Review
Biochemistry & Molecular Biology
Alexandra Virginia Bounegru, Constantin Apetrei
Summary: In recent years, researchers have focused on developing simple and efficient methods based on electrochemical biosensors to determine hydroxycinnamic acids from various real samples. Enzymatic biosensors represent a promising, low-cost technology for direct monitoring of these important compounds. Immobilization techniques are crucial for stability and obtaining accurate results, and nanomaterials have been utilized to improve enzyme immobilization and electron transport rates.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Analytical
Gabriel J. Mattos, Carlos A. R. Salamanca-Neto, Eduardo C. M. Barbosa, Pedro H. C. Camargo, Robert F. H. Dekker, Aneli M. Barbosa-Dekker, Elen R. Sartori
Summary: A photoelectrochemical biosensing strategy was developed for highly sensitive detection of the flavonoid rutin. By integrating hematite decorated with palladium nanoparticles and biocatalysis towards laccase-based reactions, a novel biosensing platform was created, showing good sensitivity, selectivity, repeatability, and storage stability.
Article
Chemistry, Analytical
Xin-Yan Song, Xin Meng, Bao-Lin Xiao, Yang-Yang Li, Xin-Xin Ma, Ali Akbar Moosavi-Movahedi, Jun Hong
Summary: In this study, a biosensor based on multi-walled carbon nanotubes and laccase nanocomposite-modified electrodes was developed for the sensitive and selective detection of rutin. The biosensor showed a wide linear range and low detection limits, and demonstrated high accuracy in detecting rutin tablets and serum samples. This biosensor has potential practical applications in rutin drug quality testing and clinical blood drug concentration monitoring.
Article
Engineering, Chemical
Xi Lin, Yuchen Zhou, Zhenfeng Lei, Rui Chen, Wanchun Chen, Xiangying Meng, Yanxia Li
Summary: In this study, a facile electrochemical biosensing platform was developed by immobilizing laccase on laser-induced graphene electrode through glutaraldehyde covalent binding for the determination of gallic acid. The prepared electrode showed excellent linear relationship with gallic acid and low detection limit under optimized experimental conditions.
Article
Electrochemistry
Sandra Jose, Ditto Abraham Thadathil, Munmun Ghosh, Anitha Varghese
Summary: The uncontrolled release of harmful endocrine disruptors (EDs) is causing serious damage to human and animal health. A biosensor called Lac/PAA/CFP, which immobilizes laccase over electropolymerized poly anthranilic acid on a carbon fiber paper (CFP) electrode, was developed for the detection of p-nonylphenol (PNP), a persistent phenolic endocrine disruptor and a harmful eco-toxic pollutant. The biosensor showed good selectivity and a low limit of detection for PNP in real water samples.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Miaoron Zhamg, Yan Zhang, Chuankai Yang, Chunyun Ma, Yuhang Zhang, Jianguo Tang
Summary: The novel colorimetric biosensor based on La-MFs fabricated via biomineralization showed enhanced detection performance for EP, with a wide linear detection range and good selectivity. The La-MFs exhibited satisfactory storage stability and reusability for EP detection.
MICROCHEMICAL JOURNAL
(2022)
Review
Chemistry, Multidisciplinary
Saptashwa Datta, R. Veena, Melvin S. Samuel, Ethiraj Selvarajan
Summary: This review article discusses the immobilization methods of laccases, nanomaterials used for immobilization, and applications for the detection and degradation of pollutants.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Article
Biochemistry & Molecular Biology
Alexandra Virginia Bounegru, Constantin Apetrei
Summary: The study introduced a novel enzymatic biosensor, utilizing a screen-printed electrode modified with carbon nanofibers to determine the content of p-coumaric acid. The biosensor showed stable and sensitive responses, with low LOD and LOQ values, and successfully detected p-coumaric acid in phytoproducts of complex composition. The results obtained were comparable to those obtained by the standard spectrometric method.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Polymer Science
Ancuta Dinu, Constantin Apetrei
Summary: This study presents the development of a new enzyme sensor for the quantification of tyrosine in pharmaceuticals. The enzyme sensor showed a low limit of detection and high sensitivity, and was validated using infrared spectrometry on pharmaceuticals from different manufacturers.
