Article
Multidisciplinary Sciences
Jung Kyong Shin, Hee Cheol Kim, Woo Yong Lee, Seong Hyeon Yun, Yong Beom Cho, Jung Wook Huh, Yoon Ah Park
Summary: Intersphincteric resection (ISR) for low-lying rectal cancer aims to avoid abdominoperineal resection (APR). This study compared open and minimally invasive ISR, finding similar 5-year disease-free survival rates. Minimally invasive ISR showed advantages in postoperative outcomes like reduced surgical site infection and shorter hospital stay.
SCIENTIFIC REPORTS
(2021)
Article
Surgery
Ziwei Zeng, Zhihang Liu, Shuangling Luo, Zhenxing Liang, Liang Huang, Lei Ruan, Junji Chen, Haiqing Jie, Wenfeng Liang, Huashan Liu, Liang Kang
Summary: There were no significant differences in the 3-year local recurrence rate between the taTME and laTME groups. Additionally, the disease-free survival and overall survival rates within 3 years after surgery were also similar between the two groups.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Justin A. Maykel, Sue J. Hahn, Catherine C. Beauharnais, David C. Meyer, Susanna S. Hill, Paul R. Sturrock, Jennifer S. Davids, Karim Alavi
Summary: This study retrospectively investigated the oncologic outcomes of transanal total mesorectal excision in patients with primary rectal cancer. The results showed good pathological quality, no local recurrence, a distant metastasis rate of 13.5%, and no intraoperative complications. Overall survival and disease-free survival were both high.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Oncology
Severin Gloor, Gioia Pozza, Rebekka Troller, Markus Wehrli, Michel Adamina
Summary: A study of 165 patients with distal rectal cancer who underwent taTME found that this procedure is a viable alternative to conventional TME, with high surgical quality and favorable outcomes.
Article
Surgery
Toshiyuki Adachi, Daichi Kitaguchi, Koichi Teramura, Hiro Hasegawa, Koji Ikeda, Yuichiro Tsukada, Yuji Nishizawa, Takeshi Sasaki, Masaaki Ito
Summary: This retrospective study compared the short-term outcomes of transanal and laparoscopic total mesorectal excisions for low and middle rectal cancers. The transanal group had significantly shorter operative times, lower positive circumferential resection margins rates, and lower incidence of grade III and IV complications compared to the laparoscopic group. This demonstrates the safety and usefulness of transanal total mesorectal excision for middle and low rectal cancers.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Gabie K. B. Ong, Ben Tsai, Roger Lozano Patron, Olaf Johansen, Frederick Lane, R. Barry Melbert, Tobi Reidy, Dipen Maun
Summary: This study compared the efficacy of transanal total mesorectal excision (taTME) and laparoscopic total mesorectal excision (laTME) for the treatment of low rectal cancer. While taTME had longer operative times and higher rates of postoperative fecal incontinence compared to laTME, there were no significant differences in oncologic resection and frequency of positive distal margins.
AMERICAN JOURNAL OF SURGERY
(2021)
Article
Surgery
Jingqing Ren, Shaojie Liu, Huixing Luo, Bailin Wang, Fan Wu
Summary: There was no significant difference in short-term efficacy between TaTME and LaTME for low rectal cancer, but TaTME had a longer operation time and a greater circumferential resection margin distance.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Medicine, General & Internal
Antonio Caycedo-Marulanda, Lawrence Lee, Sami A. Chadi, Chris P. Verschoor, Jordan Crosina, Shady Ashamalla, Carl J. Brown
Summary: The study found that transanal TME performed by experienced surgeons had a low incidence of local recurrence and systemic recurrence, suggesting it may be an acceptable approach for rectal cancer management.
Article
Gastroenterology & Hepatology
Ziwei Zeng, Zhihang Liu, Liang Huang, Huashan Liu, Haiqing Jie, Shuangling Luo, Xingwei Zhang, Liang Kang
Summary: The study compared the learning curves and outcomes of transanal total mesorectal excision with laparoscopic total mesorectal excision, finding that in different phases of the learning curve, operative time, intraoperative blood loss, and postoperative stay were significantly lower in the transanal group, with similar short-term and histopathologic outcomes between the two groups.
