Article
Oncology
Katarina Kopcalic, Ivana Z. Matic, Irina Besu, Vesna Stankovic, Zoran Bukumiric, Tatjana P. Stanojkovic, Aleksandar Stepanovic, Marina Nikitovic
Summary: This study aimed to investigate the possible relations between serum concentrations of IL-6 and TGF-beta 1 and adverse effects of radiotherapy in prostate cancer patients. The results showed significant positive associations between diabetes mellitus and changes in acute genitourinary toxicity grades, as well as between smoking and maximum fatigue levels. Furthermore, there were positive correlations between IL-6 and TGF-beta 1 concentrations and genitourinary toxicity grades and fatigue levels.
Article
Toxicology
A. Rump, C. Hermann, A. Lamkowski, T. Popp, M. Port
Summary: This study compared the chemical and radiation toxicity of uranium and thorium, finding that their lethal doses are similar. Thorium-232 is more radiotoxic than uranium when ingesting the same activity, but the radiation toxicity differs when comparing the same weight.
ARCHIVES OF TOXICOLOGY
(2023)
Article
Engineering, Biomedical
Theresa M. Lutz, Ceren Kimna, Angela Casini, Oliver Lieleg
Summary: The slime mold Physarum polycelphalum has been chosen as the unicellular organism of the year 2021, highlighting the overlooked diversity of life forms in nature. This article provides an overview of naturally occurring slimy substances with adhesive properties, categorizing them based on their chemical motifs. It also highlights recent developments in material design and functionalization using these biological compounds for novel applications in medicine.
MATERIALS TODAY BIO
(2022)
Article
Environmental Sciences
Donovan Anderson, Shingo Kaneko, Amber Harshman, Kei Okuda, Toshihito Takagi, Sarah Chinn, James C. Beasley, Kenji Nanba, Hiroko Ishiniwa, Thomas G. Hinton
Summary: Genetic effects and radioactive contamination of wild boar in Fukushima were studied. The concentration of radiocesium in boar decreased over time, but remained high near the power plant. Despite chronic radiation exposure, no significant accumulation of mutation events was found. The effective dose to humans from consuming contaminated wild boar meat was calculated to be below the ingestion limit.
ENVIRONMENTAL POLLUTION
(2022)
Review
Oncology
Siti Hajar Zuber, Noorazrul Yahya
Summary: The study reviewed the distribution of racial/ancestral features and their inclusion in genetic-toxicity association studies following radiation therapy. Most studies involving toxicity-related radiogenomic studies were conducted in Europe and North America, with individual races/ancestries being considered as covariates in some cases. Encouraging multinational studies or Individual Participant Data meta-analyses is necessary to further advance research in this field.
JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
(2021)
Review
Biochemical Research Methods
Hao Li, Junyao Hou, Ziyu Chen, Jingyu Zeng, Yu Ni, Yayu Li, Xia Xiao, Yaqi Zhou, Ning Zhang, Deyu Long, Hongfei Liu, Luyu Yang, Xinyue Bai, Qun Li, Tongtong Li, Dongxue Che, Leijie Li, Xiaodan Wang, Peng Zhang, Mingzhi Liao
Summary: Researchers constructed a fertility index factor database FifBase based on manually curated published literature and RNA-Seq datasets, which contains gene annotation and environmental factors related to fertility. Through literature curation, they obtained 3301 articles related to fecundity from PubMed, involving 2823 genes, and eventually filtered out 1558 genes associated with fertility.
BRIEFINGS IN BIOINFORMATICS
(2021)
Review
Oncology
Sebastian F. Winter, Eugene J. Vaios, Helen A. Shih, Clemens Grassberger, Michael W. Parsons, Melissa M. Gardner, Felix Ehret, David Kaul, Wolfgang Boehmerle, Matthias Endres, Jorg Dietrich
Summary: Proton therapy has advantages over conventional radiotherapy in terms of toxicity profiles and potentially reduces late radiogenic complications. However, the impact of variable biological effectiveness of protons on dose distribution needs further investigation. Clinical trials are underway to establish the long-term treatment outcomes of proton therapy in adults with CNS malignancies.
