Article
Multidisciplinary Sciences
Settu Loganathan, Kuppusamy Selvam, Govindaraj Padmavathi, Muthugounder Subramanian Shivakumar, Sengottayan Senthil-Nathan, Arumuga Gounder Sumathi, M. Ajmal Ali, Saeedah M. Almutairi
Summary: Passiflora subpeltata was used to synthesize silver nanoparticles with good antibacterial, antioxidant, anticancer, and larvicidal activities. These green synthesized nanoparticles may have potential applications in the field of biomedicine.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Chemistry, Applied
Baraka Samwel, Ester Innocent, Francis Machumi, William N. Kisinza, Matthias Heydenreich
Summary: Two new arabinofuranosidetridecanol were isolated from Commiphora merkeri exudate, showing larvicidal activity against mosquito species without cytotoxic effects, suggesting their potential for environment-friendly mosquito control.
NATURAL PRODUCT RESEARCH
(2022)
Article
Multidisciplinary Sciences
Atieh Shemshadian, Hassan Vatandoost, Mohammad Ali Oshaghi, Mohammad Reza Abai, Navid Dinparast Djadid, Fateh Karimian
Summary: The study found that Wolbachia bacteria in Cx. quinquefasciatus increase susceptibility to deltamethrin but have no effect on susceptibility to DDT, indicating that the impact of Wolbachia bacteria on insecticide resistance varies depending on the insecticide used.
Article
Agriculture, Multidisciplinary
Michael D. Asemoloye, Nurudeen Sunmola, Gbolagade Jonathan, John Chikwem
Summary: This study found a positive response of oyster mushrooms to different carbon sources for EPS production, with P. floridanus showing the highest antioxidant properties. An EPS concentration of 100 mg L-1 from all mushrooms was sufficient for inhibiting lipid peroxidation. The mushroom extracts in this study all had significant inhibitory effects on Anopheles gambiae.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Agriculture, Multidisciplinary
Rosiane Andrade da Costa, Thais Tavares Baraviera Dutra, Isadora Emanoela Pereira Costa Andrade, Rose Gomes Monnerat, Cristine Chaves Barreto, Simoni Campos Dias
Summary: In this study, the insecticidal activity of 25 peptides and two bacterial strains against two mosquito species was evaluated. The peptide pelgipeptin showed larvicidal activity against both species. The synergistic effect of pelgipeptin with bacterial toxins enhanced its larvicidal activity against Culex quinquefasciatus.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Parasitology
Appadurai Daniel Reegan, Pachaiyappan Saravana Kumar, Antony Cruz Asharaja, Chitra Devi, Sithi Jameela, Kedike Balakrishna, Savarimuthu Ignacimuthu
Summary: The study found that fraction 7 from the ethyl acetate extract of Streptomyces collinus exhibited good larvicidal activity against both Culex quinquefasciatus and Aedes aegypti mosquitoes, with the isolated compound phenyl acetic acid showing the most significant larvicidal effect.
EXPERIMENTAL PARASITOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Omkar U. Kinkar, Arpit Prashar, Beena Yadav, Ashwani Kumar, Ashok B. Hadapad, Ramesh S. Hire, Ravindra D. Makde
Summary: Recombinant Cry11Aa was successfully purified and found to be active against larvae of tropical disease vectors. Detailed biophysical characterization provided crucial insights into the stability and in-vitro behavior of Cry11Aa.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Taires Peniche, Jonatas L. Duarte, Ricardo M. A. Ferreira, Igor A. P. Sidonio, Rosangela S. F. R. Sarquis, Icaro R. Sarquis, Anna E. M. F. M. Oliveira, Rodrigo A. S. Cruz, Irlon M. Ferreira, Alexandro C. Florentino, Jose C. T. Carvalho, Raimundo N. P. Souto, Caio P. Fernandes
Summary: This study investigates the larvicidal activity of the Hyptis suaveolens essential oil nanoemulsion on Cx. quinquefasciatus. The nanoemulsion showed high larvicidal activity at concentrations of 250 and 125 ppm, indicating its potential as a vector control method for tropical diseases.
Article
Pharmacology & Pharmacy
R. Gopi Krishnan, S. Murugesh
Summary: The study demonstrated significant biological activities of methanolic leaf extracts of O. latifolia in terms of antioxidant, cytotoxicity, and larvicidal potential, suggesting its potential for pharmaceutical applications.
JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL
(2021)
Article
Environmental Sciences
D. Mathivanan, Chinnaperumal Kamaraj, S. R. Suseem, Pachiyappan Rajiv Gandhic, Guilherme Malafaia
Summary: This study aimed to explore the potential use of seaweed Sargassum wightii for biosynthesis of TiO2 NPs to control disease-transmitting mosquitoes and evaluate its effect on non-target organisms. The results showed that the synthesized TiO2 NPs exhibited excellent larvicidal activity against Anopheles subpictus and Culex quinquefasciatus mosquitoes, with no adverse effects on Poecilia reticulata fish.
ENVIRONMENTAL RESEARCH
(2023)
Article
Entomology
Ali Reza Akrami, Hassan Vatandoost, Saeid Ghoodarzi, Mohammad Reza Abai, Zahra Toofighi
Summary: This study focused on a plant called Jashir in central-northern Iran and found that essential oils extracted from different parts of the plant exhibited strong larvicidal properties against mosquito larvae. The chemical components of the oils were analyzed using gas chromatography-mass spectrometry, revealing the presence of cyclic monoterpene compounds. The results suggest that cultivating this plant in suitable areas could provide a sustainable source of materials for essential oil extraction and the development of effective biopesticides.
INTERNATIONAL JOURNAL OF TROPICAL INSECT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Muthuraman Ramanathan, Monikandon Sukumaran, Mathiyazhagan Narayanan, Natarajan Devarajan, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Nguyen Thuy Lan Chi, Mythili Saravanan, Kathirvel Brindhadevi
Summary: This study aimed to isolate significant compounds from the crude ethyl acetate extract of Cymodocea serrulata and evaluate their larvicidal and pupicidal activity against Culex quinquefasciatus. The results showed that fraction 7a had strong larvicidal and pupicidal activities and could be used as a mosquito vector control agent.
PROCESS BIOCHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Govindaraju Ramkumar, Ranganathan Muthusamy, Mathiyazhagan Narayanan, Rajendran Dhanapal, Chinnannan Karthik, M. S. Shivakumar, Govindhan Malathi, B. Kariyanna
Summary: Nitro-PAH is a highly toxic substance that can cause pollution and have carcinogenic and immunotoxic effects. UV-B exposure and Nitro-PAH can lead to cellular damage and increased activity of major detoxification enzymes. Additionally, these exposures can make mosquito larvae more susceptible to chemical insecticides.
Article
Entomology
Youhui Gong, Ming Li, Ting Li, Nannan Liu
Summary: This study revealed the potential role of carboxylesterases in the development of permethrin resistance in Cx. quinquefasciatus larvae through transcriptional overexpression, metabolism, and detoxification.
Article
Agronomy
Mohammed Al-Zharani, Mohammed S. Al-Eissa, Hassan A. Rudayni, Daoud Ali, Saud Alarifi, Radhakrishnan Surendrakumar, Akbar Idhayadhulla
Summary: The study synthesized geranylacetone derivatives using a grindstone method based on Mannich condensation, with compound 1f showing high larvicidal activity against Culex quinquefasciatus. It was more toxic to the mosquitoes compared to geranylacetone, but non-toxic to non-target aquatic species, making it a potential candidate for mosquito control.
Article
Pharmacology & Pharmacy
Shramana Koner, Ida Florance, Amitava Mukherjee, Natarajan Chandrasekaran
Summary: This study investigates the toxic effects of polystyrene nanoparticles (PSNPs) on human macrophages. The results show that exposure to PSNPs leads to cytotoxicity, oxidative stress, decreased cell proliferation, decreased mitochondrial membrane potential, and DNA damage in human macrophages.
Article
Multidisciplinary Sciences
Priyadarshini Mohapatra, Natarajan Chandrasekaran
Summary: In this study, the binding interactions between Mefloquine-loaded black cumin seed oil nanoemulsion and human and bovine serum albumin were investigated. Various spectroscopic techniques and molecular docking studies were used to confirm the binding effects. The results showed that the addition of Mefloquine impacted the microenvironment around aromatic amino acid residues in human serum albumin and the binding preference of Mefloquine to human serum albumin was observed.
