期刊
E-JOURNAL OF CHEMISTRY
卷 7, 期 -, 页码 S458-S464出版社
WWW PUBL PTE
DOI: 10.1155/2010/195725
关键词
1,2,4-Triazole-3-thione; Schiff bases; Antimicrobial activity
A series of Schiff bases (4a-j) were prepared by reacting 4-amino-5-(1-phenylethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione and substituted aromatic aldehydes. The chemical structures were confirmed by means of UV, (1)H NMR, IR, MS(API-ES) spectral data and elemental analysis. All the synthesized compounds were screened for their antimicrobial activity. Among the tested compounds, Schiff bases with 4-OH and 4-NO(2) substituent exhibited remarkable antimicrobial activity against all the tested microorganism.
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