Article
Audiology & Speech-Language Pathology
Hedvig Eriksson, Lisa Tuomi, Caterina Finizia
Summary: This study aimed to investigate whether patients with dysphagia after treatment for head and neck cancer can improve their vocal function through head lift exercises (Shaker's exercise). The study found that patients in the intervention group had less roughness and vocal fry in their voices at follow-up compared to the control group. However, there were no statistically significant changes in the intervention or control group regarding GRBAS, VF, or VHI. Therefore, this study only provides cautious support for the use of head lift exercise in improving the voice of patients with dysphagia after treatment for head and neck cancer.
Article
Otorhinolaryngology
Sara Fredslund Hajdu, Irene Wessel, Susanne Oksbjerg Dalton, Signe Janum Eskildsen, Christoffer Johansen
Summary: The study investigated the effects of swallowing exercises and progressive resistance training on patients with head and neck cancer undergoing radiotherapy. Results showed significant improvements in mouth opening, quality of life, depression, and anxiety in the intervention group compared to non-active controls at 12 months follow-up.
Article
Otorhinolaryngology
Kerstin Petersson, Caterina Finizia, Lisa Tuomi
Summary: The study aimed to investigate predictors of severe dysphagia in head and neck cancer patients post-radiotherapy. Tumor of the tonsil, overweight at time of videofluoroscopy and each unit increase in Body Mass Index (BMI) were found to be associated with lower risk of severe dysphagia. Long-term feeding tube use and significant weight loss were identified as risk factors for severe dysphagia.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2021)
Article
Rehabilitation
Karen B. Ng, Richard D. Jones, Esther Guiu Hernandez, Phoebe Macrae, Maggie-Lee Huckabee
Summary: This study aimed to identify and characterize subgroups of stroke patients with clinical signs of dysphagia based on swallowing-related strength and skill impairments of the submental muscle group. The research found several subgroups within stroke patients in terms of swallowing function, while healthy and myopathic participants demonstrated predominantly homogeneous swallowing patterns. Skill assessment in swallowing may play a more predictive role in classification of swallowing function.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Otorhinolaryngology
Margot Baudelet, Frederic Duprez, Leen Van den Steen, Sandra Nuyts, Daan Nevens, Ann Goeleven, Caroline Vandenbruaene, Hanne Massonet, Alice Vergauwen, Heleen Bollen, Sarah Deschuymer, Kristien Wouters, Marc Peeters, Carl Van Laer, Steven Marien, Michiel Van den Brekel, Lisette van der Molen, Tom Vauterin, Joost van Dinther, Hilde Verstraete, Isabel Hutsebaut, Sabine Meersschout, Olivier Vanderveken, Marc De Bodt, Gwen Van Nuffelen
Summary: This multicenter RCT investigated the effect of three different service-delivery modes on patients' adherence to prophylactic swallowing exercises during radiotherapy. The study found that adherence decreased over time in all groups, but the therapist-supported group achieved the highest adherence rates. Increasing face-to-face contact with a speech-language therapist can overcome the problem of low adherence in this population.
Review
Medicine, General & Internal
Yi-Hsiang Chiu, Wen-Hsuan Tseng, Jenq-Yuh Ko, Tyng-Guey Wang
Summary: Swallowing dysfunction is a common issue for head and neck cancer patients after radiotherapy, which can be improved through rehabilitation therapy and feeding tube placement.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2022)
Article
Medicine, Research & Experimental
Michelle Florie, Walmari Pilz, Bernd Kremer, Femke Verhees, Ghislaine Waltman, Bjorn Winkens, Naomi Winter, Laura Baijens
Summary: This study found a relationship between patient-reported symptoms of oropharyngeal dysphagia using the EAT-10 questionnaire and swallowing function in HNC patients. The EAT-10 score was indicative of postswallow pharyngeal residue, particularly in the vallecular and pyriform sinus areas. A cutoff point of 19 points was useful for detecting pharyngeal residue in this population.
Article
Clinical Neurology
Mahmut Sevim, Numan Demir, Aynur Ayse Karaduman, Selen Serel-Arslan
Summary: The study aimed to examine the relationship between dysphagia severity and head and neck proprioception in patients with neurological diseases. Results showed a moderate, positive correlation between dysphagia severity and neck proprioception, suggesting that decreased head and neck proprioception may be related to severe dysphagia. The findings highlight the importance of considering head and neck proprioception in dysphagia management.
