Article
Substance Abuse
Em Pijl, Tracy Oosterbroek, Brittany Dirk, Erin Mason
Summary: The purpose of this research was to understand the factors influencing SCS clients' choice to use safer smoking rooms instead of injecting. The findings suggest that personal, social, and environmental factors, such as personal history, preference, desire to be with friends, and space limitations in the SCS, play a role in the mode of consumption.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2023)
Article
Substance Abuse
Bianca Whiteside, Matthew Dunn
Summary: This article examines the representation and silencing of voices in the print news media regarding the first medically supervised injecting room in Victoria. The study finds that politicians largely focus on the rhetoric of "saving lives" while voices of people who inject drugs are inadequately represented and instead portrayed in a negative manner. The imbalanced reporting may have implications on the social status and drug policy of this population.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2023)
Article
Substance Abuse
Em Pijl, Tracy Oosterbroek, Takara Motz, Erin Mason, Keltie Hamilton
Summary: Peer assistance in injection drug use is a growing area of research. Participants in peer-assisted injection programs were more likely to be female and Indigenous. Injection providers felt a significant responsibility for the outcomes of assisting others in injection.
HARM REDUCTION JOURNAL
(2021)
Article
Substance Abuse
Nicole M. Miller, Claire Campbell, Gillian W. Shorter
Summary: This study aimed to identify barriers and facilitators to implementing naloxone and a supervised injection facility (SIF) to reduce opioid drug-related deaths in the Republic of Ireland (ROI) and Northern Ireland (NI). The findings highlighted stigma, police intimidation, and policy maker apathy as significant barriers to naloxone distribution and SIF implementation. Participants suggested peer-to-peer naloxone delivery and changing legislation as strategies to increase naloxone uptake, and recommended using webinars, Town Halls, and a Citizens' Assembly as advocacy tools for SIF implementation. Continued efforts to reduce stigma and increase accessibility to evidence-based interventions are crucial in addressing opioid drug-related deaths in ROI, NI, and beyond.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2023)
Article
Public, Environmental & Occupational Health
Wijnand Van Den Boom, Maria del Mar Quiroga, Dagnachew Muluye Fetene, Paul A. Agius, Peter G. Higgs, Lisa Maher, Matthew Hickman, Mark A. Stoov, Paul M. Dietze
Summary: The study found that the Medically Supervised Injecting Room in Melbourne attracted socially vulnerable people who inject drugs, who were more likely to report risky drug-related behaviors and poor health outcomes through the facility. Participants who frequently used the facility were more likely to live close to it.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Article
Economics
Jian Liang, Sergey Alexeev
Summary: A medically supervised injecting room, aimed at reducing harm from drug use, may lead to increased drug use, crime, and nuisance behavior, as well as a decrease in housing value.
REGIONAL SCIENCE AND URBAN ECONOMICS
(2023)
Article
Substance Abuse
Bianca Whiteside, Matthew Dunn
Summary: The study investigated the representation of Melbourne's medically supervised injecting room (MSIR) in print media, highlighting the dominance of discourse around the ‘drug problem’ of overdose. While the media often attributed ‘drug use’ to individual ‘choice’, the voices of people who inject drugs (PWID) were largely silenced. Reconceptualizing the ‘drug problem’ as a ‘health problem’ could aid in implementing harm reduction strategies successfully.
DRUG AND ALCOHOL REVIEW
(2022)
Article
Substance Abuse
Audrey D. Clark, Jason R. Lucey
Summary: Safer consumption sites (SCSs) help reduce risks of infection, injury, and death for drug users, with nurses playing important roles in reducing morbidity and mortality, creating a therapeutic community, and engaging in research and advocacy. More research is needed to understand and support the roles of SCS nurses in serving vulnerable populations.
JOURNAL OF ADDICTIONS NURSING
(2021)
Article
Substance Abuse
Mary Clare Kennedy, Kanna Hayashi, M. J. Milloy, Miranda Compton, Thomas Kerr
Summary: The expansion of overdose prevention sites in Vancouver, Canada in December 2016 was associated with immediate and continuous increases in supervised injection service engagement, as well as immediate improvements in related health outcomes. However, the results were inconclusive regarding the association between the intervention and subsequent changes in public injection, syringe sharing and addiction treatment participation.
