Article
Clinical Neurology
Maya Kuperberg, Douglas Katz, Sophie L. A. Greenebaum, Nevita George, Louisa G. Sylvia, Gustavo Kinrys, Astrid Desrosiers, Andrew A. Nierenberg
Summary: This study examined the relationship between psychotic symptoms during bipolar depressive episodes and suicidal ideation among outpatients with bipolar disorder. The results indicated that patients with psychotic symptoms were more likely to report active suicidal thoughts, including specific plans and methods.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Behavioral Sciences
Aida Alvarez, Armand Guardia, Alexandre Gonzalez-Rodriguez, Maria Betriu, Diego Palao, Jose Antonio Monreal, Virginia Soria, Javier Labad
Summary: This study found differences in rates of suicide attempts and completed suicide among individuals with schizophrenia, schizoaffective disorder, delusional disorder, and first-episode psychosis. The rates varied by diagnosis, clinical setting, and geographical region. Northern European countries reported higher rates of completed suicide in studies of schizophrenia and first-episode psychosis.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Psychiatry
Emma M. Parrish, Samantha A. Chalker, Mayra Cano, Raeanne C. Moore, Amy E. Pinkham, Philip D. Harvey, Thomas Joiner, Amy Lieberman, Eric Granholm, Colin A. Depp
Summary: This study used ecological momentary assessment to investigate the relationship between perceived burdensomeness (PB) and thwarted belonginess (TB) with suicidal ideation (SI) in individuals with psychotic disorders. The results showed that burdensomeness varied less within participants compared to belongingness, and participants with SI had higher burdensomeness ratings and lower belongingness ratings. Social context, psychotic symptoms, mood, and SI were all found to be related to these interpersonal suicide-related risk factors.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Psychology, Clinical
Craig Morgan, Paola Dazzan, Julia Lappin, Margaret Heslin, Kim Donoghue, Paul Fearon, Peter B. Jones, Robin M. Murray, Gillian A. Doody, Ulrich Reininghaus
Summary: By analyzing data from the AESOP-10 study, four specific classes of individuals with different symptom trajectories of psychotic disorders were identified, indicating that the current approach to categorizing the course of psychotic disorders may misclassify patients.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Clinical Neurology
Lin Zhang, Ronald W. H. Verwer, Juan Zhao, Inge Huitinga, Paul J. Lucassen, Dick F. Swaab
Summary: This study found different glial alterations in the prefrontal cortex of patients with major depressive disorder, which were associated with suicide behaviors or psychotic features. Certain genes showed differences in expression levels between suicide and psychotic feature patients, providing insights into the pathophysiology of MDD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Tapio Paljarvi, Jari Tiihonen, Markku Lateenvuo, Antti Tanskanen, Seena Fazel, Heidi Taipale
Summary: This study aimed to establish the risk of suicide associated with incident psychotic depression (PD) compared to incident non-psychotic severe depression (NPD). The results showed that PD was associated with a twofold increased risk of suicide compared to NPD, with the highest relative risks for impact-related and suffocation-related suicides. This study revealed some characteristics of PD patients in terms of the severity of suicidal ideation and choice of self-harm methods.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychology, Clinical
R. Cunningham, A. Milner, S. Gibb, V Rijnberg, G. Disney, A. M. Kavanagh
Summary: Through a longitudinal study, it was found that unemployment is significantly associated with suicide and self-harm, even among individuals without prior mental health issues.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Jo-An Occhipinti, Adam Skinner, Frank Iorfino, Kenny Lawson, Julie Sturgess, Warren Burgess, Tracey Davenport, Danica Hudson, Ian Hickie
Summary: Reducing suicidal behavior is a critical public health issue globally, and targeted investments in social determinants and mental health services have been found to provide the best opportunity to address this issue. Systems modeling and simulation offers a robust approach to guiding decision-making and focusing limited health resources effectively.
Article
Multidisciplinary Sciences
Xiuyan Liu, Xiu Wang, Chunsong Wen, Li Wan
Summary: This study established a predictive model using laboratory indexes and clinical factors to improve diagnostic accuracy in the early stage of mental disorders. The decision tree method showed the highest predictive power and provided a reliable basis for future clinical work.
Review
Dentistry, Oral Surgery & Medicine
Greig D. Taylor, Katherine Carr, Helen J. Rogers, Chris R. Vernazza
Summary: This study found a lack of decision analytical models in the field of child oral health, but most of the available models are of high methodological and reporting quality.
Review
Psychiatry
Sara Barbeito, Patricia Vega, Teresa Sanchez-Gutierrez, Juan Antonio Becerra, Ana Gonzalez-Pinto, Ana Calvo
Summary: This study reviewed suicide in adolescents with psychotic disorders, finding a high risk of suicidal behavior in this population. Main factors associated with suicide attempts included depression, distress with psychotic symptoms, fewer negative symptoms at baseline, positive symptoms, and anxiety disorders. Early detection of adolescents with psychosis is crucial in preventing suicidal acts.