Article
Engineering, Environmental
S. Swetha, Mostafa A. Abdel-Maksoud, Mohammad K. Okla, B. Janani, Turki M. Dawoud, Mohamed A. El-Tayeb, S. Sudheer Khan
Summary: Photocatalysis is an effective technology for water treatment, and in this study, a n-n heterojunction between Fe-doped Pr6O11-MoO3 and g-C3N4 with a flower-on-sheet morphology (Fe/Pr6O11-MoO3@g-C3N4 NCs) was constructed. The nanomaterials were thoroughly characterized, and it was found that the photogenerated charge carriers were produced through multiple routes. The Fe/Pr6O11-MoO3@g-C3N4 NCs exhibited excellent degradation and disinfection capabilities in water treatment.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Green & Sustainable Science & Technology
B. Harikumar, Mohammad K. Okla, S. Kokilavani, Bander Almunqedhi, Raida Alshuwaish, Mostafa A. Abdel-Maksoud, Mohamed A. El-Tayeb, S. Sudheer Khan
Summary: Researchers developed a visible light photocatalyst composed of N/S doped iron oxide (Fe3O4) decorated on oxygen vacancy enriched WO3 nanorods via a facile hydrothermal method. The prepared photocatalyst demonstrated high efficiency in the degradation of doxycycline and reduction of hexavalent chromium, and exhibited excellent reusability and magnetic property. The degradation end products were found to be non-toxic to bacterial species.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Plant Sciences
Sayani Giri, Abisha Christy Christudoss, Natarajan Chandrasekaran, Willie J. G. M. Peijnenburg, Amitava Mukherjee
Summary: Both BPA and PSNPs are commonly found in consumer products and pose serious threats to the environment and aquatic life. This study examined the toxic effects of PS-NPs and BPA on the microalgae Scenedesmus obliquus, as well as the impact of algal EPS on their interaction. The results showed that EPS-containing mixtures reduced toxicity by decreasing reactive oxygen species levels, antioxidant enzyme activity, and cell membrane damage, leading to improved photosynthetic pigment content in the cells.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Plant Sciences
Swarnali Dey, Shreya Nath, Tauhid Alam Ansari, Ankita Biswas, Falguni Barman, Saikat Mukherjee, Geetha Gopal, Arindam Bhattacharyya, Amitava Mukherjee, Rita Kundu, Subhabrata Paul
Summary: The application of nanomaterials in agriculture has seen extensive exploration in the past decade, resulting in a wide range of nanoparticle-based agrochemicals. Metallic nanoparticles composed of plant macro- and micronutrients have been used as nutritional supplements for plants through various methods. However, most studies have focused on monometallic nanoparticles, limiting their usage and effectiveness. In this study, a bimetallic nanoparticle consisting of copper and iron was used in rice plants to test its efficacy in terms of growth and photosynthesis. Experiment results showed that foliar application of 5 mg L-1 bimetallic nanoparticle increased vigor and photosynthetic efficiency, while a concentration of 10 mg L-1 induced oxidative stress to some extent. Furthermore, the bimetallic nanoparticle treatment did not cause structural anomalies or cytotoxicity in the exposed plant parts. This study not only demonstrates the effectiveness of Cu-Fe bimetallic nanoparticles but also critically explores their safety on rice plants, providing valuable insights for designing new bimetallic nanoparticles and exploring their efficacy.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Plant Sciences
Abisha Christy Christudoss, Christian O. Dimkpa, Amitava Mukherjee
Summary: This study investigated the toxicity of graphene oxide (GO) on Allium cepa root tip cells and found that GO caused various toxic effects, especially genotoxicity. The extracellular polymeric substances (EPS) potentially played a role in reducing the toxic effects by decreasing oxidative stress.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Multidisciplinary Sciences
A. N. K. V. Sravani, Natarajan Chandrasekaran, John Thomas, Amitava Mukherjee
Summary: This study developed a new cisplatin loaded hydroxyl functionalized single-walled carbon nanotube nanocarrier system to selectively eliminate gastric cancer stem cells, overcoming the resistance caused by non-specific and non-targeted drug delivery by chemotherapy.
