Article
Chemistry, Analytical
Tiago A. Matias, Lucas de Faria, Raquel G. Rocha, Murillo N. T. Silva, Edson Nossol, Eduardo M. Richter, Rodrigo A. A. Munoz
Summary: A laser-induced graphene (LIG) surface modified with Prussian blue (PB) was developed as a novel electrochemical sensing platform for hydrogen peroxide detection. This platform exhibited excellent sensing performance, including high stability, wide linear range, fast response, and satisfactory detection limit.
Article
Chemistry, Analytical
Lujun Wang, Martin Pumera
Summary: This study demonstrates the activation of a 3D-printed electrode prepared using FDM 3D printing technology and the preparation of a glucose oxidase-based 3D-printed nanocarbon electrode through covalent linkage method. The biosensor shows excellent stability and opens new possibilities for covalent modifications in various electrochemistry fields.
Article
Electrochemistry
Sinan Mithat Muhammet
Summary: A sensitive and selective amperometric sensor for hydrogen peroxide was developed by mixing graphene oxide and alizarin red and coating it onto a glassy carbon electrode. The activated sensor exhibited high electrocatalytic activity and reversible redox ability, with high sensitivity and selectivity for hydrogen peroxide measurement.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2022)
Article
Engineering, Chemical
Sadia Parveen, Sk Najrul Islam, Absar Ahmad
Summary: This study presents the successful biogenic synthesis of fluorescent Ruthenium oxide quantum dots (RuO2 QDs) mediated by endophytic fungus Fusarium oxysporum at room temperature, demonstrating its potential application in colorimetric detection of H2O2.
ADVANCED POWDER TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Veeramani Mangala Gowri, Ajay Ajith, S. Abraham John
Summary: Researchers have synthesized graphitic carbon nitride (GCN) from various precursors and attached it to electrode substrates after exfoliation under different conditions, leading to inconsistent data on electrochemical properties. This study systematically investigated the morphology, electrochemical impedance, and electrocatalytic activity of GCN modified on GC substrate from different exfoliation times, showing that GCN exfoliated for 120 minutes exhibited the highest electrocatalytic activity.
Article
Chemistry, Physical
Mohammad Saleh Attayeenia, Rasool Amini, Shirin Vardak
Summary: Pencil graphite electrodes modified with silver nanoparticles were used for rapid and sensitive detection of hydrogen peroxide. The sensor showed a linear response within a certain concentration range and exhibited high selectivity towards interfering substances.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Multidisciplinary
Ke-Ke Guo, Xin-Ye Jiang, Ming Xu, Feng-Yan Li, Si-Meng Dong, Yue Zheng, Lin Xu
Summary: The POM-based 1D chain compound synthesized exhibits a unique double chain structure with opposite charges. It shows a relatively high electrical conductivity compared to common POMs, and has semiconducting properties investigated through photoelectrochemical sensing of H2O2.
CHEMICAL COMMUNICATIONS
(2021)
Article
Engineering, Environmental
Taynara O. Silva, Lorena A. Goulart, Isaac Sanchez-Montes, Gessica O. S. Santos, Renato B. Santos, Renata Colombo, Marcos R. V. Lanza
Summary: This study developed and applied a gas diffusion electrode (GDE) based on PL6C/2.0%BTDA for efficient electrogeneration of H2O2 and degradation of CIP using various AOPs. The modified GDE exhibited superior performance at a current density of 25 mA cm-2, producing higher amounts of H2O2 and achieving lower energy consumption. Among the AOPs investigated, the AO/e-H2O2/UVC technique was the most efficient, completely removing CIP in 20 minutes while yielding the highest kinetic constant and lower electrical energy per order.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Khursheed Ahmad, Haekyoung Kim
Summary: In recent years, the electrochemical sensing approach has gained significant attention due to its excellent detection performance. In this study, the active surface of a screen printed carbon electrode was successfully modified using nitrogen doped reduced graphene oxide, resulting in an electrode with excellent detection performance and selectivity. The experimental results also demonstrated the outstanding performance of this electrode in the detection of hydrogen peroxide.
Article
Energy & Fuels
Norah M. BinSaeedan, Prabhakarn Arunachalam, Abdullah M. Al-Mayouf, Maged N. Shaddad, Mabrook S. Amer, Abeer M. Beagan, Francisco Fabregat-Santiago, Juan Bisquert
Summary: This study focuses on the development of cost-efficient materials for electrochemical hydrogen peroxide production, with the introduction of surface oxygen vacancies in mesoporous SnO2 electrodes proven to enhance their selectivity and performance.