DISEASES OF THE COLON & RECTUM
(2021)
Article
Surgery
Rebecca Svensson Neufert, Fredrik Jorgren, Pamela Buchwald
Summary: This study found that rectal washout during anterior resection for rectal cancer does not impact the oncological outcome at 3 years, but a reduction in local recurrence risk was observed after 5 years.
Article
Gastroenterology & Hepatology
Liang Kang, Ziwei Zeng, Shuangling Luo, Hong Zhang, Quan Wang, Mingyang Ren, Miao Wu, Weidong Tong, Qing Xu, Yi Xiao, Aiwen Wu, Yuan-Guang Chen, Bo Feng, Zhanlong Shen, Liang Huang, Xingwei Zhang, Minhua Zheng, Jian-Ping Wang
Summary: The TaLaR trial aims to compare short-term and long-term outcomes between taTME and lapTME for rectal cancer patients. The primary endpoints include the 3-year disease-free survival rate and the 5-year overall survival rate, while secondary endpoints focus on specimen quality, perioperative results, pelvic and anal function, and quality of life.
GASTROENTEROLOGY REPORT
(2021)
Article
Surgery
Zhengbiao Li, Qi Wang, Weiwei Ning, Qinxu Yang, Yong Huang, Shuai Yan, Bo Yang, Ming Xie
Summary: This study compares the clinical use of transanal total mesorectal excision (TaTME) and laparoscopic intersphincteric resection (ISR) as anus-preserving surgeries for low rectal cancer. The results show that TaTME surgery is comparable to ISR surgery in terms of surgical safety and short-term efficacy, but it has better long-term anal function and quality of life. Therefore, from the perspective of long-term anal function and quality of life, TaTME surgery is a better surgical method for the treatment of low rectal cancer.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Gastroenterology & Hepatology
Julie Flynn, Jose T. Larach, Joseph C. H. Kong, Peadar S. Waters, Jacob J. McCormick, Satish K. Warrier, Alexander Heriot
Summary: Robotic rectal cancer resection improves male sexual and urinary functions compared with laparoscopy, but there is no difference in quality of life or GI function. Future studies should report all facets of functional outcomes using standardized scoring systems.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Oncology
Yueh-Chen Lin, Ya-Ting Kuo, Jeng-Fu You, Yih-Jong Chern, Yu-Jen Hsu, Yen-Lin Yu, Jy-Ming Chiang, Chien-Yuh Yeh, Pao-Shiu Hsieh, Chun-Kai Liao
Summary: This study compared the short- and long-term outcomes of transanal total mesorectal excision (TaTME) and laparoscopic total mesorectal excision (LapTME) in treating patients with lower rectal cancer. The results showed that TaTME had similar histopathological results and postoperative outcomes as LapTME, even in the learning curve. Additionally, TaTME demonstrated better disease-free survival and fewer local recurrence events.
Article
Surgery
Xianhao Yi, Xuan Zhang, Qingchun Li, Jun Ouyang
Summary: According to the findings of this meta-analysis, based on RCTs and prospective studies, taTME appears to have an advantage over laTME in terms of conversion rate and CRM involvement.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Oncology
Yuchao Liu, Zijia Liu, Liangyan Zhang, Yuelun Zhang, Ningchen Zhang, Yue Han, Le Shen
Summary: This study found an association between preoperative 6-min walk distance and postoperative complications in patients undergoing laparoscopic gastrointestinal cancer surgery.
Review
Oncology
Matteo Pavone, Rosa Autorino, Nicolo Bizzarri, Giuditta Chilorio, Vincenzo Valentini, Giacomo Corrado, Gabriella Ferrandina, Gabriella Macchia, Maria Antonietta Gambacorta, Giovanni Scambia, Denis Querleu
Summary: Ovarian transposition is an established method for protecting the ovaries from radiation, while surgical procedures for protecting the uterus are still under investigation. This study conducted a systematic review of uterine displacement techniques and performed dose simulation to assess the radiation dose received by the uterus. The results showed that the transposition approach was the most protective.
