Article
Medicine, General & Internal
Mehmet Resit Sonmez, Isa Caner Aydin, Guelsah Bicer, Nuri Havan, Ahmet Orhan Sunar, Serkan Ademoglu, Mehmet Omer Ozduman, Mursit Dincer, Erdal Polat, Mustafa Duman
Summary: This study aimed to investigate the effects of perirenal fat thickness on postoperative complications and prognosis in patients undergoing surgery for colorectal cancer. Increased perirenal fat thickness was found to be an independent risk factor for postoperative complications. Measurement of perirenal fat thickness as an indicator of visceral fat volume can be used to identify high-risk patients and potentially impact disease management and patient information.
Article
Radiology, Nuclear Medicine & Medical Imaging
Binit Sureka, Thomas George, Mahendra Kumar Garg, Mithu Banerjee, Surender Deora, Ravinder Sukhla, Akhil Goel, Pawan Kumar Garg, Taruna Yadav, Pushpinder Singh Khera
Summary: This study aimed to investigate the feasibility of using VFV, SFV, and VSR to detect metabolically obese normal weight individuals in the Asian Indian population. The results showed that patients with metabolic risk factors had significantly higher VFV, SFV, and VSR compared to those without risk factors. The volume of subcutaneous fat was significantly higher in females than males. The cutoff values for predicting at least one metabolic syndrome differed between males and females.
EUROPEAN RADIOLOGY
(2023)
Article
Endocrinology & Metabolism
Liping Han, Chaoyi Deng, Rui Zhao, Qianyi Wan, Xiaofang Zhang, Xiao Wang, Yi Chen
Summary: This study aimed to investigate the correlation between visceral fat area (VFA) and early postoperative complications in patients with obesity undergoing bariatric surgery. Patients were divided into two groups based on umbilical level VFA, and the high-VFA group had a higher incidence of early postoperative complications compared to the low-VFA group. The study suggests that excess VFA is an independent risk factor for early postoperative complications following bariatric surgery. Rating: 8/10
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Ming Jiang, Menghuan Li, Cuiying Liu, Lei Jing, Qiong Huang, Tingting Wu, Xiangqing Kong, Jing Liu
Summary: This study conducted on Chinese adults found a positive independent relationship between perirenal fat volume (PrFV) and serum uric acid (SUA) levels, suggesting that perirenal fat may be a potential risk factor for elevated SUA levels.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Debora Basile, Michele Bartoletti, Maurizio Polano, Lucia Bortot, Lorenzo Gerratana, Paola Di Nardo, Matteo Borghi, Valentina Fanotto, Giacomo Pelizzari, Camilla Lisanti, Mattia Garutti, Silvia Buriolla, Elena Ongaro, Eva Andreuzzi, Marcella Montico, Luca Balestreri, Gianmaria Miolo, Giuseppe Toffoli, Giuseppe Aprile, Fabio Puglisi, Angela Buonadonna
Summary: This study investigated the prognostic role of adiposity, especially visceral fat, in patients with metastatic colorectal cancer. The results showed that higher visceral fat values were associated with worse outcomes in these patients. Further research is needed to explore the impact of visceral fat on colorectal cancer patients.
CLINICAL NUTRITION
(2021)
Article
Urology & Nephrology
Haichao Huang, Shi Chen, Wenzhao Zhang, Tao Wang, Peide Bai, Jinchun Xing, Huiqiang Wang, Bin Chen
Summary: This study aimed to evaluate the association between perirenal fat thickness (PFT) and recurrence-free survival (RFS) in a Chinese population with unilateral nephrolithiasis. The results showed that high PFT was significantly associated with higher BMI and hyperlipidemia. During the follow-up period, patients with low PFT had better RFS compared to those with high PFT. Male sex and high PFT were identified as significant risk factors for poor RFS.
Article
Endocrinology & Metabolism
Xiangjun Chen, Yun Mao, Jinbo Hu, Shichao Han, Lilin Gong, Ting Luo, Shumin Yang, Hua Qing, Yue Wang, Zhipeng Du, Mei Mei, Li Zheng, Xinlu Lv, Ying Tang, Qinying Zhao, Yangmei Zhou, John Cijiang He, Qifu Li, Zhihong Wang
Summary: Perirenal fat is a stronger predictor for chronic kidney disease (CKD) in patients with type 2 diabetes mellitus compared to total, subcutaneous, or visceral fat. Perirenal fat thickness is negatively correlated with eGFR and an increase in PRFT at baseline is associated with a higher incidence of CKD.
