期刊
ELECTROANALYSIS
卷 24, 期 6, 页码 1311-1317出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201200119
关键词
DNA sensors; Electrical impedance spectroscopy; Ferricyanide; Hydroquinone; Polypyrrole
资金
- Institute of Environmental Science and Research Ltd.
- University of Auckland
Much research-to-date exists to create sensitive and selective DNA sensors. A variety of approaches are adopted, including those involving polypyrrole and electrical impedance spectroscopy. Combined these are able to sense as well as aptly transduce signals. Many such sensors employ ferri/ferrocyanide to exhibit surface hybridization. This redox reporter, though with merits, can prove disadvantageous. To this end, a comparative study was performed with the redox reporter hydroquinone. For comparison purposes ferri/ferrocyanide indicated greater sensitivity, suggested to arise from inherent charge. Conversely, with hydroquinone steric hindrance is the main influencing factor. Such a study aims to guide design of analogous sensors.
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