Article
Public, Environmental & Occupational Health
A. Roxburgh, M. Livingston, P. Dietze, S. Nielsen, S. Cogger, M. Bartlett, C. Day, J. Latimer, M. Jauncey, N. Clark
Summary: The COVID-19 pandemic disrupted harm reduction and drug treatment services for people who inject drugs in Australia. The two supervised injecting facilities (SIFs) in Sydney and Melbourne were impacted differently by the pandemic, with decreased client visits and changes in drug injection patterns. The lockdown measures resulted in a decline in visits to the SIFs and a decrease in opioid overdose rates. Variations in drug use, including a shift towards methamphetamine in Sydney and co-injection of heroin and diphenhydramine in Melbourne, were observed.
Article
Substance Abuse
Amanda Roxburgh, Marianne Jauncey, Carolyn Day, Mark Bartlett, Shelley Cogger, Paul Dietze, Suzanne Nielsen, Julie Latimer, Nico Clark
Summary: The COVID-19 crisis has had profound impacts on health service provision, particularly on supervised injecting facilities and drug consumption rooms. Despite potential risks, two supervised injecting facilities in Australia have remained open during the pandemic, implementing strategies to continue providing services to drug users.
HARM REDUCTION JOURNAL
(2021)
Article
Substance Abuse
David Perlmutter, Courteney Wettemann, Callan Elswick Fockele, Tessa Frohe, Will Williams, Nathan Holland, Thea Oliphant-Wells, Hendrika Meischke, Jenna van Draanen
Summary: This study examines the perceptions and needs of emergency service providers (ESP) regarding the implementation of Supervised Consumption Sites (SCS). The study found that ESP prioritize their own safety while responding to calls involving drug use and suggest measures to enhance the perceived safety of SCS. ESP also express interest in utilizing SCS as an alternative care destination and emphasize the need for appropriate utilization of emergency services and a reduction in call volume to support the SCS model.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2023)
Article
Public, Environmental & Occupational Health
Michelle L. Pennington, Jessica Dupree, Elizabeth Coe, William Ostiguy, Nathan A. Kimbrel, Eric C. Meyer, Suzy B. Gulliver
Summary: This study is the first to identify FF-EMR perspectives related to working near a supervised injection facility (SIF). The study found positive and negative effects, preferences for duration of assignment, and a strong sense of duty among first responders.
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
(2021)
Article
Social Issues
Philip Mendes, Robert Taylor, Steven Roche
Summary: This study compares the official editorials of two major Melbourne newspapers regarding medically supervised injecting rooms (MSIR), revealing philosophical differences between them in terms of information sources, language, and highlighted issues. The Age mostly supports the establishment of MSIRs, while the Herald Sun's position is relatively ambiguous.
AUSTRALIAN JOURNAL OF SOCIAL ISSUES
(2023)
Article
Substance Abuse
Suzanne Nielsen, Monica Barratt, Sarah Hiley, Mark Bartlett, Julie Latimer, Marianne Jauncey, Claude Roux, Marie Morelato, Nico Clark, Michala Kowalski, Michael Gilbert, Leanne Francia, Alexandra Shipton, Dimitri Gerostamoulos, Linda Glowacki, Tina Lam
Summary: Australia has not yet experienced widespread fentanyl-contaminated heroin, but there is interest in developing methods to monitor for fentanyl and other potentially harmful novel psychoactive substances (NPS) in the country. Testing was conducted using urine screens, drug checking strips, and laboratory analysis of injecting equipment associated with opioid overdoses. The results showed a low number of positive fentanyl cases and highlighted the need for confirmatory testing.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2023)
Article
Pharmacology & Pharmacy
Pascal Menecier, Benjamin Rolland
Summary: There is currently no validated substitution treatment for alcohol addiction, but benzodiazepines are considered as a potential substitute. However, research on this topic is extremely limited. Benzodiazepines may play a role in the treatment of alcohol dependence, but more research is needed for validation.