Article
Cardiac & Cardiovascular Systems
Francisco J. Osuna-Prieto, Borja Martinez-Tellez, Lourdes Ortiz-Alvarez, Xinyu Di, Lucas Jurado-Fasoli, Huiwen Xu, Victoria Ceperuelo-Mallafre, Catalina Nunez-Roa, Isabelle Kohler, Antonio Segura-Carretero, Jose Garcia-Lario, Angel Gil, Concepcion M. Aguilera, Jose M. Llamas-Elvira, Patrick C. N. Rensen, Joan Vendrell, Jonatan R. Ruiz, Sonia Fernandez-Veledo
Summary: The study found that plasma succinate levels are associated with higher levels of visceral adipose tissue, triglycerides, C-reactive protein, diastolic blood pressure, and pro-inflammatory omega-6 oxylipins in individuals. Additionally, succinate levels are higher in metabolically unhealthy individuals compared to healthy overweight/obese peers, with no association between succinate levels and brown adipose tissue or fecal microbiota composition and diversity.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Surgery
Nathalie Auger, U. Vivian Ukah, Maeva Monnier, Marianne Bilodeau-Bertrand, Natalie Dayan
Summary: This study analyzed 2,412,075 deliveries in Quebec, Canada between 1989 and 2019, finding that pregnant women with prior bariatric surgery have similar risks as nonobese women for most types of severe maternal morbidity, except for intensive care unit admission.
Review
Oncology
Linchong Yu, Wenjiang Wu, Shijun Xia, Yue Li, Zhigang Xu
Summary: This study aimed to explore the relationship between visceral obesity (VO) and anastomotic leakage after colon cancer surgery. The meta-analysis of 7 studies found that patients with VO had a higher incidence of anastomotic leakage compared to those without VO. The findings confirmed that VO is a reliable risk factor for colon cancer surgery.
FRONTIERS IN ONCOLOGY
(2023)
Article
Nutrition & Dietetics
Heeju Lim, Kumhee Son, Hyunjung Lim
Summary: Sarcopenic obesity (SO) is more associated with cardiovascular diseases than sarcopenia or obesity alone. This study aimed to assess the association between the skeletal muscle mass-to-visceral fat area ratio (SVR) and dietary and cardiometabolic health risk factors in obese women. The SVR was inversely correlated with blood lipids and hs-CRP, while fatty acid intake was inversely correlated with the SVR. Conversely, vitamin B-6 and B-12 intake showed positive associations with the SVR.
Article
Medicine, General & Internal
Juan Shi, Guoqing Bao, Jie Hong, Simin Wang, Yufei Chen, Shaoqian Zhao, Aibo Gao, Ru Zhang, Jingfen Hu, Wenjie Yang, Fuhua Yan, Ankang Lyu, Ruixin Liu, Bin Cui, Yuhong Chen, Jiabin Jin, Baiyong Shen, Yifei Zhang, Weiqiong Gu, Dagan Feng, Weiqing Wang, Jiqiu Wang, Xiuying Wang, Guang Ning
Summary: Texture features of VAT, extracted from CT scans and analyzed with machine learning, can predict metabolic disorders and estimate surgery-induced weight loss effects. These findings have important implications for understanding the role of visceral adipose tissue in metabolic disorders and surgical interventions.
Article
Endocrinology & Metabolism
Xiu Li Guo, Mei Tu, Yang Chen, Wei Wang
Summary: The study found a significant association between perirenal fat thickness and metabolic syndrome in Chinese newly diagnosed type 2 diabetes patients, with good predictive value. Thus, perirenal fat thickness may serve as an applicable surrogate marker for metabolic syndrome in Chinese individuals newly diagnosed with T2DM.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Surgery
Joonas H. Kauppila, Giola Santoni, Wenjing Tao, Elsebeth Lynge, Jussi Jokinen, Laufey Tryggvadottir, Eivind Ness-Jensen, Eero Pukkala, My Von Euler-Chelpin, Jesper Lagergren
Summary: This study identified risk factors for suicide after bariatric surgery, including gender, surgery type, and psychiatric disorders. Female patients had a lower risk of suicide compared to males, while gastric bypass surgery had a lower risk compared to other types of bariatric surgery. Patients with a history of depression or anxiety, mania, bipolar disorder, psychosis, schizophrenia, or substance use were at an increased risk of suicide.