Article
Chemistry, Analytical
Sinem Evli, Deniz Aktas Uygun
Summary: One-dimensional Ni/Au/PPy-COOH nanowires with multiple segments were synthesized and their smooth surfaces and magnetic properties were investigated. These nanowires were used to modify the electrode surface and as a micro-environment for Trametes versicolor laccase. The biosensor based on this design demonstrated high sensitivity, excellent selectivity, wide linear range, and low LOD for the detection of dopamine in biological samples.
Review
Chemistry, Analytical
Sakshi Verma, Deeksha Thakur, Chandra Mouli Pandey, Devendra Kumar
Summary: Phenolic compounds (PhCs) are widely found in plants, body fluids, food items, medicines, pesticides, dyes, etc., and many of them are highly toxic, teratogenic, and carcinogenic. There is an urgent need to develop an effective tool for the analysis of PhCs to address their environmental and health concern. Carbonaceous nanomaterials have emerged as a promising material for the fabrication of electrochemical biosensors for the detection of PhCs.
Article
Chemistry, Analytical
Olha Demkiv, Galina Gayda, Nataliya Stasyuk, Olena Brahinetz, Mykhailo Gonchar, Marina Nisnevitch
Summary: This article describes the development of amperometric biosensors based on laccase and redox-active micro/nanoparticles. It was found that laccase/CuCo/GE exhibited the highest sensitivity to catechol, suggesting potential applications of these sensors for the analysis of phenolic derivatives.
Article
Polymer Science
Yasemin A. Udum, Melek Aktas Gemci, Duygu Cevher, Saniye Soylemez, Ali Cirpan, Levent Toppare
Summary: In this study, a novel D-A-D type monomer containing hexylthiophene as the donor and benzo[c][1,2,5]thiadiazole as the acceptor was successfully electropolymerized to produce P(DTFBT). The electrochromic properties of the polymer and its performance in amperometric biosensors were investigated. The modified electrode surface with laccase immobilization showed potential for catechol sensing. Biosensor optimization values, cycle number, enzyme amount, pH, and interfering compounds were also examined. The results demonstrated that the sensor had satisfactory accuracy and could be used for catechol quantification.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Chemistry, Inorganic & Nuclear
Thatchanamoorthy Thenrajan, Selvasundarsekar Sam Sankar, Girija Srinivasan, Subrata Kundu, Jeyaraj Wilson
Summary: Researchers have recently paid significant attention to monitoring pollutants, particularly water pollution, due to their impact on major diseases and long-term health problems. The sensor designed in this study showed excellent performance for real sample analysis, indicating its reliability for use in environmental monitoring, public health care, industrial areas, and waste water management systems.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Physical
Sumit Kumar, Anamika Sindhu, Pannuru Venkatesu
Summary: Inspired by the biocompatibility and dexterity of ionic liquids in preserving enzyme structure and activity, this study investigated the interactions between Cyt-c and naked AuNPs as well as four IL-mediated AuNPs. The results showed that IL-AuNPs significantly enhanced the peroxidase activity and exhibited preference in counteracting temperature gradient change and long-term solvent preservation effects. The study also revealed the dominance of IL anions in modulating the interactions between IL-mediated AuNPs and Cyt-c. These findings suggest the promising potential of sulfur-containing IL-mediated AuNPs for Cyt-c immobilization and for applications in drug delivery and therapeutics.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Biophysics
Lian-Hua Xu, Jun-ji Li, Hai-Bo Zeng, Xue-Ji Zhang, Serge Cosnier, Robert S. Marks, Dan Shan
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Chemistry, Analytical
Wen-Rong Cai, Hai-Bo Zeng, Huai-Guo Xue, Robert S. Marks, Serge Cosnier, Xue-Ji Zhang, Dan Shan
ANALYTICAL CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Shuqin Fang, Bo Liang, Xinxin Xiao, Lu Bai, Xiangjiang Tang, Elisabeth Lojou, Serge Cosnier, Aihua Liu
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Chemistry, Physical
Hani Farhat, Christine Taviot-Gueho, Guillaume Monier, Valerie Briois, Claude Forano, Christine Mousty
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Article
Chemistry, Analytical
Quentin Palomar, XingXing Xu, Chantal Gondran, Michael Holzinger, Serge Cosnier, Zhen Zhang
Article
Electrochemistry
Meenakshi Singh, Hugo Nolan, Maryam Tabrizian, Serge Cosnier, Georg S. Duesberg, Michael Holzinger
Article
Chemistry, Multidisciplinary
Marie Carriere, Paulo Henrique M. Buzzetti, Karine Gorgy, Muhammad Mumtaz, Christophe Travelet, Redouane Borsali, Serge Cosnier
Summary: A series of new glyconanoparticles were successfully obtained by self-assembly and post-functionalization, showcasing spherical morphology and nanometric size. These particles exhibit classical electroactivity and the amount of immobilized redox compound is proportional to the percentage of polystyrene-block-beta-cyclodextrin in the composition. Modulation of surface density of beta-cyclodextrin on the nanoparticles shell may lead to the preparation of different electroactive particles and those modified by biotinylated proteins.
