Article
Marine & Freshwater Biology
Xueyou Li, Xiaoxu He, Xiaona Lin, Weihao Li, Jiahao Gao, Ning Zhang, Yusong Guo, Zhongduo Wang, Na Zhao, Bo Zhang, Zhongdian Dong
Summary: This study investigated the effects of bisphenol compounds (BPA, BPS, BPF, and BPAF) on the early growth and development of aquatic organisms using marine medaka larvae. The results showed that these compounds have toxic effects on the cardiovascular system of the larvae, causing neurotoxicity and endocrine disruption. Functional enrichment analysis suggested that the main toxic effects of bisphenols on marine medaka larvae targeted the liver and heart, mainly affecting lipid metabolism and cardiac muscle contraction. This study provides a theoretical foundation for evaluating the toxicological effects of bisphenols on the early development of aquatic organisms.
AQUATIC TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Kaikai Liu, Jingjing Song, Wendan Chi, Hongjun Liu, Shanshan Ge, Daode Yu
Summary: The study found that nickel exposure had significant toxic effects on the early development of marine fish, affecting egg size, heart rate, hatchability, deformity rate, and total body length of newly hatched larvae. Embryos were more sensitive to nickel than larvae, with specific genes showing altered expressions in response to nickel exposure.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Environmental Sciences
Xian Qin, Keng Po Lai, Rudolf Shiu Sun Wu, Richard Yuen Chong Kong
Summary: This study investigated the effects of continuous exposure to 17 alpha-ethinylestradiol (EE2) on reproductive performance in marine medaka fish. The results showed that continuous EE2 exposure reduced fecundity and sperm motility, and caused dysregulation in testicular transcriptome. Key genes identified in this study can serve as biomarkers for assessing EE2-induced reduction in sperm motility.
MARINE POLLUTION BULLETIN
(2022)
Article
Environmental Sciences
Yu Ting Zhang, Mengyun Chen, Shuiqing He, Chao Fang, Mingliang Chen, Dan Li, Dong Wu, Melissa Chernick, David E. Hinton, Jun Bo, Lingtian Xie, Jingli Mu
Summary: This study found that different types of microplastics did not significantly affect the locomotor activity of marine medaka larvae, while exposure to triphenyl phosphate (TPhP) resulted in decreased mobility. However, in the binary mixture exposure of TPhP and microplastics, the presence of microplastics was able to reverse the decrease in mobility caused by TPhP.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Marine & Freshwater Biology
Jiarui Gu, Meng Yan, Priscilla T. Y. Leung, Li Tian, Veronica T. T. Lam, Shuk Han Cheng, Paul K. S. Lam
Summary: The study found that exposure to C. tropicalis lysates can have toxic effects on the behavior, physiology, and molecular responses of larval marine medaka, including inhibiting swimming activity, inducing developmental abnormalities, and causing changes in gene expression related to apoptosis, inflammatory response, oxidative stress, and energy metabolism.
AQUATIC TOXICOLOGY
(2021)
Article
Environmental Sciences
Mitsushi Yamamoto, Nobuhiro Kanazawa, Miho Nomura, Yoshifumi Horie, Hideo Okamura
Summary: Bisphenol A (BPA), an endocrine disruptor found in freshwater and marine environments, has been shown to induce feminization in male marine medaka fish. The expression of gonadal soma-derived factor (gsdf) decreased, while liver vitellogenin (vtg) expression increased, indicating the potential use of vtg and gsdf as biomarkers for evaluating the impact of estrogenic endocrine disruptors in O. melastigma.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Environmental Sciences
Sahar Chauffour Mejri, Rejean Tremblay, Celine Audet, Paul S. Wills, Marty Riche
Summary: This review focuses on the difference in essential fatty acid requirements between cold-water and warm-water marine fish species, with cold-water species showing higher demand. Small Florida pompano have satisfactory omega-3 and omega-6 levels in their diet, but potential deficiencies in other essential fatty acids.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Environmental Sciences
Xian Qin, Huiju Lin, Yaru Cao, Rudolf Shiu Sun Wu, Keng Po Lai, Richard Yuen Chong Kong
Summary: Exposure to 17 alpha-ethinylestradiol (EE2) in fish can result in developmental toxicity, including growth retardation, decreased heart rate, delayed eye pigmentation, reduced hatching rate, and impaired larval locomotion. Transcriptional analysis revealed that these impairments are controlled by estrogen receptor and related to eye structure, neuronal and synaptic structure, and behavior. Key factors identified, such as PRKAA2, APOB, EPHB2, OXTR, NR2E3, and POU4F2, could serve as biomarkers for assessing EE2-induced embryo developmental toxicity.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Marine
Jae Hoon Choi, Jun Hyung Ryu, Seung Pyo Gong
Summary: This study investigated the efficient conditions for the aggregate culture of dispersed testicular cells from marine medaka and identified the most effective method and optimal medium composition. The results demonstrated the necessity of certain supplements in the modified culture medium for the formation and expression levels of testicular cell aggregates. Furthermore, the study showed that sperms derived from in vitro cultured testicular aggregates were capable of fertilizing matured oocytes to produce offspring.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2023)
Article
Fisheries
Adam T. Downie, Jeffrey M. Leis, Peter F. Cowman, Mark McCormick, Jodie L. Rummer
Summary: Latitude and body size are important factors affecting swimming performance of larval marine fishes, with evolutionary relationships and habitat also playing a role. Temperate reef fishes show the greatest increase in swimming performance with body length, and reef fishes have higher swimming capacity compared to non-reef fishes due to their larger body sizes. High swimming performance and larger body sizes of reef fishes are likely adaptations to finding specific habitats for settlement.