Article
Public, Environmental & Occupational Health
Soren Rattenborg, Soeren Moeller, Erik Frostberg, Hans B. Rahr
Summary: The purpose of this study was to examine the variation in the prevalence of patient-related risk factors for adverse outcomes of colorectal cancer treatment between hospitals in Denmark. A national cohort of 44,471 CRC patients registered in the Danish Colorectal Cancer Group database from 2009 to 2018 was included. Patient-related risk factors were collected from national Danish registers, and prediction models were used to examine the impact on outcomes and variations between hospitals.
CLINICAL EPIDEMIOLOGY
(2023)
Article
Multidisciplinary Sciences
Jeremy Meyer, Roberto Cirocchi, Salomone Di Saverio, Frederic Ris, James Wheeler, Richard Justin Davies
Summary: Professional surgical societies recommend identification and treatment of pre-operative anemia in abdominal surgery patients. This study aimed to determine if pre-operative iron can correct hemoglobin levels and reduce peri-operative blood transfusion in major abdominal surgery. The results show that pre-operative iron increases hemoglobin concentration but does not reduce the need for blood transfusions during surgery.
SCIENTIFIC REPORTS
(2022)
Article
Surgery
Jeffrey Dalli, Sarah Shanahan, Niall P. Hardy, Manish Chand, Roel Hompes, David Jayne, Frederic Ris, Antonino Spinelli, Steven Wexner, Ronan A. Cahill
Summary: This study examines the interpretative capability of experts in Indocyanine green fluorescence angiography (ICGFA) by analyzing the fluorescence signal patterns of expert-annotated surgical videos. The results show that experts demonstrate high correlation in their signal interpretation, although they do so tacitly. The findings of this study are important for the development of vocabulary, training sets, and computer vision methodology in exploiting ICGFA technology.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Johanna J. Joosten, Gregoire Longchamp, Mohammad F. Khan, Wytze Lameris, Mark I. van Berge Henegouwen, Wilhelmus A. Bemelman, Ronan A. Cahill, Roel Hompes, Frederic Ris
Summary: Intraoperative fluorescence angiography (FA) is a valuable tool for assessing bowel viability during acute surgical procedures. This study reports on the use of FA in emergency abdominal surgery and its impact on intraoperative decision making. Results show that FA changed management in approximately one out of four patients, enabling bowel preservation and avoiding unnecessary resections. However, further prospective studies are needed to optimize the use of FA in this indication.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Gastroenterology & Hepatology
Alexandre Balaphas, Jeremy Meyer, Nicolas C. Buchs, Ali Modarressi, Leo H. Buhler, Christian Toso, Carmen Gonelle-Gispert, Frederic Ris
Summary: This study reports the presence of mesenchymal stem cells in the anal canal transition zone in pigs for the first time, and demonstrates the feasibility of their isolation. These findings offer potential for isolating human anal canal transition zone mesenchymal stem cells, which could be used to study sphincters healing and treat anal incontinence.
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Orthopedics
Alexandre Ansorge, Michael de Foy, Angel Gayet Aregon, Elisabeth Andereggen, Axel Gamulin
Summary: This study aimed to determine the incidence and characteristics of high-energy pelvic ring injuries (PRI) and compare them to other high-energy blunt trauma. The results showed that the incidence of type B or C PRI was comparable to previous studies. Women were less likely to sustain high-energy blunt trauma, but when they did, they were more likely to have type B or C PRI. Despite higher injury severity, complication and death rates were similar between type B or C PRI patients and other high-energy blunt trauma patients.
ORTHOPAEDICS & TRAUMATOLOGY-SURGERY & RESEARCH
(2023)
Article
Medicine, Research & Experimental
Jean Yaniss Perentes, Michel Christodoulou, Etienne Abdelnour-Berchtold, Wolfram Karenovics, Angele Gayet-Ageron, Michel Gonzalez, Thorsten Krueger, Frederic Triponez, Philippe Terrier, Benoit Bedat
Summary: This study aims to compare the pain outcomes at 2 months after rib osteosynthesis versus medical therapy for patients with uncomplicated rib fractures. By evaluating the clinical effects of rib fixation, the study may provide insights into whether surgical treatment can improve patient recovery and reduce the medico-economic burden.
Article
Environmental Sciences
Lamyae Benzakour, Angele Gayet-Ageron, Maria Jubin, Francesca Suardi, Chloe Pallud, Fanny-Blanche Lombard, Beatrice Quagliarini, Manuella Epiney
Summary: This study reveals the challenges of early mental health screening during childbirth and finds a modest influence of stress factors directly related to the COVID-19 pandemic on the risk of birth-related post-traumatic stress disorder (PTSD).
