Review
Pharmacology & Pharmacy
Maria Popescu, Talia B. Feldman, Tanuja Chitnis
Summary: This study examines the impact of endocrine disruptors on gender bias in autoimmune diseases, highlighting how environmental factors may interfere with immune-related endocrine signaling and potentially lead to autoimmunity. It also emphasizes that the heterogeneity in research on endocrine disruptors may pose challenges in interpreting and translating results.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Environmental Sciences
Zorimar Rivera-Nunez, Carolyn W. Kinkade, Leena Khoury, Jessica Brunner, Hannah Murphy, Christina Wang, Kurunthachalam Kannan, Richard K. Miller, Thomas G. O'Connor, Emily S. Barrett
Summary: The study found that maternal serum levels of poly- and perfluoroalkyl substances (PFAS) are associated with sex steroid hormone levels during pregnancy. Specifically, PFHxS is associated with increased testosterone levels in male fetuses, while PFNA and PFDA are associated with increased free testosterone levels in male fetuses. For female fetuses, PFHxS is associated with increased levels of estradiol and estriol. No associations were found for PFOS and PFOA.
ENVIRONMENTAL RESEARCH
(2023)
Article
Biochemical Research Methods
Brett R. Blackwell, Gerald T. Ankley
Summary: This study developed a method for the simultaneous measurement of thirteen endogenous steroids in small sample volumes without derivatization, validating the concentrations of steroids and demonstrating potential application in aquatic toxicology studies for identifying EDCs.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Review
Cell Biology
Rachel Bleach, Mark Sherlock, Michael W. O'Reilly, Marie McIlroy
Summary: IGF signaling plays a crucial role in tumor growth, with complex interactions with sex hormones and endocrine-driven cancers. IGF-1 plays a compensatory role in ER and AR by enhancing hormonal responses, and dysregulated IGF signaling is associated with breast and prostate cancers.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Veterinary Sciences
Agnieszka Wesolowska
Summary: The sex of a host influences the intensity, prevalence, and severity of helminth infection. In many cases, males are more susceptible to helminth infections than females, but there are also exceptions. This sex bias is primarily caused by ecological, behavioral, and physiological differences, and it is influenced by complex interactions between sex hormones, sex chromosomes, the microbiome, and the immune system.
VETERINARY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Katelyn A. Bruno, Logan P. Macomb, A. Carolina Morales-Lara, Jessica E. Mathews, J. Augusto Frisancho, Alex L. Yang, Damian N. Di Florio, Brandy H. Edenfield, Emily R. Whelan, Gary R. Salomon, Anneliese R. Hill, Chathuranga C. Hewa-Rahinduwage, Ashley J. Scott, Henry D. Greyner, Frank A. Molina, Merci S. Greenaway, George M. Cooper, DeLisa Fairweather
Summary: The study found that housing mice in plastic cages increases the progression of viral myocarditis, with male mice being mainly affected by complement activation and increased macrophages, while female mice are mainly affected by mast cell activation and fibrosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
John Dou, Soundara Viveka Thangaraj, Muraly Puttabyatappa, Venkateswaran Ramamoorthi Elangovan, Kelly Bakulski, Vasantha Padmanabhan
Summary: Inappropriate developmental exposure to steroids, such as prenatal testosterone excess or bisphenol A (BPA), has been linked to metabolic disorders. This study sequenced non-coding RNA (ncRNA) from different adipose depots of animals treated with prenatal testosterone and BPA, and found depot-specific changes in ncRNA that are consistent with depot-specific mRNA expression. These changes are associated with insulin resistance, adipocyte differentiation, and cardiac hypertrophy.