FISH AND FISHERIES
(2021)
Article
Environmental Sciences
Luyin Wu, Yao Dang, Li-Xia Liang, Yan-Chen Gong, Mohammed Zeeshan, Zhengmin Qian, Sarah Dee Geiger, Michael G. Vaughn, Yang Zhou, Qing-Qing Li, Chu Chu, Ya-Wen Tan, Li-Zi Lin, Ru-Qing Liu, Li-Wen Hu, Bo-Yi Yang, Xiao-Wen Zeng, Yunjiang Yu, Guang-Hui Dong
Summary: This study found that exposure to perfluorooctane sulfonates (PFOS) can cause neurobehavioral abnormalities in zebrafish larvae, affecting their neurodevelopment. This may be related to the increased reactive oxygen species (ROS) levels in the heads of zebrafish larvae and the disrupted dopamine signaling pathway. In addition, PFOS also induces developmental damage, such as increased malformation rate and shorter body length.
Article
Marine & Freshwater Biology
Christopher H. R. Goatley, Simon J. Brandl, Stephen Wroe, David R. Bellwood
Summary: Cryptobenthic reef fish larvae have a highly constrained range of body shapes, with elongate bodies and small fins, likely resulting in poor swimming abilities. Limited dispersal in these larvae may depend on behavioral adaptations, such as flow-refuging, to avoid being washed away from their natal reefs.
Article
Environmental Sciences
Nathan Tam, Richard Yuen Chong Kong, Keng Po Lai
Summary: Previous studies have shown that exposure to polychlorinated biphenyls (PCBs) in fish can lead to alterations in reproductive functions and behavior. However, the effects of embryonic exposure to PCBs or their metabolites on long-term reproductive function in fish have not been studied. In this study, the marine medaka fish was used to assess the reproductive endpoints after embryonic exposure to either PCB 28 or 4'-OH-PCB 65. The results showed that exposure to 4'-OH-PCB 65 feminized the sex ratio and decreased fecundity in the medaka. Additionally, embryonic exposure to 4'-OH-PCB 65 resulted in reduced fertilization, hatching success rate, and sperm motility. To explain these effects, transcriptomic analysis of the gonads was performed, revealing differential expression of genes involved in reproductive functions. Therefore, the long-term reproductive toxicity of PCBs and their metabolites should be considered in environmental risk assessment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Environmental
In-Cheol Yeo, Kyu-Young Shim, Kyuhyeong Kim, Young-Shin Go, Jieun Kim, Dong-Hun Lee, Jae-Seong Lee, Kyung-Hoon Shin, Chang-Bum Jeong
Summary: Despite limited understanding and analysis of the biological fate of nanoplastics, a novel stable carbon isotopic approach has been proposed to detect and quantify nano- and microplastics in complex organic matrices. By quantifying the contribution of plastic particles in the stable carbon isotopes composition in different tissues, tissue-specific bioaccumulation of nano- and microplastics in a fish species has been investigated. The findings shed light on the unique mode of action of nanoplastics' bioaccumulation based on physicochemical properties and have significance in improving our understanding of the tissue-specific bioaccumulation of nanoplastics in aquatic organisms.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2023)
Article
Biochemistry & Molecular Biology
Xueyou Li, Xiaona Lin, Yuebi Chen, Zhongduo Wang, Yusong Guo, Gyamfua Afriyie, Ning Zhang, Zhongdian Dong
Summary: The study analyzed the effect of norethisterone exposure on the transcriptome of marine medaka larvae, revealing significant changes in gene expression related to metabolic and biosynthetic pathways. These transcript level changes may have adverse effects on the growth and development of aquatic organisms.
