Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3-diisopropylurea
出版年份 2013 全文链接
标题
Experimental design for the optimization and robustness testing of a liquid chromatography tandem mass spectrometry method for the trace analysis of the potentially genotoxic 1,3-diisopropylurea
作者
关键词
-
出版物
Drug Testing and Analysis
Volume 6, Issue 9, Pages 898-908
出版商
Wiley
发表日期
2013-11-16
DOI
10.1002/dta.1583
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Rational design of core–shell molecularly imprinted polymer based on computational simulation and Doehlert experimental optimization: application to the separation of tanshinone IIA from Salvia miltiorrhiza Bunge
- (2012) Xianjun Jia et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Strategy for Optimizing LC-MS Data Processing in Metabolomics: A Design of Experiments Approach
- (2012) Mattias Eliasson et al. ANALYTICAL CHEMISTRY
- Environmental and economic analysis for selection and engineering sustainable API degenotoxification processes
- (2012) György Székely et al. GREEN CHEMISTRY
- Removal of potentially genotoxic acetamide and arylsulfonate impurities from crude drugs by molecular imprinting
- (2012) György Székely et al. JOURNAL OF CHROMATOGRAPHY A
- Application of design of experiments and design space methodology for the HPLC-UV separation optimization of aporphine alkaloids from leaves of Spirospermum penduliflorum Thouars
- (2012) Mamy H. Rafamantanana et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Design of experiments as a tool for LC–MS/MS method development for the trace analysis of the potentially genotoxic 4-dimethylaminopyridine impurity in glucocorticoids
- (2012) Gy. Székely et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Application of quality by design elements for the development and optimization of an analytical method for protamine sulfate
- (2012) David Awotwe-Otoo et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Development and validation of RP-UPLC method for the determination of darifenacin hydrobromide, its related compounds and its degradation products using design of experiments
- (2012) M. Vishnu Murthy et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography
- (2011) Benjamin Debrus et al. ANALYTICA CHIMICA ACTA
- A new approach for generic screening and quantitation of potential genotoxic alkylation compounds by pre-column derivatization and LC-MS/MS analysis
- (2011) A. M. van Wijk et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Optimal experimental designs in RPLC at variable solvent content and pH based on prediction error surfaces
- (2011) J. R. Torres-Lapasió et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Overall impact of the regulatory requirements for genotoxic impurities on the drug development process
- (2011) Antonio Giordani et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments, independent component analysis and design space
- (2011) B. Debrus et al. JOURNAL OF CHROMATOGRAPHY A
- Organic solvent nanofiltration: A platform for removal of genotoxins from active pharmaceutical ingredients
- (2011) György Székely et al. JOURNAL OF MEMBRANE SCIENCE
- Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate
- (2011) Antonia García et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Global optimization of the infrared matrix-assisted laser desorption electrospray ionization (IR MALDESI) source for mass spectrometry using statistical design of experiments
- (2011) Jeremy A. Barry et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- A hybrid approach to reach stringent low genotoxic impurity contents in active pharmaceutical ingredients: Combining molecularly imprinted polymers and organic solvent nanofiltration for removal of 1,3-diisopropylurea
- (2011) György Székely et al. SEPARATION AND PURIFICATION TECHNOLOGY
- Design, preparation and characterization of novel molecularly imprinted polymers for removal of potentially genotoxic 1,3-diisopropylurea from API solutions
- (2011) György Székely et al. SEPARATION AND PURIFICATION TECHNOLOGY
- Minimisation of instrumental noise in the acquisition of FT-NIR spectra of bread wheat using experimental design and signal processing techniques
- (2010) G. Foca et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Strategies for the identification, control and determination of genotoxic impurities in drug substances: A pharmaceutical industry perspective
- (2010) N.V.V.S.S. Raman et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Development of Quality-By-Design Analytical Methods
- (2010) Frederick G. Vogt et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Reichardt's dye and its reactions with the alkylating agents 4-chloro-1-butanol, ethyl methanesulfonate, 1-bromobutane and Fast Red B - a potentially useful reagent for the detection of genotoxic impurities in pharmaceuticals
- (2010) Damion K. Corrigan et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- A Systematic Method Development Strategy for Determination of Pharmaceutical Genotoxic Impurities
- (2010) Mingjiang Sun et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Removal of Electrophilic Potential Genotoxic Impurities Using Nucleophilic Reactive Resins
- (2010) Claire Lee et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Analysis of potential genotoxic impurities in pharmaceuticals by two-dimensional gas chromatography with Deans switching and independent column temperature control using a low-thermal-mass oven module
- (2009) Frank David et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Confocal Raman microscopy to probe content uniformity of a lipid based powder for inhalation: A quality by design approach
- (2009) Carina Schoenherr et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Rapid high performance liquid chromatography method development with high prediction accuracy, using 5cm long narrow bore columns packed with sub-2μm particles and Design Space computer modeling
- (2009) Szabolcs Fekete et al. JOURNAL OF CHROMATOGRAPHY A
- Enhancing the detection sensitivity of trace analysis of pharmaceutical genotoxic impurities by chemical derivatization and coordination ion spray-mass spectrometry
- (2009) Lin Bai et al. JOURNAL OF CHROMATOGRAPHY A
- Determination of low ppm levels of dimethyl sulfate in an aqueous soluble API intermediate using liquid–liquid extraction and GC–MS
- (2009) Jie Zheng et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Recent advances in trace analysis of pharmaceutical genotoxic impurities
- (2009) David Q. Liu et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Matrix deactivation: A general approach to improve stability of unstable and reactive pharmaceutical genotoxic impurities for trace analysis
- (2009) Mingjiang Sun et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Application of Quality by Design Principles to Support Development of a Control Strategy for the Control of Genotoxic Impurities in the Manufacturing Process of a Drug Substance
- (2009) Zadeo Cimarosti et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started