MOLECULAR AND CELLULAR ENDOCRINOLOGY
(2023)
Article
Environmental Sciences
Pan Yang, Bi-Gui Lin, Bin Zhou, Wen-Cheng Cao, Pan-Pan Chen, Yan-Ling Deng, Jian Hou, Sheng-Zhi Sun, Tong-Zhang Zheng, Wen-Qing Lu, Li-Ming Cheng, Wan-Jiang Zeng, Qiang Zeng
Summary: The study found that prenatal exposure to BPA, BPF, and BPS can have detrimental effects on fetal growth, with stronger effects noted in female infants. Associations were observed with birth length, ponderal index, and gestational age, showing different relationships with fetal growth parameters.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Razegheh Akhbarizadeh, Giacomo Russo, Sergio Rossi, Katarina Golianova, Farid Moore, Marco Guida, Maria De Falco, Lucia Grumetto
Summary: The study revealed the presence of various endocrine disrupting chemicals in two widely consumed fish species from the Persian Gulf, with DEHP being the most frequently detected compound. The concentrations of EDCs were generally higher in the liver than in the muscle, and consuming two fish-based meals per week may pose a moderate risk, especially for vulnerable population groups.
MARINE POLLUTION BULLETIN
(2021)
Article
Endocrinology & Metabolism
Sagi Enicole A. Gillera, William P. Marinello, Kevin T. Cao, Brian M. Horman, Heather M. Stapleton, Heather B. Patisaul
Summary: The study found that developmental exposure to the common FR mixture Firemaster 550 has gender-specific effects on social behaviors and neuronal populations in prairie voles. Exposed females showed changes in AVP neurons while exposed males had alterations in dopaminergic neurons, indicating potential endocrine disruption on OT/AVP pathways and coordination of behaviors.
Article
Biochemistry & Molecular Biology
Nolwenn Adam, Sakina Mhaouty-Kodja
Summary: Phthalates have been shown to have reproductive toxic effects in male rodents, and can also impact the female rodent brain. Research indicates that exposure to phthalates may affect behaviors in female rodents, highlighting the need for further investigation to assess the potential risks to human health.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Martina Capriotti, Paolo Cocci, Luca Bracchetti, Erika Cottone, Rosaria Scandiffio, Giovanni Caprioli, Gianni Sagratini, Gilberto Mosconi, Patrizia Bovolin, Francesco Alessandro Palermo
Summary: This study presented environmental baseline data on floating microplastics in Italian coastal waters of the Central Adriatic Sea, revealing the presence of various organic pollutants on the surface of collected microplastics. Furthermore, the study indicated potential metabolic effects of microplastics on adipocytes, resulting in both adipogenesis and lipid uptake/storage.
Article
Environmental Sciences
Anna S. Young, Nicholas Herkert, Heather M. Stapleton, Brent A. Coull, Russ Hauser, Thomas Zoeller, Peter A. Behnisch, Emiel Felzel, Abraham Brouwer, Joseph G. Allen
Summary: Humans are exposed to complex mixtures of hormone-disrupting chemicals, and traditional research methods do not evaluate enough chemicals at once. This study used silicone wristbands to investigate exposures to chemical mixtures in office workers from different countries. The results revealed associations between chemical concentrations and hormonal activities, and identified several important chemicals contributing to the overall mixture effects. The study emphasized the role of personal care products and building microenvironments in hormone-disrupting exposures.
Article
Nutrition & Dietetics
Krystyna Makowska, Ewa Lepiarczyk, Slawomir Gonkowski
Summary: Bisphenol A (BPA), commonly used as a plasticizer, has a strong negative effect on living organisms and is being replaced by bisphenol S (BPS) in plastic production. This study compares the impact of BPA and BPS on enteric neurons for the first time using double immunofluorescence technique. Both BPA and BPS affect the number of enteric neurons containing various neuronal factors, with BPS showing a stronger impact on certain neuronal populations. The results indicate that long-term exposure to BPS, even in low doses, is not neutral for enteric neurons and may be more potent than BPA for certain neuronal populations.