SCHIZOPHRENIA RESEARCH
(2021)
Article
Psychiatry
Qiang Wang, Lei Zhang, Jiechun Zhang, Zhihao Ye, Ping Li, Feng Wang, Yili Cao, Shaojun Zhang, Fang Zhou, Zisheng Ai, Nan Zhao
Summary: The burden of personality disorders in China is significant, with common comorbidities in both psychotic and non-psychotic disorders. However, the distribution patterns of PDs differ between the two types of disorders, suggesting the need for specific strategies in psychiatric clinical practice to address these differences.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Clinical Neurology
ZhaoXuan Shang, XiaoE Lang, Jikun Wang, XiangYang Zhang
Summary: This study investigates the relationship between psychotic symptoms and suicide attempts in young first-episode, drug-naive Chinese Han outpatients diagnosed with Major Depressive Disorder (MDD). The prevalence of Psychotic Major Depressive Disorder (PMD) was found to be 8.3% among the enrolled MDD patients. The study assessed 1289 participants using various scales to evaluate the severity of clinical symptoms, and examined thyroid hormone and glucolipid metabolism indicators. The findings indicate that recent suicide attempts were significantly associated with higher HAMA and CGI scores, elevated TSH and TC levels, as well as higher blood pressure.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2023)
Review
Clinical Neurology
Jasper X. M. Wiebenga, Justine Dickhoff, Saskia Y. M. Merelle, Merijn Eikelenboom, Henriette D. Heering, Renske Gilissen, Patricia Van Oppen, Brenda W. J. H. Penninx
Summary: The study highlights the high prevalence of suicide ideation and attempt among individuals with depressive and anxiety disorders, especially those with comorbid conditions. Various determinants such as clinical severity, sleep dysfunctions, aggression, hopelessness, and childhood trauma were found to be associated with suicide ideation and attempt, along with neurobiological factors like immune dysregulation and abnormal brain activity. More research is needed to further explore the multifactorial nature of suicide ideation and attempt, and to improve detection and intervention strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Paola Salvatore, Ross J. Baldessarini, Harimandir K. Khalsa, Mauricio Tohen
Summary: The study analyzed psychopathological details of prodromes leading to first-lifetime psychotic episodes and found that these features could predict and distinguish final diagnoses of MDD, BD-I, and SzAffD. The findings highlight the value of early psychopathology in predicting final diagnoses of major affective and schizoaffective disorders.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Anders Wimo, Ron Handels, Riitta Antikainen, Maria Eriksdotter, Linus Jonsson, Martin Knapp, Jenni Kulmala, Tiina Laatikainen, Jenni Lehtisalo, Markku Peltonen, Anders Skoldunger, Hilkka Soininen, Alina Solomon, Timo Strandberg, Jaakko Tuomilehto, Tiia Ngandu, Miia Kivipelto
Summary: This study estimated the potential cost-effectiveness of the FINGER program in Finland. The results showed that the FINGER program could save costs and improve quality-adjusted life years, supporting its effectiveness in preventing cognitive impairment and disability.
ALZHEIMERS & DEMENTIA
(2023)
Article
Economics
Joan Costa-Font, Martin Knapp, Cristina Vilaplana-Prieto
Summary: This study examines the impact of risk exposure to COVID-19 on the mental wellbeing effect of lockdowns and concludes that lockdown measures no longer reduce mental wellbeing in an environment of high mortality.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Public, Environmental & Occupational Health
Louisa-Kristin Muntendorf, Hans-Helmut Koenig, Luca Janssen, Irina Pokhilenko, Ruben Drost, Judit Simon, Lidia Garcia-Perez, Valentin Brodszky, Leona Hakkaart-van Roijen, A-La Park, Silvia Evers, Alexander Konnopka
Summary: This study aims to incorporate inter-sectoral unit costs of the German Criminal Justice Sector into health economic evaluations from a societal perspective. Through questionnaire surveys and direct correspondence, the unit costs for various sectors, such as police and fire brigade, were calculated. The lack of these costs highlights the importance of this research in health economic evaluations.
GESUNDHEITSOEKONOMIE UND QUALITAETSMANAGEMENT
(2023)
Article
Psychiatry
Niklaus Stulz, Reto Joerg, Constanze Reim-Gautier, Charles Bonsack, Philippe Conus, Sara Evans-Lacko, Kerstin Gabriel-Felleiter, Eva Heim, Matthias Jaeger, Martin Knapp, Dirk Richter, Andres Schneeberger, Sir Graham Thornicroft, Rafael Traber, Simon Wieser, Alexandre Tuch, Urs Hepp
Summary: This study used small area analysis to identify health service areas for psychiatric outpatient care in Switzerland and found significant variation in the utilization of inpatient and outpatient services between these areas.
