Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via reducing CYP2E1 activity and oxidative stress

New metabolite profiles of Danshensu in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry

(2014) Jun-fei Gu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2,3,5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes

(2012) Ru Feng et al.   PHYTOMEDICINE

Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes

(2011) Wayne Y.W. Lee et al.   PHYTOMEDICINE

Pharmacokinetic interactions induced by content variation of major water-soluble components of Danshen preparation in rats

(2010) Bo-bo Chang et al.   ACTA PHARMACOLOGICA SINICA

Induction or inhibition of cytochrome P450 2E1 modifies the acute toxicity of acrylonitrile in rats: biochemical evidence

(2010) Wang Suhua et al.   ARCHIVES OF TOXICOLOGY

Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro

(2010) Xin Wang et al.   PHYTOMEDICINE

Silymarin protects PBMC against B(a)P induced toxicity by replenishing redox status and modulating glutathione metabolizing enzymes—An in vitro study

(2010) P.V. Kiruthiga et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Beneficial effects of danshensu, an active component of Salvia miltiorrhiza, on homocysteine metabolism via the trans-sulphuration pathway in rats

(2009) YG Cao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection

(2009) Jyotirmoy Ghosh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acetaminophen Hepatotoxicity and Acute Liver Failure

(2009) Linda J. Chun et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Glutathione in liver diseases and hepatotoxicity

(2008) Liyun Yuan et al.   MOLECULAR ASPECTS OF MEDICINE

Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation

(2007) W.Y.W. Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B

(2007) Guang-Rong Zhao et al.   FOOD AND CHEMICAL TOXICOLOGY