CURRENT TREATMENT OPTIONS IN ONCOLOGY
(2023)
Review
Environmental Sciences
Mohammad Ehsan Taghavizadeh Yazdi, Mohammad Sadegh Amiri, Fahimeh Nourbakhsh, Mostafa Rahnama, Fatemeh Forouzanfar, Seyed Hadi Mousavi
Summary: Heat shock proteins (HSPs) are a family of proteins expressed by cells in response to stressors, with changes in concentration serving as bio-indicators of oxidative stress caused by heavy metals. Exposure to cadmium ion (Cd2+) can increase the expression of HSP70 and HSP27, with the HSP70 family being more sensitive to Cd intoxication than other HSPs.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Applied
A. Moniakowska, D. Zhang, K. Block-Laszewska, G. Olszewski, A. Zaborska, D. Struminska-Parulska
Summary: This study investigated the levels of radioactive nuclides in algae supplements worldwide and estimated the effective radiation doses from consuming these supplements. The findings suggest that the activity concentrations of radionuclides in algae supplements are low and the supplements can be considered safe for consumption.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Medicinal
Honoka Obata, Atsushi B. Tsuji, Katsushi Kumata, Hitomi Sudo, Katsuyuki Minegishi, Kotaro Nagatsu, Hideo Takakura, Mikako Ogawa, Akihiro Kurimasa, Ming-Rong Zhang
Summary: This study aims to establish new labeling methods for no-carrier-added radio-Pt (191Pt) and evaluate the in vitro properties of 191Pt-labeled agents compared with those of agents labeled with the common emitter 111In. The results showed that 191Pt labeled via DTPA or Cys had a comparable intranuclear fraction to 111In labeled via DTPA, but demonstrated a significantly higher DNA-binding/cellular uptake ratio. This suggests that 191Pt has better DNA targeting capabilities than 111In.
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Olga V. V. Kolesnik, Tatiana V. V. Rozhko, Nadezhda S. S. Kudryasheva
Summary: Radioactive contaminants pose problems globally, particularly in marine ecosystems, and their ecological significance is expected to increase in the future. This review focuses on the bioeffects of various alpha and beta emitting radioisotopes (americium-241, uranium-235/238, thorium-232, and tritium) and gamma radiation, with a special emphasis on low-intensity exposures. Luminous marine bacteria are highlighted as representative organisms, and their bioluminescence intensity is widely used as a simple and sensitive bioassay parameter. The review discusses the relationship between bacterial luminescence response and exposure time and irradiation intensity, and also explores molecular intracellular processes under low-intensity radiation, including changes in enzymatic processes, consumption of NADH, the role of reactive oxygen species, and DNA damage repair. The results demonstrate the natural radioprotective function of humic substances.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Riti Thapar Kapoor, Manar Fawzi Bani Mfarrej, Pravej Alam, Joerg Rinklebe, Parvaiz Ahmad
Summary: Untreated industrial effluents pose adverse effects on human health, environment, and socio-economic aspects. Environmental pollution caused by chromium negatively impacts natural resources and ecosystems. Chromium, a hazardous carcinogenic element released from spontaneous activities and industrial procedures, displays toxicity, mobility, and bioavailability depending on its speciation. Trivalent chromium [Cr(III)] exists as an immobile, less soluble species under reducing conditions, whereas hexavalent chromium [Cr(VI)] is mobile, toxic, and bioavailable under oxidizing conditions. Hexavalent chromium, compared to its trivalent form, is more pernicious. It hinders crop growth, reduces total yield, and affects grain quality. Even at low concentrations, exposure to chromium enhances its accumulation in human and animal cells, leading to detrimental health effects. Various techniques have been used to eliminate chromium pollution, yet selecting a green and cost-efficient technology for treating industrial effluents remains challenging. This review highlights the problems associated with chromium pollution and emphasizes the urgent need for its immediate elimination through suitable remediation strategies. Further investigations are required to fill the existing gaps and overcome the challenges associated with chromium contamination, implementing sustainable remediation strategies with real-time applicability on contaminated sites.
ENVIRONMENTAL POLLUTION
(2022)
Article
Multidisciplinary Sciences
Deyang Xu, Niels Christian Holm Sanden, Line Lykke Hansen, Zeinu Mussa Belew, Svend Roesen Madsen, Lasse Meyer, Morten Egevang Jorgensen, Pascal Hunziker, Dorottya Veres, Christoph Crocoll, Alexander Schulz, Hussam Hassan Nour-Eldin, Barbara Ann Halkier
Summary: Plant membrane transporters control metabolite distribution, contributing to key agronomic traits. Mutations in importers can prevent the accumulation of anti-nutritional factors in edible parts, but may alter the distribution pattern within the plant. Engineering of exporters can prevent these changes while still improving the nutritional quality of the seeds.