INTERNATIONAL JOURNAL OF ENERGY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Patricia H. R. Martins, Adolfo I. B. Romo, Francisco O. N. da Silva, Otaciro R. Nascimento, Joaquin Rodriguez-Lopez, Izaura C. N. Diogenes, Luiz G. F. Lopes, Eduardo H. S. Sousa
Summary: The role and reactivity of metal complexes in interacting with DNA, especially metallonitrosyl compounds, have been poorly investigated. A nitrosyl compound cis-[Ru(bpy)(2)(SO3)(NO)](PF6)(A) exhibited promising biological activities, while a final product cis-[Ru(bpy)(2)(SO3)(H2O](B) showed important reactivity with H2O2 causing DNA degradation. The aqua product of the nitrosyl ruthenium complex should be further studied for its potential genotoxicity to DNA.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2023)
Review
Chemistry, Analytical
Preeyaporn Reanpang, Pijika Mool-am-kha, Jantima Upan, Jaroon Jakmunee
Summary: A simple, rapid, and cost-effective flow injection amperometric sensor was developed for sensitive determination of uric acid, utilizing a new combination of carbon black and graphene oxide modified screen-printed carbon electrode. The modified electrode showed enhanced sensitivity, stability, and automation for uric acid detection. The system achieved good selectivity, repeatability, and stability, with a detection limit of 0.01 µM and a throughput of 25 injections per hour.
Article
Chemistry, Physical
Yuling Cheng, Bin Wang, Youzhi Liu, Jing Gao, Dongming Zhang
Summary: In this study, a novel paper-based electrode with a unique three-dimensional porous structure was successfully fabricated for the electrooxidation of H2O2 in alkaline environment. The electrode exhibited high catalytic activity due to the presence of nanomaterials and the synergistic effect. Moreover, the electrode preparation process without using any organic binder ensured good conductivity and stability.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2022)
Article
Chemistry, Multidisciplinary
Hua Tian, Yunyi He, Lin Wang, Yuannan Lai, Jianwei Wang, Hanqing Xiang, Wenjun Zhao, Lin Zhang
Summary: This study demonstrates the successful pre-intercalation of caesium and sodium ions as pillars into vanadium oxide bronze nanowires, leading to the formation of a two-dimensional tunnel structure and achieving high capacity and excellent cycling stability in aqueous zinc-ion batteries.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Environmental Sciences
Setare Jalali, Mehdi Ardjmand, Bahman Ramavandi, Ferial Nosratinia
Summary: In this study, Zeolite-MgO catalyst was prepared using alkali-thermal method and applied to decrease amoxicillin concentration in wastewater. Various tests were conducted to determine the catalyst properties and optimization led to improved removal efficiency. The results identified the potential of Zeolite-MgO catalyst for wastewater treatment.
Article
Chemistry, Analytical
Fabiana F. Silva, Carla S. Santos, Gabriel N. Meloni, Alex S. Lima, Mauro Bertotti
Summary: In this study, an analytical strategy utilizing the EC' mechanism involving ascorbate and oxidized ferrocenemethanol was developed to monitor low concentrations of ascorbate. The feasibility of this approach was investigated using different mass transport regimes and both macro- and ultramicroelectrodes. An electrocatalytic process was confirmed, and a correlation between ascorbate concentration and steady-state current was established, allowing for the detection of ascorbate in the micromolar range. This method was successfully applied to quantify ascorbate in a commercial juice sample.
Article
Chemistry, Analytical
William B. Veloso, Vanessa N. Ataide, Diego P. Rocha, Helton P. Nogueira, Abner de Siervo, Lucio Angnes, Rodrigo A. A. Munoz, Thiago R. L. C. Paixao
Summary: The combination of CO2 laser ablation and electrochemical surface treatments enhances the electrochemical performance of 3D-printed CB/PLA electrodes by producing Na2O flower-like nanostructures on their surface. SEM images show that the treatment ablates the polymeric layer of the electrode, exposing a porous surface for the formation of Na2O nanostructures. The electrodes treated by this combined method exhibit improved performance and electrochemical response for tyrosine oxidation, making them suitable sensors for biological sample analysis, even at low analyte concentrations.