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
(2023)
Article
Psychology, Developmental
Mauricio Scopel Hoffmann, Sara Evans-Lacko, Stephan Collishaw, Martin Knapp, Andrew Pickles, Christina Shearer, Barbara Maughan
Summary: This study provides evidence on the long-term outcomes of both general and specific dimensions of adolescent psychopathology using parent and teacher reports. The general factors of psychopathology reported by parents and teachers were associated with various outcomes in socioeconomic, relationship, health, personality domains, as well as social exclusion. The specific factors reported by teachers were associated with more outcomes compared to those reported by parents.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Serena Sabatini, Anthony Martyr, Laura D. Gamble, Ian R. Jones, Rachel Collins, Fiona E. Matthews, Martin Knapp, Jeanette M. Thom, Catherine Henderson, Christina Victor, Claire Pentecost, Linda Clare, IDEAL Programme Team
Summary: This study describes the levels of social, cultural, and economic capital among people with dementia and examines the differences in personal characteristics and quality of life over time based on different combinations of capital. The results show that people with dementia have relatively lower levels of social, cultural, and economic capital, although they are not significantly lower compared to older adults in the UK. The study identifies four groups of people with dementia based on their capital levels and finds that higher levels of capital are associated with higher quality of life and well-being. Therefore, efforts from the government and society are needed to address the social, cultural, and economic disadvantages among people with dementia.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Psychiatry
Joseph Botham, Alan Simpson, Paul McCrone
Summary: This study aimed to estimate the costs of care for individuals with a personality disorder diagnosis, and compare service use and costs between those receiving specialist input and those receiving generic care. Service use data was collected from records and costs were calculated. Comparisons were made between individuals receiving care from specialist personality disorder teams and those who did not. Regression modeling identified demographic and clinical factors that predicted costs. Results showed that mean total costs before diagnosis were £10,156 for the specialist group and £11,531 for the non-specialist group. Post-diagnosis costs were £24,017 and £22,266 respectively. Costs were associated with specialist care, comorbid conditions, and living outside of London.
Article
Psychology, Multidisciplinary
Claudia Lotito, Giulia Turrini, Marianna Purgato, Richard A. A. Bryant, Mireia Felez-Nobrega, Josep Maria Haro, Vincent Lorant, David McDaid, Roberto Mediavilla, Maria Melchior, Pablo Nicaise, Michela Nose, A-La Park, Kerry R. R. McGreevy, Rinske Roos, Andrea Tortelli, James Underhill, Julian Vadell Martinez, Anke Witteveen, Marit Sijbrandij, Corrado Barbui
Summary: The COVID-19 pandemic has had significant and potentially long-lasting effects on mental health and wellbeing globally, with vulnerable groups such as migrants, refugees, and asylum seekers being disproportionately affected. This study aimed to identify the priority mental health needs of this population in order to inform the adaptation and implementation of psychological intervention programs.
Article
Health Care Sciences & Services
Paul Hinck, Mencia Gutierrez-Colosia, Christine Duval, Hans-Helmut Konig, Judit Simon, Claudia Fischer, Susanne Mayer, Luis Salvador-Carulla, Valentin Brodszky, Leona Hakkaart-van Roijen, Silvia Evers, A. -La Park, William Hollingworth, Alexander PECUNIA Grp, Alexander Konnopka
Summary: This study aimed to improve the comparability of economic evaluations by identifying internationally relevant health and social care services for mental disorders. After systematic literature reviews and expert surveys, a basic list of 56 services including residential care, daycare, and outpatient care was developed. This will enhance the standardization and international comparability of health economic studies for mental disorders.
BMC HEALTH SERVICES RESEARCH
(2023)
Article
Geriatrics & Gerontology
Maximilian Salcher-Konrad, Cheng Shi, Disha Patel, David McDaid, Claudia Iveth Astudillo-Garcia, Kirsten Bobrow, Jacky Choy, Adelina Comas-Herrera, Andra Fry, Martin Knapp, Dara Kiu Yi Leung, Mariana Lopez-Ortega, Klara Lorenz-Dant, Christine Musyimi, David Ndetei, Tuan Anh Nguyen, Deborah Oliveira, Aditya Putra, Alisha Vara, Gloria Wong, Huseyin Naci, STRiDE Evidence Review Grp
Summary: This study aimed to systematically map the available evidence on dementia interventions in low- and middle-income countries (LMICs) to improve the lives of people with dementia or mild cognitive impairment (MCI) and/or their carers. The study found that the research on interventions for dementia in LMICs is concentrated in a few countries, with a skewed selection of interventions and a high risk of bias.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Article
Psychiatry
Antonio Rojas-Garcia, Christian Dalton-Locke, Luke Sheridan Rains, Ceri Dare, Cedric Ginestet, Una Foye, Kathleen Kelly, Sabine Landau, Chris Lynch, Paul Mccrone, Shilpa Nairi, Karen Newbigging, Patrick Nyikavaranda, David Osborn, Karen Persaud, Nick Sevdalis, Martin Stefan, Ruth Stuart, Alan Simpson, Sonia Johnson, Brynmor Lloyd-Evans
Summary: This study aims to develop a typology of mental health crisis care systems and explore the relationship between crisis care service models and psychiatric hospital admissions and detentions.