Article
Engineering, Environmental
Ioana Chelcea, Stefan Orn, Timo Hamers, Jacco Koekkoek, Jessica Legradi, Carolina Vogs, Patrik L. Andersson
Summary: This article presents a study on the distribution and kinetics of a new class of pollutants, bisphenol Z, in zebrafish. By establishing a physiologically based toxicokinetic model, researchers were able to predict the concentrations of bisphenols in different organs of the zebrafish and found that these bisphenols mainly distribute to the carcass and gonads.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
I. Ben Ammar, S. Milla, H. Missaoui, Y. Ledore, F. Teletchea, P. Fontaine
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2018)
Article
Endocrinology & Metabolism
S. N. M. Mandiki, S. Milla, S. Nkogo Robles, P. Kestemont
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2017)
Article
Agriculture, Dairy & Animal Science
A. Golpour, C. Broquard, S. Milla, H. Dadras, A. R. Baloch, T. Saito, M. Psenicka
REPRODUCTION IN DOMESTIC ANIMALS
(2017)
Article
Reproductive Biology
Daniel Zarski, Gergely Bernath, Jaroslaw Krol, Beata I. Cejko, Zoltan Bokor, Katarzyna Palinska-Zarska, Sylvain Milla, Pascal Fontaine, Slawomir Krejszeff
Article
Agriculture, Dairy & Animal Science
J. Roche, D. Zarski, A. Khendek, I Ben Ammar, C. Broquard, A. Depp, Y. Ledore, T. Policar, P. Fontaine, S. Milla
Article
Agriculture, Dairy & Animal Science
A. Khendek, A. Chakraborty, J. Roche, Y. Ledore, A. Personne, T. Policar, D. Zarski, R. Mandiki, P. Kestemont, S. Milla, P. Fontaine
Article
Biochemistry & Molecular Biology
Sylvain Milla, Sophie Massart, Cedric Mathieu, Neil Wang, Caroline Douny, Jessica Douxfils, Marie-Louise Scippo, Edwin De Pauw, Marc Dieu, Frederic Silvestre, Patrick Kestemont
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2018)
Article
Fisheries
Daniel Zarski, Pascal Fontaine, Jennifer Roche, Maud Alix, Miroslav Blecha, Coralie Broquard, Jaroslaw Krol, Sylvain Milla
Article
Biochemistry & Molecular Biology
Imen Ben Ammar, Sylvain Milla, Yannick Ledore, Fabrice Teletchea, Pascal Fontaine
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2020)
Article
Fisheries
Daniel Zarski, Katarzyna Palinska-Zarska, Slawomir Krejszeff, Jaroslaw Krol, Sylvain Milla, Pascal Fontaine, Zoltan Bokor, Bela Urbanyi
Article
Biochemical Research Methods
Sedigheh Mohammadzadeh, Fatemeh Moradian, Sakineh Yeganeh, Bahram Falahatkar, Sylvain Milla
PROTEIN EXPRESSION AND PURIFICATION
(2020)
Article
Multidisciplinary Sciences
Sebastien Baekelandt, Sylvain Milla, Valerie Cornet, Enora Flamion, Yannick Ledore, Baptiste Redivo, Sascha Antipine, Syaghalirwa N. M. Mandiki, Alexis Houndji, Najlae El Kertaoui, Patrick Kestemont
SCIENTIFIC REPORTS
(2020)
Article
Fisheries
Sylvain Milla, Alain Pasquet, Leila El Mohajer, Pascal Fontaine
Summary: Domestication has significant effects on the phenotypes of teleosts, inducing complex biological changes. However, these changes vary greatly among species and physiological functions. Despite the lack of comprehensive understanding, gathering and clarifying information can help predict the effects of domestication better.
REVIEWS IN AQUACULTURE
(2021)
Article
Biochemistry & Molecular Biology
Jennifer Roche, Sebastien Hergalant, Amandine Depp, Imen Ben Ammar, Anne-Gaelle Lafont, Tomas Policar, Pascal Fontaine, Sylvain Milla
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2020)
Article
Fisheries
Peter Podhorec, Grzegorz Gosiewski, Imen Ben Ammar, Miroslawa Sokolowska-Mikolajczyk, Jaroslaw Chyb, Sylvain Milla, Sergii Boryshpolets, Marek Rodina, Zuzana Linhartova, Daniel Biro, Vlastimil Stejskal, Jan Kouril