ANNALES MEDICO-PSYCHOLOGIQUES
(2022)
Article
Psychology, Clinical
Daniela Dobre, Raymund Schwan, Claire Jansen, Thomas Schwitzer, Olivier Martin, Fabienne Ligier, Benjamin Rolland, Pierre Abdel Ahad, Delphine Capdevielle, Emmanuelle Corruble, Pascal Delamillieure, Sonia Dollfus, Dominique Drapier, Djamila Bennabi, Fabien Joubert, William Lecoeur, Catherine Massoubre, Antoine Pelissolo, Mathilde Roser, Christophe Schmitt, Noe Teboul, Clement Vansteene, Wanda Yekhlef, Antoine Yrondi, Radoine Haoui, Raphael Gaillard, Marion Leboyer, Pierre Thomas, Philip Gorwood, Vincent Laprevote
Summary: COVID-19 patients with severe psychiatric disorders have multiple somatic comorbidities and are at risk of developing a confusional state.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Mathieu Chappuy, Mikail Nourredine, Bertrand Clerc, Morgan Fahmi, Pauline Misslin, Maude Berthier, Louise Laloi, Benjamin Rolland
Summary: The study aimed to explore the dispensing of gabapentinoids in free healthcare centers in Lyon. The results showed a significant increase in the dispensing of pregabalin and gabapentin between 2016 and 2021. While pregabalin dispensing increased steadily, the dispensing of gabapentin fluctuated more over time.
FUNDAMENTAL & CLINICAL PHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Sophie-Athena Chapron, Mikail Nourredine, Clement Donde, Frederic Haesebaert, Jean-Arthur Micoulaud-Franchi, Pierre Alexis Geoffroy, Benjamin Rolland
Summary: Impulsivity is a key feature of many psychiatric disorders, and while topiramate showed some reduction in impulsivity levels in specific disorders, there is no clear-cut evidence supporting its transdiagnostic effectiveness in reducing impulsivity overall.
FUNDAMENTAL & CLINICAL PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Louise Carton, Florent Auger, Charlotte Laloux, Nicolas Durieux, Maeva Kyheng, Camille Potey, Sandrine Bergeron, Benjamin Rolland, Julie Deguil, Regis Bordet
Summary: This study investigated the separate and combined effects of acute exposure to ethanol and diazepam on hippocampal metabolite levels and delayed cognitive performance in rats. The findings suggest that the combination of ethanol and diazepam leads to a decrease in glutamate levels, while ethanol alone results in a decrease in GABA and glutamate levels and an increase in NAA levels. No significant differences were found in the behavioral assessment.
FUNDAMENTAL & CLINICAL PHARMACOLOGY
(2022)
Review
Gastroenterology & Hepatology
Alexandre Louvet, Jean-Baptiste Trabut, Christophe Moreno, Romain Moirand, Henri-Jean Aubin, Line Carolle Ntandja Wandji, Mikail Nourredine, Massih Ningarhari, Nathalie Ganne-Carrie, Georges-Philippe Pageaux, Francois Bailly, Jerome Boursier, Jean-Bernard Daeppen, Amandine Luquiens, Eric Nguyen-Khac, Rodolphe Anty, Thomas Orban, Helene Donnadieu-Rigole, Ariane Mallat, Christophe Bureau, Emile-Alexandre Pariente, Thierry Paupard, Amine Benyamina, Pascal Perney, Philippe Mathurin, Benjamin Rolland
Summary: Excessive alcohol consumption is the leading cause of liver diseases in Western countries, especially in France. The French Association for the Study of the Liver collaborated with the French Alcohol Society to develop guidelines summarizing the best evidence available in ARLD.
LIVER INTERNATIONAL
(2022)
Article
Psychiatry
Thomas Fovet, Maelle Baillet, Mathilde Horn, Christine Chan-Chee, Olivier Cottencin, Pierre Thomas, Guillaume Vaiva, Fabien D'Hondt, Ali Amad, Antoine Lamer
Summary: This study investigated the psychiatric hospital treatment of people declared not criminally responsible on account of mental disorder (NCRMD) in France. The results showed that these patients were mostly young men diagnosed with a psychotic disorder. The majority of patients received treatment in general psychiatric hospitals, with a median hospitalization duration of 13 months. The rehospitalization rate within 5 years of discharge was 62%.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Public, Environmental & Occupational Health
Sabine Bayen, Sabrina Talbi, Charles Cauet, Fawaz Joomun, Olivier Cottencin, Caroline Moreau, Luc Defebvre, David Devos, Nassir Messaadi
Summary: This study aims to explore possible forms of domestic violence suffered by men with Parkinson's disease. Through qualitative research and content analysis, it was found that men with Parkinson's disease may experience neglect, fear, distance in sexual and physical intimacy, as well as mockery, humiliation, and physical violence in their domestic relationships. The results of this study suggest that healthcare professionals should screen for domestic violence when communicating with men with Parkinson's disease.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Psychology, Experimental
Clara De Groote, Olivier Cottencin, Philippe Tison, Claire Triquet, Jean-Louis Nandrino
Summary: The study investigated the relationship between autobiographical memories and individuals' self-conception in alcohol use disorder (AUD). AUD detoxified patients and control participants were asked to create a list of self-statements associated with autobiographical memories. The group variable was not linked to the number of positive self-statements, but it was associated with the number of negative self-statements. Additionally, the memories cued by positive self-statements were related to the group and the number of positive and general memories, while there was no association for the memories cued by negative self-statements. The use of adaptive emotional regulation strategies was the only significant predictor of the use of positive or negative self-statements in AUD patients.