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Thomas Perneger, Angele Gayet-Ageron
Summary: This study aims to estimate the strength of evidence for the null hypothesis vs the effectiveness hypothesis in statistically nonsignificant primary outcome results of randomized clinical trials. The results demonstrate that many trials provide strong support for the null hypothesis of no effect.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Surgery
Charles-Henri Wassmer, Rebecca Revol, Isabelle Uhe, Mickael Chevallay, Christian Toso, Pascal Gervaz, Philippe Morel, Pierre-Alexandre Poletti, Alexandra Platon, Frederic Ris, Frank Schwenter, Thomas Perneger, Raphael P. H. Meier
Summary: A practical clinical severity score was developed and validated to guide the management of patients with small bowel obstruction.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Multidisciplinary Sciences
Christophe Marti, Christophe Gaudet-Blavignac, Jeremy Martin, Christian Lovis, Jerome Stirnemann, Olivier Grosgurin, Fiona Novotny, Anne Iten, Aline Mendes, Virginie Prendki, Christine Serratrice, Pauline Darbellay Farhoumand, Nour Abidi, Pauline Vetter, Sebastian Carballo, Jean-Luc Reny, Amandine Berner, Angele Gayet-Ageron
Summary: Therapeutic strategies for COVID-19 patients in Switzerland were adapted during the second wave, leading to a reduction in hospital mortality, ICU admission, and length of hospital stay compared to the first wave. These adaptations included the use of corticosteroids therapy and increased admission to the IMCU for non-invasive respiratory support. The increased number of patients admitted during the second wave was accompanied by a higher proportion of medical decisions restraining ICU admission, indicating potential improvement in patient selection or implicit triaging.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Julien Maillard, Nadia Elia, Frederic Ris, Delphine S. Courvoisier, Dina Zekry, Intidhar Labidi Galy, Christian Toso, Stefan Monig, Isabelle Zaccaria, Bernhard Walder
Summary: This study aims to describe the patterns of HRQoL changes at 6 months after high-risk oncological surgery and assess the level of regret among patients and their next-of-kin regarding the decision to undergo surgery. Patients over 18 years old undergoing specific surgeries are included in this prospective observational cohort study. The primary outcome is the proportion of patients with changes in HRQoL at 6 months after surgery, while the secondary outcome is to assess regret levels.
Article
Medicine, General & Internal
Khaoula Ben Messaoud, Sara Schroter, Mark Richards, Angele Gayet-Ageron
Summary: This study aims to describe gender and geographical inequalities in invitations to review and the response to these invitations and to assess whether inequalities increased during the covid-19 pandemic. The study found that gender, geographical affiliation, and country income were closely associated with the agreement to review. The study also found that the agreement rate was lower during different phases of the pandemic compared to the pre-pandemic period.
BMJ-BRITISH MEDICAL JOURNAL
(2023)
Review
Oncology
Julie Mareschal, Alexandra Hemmer, Jonathan Douissard, Yves Marc Dupertuis, Tinh-Hai Collet, Thibaud Koessler, Christian Toso, Frederic Ris, Laurence Genton
Summary: Gastrointestinal cancer surgery is the primary treatment for gastrointestinal cancers. Prehabilitation before surgery aims to optimize the patient's condition and improve postoperative recovery. This review summarizes the latest evidence of preoperative prehabilitation on postoperative outcomes and discusses potential therapeutic targets. Preoperative interventions combining nutrition and physical activity show improvements in physical performance and quality of life in patients with esophagogastric and colorectal cancers, but no benefits in postoperative complications and mortality. Further studies are needed to confirm these findings and identify patients who will benefit from prehabilitation.
Article
Obstetrics & Gynecology
Fabio Mauri, Fanny Schumacher, Marta Weber, Angele Gayet-Ageron, Begona Martinez de Tejada
Summary: The study found that Swiss obstetrics and gynecology professionals generally believed that the caesarean section rate was too high and actions were needed to reduce this rate. Improving patient education and professional training were considered as the main strategies to be explored.
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY-X
(2023)
Letter
Medicine, General & Internal
Khaoula Ben Messaoud, Sara Schroter, Mark Richards, Angele Gayet-Ageron
BMJ-BRITISH MEDICAL JOURNAL
(2023)
