期刊
EARLY HUMAN DEVELOPMENT
卷 85, 期 10, 页码 611-615出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.earlhumdev.2009.09.010
关键词
Meconium; Amniotic fluid; Meconium aspiration syndrome; Post-dates pregnancy; Labour induction; Misoprostol; Amnioinfusion; Randomized trials
Background: Meconium-stained amniotic fluid is a common occurrence which places the mother at risk of escalating obstetric interventions, and the baby at risk of meconium aspiration syndrome. Methods: The Cochrane Library was searched for interventions related to care before delivery with useful evidence on the outcomes 'meconium-stained amniotic fluid' and 'meconium aspiration syndrome'. Findings: Curtailment of post-term pregnancy reduces the occurrence of meconium-stained amniotic fluid, and meconium aspiration syndrome. Uterine stimulants, particularly misoprostol, are associated with occurrence of meconium-stained amniotic fluid. Amniotomy during labour may be a risk factor for meconium aspiration syndrome. There is little research evidence on the benefits or otherwise of obstetric interventions such as expedited delivery for meconium-stained liquor without other evidence of fetal distress. Amnioinfusion for meconium-stained amniotic fluid improves neonatal outcome only in settings with limited peripartum, surveillance. There is insufficient evidence to support the use of amnioinfusion for meconium-stained liquor in settings with adequate peripartum surveillance. (C) 2009 Elsevier Ireland Ltd. All rights reserved
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