin Xu, Jun-Jie Zhu, Cheng Ma
Summary: This study developed an in situ strategy to regulate the intensity and layer thickness of electrochemiluminescence (ECL) by introducing an ultrasound probe. Ultrasonic radiation enhanced the ECL intensity under the catalytic route, while it had an opposite effect under the oxidative-reduction route. Ultrasound promoted the direct electrochemical oxidation of TPrA radicals, resulting in a thinner ECL layer. This in situ ultrasound strategy provides a new opportunity to understand ECL mechanisms and regulate ECL imaging.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Jing Ye, Liping Zhu, Mengxia Yan, Ting Xiao, Libing Fan, Yu Xue, Jianshe Huang, Xiurong Yang
Summary: This paper presents an intensive and glow-type chemiluminescence hydrogel prepared by incorporating luminol and hemin into the scaffold of guanosine-derived hydrogel. The hydrogel exhibits significant enzyme-like activity to H2O2 and can emit blue light visible to the naked eye for over 8 hours. The lasting-time CL emission is achieved through slow-diffusion-controlled heterogeneous catalysis mechanism, showing promising application in cold light source and H2O2 detection in real biological samples.
Article
Chemistry, Analytical
Xin Jie Wu, Chang Ping Yang, Zhong Wei Jiang, Si Yu Xiao, Xiao Yan Wang, Cong Yi Hu, Shu Jun Zhen, Dong Mei Wang, Cheng Zhi Huang, Yuan Fang Li
Summary: A catalyst-free co-reaction luminol-H2O2-K2S2O8 chemiluminescence (CL) system was developed, which exhibited long-life and high-intensity emission lasting for 6 hours. The mechanism of persistent and intense emission was discussed based on CL spectra, cyclic voltammetry, electron spin resonance (ESR), and the effects of radical scavengers. A CL-based method for the detection of ALP was established with good linearity and a low limit of detection. This method was successfully applied to detect ALP in human serum samples.
Article
Spectroscopy
Mortaza Iranifam, Mahtab Toolooe Gardeh Rasht, Haider A. J. Al Lawati
Summary: A new CL method utilizing CuS nanoparticles-luminol-O2 system was developed to measure PCM and VAN concentrations. Both drugs decreased CL intensity, with detection limits of 2.9 x 10(-5) mol L-1 for PCM and 8.9 x 10(-6) mol L-1 for VAN.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biochemical Research Methods
Mohamed Ibrahim Halawa, GuoXing Wu, Bing Shi Li
Summary: By synthesizing PVP-I-2@AuNPs and forming a chemiluminescent system with luminol, ultra-sensitive detection of Hg2+ ions with a detection limit of 0.1 nM was achieved. The system showed excellent selectivity and linear response, making it a promising sensor for real-time detection of Hg2+.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Jaeyoon Kim, Hanseok Yi, Daeho Jeong, Dongil Lee, Won-Yong Lee
Summary: This study investigated the electrogenerated chemiluminescence behavior of luminol on a glassy carbon electrode modified with gold nanocluster-graphene-Nafion composite films in neutral aqueous solution. The composite films showed enhanced electrocatalytic activity towards the reduction of molecular oxygen, resulting in a strong cathodic luminol ECL response. Addition of hydrogen peroxide led to a decrease in the cathodic ECL response related to oxygen reduction and a new ECL response related to the electrochemical reduction of hydrogen peroxide was observed. The ECL response was linear with the concentration of hydrogen peroxide in the range of 1.0 x 10(-8) M to 4.0 x 10(-6) M with a detection limit of 2.21 x 10(-9) M in neutral aqueous solution.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Yiran Zhao, Julie Descamps, Nour al Hoda Al Bast, Marcos Duque, Jaume Esteve, Borja Sepulveda, Gabriel Loget, Neso Sojic
Summary: A new all-optical strategy for electrochemiluminescence (ECL) is reported, which eliminates the need for an external power supply and electrical wires. The fully integrated all-optical wireless device utilizes a modified nanostructured Si photovoltaic junction to induce ECL emission under illumination. This breakthrough opens up new opportunities for developing portable sensing devices.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Shaida Mahmoudi, Mohamad Javad Chaichi, Mojtaba Shamsipur, Ome Leila Nazari, Abdolraouf Samadi-Maybodi
Summary: A Fe3O4@Zn/Mg MOF composite with high peroxidase-like activity was synthesized and utilized for measuring atropine in Datura plants. This method is characterized by its fast, reversible, and selective features.
Article
Chemistry, Analytical
Huanhuan Zhu, Yonghong Xie, Xue Zou, Tengfei Wang, Zhengjun Gong
Summary: This study discovered the enhancing effect of TCEP on the luminol-H2O2 chemiluminescence system and established a rapid, stable, and sensitive detection method using flow injection analysis. The method showed linear response to TCEP concentration with low detection limit and good recoveries, making it a promising approach for environmental pollutant detection.
Article
Chemistry, Multidisciplinary
Fuqian Chen, Ying Zhang, Ting Li, Danfeng Peng, Zhiwen Qi, Jianping Song, Tao Deng, Fang Liu
Summary: A variety of luminol derivatives with N- and O-substitution have been synthesized, showing broad functional group tolerance. O-esterification has been demonstrated as a promising method for preparing enhanced chemiluminescence (CL) reagents for detecting hemin, bloodstain, and horseradish peroxidase (HRP). The most effective analogue with a deuterated acetyl group exhibited greater potential than luminol for bloodstain and HRP imaging. Additionally, O-etherification can greatly suppress CL signal and has been applied to design a CL probe for beta-glucosidase.
CHINESE CHEMICAL LETTERS
(2023)