Article
Multidisciplinary Sciences
Andrea Bours, Peter Pruisscher, Karen Bascon-Cardozo, Linda Odenthal-Hesse, Miriam Liedvogel
Summary: Transposable elements (TEs) are mobile genetic elements that contribute to genomic variability. Recent advancements in high-quality genome references have provided valuable resources for studying the role of TEs in genetic variation and phenotypic evolution. This study demonstrates the use of TE annotation to understand the distinct effects of recent and ancient TE insertions on genomic variation.
SCIENTIFIC REPORTS
(2023)
Review
Environmental Sciences
Chubin Zhang, Leon Barron, Stephen Sturzenbaum
Summary: The increase of pharmaceuticals in soils poses a threat to soil dwelling organisms, plants, and food webs, but the knowledge about their impacts on soils is limited. Further research on the adsorption, degradation, and accumulation behaviors of pharmaceuticals in soils is essential to enhance our understanding and management strategies.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Laila Omar-Nazir, Xiaopei Shi, Anders Moller, Timothy Mousseau, Soohyun Byun, Samuel Hancock, Colin Seymour, Carmel Mothersill
ENVIRONMENTAL RESEARCH
(2018)
Article
Environmental Sciences
Carmel Mothersill, Michael Abend, Francois Brechignac, George Iliakis, Nathalie Impens, Munira Kadhim, Anders Pape Moller, Deborah Oughton, Gibin Powathil, Eline Saenen, Colin Seymour, Jill Sutcliffe, Fen-Ru Tang, Paul N. Schofield
ENVIRONMENTAL RESEARCH
(2018)
Article
Ornithology
Juan Huo, Canchao Yang, Tongping Su, Wei Liang, Anders Pape Moller
Article
Ornithology
Chunrong Mi, Anders Pape Moller, Yumin Guo
Review
Environmental Sciences
Carmel Mothersill, Michael Abend, Francois Brechignac, David Copplestone, Stanislav Geras'kin, Jessica Goodman, Nele Horemans, Penny Jeggo, William McBride, Timothy A. Mousseau, Anthony O'Hare, Rao V. L. Papineni, Gibin Powathil, Paul N. Schofield, Colin Seymour, Jill Sutcliffe, Brian Austin
ENVIRONMENTAL RESEARCH
(2019)
Article
Multidisciplinary Sciences
Jenni Kesaniemi, Anton Lavrinienko, Eugene Tukalenko, Zbyszek Boratynski, Kati Kivisaari, Tapio Mappes, Gennadi Milinevsky, Anders Pape Moller, Timothy A. Mousseau, Phillip C. Watts
SCIENTIFIC REPORTS
(2019)
Article
Biodiversity Conservation
Anders Pape Moller, Timothy A. Mousseau
ECOLOGICAL INDICATORS
(2019)
Article
Ecology
Tapio Mappes, Zbyszek Boratynski, Kati Kivisaari, Anton Lavrinienko, Gennadi Milinevsky, Timothy A. Mousseau, Anders P. Moller, Eugene Tukalenko, Phillip C. Watts
Article
Ecology
Jenni Kesaniemi, Anton Lavrinienko, Eugene Tukalenko, Ana Filipa Moutinho, Tapio Mappes, Anders Pape Moller, Timothy A. Mousseau, Phillip C. Watts
EVOLUTIONARY ECOLOGY
(2020)
Article
Ecology
Sylvie Arnaise, Jacqui A. Shykoff, Anders P. Moller, Timothy A. Mousseau, Tatiana Giraud
ECOLOGY AND EVOLUTION
(2020)
Review
Plant Sciences
Timothy A. Mousseau, Anders Pape Moller
FRONTIERS IN PLANT SCIENCE
(2020)
Article
Multidisciplinary Sciences
Karine Beaugelin-Seiller, Jacqueline Garnier-Laplace, Claire Della-Vedova, Jean-Michel Metivier, Hugo Lepage, Timothy A. Mousseau, Anders Pape Moller
SCIENTIFIC REPORTS
(2020)
Article
Ecology
Matthew T. Duggan, Melissa F. Groleau, Ethan P. Shealy, Lillian S. Self, Taylor E. Utter, Matthew M. Waller, Bryan C. Hall, Chris G. Stone, Layne L. Anderson, Timothy A. Mousseau
Summary: Utilizing transfer learning, a CNN model was created to efficiently identify and classify species with high accuracy and F1 score using a small dataset. This demonstrates that ideal accuracy can be achieved with fewer images than previously thought necessary.