Article
Chemistry, Analytical
Junji Li, Wen-Li Xin, Yu-Xuan Dai, Guofang Shu, Xue-Ji Zhang, Robert S. Marks, Serge Cosnier, Dan Shan
Summary: Metal-organic frameworks (MOFs) are versatile coordinators for synthesizing high-performance catalysts, such as the redox-alternating CuxO electrochemical catalyst. The study synthesized a novel precursor MOF and characterized the transformation towards a highly active nanocomposite through temperature modulation to enhance sensitivity in H2O2 reduction. The resulting sensor material exhibited amplified sensitivity and ease of preparation, suggesting wide applications in medical settings.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Junji Li, Kun-Kun Lu, Lian-Hua Xu, Yi-Xuan Li, Han Li, Guofang Shu, Xue-Ji Zhang, Robert S. Marks, Serge Cosnier, Dan Shan
Summary: Reasonable control of redox states and substrate interconnection degrees is crucial for modulating sensor performance. The optimized electrochemical H2O2 sensor with low detection limit and good linear range was successfully prepared in this study.
Article
Chemistry, Analytical
Li-Ping Zong, Junji Li, Guofang Shu, Xinye Liu, Robert S. Marks, Xue-Ji Zhang, Serge Cosnier, Dan Shan
Summary: A novel ECL amplification strategy was established by designing Fe-N-C nanosheets with exceptional catalytic activity for O-2 activation. The material was successfully applied for antibiotic detection, indicating promising prospects for biological analysis and environmental monitoring.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Paulo Henrique M. Buzzetti, Anastasiia Berezovska, Yannig Nedellec, Serge Cosnier
Summary: This article describes a new concept of a hollow electrode based on the assembly of two buckypapers, which can contain a biocatalyst in a microcavity. The experimental results show that the hollow bioelectrodes have good storage stability and electroenzymatic activity in aqueous solution.
Article
Chemistry, Physical
Ali Tarhini, Juan Aguirre-Araque, Melanie Guyot, Cyrille Costentin, Guillaume Rogez, Sylvie Chardon-Noblat, Vanessa Prevot, Christine Mousty
Summary: Organic-inorganic hybrid materials were synthesized by intercalation method and applied as modified electrodes for CO2 electroreduction reaction. The intercalated materials exhibited high selectivity for H-2 production without CO formation.
Article
Chemistry, Multidisciplinary
Li-Ping Zong, Xiaozhong Chen, Dunru Zhu, Xi-Jie Li, Feng Li, Serge Cosnier, Xue-Ji Zhang, Robert S. Marks, Dan Shan
Summary: A novel electrochemiluminescence amplification strategy was developed using macrocyclic Schiff base Fe complexes, which showed remarkable redox electrocatalytic properties and enhanced ECL efficiency. The strategy was successfully applied in the detection of neomycin, highlighting its potential in biological analysis and environmental monitoring.
Review
Chemistry, Analytical
Christine Mousty, Hani Farhat
Summary: Among the nanomaterials reported in the literature, layered double hydroxides (LDHs), especially transition metal-based LDHs, show excellent electrocatalytic properties for redox reactions with analytes. The integration of TM-LDHs with conductive materials, such as graphene or metal nanoparticles, enhances the electronic conductivity and electrocatalytic activity of LDH-based composites. This mini-review discusses the specific electrocatalytic role played by different transition metals (Ni, Co, Cu, Mn, and Fe) in LDH layers and their impact on the performance of TM-LDHs-based sensors.
Article
Nanoscience & Nanotechnology
Paulmanickam Koilraj, Masanori Takemoto, Yasuaki Tokudome, Angelique Bousquet, Vanessa Prevot, Christine Mousty
ACS APPLIED NANO MATERIALS
(2020)