NEUROLOGICAL SCIENCES
(2022)
Article
Otorhinolaryngology
Aydan Bastug Dumbak, Fatma Esen Aydinli, Gozde Yazici, Onal Incebay, Zehra Yildiz, Deniz Yuce, Nilda Suslu, Oguz Kuscu, Mavis Emel Kulak Kayikci
Summary: The objective of this study is to investigate the dose-effect relationship between chewing and swallowing functions in patients undergoing intensity-modulated radiotherapy (IMRT) for head and neck cancers. The results suggest that IMRT treatment leads to impairment of swallowing functions and the occurrence of side effects. The study also identifies dose limits associated with toxicity.
Review
Audiology & Speech-Language Pathology
Dai Pu, Theresa Jingyun Yao
Summary: Swallowing function can be impaired due to medical conditions or age-related factors. This review found that incorporating whole-body exercises as part of a comprehensive program seems to have more beneficial effects on swallowing function than traditional swallowing exercises alone. Future research should explore how whole-body exercises can be used in different populations to influence swallowing function.
INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS
(2023)
Article
Rehabilitation
Nayeon Ko, Hyun Haeng Lee, Min Kyun Sohn, Deog Young Kim, Yong-Il Shin, Gyung-Jae Oh, Yang-Soo Lee, Min Cheol Joo, So Young Lee, Min-Keun Song, Junhee Han, Jeonghoon Ahn, Young-Hoon Lee, Won Hyuk Chang, Soo Mi Choi, Seon Kui Lee, Jongmin Lee, Yun-Hee Kim
Summary: The study identified that the incidence of dysphagia after ischemic stroke was 32.3%. Predictive factors for the presence of dysphagia included age, low BMI, premorbid disabilities, brainstem lesions, and NIHSS.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Medicine, General & Internal
Jin-Woo Park, Chi-Hoon Oh, Bo-Un Choi, Ho-Jin Hong, Joong-Hee Park, Tae-Yeon Kim, Yong-Jin Cho
Summary: This study compared the effects of two different tongue-strengthening exercises on the swallowing function in older adults, finding that regardless of the method used, tongue-strengthening exercises significantly improved lingual strength and swallowing function in the elderly.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Otorhinolaryngology
Jacinda Choy, Fereshteh Pourkazemi, Caitlin Anderson, Hans Bogaardt
Summary: This study conducted a systematic review to investigate the dosages of swallowing exercises reported in intervention studies on post-stroke dysphagia. The results revealed inconsistent reporting and significant variations in the dosages of swallowing exercises, emphasizing the importance of consistent and comprehensive dosage reporting in dysphagia research.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Otorhinolaryngology
Claire Jeans, Bena Brown, Elizabeth C. Ward, Anne E. Vertigan, Amanda E. Pigott, Jodie L. Nixon, Chris Wratten, May Boggess
Summary: This study examined the development trajectory of external and internal head and neck lymphoedema (HNL) in patients with head and neck cancer (HNC) up to 12 months post-chemoradiotherapy (CRT), as well as the relationship between HNL and swallowing function. The findings showed that external HNL largely resolved by 12 months post-CRT, while internal HNL persisted. Patients with higher severity of external and/or internal HNL and more diffuse internal HNL were expected to have more severe dysphagia.
Review
Rehabilitation
Irene Battel, Irene Calvo, Margaret Walshe
Summary: The use of biofeedback in the treatment of dysphagia in patients with PD shows potential positive effects on swallowing-related quality of life. However, existing studies have low methodological quality and high risk of bias, future research should be rigorously designed to determine the optimal types, schedules, and timing of biofeedback treatment.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Otorhinolaryngology
Rebecca T. Karsten, Leon C. ter Beek, Bas Jasperse, Maarten J. A. van Alphen, Johannes M. Peeters, Lisette van der Molen, Frans J. M. Hilgers, Martijn M. Stuiver, Ludi E. Smeele
Summary: This study investigated the importance of swallowing muscle strength exercises and the muscles activated when using a swallow exercise aid (SEA). Through comparison using MRI scans, it was determined that SEA exercises mainly activate the suprahyoid, infrahyoid, sternocleidomastoid, and lateral pterygoid muscle groups, highlighting their potential for improving swallowing rehabilitation.