ECOLOGY AND EVOLUTION
(2021)
Article
Multidisciplinary Sciences
Anton V. Korsakov, Emilia V. Geger, Dmitry G. Lagerev, Leonid I. Pugach, Timothy A. Mousseau
Article
Biochemistry & Molecular Biology
Anders Pape Moller, Karsten Laursen, Filiz Karadas
Article
Biodiversity Conservation
Yongcui Lan, Jinliang Wang, Qianwei Liu, Fang Liu, Lanfang Liu, Jie Li, Mengjia Luo
Summary: This study focuses on the five major plateau lake basins in central Yunnan, China, and constructs an ecological security pattern using the source-resistance surface-corridor-pinch point framework. The study simulates land use/cover change in the region and identifies early warning regions where future urban expansion poses a threat to current ecological source areas and corridors.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Pingping Huang, Feng Zhao, Bailing Zhou, Kuidong Xu
Summary: This study investigates the distribution of benthic microeukaryotes in the China Seas and finds that they can stride over the ecological barrier of 32 degrees N. The study also highlights the significant influence of depth, temperature, and latitude on communities in the China Seas.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Federico Morelli, Yanina Benedetti, Jesse Stanford, Leszek Jerzak, Piotr Tryjanowski, Paolo Perna, Riccardo Santolini
Summary: Species distribution models (SDMs) are numerical tools used for predicting species' spatial distribution. This study found that ecological characteristics, such as habitat specialization, play a role in improving the accuracy of SDMs.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Xiaoxuan Wu, Hang Liu, Wei Liu
Summary: Global climate change, urbanization, and economic development have increased the need for sustainable human development, urban ecological governance, and low-carbon energy transformation. This study analyzes the green ecological transition in Chengdu based on panel data from 2010 to 2020, exploring its spatiotemporal evolution and key factors. The results show an overall upward trend in Chengdu's green ecological development and positive spatial autocorrelation in certain districts.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Castaldi Simona, Formicola Nicola, Mastrocicco Micol, Morales Rodriguez Carmen, Morelli Raffaella, Prodorutti Daniele, Vannini Andrea, Zanzotti Roberto
Summary: Sustainable agricultural practices are increasingly important for global and national environmental policies and economy. This study compared the sustainability of grape production under integrated and organic management using multiple indicators. The results showed that organic management was more beneficial for most environmental aspects of the agroecosystem compared to integrated management, without affecting grape yield.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Gaia Vaglio Laurin, Alexander Cotrina-Sanchez, Luca Belelli-Marchesini, Enrico Tomelleri, Giovanna Battipaglia, Claudia Cocozza, Francesco Niccoli, Jerzy Piotr Kabala, Damiano Gianelle, Loris Vescovo, Luca Da Ros, Riccardo Valentini
Summary: Phenology monitoring is important for understanding forest functioning and climate impacts. This research compares the phenological behavior of European beech forests using Tree-Talker (TT+) and Sentinel 2 satellite data. The study finds differences in the information derived by the two sensor types, particularly in terms of season length, phenology changepoints, and leaf period variability. TT+ with its higher temporal resolution demonstrates precision in capturing the phenological changepoints, especially when satellite image availability is limited.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Huanhuan Pan, Ziqiang Du, Zhitao Wu, Hong Zhang, Keming Ma
Summary: The land use and cover changes resulting from coal mining activities and ecological restoration have had a significant impact on ecosystem services in mining areas. This study investigates the relationship between ecosystem services and land use intensity in coal mining areas, emphasizing the importance of understanding this interdependence for balanced human-land system development. The research examines the evolving relationship across different reclamation stages in Shanxi, China, using a coupling coordination degree model. The findings suggest the need for timely and judicious reclamation of coalfields, considering the land's bearing capacity.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Jingjuan He, Yijun Shi, Lihua Xu, Zhangwei Lu, Mao Feng
Summary: This study examines the spatial interplay between changes in the blue-green spatial distribution and modifications in land surface temperature grades in Shanghai. The findings reveal that the transformation of the blue-green spatial pattern differs between different sectors of the city, and the impact on the thermal environment varies spatially.
ECOLOGICAL INDICATORS
(2024)
Article
Biodiversity Conservation
Yi Xu, Di Zhang, Junqiang Lin, Qidong Peng, Xiaohui Lei, Tiantian Jin, Jia Wang, Ruifang Yuan
Summary: This study analyzed the response relationship between phytoplankton growth and water environmental parameters in the Middle Route of the South-to-North Water Diversion Project in China using long-term monitoring data and machine learning models. The results revealed the differences between monitoring sites and identified the key parameters that affect phytoplankton growth.
ECOLOGICAL INDICATORS
(2024)