期刊
ELECTROCHEMISTRY COMMUNICATIONS
卷 10, 期 12, 页码 1844-1846出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2008.09.024
关键词
Chiral sensor; Enantioselective; Indium tin oxide; Field effect transistor; Protein; Asymmetric synthesis
资金
- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan
The present study aims at extending the possibility of utilizing bulky molecules such as proteins for fabricating electrochemical chiral sensors using an indium tin oxide (ITO) electrode. Enantioselective potential response of the human serum albumin (HSA)-modified ITO electrode was observed for tryptophan (Trp) when HSA was immobilized on an ITO electrode surface modified with disuccinimidyl suberate (DSS). In this sensing system. the enantioselective interaction between HSA and Trp is detected through the chemically reactive DSS group immobilized on the ITO electrode. (C) 2008 Elsevier B.V. All rights reserved.
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