Article
Hematology
Marie Jose Kersten, Julia Driessen, Josee M. Zijlstra, Wouter J. Plattel, Franck Morschhauser, Pieternella J. Lugtenburg, Pauline Brice, Martin Hutchings, Thomas Gastinne, Roberto Liu, Coreline N. Burggraaff, Marcel Nijland, Sanne H. Tonino, Anne I. J. Arens, Roelf Valkema, Harm van Tinteren, Marta Lopez-Yurda, Arjan Diepstra, Daphne De Jong, Anton Hagenbeek
Article
Otorhinolaryngology
Klaske E. van Sluis, Rob J. J. H. van Son, Lisette van der Molen, Anthony John MCGuinness, Carsten E. Palme, Daniel Novakovic, Danielle Stone, Lydia Natsis, Emma Charters, Kelly Jones, Richard Dirven, Michiel W. M. van den Brekel
Summary: The study aimed to evaluate voice outcomes from pre- up to 12 months post total laryngectomy. Most participants achieved successful TE-speech, while some relied on alternative communication methods. Patient-reported outcomes indicated acceptance of the condition and sufficient coping in the long term, although acoustic rated voice quality remained abnormal at all post-surgery time-points.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Rebecca T. Karsten, Najiba Chargi, Lisette van der Molen, Rob J. J. H. van Son, Remco de Bree, Abrahim Al-Mamgani, Jan P. de Boer, Frans J. M. Hilgers, Michiel W. M. van den Brekel, Ludi E. Smeele, Martijn M. Stuiver
Summary: The study aimed to evaluate swallowing, mouth opening and speech function of patients with stage III-IV oropharyngeal carcinoma (OPC) during the first year after radiation-based treatment (RT(+)) with the introduction of a dedicated preventive rehabilitation program. Results show that functional outcomes deteriorated until 6 months post-treatment, improved by 12 months but did not return to baseline levels, with a significant proportion of patients still experiencing dysphagia, trismus and speech problems. Despite successful implementation, there is room for improvement in the current rehabilitation program, with pretreatment sarcopenia identified as a potential target for rehabilitation strategies.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Oncology
Anna C. Nuijens, Arlene L. Oei, Bregje van Oorschot, Jorrit Visser, Rob M. van Os, Perry D. Moerland, Nicolaas A. P. Franken, Coen R. N. Rasch, Lukas J. A. Stalpers
Summary: This study investigated the contribution of genetic predisposition and dose-volume factors to late radiation toxicity in cancer patients treated with highly conformal radiation therapy. The results suggest that impaired DNA double-strand break repair is the critical determining factor of late radiation toxicity.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2022)
Article
Oncology
Anouk Steur, Paulien A. M. A. Raymakers-Janssen, Martin C. J. Kneyber, Sandra Dijkstra, Job B. M. van Woensel, Dick A. van Waardenburg, Cornelis P. van de Ven, Alida F. W. van der Steeg, Marc Wijnen, Marc R. Lilien, Ronald R. de Krijger, Harm van Tinteren, Annemieke S. Littooij, Geert O. Janssens, Annemarie M. L. Peek, Godelieve A. M. Tytgat, Annelies M. Mavinkurve-Groothuis, Martine van Grotel, Marry M. van den Heuvel-eibrink, Roelie M. Woesten-van Asperen
Summary: This retrospective study assessed the frequency, clinical characteristics, and outcomes of children with Wilms tumor requiring treatment at the PICU in the Netherlands. Younger age at diagnosis, intensive chemotherapy regimens, and bilateral tumor surgery were risk factors for unplanned PICU admissions. Hypertension and renal dysfunction were frequently observed in these patients during follow-up.
Article
Otorhinolaryngology
Anne N. Heirman, Vincent van der Noort, Rob van Son, Japke F. Petersen, Lisette van der Molen, Gyorgy B. Halmos, Richard Dirven, Michiel W. M. van den Brekel
Summary: Objective voice prosthesis leakage significantly affects the quality of life of laryngectomy patients. However, the concept of prophylactic voice prosthesis replacement was found to be unfeasible due to high inter- and intrapatient variability in device lifetime.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Otorhinolaryngology
Margot Baudelet, Frederic Duprez, Leen Van den Steen, Sandra Nuyts, Daan Nevens, Ann Goeleven, Caroline Vandenbruaene, Hanne Massonet, Alice Vergauwen, Heleen Bollen, Sarah Deschuymer, Kristien Wouters, Marc Peeters, Carl Van Laer, Steven Marien, Michiel Van den Brekel, Lisette van der Molen, Tom Vauterin, Joost van Dinther, Hilde Verstraete, Isabel Hutsebaut, Sabine Meersschout, Olivier Vanderveken, Marc De Bodt, Gwen Van Nuffelen
Summary: This multicenter RCT investigated the effect of three different service-delivery modes on patients' adherence to prophylactic swallowing exercises during radiotherapy. The study found that adherence decreased over time in all groups, but the therapist-supported group achieved the highest adherence rates. Increasing face-to-face contact with a speech-language therapist can overcome the problem of low adherence in this population.
