Nuclear receptors in regulation of biotransformation enzymes and drug transporters in the placental barrier

Nuclear-receptor–mediated regulation of drug– and bile-acid–transporter proteins in gut and liver

(2013) Jeff L. Staudinger et al.   DRUG METABOLISM REVIEWS

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

(2012) Yakun Chen et al.   BIOCHEMICAL PHARMACOLOGY

The Function of Cytochrome P450 1A1 Enzyme (CYP1A1) and Aryl Hydrocarbon Receptor (AhR) in the Placenta

(2012) Lucie Stejskalova et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

ABC drug transporter and nuclear receptor expression in human cytotrophoblasts: Influence of spontaneous syncytialization and induction by glucocorticoids

(2012) S. Manceau et al.   PLACENTA

In vitro toxicological effects of estrogenic mycotoxins on human placental cells: Structure activity relationships

(2012) Caroline Prouillac et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Placental transfer and metabolism: An overview of the experimental models utilizing human placental tissue

(2012) Päivi Myllynen et al.   TOXICOLOGY IN VITRO

Vitamin D, the placenta and pregnancy

(2011) N.Q. Liu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Interactions of the Aryl Hydrocarbon Receptor with Inflammatory Mediators:Beyond CYP1A Regulation

(2011) Jan Vondracek et al.   CURRENT DRUG METABOLISM

Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta

(2011) Amanda C. Filiberto et al.   Epigenetics

Transporter-mediated drug–drug interactions

(2011) Fabian Müller et al.   PHARMACOGENOMICS

Characterisation of the nuclear receptors FXR, PXR and CAR in normal and cholestatic placenta

(2011) V.L. Geenes et al.   PLACENTA

Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Nuclear Translocator Expression in Human and Rat Placentas and Transcription Activity in Human Trophoblast Cultures

(2011) Lucie Stejskalova et al.   TOXICOLOGICAL SCIENCES

Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression

(2011) Takeo Nakanishi et al.   Chinese Journal of Cancer

Role of transporter-mediated efflux in the placental biodisposition of bupropion and its metabolite, OH-bupropion

(2010) Sarah J. Hemauer et al.   BIOCHEMICAL PHARMACOLOGY

Approaches to deorphanization of human and microbial cytochrome P450 enzymes

(2010) F. Peter Guengerich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cytochrome P450 3As Gene Expression and Testosterone 6β-Hydroxylase Activity in Human Fetal Membranes and Placenta at Full Term

(2010) Kayoko Maezawa et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Gestational and Pregnane X Receptor-Mediated Regulation of Placental ATP-Binding Cassette Drug Transporters in Mice

(2010) S. S. Gahir et al.   DRUG METABOLISM AND DISPOSITION

Regulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids

(2010) Zdenek Dvorak et al.   DRUG METABOLISM REVIEWS

Expression of Aryl Hydrocarbon Receptor in Human Placentas and Fetal Tissues

(2010) Yi-zhou Jiang et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Aryl Hydrocarbon Receptor Is a Transcriptional Activator of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)

(2010) K. P. Tan et al.   MOLECULAR PHARMACOLOGY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Enhancing Functional Maturity before Preterm Birth

(2010) Mikko Hallman et al.   Neonatology

Vitamin D effects on pregnancy and the placenta

(2010) J.S. Shin et al.   PLACENTA

Effect of Maternal Tobacco Smoke Exposure on the Placental Transcriptome

(2010) H. Bruchova et al.   PLACENTA

Sex-specific associations between cortisol and birth weight in pregnancies complicated by asthma are not due to differential glucocorticoid receptor expression

(2010) N. A. Hodyl et al.   THORAX

Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5′-flanking region

(2009) Kouichi Yoshinari et al.   BIOCHEMICAL PHARMACOLOGY

Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene

(2009) Petr Pavek et al.   BIOCHEMICAL PHARMACOLOGY

Drug transporters in the human blood-placental barrier

(2009) Kirsi Vähäkangas et al.   BRITISH JOURNAL OF PHARMACOLOGY

Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects

(2009) Alessandra di Masi et al.   MOLECULAR ASPECTS OF MEDICINE

Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes

(2008) Radim Vrzal et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Xenobiotic-Induced Transcriptional Regulation of Xenobiotic Metabolizing Enzymes of the Cytochrome P450 Superfamily in Human Extrahepatic Tissues

(2008) Petr Pavek et al.   CURRENT DRUG METABOLISM

Expression of Glucocorticoid Receptor Messenger Ribonucleic Acid Transcripts in the Human Placenta at Term

(2008) Renée F. Johnson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Functional differences in steroid sulfate uptake of organic anion transporter 4 (OAT4) and organic anion transporting polypeptide 2B1 (OATP2B1) in human placenta

(2008) Bernhard Ugele et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Expression and activity of vitamin D receptor in the human placenta and in choriocarcinoma BeWo and JEG-3 cell lines

(2008) Katerina Pospechova et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Calcitriol affects hCG gene transcription in cultured human syncytiotrophoblasts

(2008) David Barrera et al.   Reproductive Biology and Endocrinology

Regulation of Transporters by Nuclear Hormone Receptors: Implications during Inflammation

(2007) Shirley Teng et al.   MOLECULAR PHARMACEUTICS