Article
Chemistry, Analytical
Soupam Das, Amitava Mukherjee
Summary: Disposable surgical face masks used during COVID-19 outbreak release microplastics into water, along with titanium dioxide nanoparticles (nTiO(2)). The leached microplastics from the masks were identified as polypropylene of varying sizes. In addition, heavy metals leached from the masks, combined with nTiO(2), pose a severe environmental threat as they cause cellular damage, decrease photosynthesis, and increase oxidative stress in algae.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2023)
Article
Environmental Sciences
Soupam Das, Sayani Giri, Gaurav Wadhwa, Mrudula Pulimi, Shalini Anand, Natarajan Chandrasekaran, Seyed Ali Johari, Pramod Kumar Rai, Amitava Mukherjee
Summary: Due to their remarkable properties, the applications of carbon-based nanomaterials (CNMs) such as graphene and functionalized multi-walled carbon nanotubes (f-MWCNTs) are increasing. These CNMs can enter the freshwater environment and potentially expose various organisms. The study found that both graphene and f-MWCNTs caused toxic effects on freshwater algae species, including a decrease in cell viability, esterase activity, and photosynthetic efficiency. The binary mixture of the pollutants showed a synergistic enhancement of the toxic potential. Oxidative stress played a critical role in the toxicity responses. The study highlights the importance of considering the combined effects of CNMs in evaluating ecotoxicity in freshwater organisms.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
M. Camil Rex, Abhrajit Debroy, M. Joyce Nirmala, Amitava Mukherjee
Summary: The unsustainable manufacturing, utilization and inadequate handling of plastics have caused a significant increase in global plastic pollution. There is growing concern about the potential hazards associated with exposure to micro/nanoplastics (M/NPs). Understanding the environmental behavior of M/NPs, particularly in aquatic systems, where they are likely to accumulate, is crucial. The formation of a biocorona (BC) through interaction with biomolecules within aquatic organisms modifies the physicochemical attributes of M/NPs, such as size, stability, and surface charge. This review discusses the concept of BC formation, analytical techniques for characterizing it, and its implications on the toxicity, fate, and transport of M/NPs in the environment.
Article
Engineering, Environmental
L. Sruthi, Mohammad Asad, Muhammad Nadeem Arshad, Abdullah M. Asiri, S. Sudheer Khan
Summary: Heavy metal-organic complexes are widespread in contaminated waters and pose a greater challenge for decontamination compared to free ions. Current analytical methods are unable to determine these complexes, impeding the development of decontamination mechanisms. A highly sensitive and selective colorimetric sensor for detecting Cr3+/Hg2+-organic complexes using citrate functionalized silver nanoparticles (Ag NPs) has been developed. The sensor exhibits nanomolar scale detection and its application could greatly advance the instant colorimetric detection of heavy metals in the environment.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Environmental Sciences
Pazhamthavalathil Anil Athulya, Zachariah Sunil, Sonia Manzo, Natarajan Chandrasekaran
Summary: This study examines the effects of microplastics and low pH on the physiology and development of Artemia salina through exposure experiments. The results indicate that the combined exposure to microplastics and low pH induces oxidative stress and adversely affects the development of Artemia salina. These findings underscore the need for further research on the combined toxicological impacts of ocean acidification and predominant pollutants like microplastics on other marine animals.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Chemistry, Analytical
Abisha Christy Christudoss, Natarajan Chandrasekaran, Amitava Mukherjee
Summary: Due to the escalating risk of plastic pollution, nanoplastics have received significant attention. A study examined the individual and combined effects of fluorescent polystyrene nanoplastics (FNPs) and diclofenac (DCF) on Scenedesmus obliquus. The toxicity of S. obliquus significantly increased upon exposure to DCF and FNPs, with oxidative stress being the major cause. When FNPs and DCF were mixed, a synergistic or antagonistic effect was observed depending on the concentrations. Oxidative stress parameters, antioxidant enzyme activity, and pigment content in the algae validated the cytotoxicity data. The study highlights the hazardous nature of nanoplastics and their co-exposure risks with pharmaceuticals.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2023)
Review
Chemistry, Multidisciplinary
Durgalakshmi Rajendran, Natarajan Chandrasekaran
Summary: This paper presents a thorough assessment of the toxicity and mechanism of action of micro- and nanoplastics (MNPs) in the bloodstream. MNPs can cause various toxic effects, including plasma protein denaturation, hemolysis, reduced immunity, thrombosis, and vascular endothelial damage, among others, which can lead to life-threatening diseases. The key mechanisms of toxicity include protein corona formation, oxidative stress, cytokine alterations, inflammation, and cyto- and genotoxicity. There are research gaps regarding the combined toxicity of MNPs and co-pollutants, real-world MNPs toxic impacts, bioaccumulation, dose-response relationships, and the effect of different physiochemical characteristics of MNPs.