Article
Medicine, Research & Experimental
Hanne Massonet, Ann Goeleven, Leen Van den Steen, Alice Vergauwen, Margot Baudelet, Gilles Van Haesendonck, Olivier Vanderveken, Heleen Bollen, Lisette van der Molen, Frederic Duprez, Peter Tomassen, Sandra Nuyts, Gwen Van Nuffelen
Summary: This multicenter randomized trial aims to compare the efficacy and possible detraining effects of different treatments in 105 C-RAD patients. It will provide new insights into the rehabilitation of C-RAD and optimizing swallowing function.
Article
Audiology & Speech-Language Pathology
Klaske E. van Sluis, Ellen Passchier, Rob J. J. H. van Son, Lisette van der Molen, Martijn Stuiver, Michiel W. M. van den Brekel, Leen Van den Steen, Johanna G. Kalf, Gwen van Nuffelen
Summary: The Dutch translation of the CPIB short form has been validated as a reliable tool for assessing communicative participation in adults with speech problems resulting from a neurological etiology or head and neck cancer. This tool can be used in clinical practice and research to systematically investigate the impact of speech problems on communicative participation in the Dutch-speaking population.
INTERNATIONAL JOURNAL OF LANGUAGE & COMMUNICATION DISORDERS
(2023)
Article
Cardiac & Cardiovascular Systems
Martijn H. van der Ree, Edith M. T. Dieleman, Jorrit Visser, R. Nils Planken, S. Matthijs Boekholdt, Rianne H. A. de Bruin-Bon, Coen R. N. Rasch, Wiert F. Hoeksema, Rianne M. A. J. de Jong, Michiel J. B. Kemme, Jippe C. Balt, Arthur A. M. Wilde, Brian Balgobind, Pieter G. Postema
Summary: This study aims to evaluate the efficacy and safety of Stereotactic Arrhythmia Radiotherapy (STAR). It found that STAR can reduce the number of treated ventricular tachycardia episodes by more than 50% in 67% of patients with therapy-refractory VT. No decrease in cardiac and pulmonary function or treatment-related serious adverse events were observed during follow-up.
Review
Otorhinolaryngology
Coralie R. Arends, Josephine E. Lindhout, Lisette van der Molen, Erica A. Wilthagen, Michiel W. M. van den Brekel, Martijn M. Stuiver
Summary: This systematic review aimed to assess the validity and reliability of measurement instruments for head and neck lymphedema. Eight studies were included, and the Patterson scale and the patient reported LIDS-H&N showed good validity and reliability. However, there is a lack of reliable instruments for measuring external lymphedema in the head and neck region.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Oncology
Myrthe A. D. Buser, Alida F. W. van der Steeg, Marc H. W. A. Wijnen, Matthijs Fitski, Harm van Tinteren, Marry M. M. van den Heuvel-Eibrink, Annemieke S. Littooij, Bas H. M. van der Velden
Summary: Wilms tumor, a common pediatric solid tumor, requires accurate tumor volume measurements to evaluate response to chemotherapy and to determine the feasibility of nephron-sparing surgery. Manual segmentation-based measurements are time-consuming and dependent on the user, while radiological measurements underestimate tumor volume. This study explores the use of deep learning to automate segmentation and improve volume measurements.
Review
Oncology
Buket Kinaci-Tas, Tanja Alderliesten, Frank D. Verbraak, Coen R. N. Rasch
Summary: Retinopathy and optic neuropathy are common and severe ocular complications in patients undergoing radiation therapy for brain, head, and neck cancer. However, there is limited knowledge about the prevalence and dose-response relationship of these complications. Further research is needed to improve the precision of radiation therapy.
Article
Oncology
Franciscus A. Diepstraten, Jan Wiersma, Reineke A. Schoot, Rutger R. G. Knops, Charlotte L. Zuur, Annelot J. M. Meijer, Raquel Davila Fajardo, Bradley R. Pieters, Brian V. Balgobind, Henrike Westerveld, Nicole Freling, Harm van Tinteren, Ludwig E. Smeele, Arjan Bel, Marry M. van den Heuvel-eibrink, Robert J. Stokroos, Johannes H. M. Merks, Alexander E. Hoetink, Marinka L. F. Hol
Summary: This study investigated the frequency and patterns of hearing loss (HL) in survivors of head and neck rhabdomyosarcoma (HNRMS) and explored the dose-effect relationship between radiotherapy dose to the cochlea and HL. The results showed that up to 19% of HNRMS survivors experienced HL. Furthermore, a significant association was found between the maximum cochlear irradiation dose and HL (>= Muenster 2b). More research is needed to further understand the patterns of HL in HNRMS survivors and the relationship between radiotherapy dose and HL.