Article
Psychiatry
Anne M. de Graaff, Pim Cuijpers, Jos W. R. Twisk, Barbara Kieft, Sam Hunaidy, Mariam Elsawy, Noer Gorgis, Theo K. Bouman, Miriam J. J. Lommen, Ceren Acarturk, Richard Bryant, Sebastian Burchert, Katie S. Dawson, Daniela C. Fuhr, Pernille Hansen, Mark Jordans, Christine Knaevelsrud, David McDaid, Naser Morina, Hanspeter Moergeli, A-La Park, Bayard Roberts, Peter Ventevogel, Nana Wiedemann, Aniek Woodward, Marit Sijbrandij
Summary: This study examines the effectiveness of a peer-provided psychological intervention (PM+) in reducing symptoms of common mental disorders (CMDs) among Syrian refugees in the Netherlands. The findings suggest that PM+ has positive effects on reducing symptoms of depression/anxiety, depression, anxiety, PTSD symptoms, and self-identified problems among Syrian refugees, but its effectiveness in improving functional impairment is not significant.
Article
Psychiatry
Roberto Mediavilla, Mireia Felez-Nobrega, Kerry R. McGreevy, Anna Monistrol-Mula, Maria-Fe Bravo-Ortiz, Carmen Bayon, Iago Gine-Vazquez, Rut Villaescusa, Ainoa Munoz-Sanjose, Salvatore Aguilar-Ortiz, Natasha Figueiredo, Pablo Nicaise, A-La Park, Papoula Petri-Romao, Marianna Purgato, Anke B. Witteveen, James Underhill, Corrado Barbui, Richard Bryant, Raffael Kalisch, Vincent Lorant, David McDaid, Maria Melchior, Marit Sijbrandij, Josep Maria Haro, Jose Luis Ayuso-Mateos
Summary: This study evaluated the effectiveness of a mental health intervention in reducing anxiety and depression symptoms among healthcare workers in crisis settings. The results showed that the intervention significantly reduced anxiety and depression symptoms among healthcare workers.
Article
Public, Environmental & Occupational Health
Marianna Purgato, Giulia Turrini, Federico Tedeschi, Riccardo Serra, Lorenzo Tarsitani, Beatrice Compri, Giulia Muriago, Camilla Cadorin, Giovanni Ostuzzi, Pablo Nicaise, Vincent Lorant, Marit Sijbrandij, Anke B. B. Witteveen, Jose Luis Ayuso-Mateos, Roberto Mediavilla, Josep Maria Haro, Mireia Felez-Nobrega, Natasha Figueiredo, Giulia Pollice, David McDaid, A-La Park, Raffael Kalisch, Papoula Petri-Romao, James Underhill, Richard A. A. Bryant, Michela Nose, Corrado Barbui
Summary: This study aims to assess the effectiveness and cost-effectiveness of a psychological intervention program tailored for migrant populations. Participants will be randomized into two groups, one receiving usual care and the other receiving a self-help stress management guide and a cognitive behavioral intervention. The study will evaluate the program's impact on anxiety and depression symptoms, as well as other mental health indicators and cost-effectiveness. This study is important for improving the mental health and wellbeing of migrant populations.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Psychiatry
Maria A. Mendez, Bethany Oakley, Roberto Canitano, Antonia San Jose-Caceres, Michela Tinelli, Martin Knapp, James Cusack, Mara Parellada, Pierre Violland, Jan R. Derk Plas, Ricardo Canal-Bedia, Alvaro Bejarano-Martin, Declan G. M. Murphy, Vinciane Quoidbach, Celso Arango
Summary: There is a lack of harmonized guidelines in Europe for early detection, diagnosis, and intervention for autism, leading to unsatisfactory experiences for autistic individuals and their caregivers. The analysis of care pathways in Italy, Spain, and the UK revealed long wait times for screening and diagnosis, limited information and support, and deficient family support throughout the journey.
EUROPEAN PSYCHIATRY
(2023)
