Article
Medicine, Research & Experimental
Qiao Wang, Xiaojun Ding, De Huai, Weibing Zhao, Jun Wang, Chenglan Xie
Summary: Systemic lidocaine infusion during upper airway surgery can improve postoperative early recovery quality, reduce intraoperative opioid dosage, decrease postoperative nausea and vomiting, and lower postoperative 48-hour pain ratings. The study indicates a positive impact of lidocaine on postoperative recovery for patients undergoing upper airway surgery.
Article
Chemistry, Medicinal
Jing Sun, Shan Wang, Jun Wang, Xiuxiu Gao, Guanglei Wang
Summary: This study aimed to compare the effect of intravenous infusion of lidocaine with ultrasound-guided transverse abdominal plane (TAP) block on postoperative recovery and analgesia in patients undergoing bariatric surgery. The results showed that both lidocaine infusion and TAP block provided good postoperative recovery and analgesia, but lidocaine infusion had better analgesic effect at 12 hours and 24 hours postoperatively compared with TAP block.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Surgery
Chamaidi Sarakatsianou, Konstantinos Perivoliotis, Ioannis Baloyiannis, Stavroula Georgopoulou, Aikaterini Tsiaka, George Tzovaras
Summary: The purpose of this study was to evaluate the impact of intraoperative intravenous lidocaine infusion on postoperative opioid consumption after laparoscopic cholecystectomy. A total of 98 patients scheduled for elective laparoscopic cholecystectomy were included and randomized. The study found that lidocaine did not reduce postoperative opioid consumption and had no effect on postoperative pain scores, incidence of shoulder pain, sedation levels, and nausea rates.
LANGENBECKS ARCHIVES OF SURGERY
(2023)
Review
Anesthesiology
Ana Licina, Andrew Silvers
Summary: Perioperative intravenous lidocaine infusion effectively reduces pain, decreases opioid consumption, and shortens hospital stay for patients undergoing spinal surgery. The treatment is more significant in adult patients, with positive effects also seen in pediatric patients.
Article
Anesthesiology
Fabian D. Casas-Arroyave, Susana C. Osorno-Upegui, Mario A. Zamudio-Burbano
Summary: The study compared the analgesic efficacy of intravenous lidocaine with thoracic epidural analgesia using bupivacaine in patients undergoing major abdominal surgery. The results showed that intravenous lidocaine was noninferior to thoracic epidural analgesia for acute postoperative pain control at 24 h postoperatively.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Anesthesiology
Fabian D. Casas-Arroyave, Susana C. Osorno-Upegui, Mario A. Zamudio-Burbano
Summary: This study compared the analgesic efficacy of intravenous lidocaine with thoracic epidural analgesia in patients undergoing major abdominal surgery. The results showed that intravenous lidocaine is noninferior to thoracic epidural analgesia for acute postoperative pain control at 24 hours postoperatively.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Article
Oncology
Ana Tejedor, Lana Bijelic, Mauricio Polanco, Elisenda Pujol
Summary: Intravenous lidocaine infusion may be a safe and effective analgesic approach in cytoreductive surgery (CRS) and is associated with a significant reduction of opioid use and postoperative nausea and vomiting (PONV) compared to opioid-containing thoracic epidural anesthesia (TEA).
Article
Anesthesiology
Kubra Kutay Yazici, Mensure Kaya, Busra Aksu, Suheyla Unver
Summary: This study investigated the effects of perioperative systemic lidocaine infusion on pain control after major gynecologic oncology surgery. Results showed that lidocaine infusion was as effective as epidural analgesia, with better outcomes in terms of time to first flatus and nausea-vomiting incidence.
CLINICAL JOURNAL OF PAIN
(2021)
Article
Medicine, General & Internal
Marion Trouillard, William Dupuis, Helene Siaudeau, Florian Denou, Emmanuelle Longeau, Maxime Leger, Myriam Ammi, Cyril Sargentini, Sigismond Lasocki, Emmanuel Rineau
Summary: Various regional anesthesia techniques have been shown to reduce pain after lung surgery, but controversy remains regarding the best technique. In this study, a strategy combining erector spinae plane block (ESP) for video-assisted thoracic surgery (VATS) and thoracic epidural analgesia (TEA), or intrathecal analgesia (IA) for thoracotomy, was found to provide effective analgesia after lung resection. Interestingly, IA appeared to be more effective than TEA in reducing length of hospital stay and pain on Day 0 and 3.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Anesthesiology
Seon Ju Kim, Yong Seon Choi, Yong Min Chun, Hye Jin Kim, Chunggu Han, Seokyung Shin
Summary: Intravenous lidocaine may be helpful in reducing opioid requirements during the acute postoperative period in patients undergoing arthroscopic rotator cuff repair. It may be a viable option for multimodal analgesia in ARCR when regional analgesia is not possible.
CLINICAL JOURNAL OF PAIN
(2022)
Article
Medicine, Research & Experimental
Hugh M. Paterson, Seonaidh Cotton, John Norrie, Susan Nimmo, Irwin Foo, Angie Balfour, Doug Speake, Graeme MacLennan, Andrew Stoddart, Karen Innes, Sarah Cameron, Lorna Aucott, Kirsty McCormack
Summary: The ALLEGRO trial aims to assess the effectiveness of perioperative intravenous lidocaine in improving return of GI function after minimally invasive colorectal surgery. The study suggests that IV lidocaine can accelerate the recovery of GI function, reduce the rate of postoperative ileus, shorten hospital stay, alleviate pain and discomfort, and lead to faster recovery and discharge from hospital, resulting in significant cost savings for the National Health Service (NHS).
Review
Anesthesiology
Katrina Pirie, Emily Traer, Damien Finniss, Paul S. Myles, Bernhard Riedel
Summary: Poorly controlled postoperative pain is associated with negative effects on patients' quality of life and functional recovery, including the risk of persistent pain and long-term opioid use. Alternative, opioid-minimising, multimodal analgesic strategies are needed in order to address opioid-related side-effects and the opioid abuse epidemic. Limited research exists on patient recovery quality after intraabdominal surgery using specific analgesic techniques.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Clinical Neurology
Yan Xu, Mao Ye, Ying Hong, Yi Kang, Yue Li, Xiao Xiao, Li Zhou, Chunling Jiang
Summary: This prospective trial aims to investigate the efficacy of intraoperative and 72 postoperative hours intravenous lidocaine on postoperative pain and recovery after hepatectomy, providing a new strategy for perioperative pain management for hepatectomy.
JOURNAL OF PAIN RESEARCH
(2021)
Article
Surgery
Qingfeng Wei, Ming Xia, Qin Zhang, Zhiping Wang
Summary: The study found that continuous intravenous pumping of lidocaine during the perioperative period has little effect on immune function in breast cancer patients and promotes postoperative recovery.
Review
Medicine, Research & Experimental
Chenglan Xie, Qiao Wang, De Huai
Summary: OSA is characterized by intermittent and recurrent obstruction of the upper airway during sleep, with hypoxia/reoxygenation being the main pathophysiological mechanism. IV lidocaine infusion has anti-inflammatory, antihyperalgesic, and analgesic properties, reducing postoperative pain and cardiovascular responses.
MEDICAL SCIENCE MONITOR
(2021)