Review
Chemistry, Analytical
Habdias A. Silva-Neto, Iana V. S. Arantes, Andre L. Ferreira, Guida H. M. do Nascimento, Gabriel N. Meloni, William R. de Araujo, Thiago R. L. C. Paixa, Wendell K. T. Coltro
Summary: Paper-based microfluidic devices have become powerful platforms for bioanalysis due to their simpler fabrication protocols, compatibility with multi-purpose detectors, and global affordability. This review provides an overview of manufacturing methods, integrative sensing materials, the clinical relevance of biomarkers and bioanalysis, as well as examples of applications involving various samples and diseases. It also discusses the recent developments in paper-based wearable devices and hybrid sensors for clinical applications.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Electrochemistry
Juliana L. M. Gongoni, Lauro A. P. Filho, Davi M. De Farias, Iana V. S. Arantes, Thiago R. L. C. Paixao
Summary: Miniaturized paper-based electrochemical sensors were fabricated using kraft paper and CO2 laser, eliminating the need for chemical reagents and controlled conditions. The study optimized the paper type and laser processing parameters to improve the electrodes' performance. Electrochemical treatment further enhanced the sensors' electroactive area and roughness, resulting in improved selectivity and sensitivity for nitrite determination. The sensors also demonstrated good repeatability and batch-to-batch reproducibility. This work presents a sustainable approach to fabricating competitive electrochemical sensors and provides possibilities for designing new analytical systems.
Article
Materials Science, Multidisciplinary
Lauro A. Pradela-Filho, Juliana L. M. Gongoni, Iana V. S. Arantes, Davi M. De Farias, Thiago R. L. C. Paixao
Summary: Inkjet printing parameters significantly affect the electrical properties of electrochemical sensors. This study explores the impact of temperature, ink drop spacing, length, and ink layer number on the printing quality and electroactive surface area. The optimal parameters for fully printed silver ink sensors are PVC tape at 40 degrees C, 17 mu m drop spacing, one layer, and 13 mm length. These sensors demonstrate batch-to-batch reproducibility and are effective for detecting picric acid, hydrogen peroxide, and glucose.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Analytical
Lauro A. A. Pradela-Filho, William B. B. Veloso, Debora N. Medeiros, Renato S. O. Lins, Bruno Ferreira, Mauro Bertotti, Thiago R. L. C. Paixao
Summary: This study proposes a simple fabrication method for electrochemical sensors using a commercial filament based on polylactic acid and carbon black (PLA/CB). The electrodes were engineered using a three-dimensional (3D) printing pen and poly(methyl methacrylate) template. Optimizing parameters such as electrode thickness and diameter were important to ensure analytical signal integrity. The fabricated electrodes exhibited reproducibility, renewability, and comparable electrochemical responses to traditional glassy carbon electrodes, making them promising platforms for sensing applications including polyphenolic quantification in tea samples and designing electrode arrays for paper-based microfluidic systems.
ANALYTICAL CHEMISTRY
(2023)
Article
Electrochemistry
William B. Veloso, Thiago R. L. C. Paixao, Gabriel N. Meloni
Summary: The limitations in the voltammetric response of 3D printed electrodes are studied using numerical simulations and new electrode designs. Severe diffusion limitations are found in a commonly used 3D printed electrode and electrochemical cell design, hindering the investigation of electron transfer kinetics. A new non-recessed electrode design is used to study the voltammetric response without mass transport limitations, revealing that the response is limited by contact resistance. By considering contact resistance and finite electron transfer kinetics, the peak potentials and currents of voltammograms recorded with 3D printed electrodes can be predicted before printing, allowing for optimized electrode designs in the virtual space.
ELECTROCHIMICA ACTA
(2023)
Review
Chemistry, Analytical
Lauro A. Pradela-Filho, William B. Veloso, Iana V. S. Arantes, Juliana L. M. Gongoni, Davi M. de Farias, Diele A. G. Araujo, Thiago R. L. C. Paixao
Summary: Paper-based analytical devices (PADs) are inexpensive and portable platforms that have been introduced as promising analytical tools for rapid, reliable, and simple testing. They have been used to monitor environmental, health, and food issues. This review provides an overview of the chronological events involving PADs, discusses the fundamental parameters for designing new analytical platforms, and explores the main analytical techniques used in detection systems. It also highlights recent advances in PADs, including dual/combined detection systems and distance-based detection, and critically examines the practical specifications and challenges of these analytical platforms.
Article
Chemistry, Analytical
Jessica Soares Guimaraes Selva, Mauro Bertotti
Summary: This study reports on the fabrication and long-term application of a pH Au microelectrode based on an iridium oxide film. The iridium oxide film, with a thickness of approximately 1 μm, was uniformly coated on the microelectrode surface using a 2-step procedure involving electrodeposition and continuous voltammetric scans. The iridium oxide film exhibited a super-Nernstian slope of 77 mV per pH unit, and the IrO x sensor showed a short-term pH precision of +/- 0.1 pH, excellent reproducibility, long-term stability, and a short response time of less than 10 s. These results confirm the promising pH sensing performance of iridium oxide and its potential application as an electrode material for detecting local pH changes in complex samples such as juices, culture media, synthetic urine, and blood.