CHEMISTRY AND ECOLOGY
(2021)
Article
Reproductive Biology
Meiping Tian, Qingyu Huang, Heng Wang, Francis L. Martin, Liangpo Liu, Jie Zhang, Heqing Shen
REPRODUCTIVE TOXICOLOGY
(2019)
Article
Environmental Sciences
Meiping Tian, Liangpo Liu, Jie Zhang, Qingyu Huang, Heqing Shen
Article
Environmental Sciences
Ambreen Alamdar, Meiping Tian, Qingyu Huang, Xiaoyan Du, Jie Zhang, Liangpo Liu, Syed Tahir Abbas Shah, Heqing Shen
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2019)
Article
Environmental Sciences
Jingyi Zhang, Shuang Liang, Ruihong Ning, Jinjin Jiang, Jie Zhang, Heqing Shen, Rui Chen, Junchao Duan, Zhiwei Sun
ENVIRONMENT INTERNATIONAL
(2020)
Article
Cell Biology
Yajie Chen, Ahmed Bilal Waqar, Kazutoshi Nishijima, Bo Ning, Shuji Kitajima, Fumikazu Matsuhisa, Lu Chen, Enqi Liu, Tomonari Koike, Ying Yu, Jifeng Zhang, Yuqing Eugene Chen, Huijun Sun, Jingyan Liang, Jianglin Fan
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
(2020)
Article
Engineering, Environmental
Jinjin Jiang, Yang Li, Shuang Liang, Baiyang Sun, Yanfeng Shi, Qing Xu, Jie Zhang, Heqing Shen, Junchao Duan, Zhiwei Sun
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Article
Environmental Sciences
Shan Liu, Qingyu Huang, Yan Wu, Yi Song, Wei Dong, Mengtian Chu, Di Yang, Xi Zhang, Jie Zhang, Chen Chen, Bin Zhao, Heqing Shen, Xinbiao Guo, Furong Deng
ENVIRONMENT INTERNATIONAL
(2020)
Article
Environmental Sciences
Nabgha-e-Amen, Syed AliMusstjab Akber Shah Eqani, Faiza Khuram, Ambreen Alamdar, Ayesha Tahir, Syed Tahir Abbas Shah, Arshan Nasir, Sundus Javed, Nazia Bibi, Alamdar Hussain, Hifza Rasheed, Heqing Shen
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Environmental Sciences
Tasawar Khanam, Syed Ali Musstjab Akber Shah Eqani, Jie Zhang, Heng Wang, Yongli Zhang, Jianbo Yang, Muhammad Sadiq, Hifza Rasheed, Heqing Shen
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Hematology
Haizhao Yan, Manabu Niimi, Fumikazu Matsuhisa, Huanjin Zhou, Shuji Kitajima, Yajie Chen, Chuan Wang, Xiawen Yang, Jian Yao, Dongshan Yang, Jifeng Zhang, Masami Murakami, Katsuyuki Nakajima, Yao Wang, Enqi Liu, Jingyan Liang, Y. Eugene Chen, Jianglin Fan
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2020)
Review
Biochemistry & Molecular Biology
Heqing Shen, Yike Zhang, Karl -Werner Schramm
Summary: Exploring the etiology of diseases is a key objective in epidemiological studies. Biomonitoring and molecular analysis can help uncover the links between environmental exposure and diseases, providing new research opportunities.
MOLECULAR ASPECTS OF MEDICINE
(2022)
Article
Environmental Sciences
Hongying Gao, Chuan Liu, Heng Wang, Heqing Shen
Summary: This study investigated the flocculation and/or sedimentation of polystyrene nano-plastics (PS-NPs) in salt solutions and protein solutions. The results showed that salt solutions significantly promoted the aggregation of PS-NPs, while protein-coated PS-NPs also aggregated. Moreover, 500 nm PS-CHO particles settled into sedimentation without flocculation. Therefore, Raman spectrometry is suitable for analyzing assembled PS-NPs but not normal PS-NPs.
Article
Toxicology
Maybin Kalubula, Heqing Shen, Tasawar Khanam
TOXICOLOGY REPORTS
(2020)
Article
Environmental Sciences
Liangpo Liu, Heng Wang, Xueyan Li, Meiping Tian, Qingyu Huang, Jie Zhang, Hong Pan, Kai Wen, Qiansheng Huang, Jianbo Yan, Zhendong Tong, Yongli Zhang, Tongjie Zhang, Yingying Zhang, Ben Li, Tong Wang, Heqing Shen
ENVIRONMENT INTERNATIONAL
(2020)
Article
Medicine, Research & Experimental
Jie Wei, Qiongyu Hao, Chengkun Chen, Juan Li, Xikui Han, Zhao Lei, Tao Wang, Yinan Wang, Xiang You, Xiaoxuan Chen, Huasheng Li, Yuxin Ding, Weihao Huang, Yangyang Hu, Shuirong Lin, Heqing Shen, Yi Lin