Article
Neurosciences
Geraldine Petit, Sophie Leclercq, Caroline Quoilin, Marie Poncin, Peter Starkel, Pierre Maurage, Benjamin Rolland, Laurence Dricot, Philippe De Timary
Summary: After detoxification treatment, depressive symptoms in male SAUD patients were associated with reduced cortical thickness in the right superior temporal gyrus. Anxiety level was correlated with lower cortical thickness in various regions of the left hemisphere and a large cluster in the right middle temporal region. These findings suggest that the intensity of depressive and anxiety symptoms at the end of treatment is inversely associated with cortical thickness in emotion-related brain regions, explaining the persistence of symptoms.
NEUROPSYCHOPHARMACOLOGY REPORTS
(2023)
Article
Gastroenterology & Hepatology
Coralie Torres, Guillaume Bauer, Sabrina Aubriet, Caroline Scholtes, Francois Bailly, Marianne Maynard-Muet, Pierre Pradat, Francoise Pillot-Meunier, Louis-Ferdinand Lespine, Benjamin Rolland
Summary: This study conducted a retrospective analysis of HCV serology results in a psychiatric hospital in France, aiming to explore the characteristics of seropositive patients with and without a positive viral load. The findings revealed that among the HCV-positive patients, a subgroup had no active HCV infection. These individuals without identified risk factors for HCV are more likely to be PWMDs yet to be treated for HCV, highlighting the importance of systematic screening in this population in the context of HCV elimination.
JOURNAL OF VIRAL HEPATITIS
(2023)
Article
Substance Abuse
Thomas Fovet, Marielle Wathelet, Massil Benbouriche, Imane Benradia, Jean-Luc Roelandt, Pierre Thomas, Fabien D'Hondt, Benjamin Rolland
Summary: Alcohol and illegal drug use, as well as substance use disorders, are highly prevalent in French prison populations, especially among men entering jail. Rates of AUD and DUD in the jail population are significantly higher compared to the general population, and there is a stronger association with co-occurring psychiatric disorders in incarcerated individuals.
EUROPEAN ADDICTION RESEARCH
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Benjamin Rolland, Elias Benabadji, Olivier Lada, Pascaline Rabiega, Fayssoil Fouad, Nabil Hallouche, Stanislas Pol
JOURNAL OF HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Alexandre Louvet, Julien Labreuche, Christophe Moreno, Claire Vanlemmens, Romain Moirand, Cyrille Feray, Jerome Dumortier, Georges-Philippe Pageaux, Christophe Bureau, Faiza Chermak, Christophe Duvoux, Dominique Thabut, Vincent Leroy, Nicolas Carbonell, Benjamin Rolland, Ephrem Salame, Rodolphe Anty, Jerome Gournay, Jean Delwaide, Christine Silvain, Valerio Lucidi, Guillaume Lassailly, Sebastien Dharancy, Eric Nguyen-Khac, Didier Samuel, Alain Duhamel, Philippe Mathurin
Summary: This study compared the effectiveness of early liver transplantation and standard liver transplantation in patients with alcohol-related hepatitis. The study found that early liver transplantation did not reduce the rate of alcohol relapse, but it improved the survival rate of patients. High alcohol intake was more common after early liver transplantation.
LANCET GASTROENTEROLOGY & HEPATOLOGY
(2022)