BRAZILIAN JOURNAL OF ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Vanessa N. Ataide, Lauro A. Pradela-Filho, Wilson A. Ameku, Masoud Negahdary, Thawan G. Oliveira, Berlane G. Santos, Thiago R. L. C. Paixao, Lucio Angnes
Summary: Paper-based electrochemical analytical devices (ePADs) have gained significant interest due to their simplicity, low cost, portability, and applicability in various fields. Electrochemical biosensors, especially those based on paper, offer attractive advantages such as disease diagnosis and decentralized analysis. This review focuses on recent advancements in paper-based electrochemical devices for detecting viruses, including COVID-19, Dengue, Zika, Hepatitis, Ebola, AIDS, and Influenza, and discusses fabrication methods, device designs, and biomolecule immobilization strategies. The challenges and perspectives for further applications of paper-based electrochemical biosensors are also critically addressed.
Article
Chemistry, Analytical
Masoud Negahdary, William Barros Veloso, Raphael Prata Bacil, Rafael Martos Buoro, Ivano Gebhardt Rolf Gutz, Thiago Regis Longo Cesar Paixao, Claudimir Lucio do Lago, Solange Kazumi Sakata, Gabriel Negrao Meloni, Mesaque Carvalho Franca, Thawan Gomes de Oliveira, Wilson Akira Ameku, Michelangelo Durazzo, Lucio Angnes
Summary: This study successfully detected beta-amyloid (A beta((1-42))), an important biomarker for diagnosing Alzheimer's disease (AD), using an electrochemical aptasensing platform. An innovative signal transducer, a CO2 laser-ablated 3D-printed electrode modified with leaf-shaped gold nanodendrites (LSG NDs), was developed to provide an efficient interface for immobilizing aptamer strands. The modified electrode with LSG NDs showed a significant enhancement in electrochemically active surface area, amplifying electrochemical signals and providing a highly sensitive infrastructure for analyte detection. The developed aptasensor demonstrated stability, reproducibility, regeneration, and minimal interference from other agents, and the application of this aptasensor was successfully monitored in spiked analyte concentrations in 20 samples including cerebrospinal fluid (CSF) and human serum.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Carlos E. C. Lopes, Lucas V. de Faria, Diele A. G. Araujo, Eduardo M. Richter, Thiago R. L. C. Paixao, Luiza M. F. Dantas, Rodrigo A. A. Munoz, Iranaldo S. da Silva
Summary: In this study, a 3D-printed electrode was manufactured using a conductive filament and used for the detection of antibiotics. By improving the electrode preparation method, the fouling phenomenon on the electrode surface was solved, and comparable analytical performance to conventional electrodes was achieved. This method is suitable for routine analysis of environmental, pharmaceutical, and food samples.
Review
Chemistry, Analytical
Vanessa Neiva Ataide, Lauro Antonio Pradela Filho, Barbara Guerra Souza Guinati, Nikaele Sousa Moreira, Juliana Duarte Goncalves, Camilla Machado Gentil Ribeiro, Daniel Grasseschi, Wendell Karlos Tomazelli Coltro, Maiara Oliveira Salles, Thiago Regis Longo Cesar Paixa
Summary: Paper-based Analytical Devices (PADs) have revolutionized chemical sensor development in point-of-need detection and diagnostics by utilizing chemometrics techniques to extract a large quantity of information. This article reviews recent progress on PADs using different analytical techniques (Colorimetric, Electrochemical, SERS, and Fluorescence) and their combination with chemometrics, highlighting their combined advantages in generating powerful analytical platforms. The pioneering studies in the field of paper-based sensing are critically reviewed, along with future challenges to overcome.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Jennifer Rozendo, Marco A. S. Garcia, Scarllett L. S. Lima, Nikola Tasic, Birkan Emrem, Jhonatan L. Fiorio, Guillermo Solorzano, Andre H. B. Dourado, Luis M. Goncalves, Thiago R. L. C. Paixao, Jan-Ole Joswig, Anderson G. M. da Silva, Pedro Vidinha
Summary: This study reveals the effect of different surface facets of gold nanocrystals on the electrocatalytic sensing activities of benzocaine. Results show that the rhombic dodecahedra nanocrystals enclosed by {110} facets exhibit the strongest interaction energy with benzocaine and the highest adsorption capability.
SURFACES AND INTERFACES
(2023)