Article
Oncology
Silvia Ministrini, Maria Bencivenga, Federica Filippini, Gianni Mura, Carlo Milandri, Maria Antonietta Mazzei, Giulio Bagnacci, Mattia Berselli, Manlio Monti, Paolo Morgagni, Leonardo Solaini, Daniele Marrelli, Stefania Piccioni, Stefano De Pascale, Luigina Graziosi, Rossella Reddavid, Fausto Rosa, Claudio Belluco, Guido Tiberio
Summary: The Italian Research Group for Gastric Cancer developed a prospective database to evaluate the impact of a pragmatic attitude on the management of stage IV gastric cancer patients. The study found that different metastatic sites did not affect survival rates, but multiple metastatic sites were associated with worse survival. Patients who could undergo curative resection had better survival rates. A more accurate diagnostic workup and staging had a favorable impact on survival.
Article
Oncology
Luca Lambertini, Fabrizio Di Maida, Anna Cadenar, Samuele Nardoni, Antonio Andrea Grosso, Francesca Valastro, Pietro Spinelli, Riccardo Fantechi, Agostino Tuccio, Gianni Vittori, Andrea Mari, Lorenzo Masieri, Andrea Minervini
Summary: The aim of this study was to evaluate the functional outcomes of Florence intracorporeal neobladder (FloRIN) configuration technique performed with a stentless procedure. The results showed that the stentless procedure was associated with shorter console time and lower estimated blood loss compared to the stent group. There were no significant differences in terms of perioperative features and mid-term functional outcomes between the two groups.
Article
Oncology
Geun-Jeon Kim, Jooin Bang, Hyun-Il Shin, Sang-Yeon Kim, Dong -Il Sun
Summary: This study evaluated the outcome of tonsillar cancer managed with neoadjuvant chemotherapy followed by surgery. The results showed that neoadjuvant chemotherapy reduced tumor volume and pathological adverse features, significantly decreasing the need for adjuvant therapy. A greater reduction in tumor volume predicted a complete pathologic response. There was no significant difference in survival rates between the groups.
Article
Oncology
Alexandra Nassar, Stylianos Tzedakis, Ugo Marchese, Gaanan Naveendran, Remy Sindayigaya, Martin Gaillard, Francois Cauchy, Mickael Lesurtel, Brice Gayet, Olivier Soubrane, David Fuks
Summary: This study identified recurrence between the two stages and a larger tumor size in the future liver remnant as critical factors contributing to the failure of two-stage hepatectomy for bilobar colorectal liver metastases. These findings have important clinical implications for the selection and evaluation of TSH surgery.
Letter
Oncology
Michele Fiore, Gian Marco Petrianni, Gabriele D'Ercole, Pasquale Trecca, Sara Ramella
Review
Oncology
Harry Farrow, Oliver J. Pickering, James A. Gossage, Philip H. Pucher
Summary: The inclusion or exclusion of the thoracic duct in radical esophagectomy for esophageal cancer is a controversial issue. While removing the thoracic duct may increase lymph node yield, it may also lead to higher morbidity without any survival benefit.
Article
Oncology
Xiaokun Li, Siyuan Luan, Chi Zhang, Weili Kong, Xin Xiao, Haowen Zhang, Jianfeng Zhou, Yushang Yang, Yang Xu, Yong Qiang, Pinhao Fang, Yi Shen, Yong Yuan
Summary: This study proposes a new staging system based on ypTNM stage and cN status for early stage ESCC patients after nCRT. The new ypTNM-cN staging system demonstrates superior predictive ability and classification efficacy compared to the AJCC 8th ypTNM staging system. It provides new insights for accurately stratifying ypI stage ESCC patients.