Article
Immunology
Jennifer Holder-Murray, Andrew Yeh, Matthew B. Rogers, Brian Firek, Brandon Mahler, David Medich, James Celebrezze, Michael J. Morowitz
Summary: The study examined temporal and spatial changes in the skin microbiota of patients undergoing colorectal surgery. Results showed a decrease in skin microbiome diversity post-surgery, with a transient loss of commensal bacteria replaced by potential pathogens and anaerobes. The study suggests real-time monitoring of skin microbiome could offer insights into the pathogenesis of SSIs.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Surgery
Asiri Arachchi, Alice Lee, Manisha Metlapalli, Ellathios Antoniou, Ruben Rajan, Vignesh Narasimhan, Ashray Rajagopalan, Seraphina Key, William M. K. Teoh, Thang Chien Nguyen, James Tow-Hing Lim, Hanumant Chouhan, Bruce P. Waxman, Julian A. Smith
Summary: In open colorectal surgery, the use of the HumiGard (TM) surgical humidification system to insufflate warm, humidified CO2 does not significantly reduce the incidence of surgical site infections (SSI), but it does increase the average core temperature at the end of surgery.
ANZ JOURNAL OF SURGERY
(2023)
Article
Gastroenterology & Hepatology
Cary Jo R. Schlick, Reiping Huang, Brian C. Brajcich, Amy L. Halverson, Anthony D. Yang, Lindsey Kreutzer, Karl Y. Bilimoria, Michael F. McGee
Summary: The implementation of surgical site infection reduction bundles plays an important role in reducing surgical site infections, but different bundle elements have varying associations with infection reduction. Therefore, it is necessary to focus on the specific elements that have an impact on infection reduction during the implementation process.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Dermatology
Jiang Liu, Gang Li, Zhiliang Chen, Huafeng Jiang
Summary: We conducted a meta-analysis to evaluate the impact of different body mass index on surgical wound infection after colorectal surgery. A total of 2349 related studies were evaluated, with 15,595 colorectal surgery subjects participating in the selected studies' baseline trials. The results showed that subjects with higher body mass index had a significantly higher surgical wound infection rate after colorectal surgery compared to those with a normal body mass index.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Gastroenterology & Hepatology
Nicola Reeves, Simone Cuff, Kathryn Boyce, Rhiannon Harries, Christopher Roberts, Wendy Harrison, Jared Torkington
Summary: This study aimed to accurately record the 30-day SSI rate after surgery performed by colorectal surgeons nationally within Wales. The study found an overall SSI rate of 13%, with 49.3% of these SSIs being diagnosed in primary care.
COLORECTAL DISEASE
(2021)
Article
Surgery
Eugene P. Ceppa, Rachel C. Kim, Donna Niedzwiecki, Melissa E. Lowe, Dana A. Warren, Michael G. House, Attila Nakeeb, Sabino Zani, Ashley N. Moyer, Dan G. Blazer
Summary: Despite established guidelines and procedures, surgical site infections (SSI) after major abdominal operations remain a significant problem. While negative pressure therapy (NPT) has been effective for open wounds, the role of closed incision NPT (ciNPT) is still uncertain.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2023)
Review
Public, Environmental & Occupational Health
M. F. Bath, R. Suresh, J. Davies, M. R. Machesney
Summary: The study found that pulsed lavage significantly reduces the rate of SSIs in surgical procedures, with the most pronounced effect seen in abdominal operations. However, the current study quality is low, and further randomized controlled trials are needed to fully assess the potential benefits of pulsed lavage in reducing SSIs.
JOURNAL OF HOSPITAL INFECTION
(2021)
Review
Surgery
Elisabeth C. McLemore, Lawrence Lee, Traci L. Hedrick, Laila Rashidi, Erik P. Askenasy, Daniel Popowich, Patricia Sylla
Summary: As enhanced recovery programs (ERPs) have evolved, the length of hospitalization following elective minimally invasive colorectal surgery has decreased. The interest in ambulatory colectomy has increased during the COVID-19 pandemic, leading to further reductions in length of stay.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Surgery
Michael F. Bath, Jordan Powell, Ismail Ismail, Michael R. Machesney
Summary: This study assessed the effects of pulsed lavage (PL) irrigation on SSI rates following laparotomy and found that PL significantly reduced the rate of SSI. The use of PL could be a cost-effective means to reduce the incidence of this common and expensive post-operative complication. Further prospective randomized trials are needed to fully evaluate its benefits and wider use within general surgery.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Dermatology
Shuangyun Zheng, Xiaole Liu, Liqin Cheng, Qiaozhu Wu, Fanhang Meng
Summary: In this meta-analysis, the effect of minimally invasive surgery and laparotomy on wound infection and postoperative and intraoperative complications in the management of cervical cancer was evaluated. The results showed that minimally invasive surgery had significantly lower rates of wound infection and postoperative complications compared to laparotomy, but had no significant difference in intraoperative complications for subjects with cervical cancer.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Gastroenterology & Hepatology
Matthias Mehdorn, Woubet Tefera Kassahun, Norman Lippmann, Uwe Scheuermann, Linda Groos, Dorina Buchloh, Boris Jansen-Winkeln, Ines Gockel
Summary: Analysis of microbiological isolates in patients with SSSI after abdominal surgery identified Enterococcus spp. and Enterobacterales as main bacteria, with surgical revision as a major risk factor for changes in bacterial isolates.
JOURNAL OF GASTROINTESTINAL SURGERY
(2022)
Article
Medicine, General & Internal
Josep M. Badia, Miriam Flores-Yelamos, Ana Vazquez, Nares Arroyo-Garcia, Mireia Puig-Asensio, David Pares, Miguel Pera, Joaquin Lopez-Contreras, Enric Limon, Miquel Pujol
Summary: Oral antibiotic prophylaxis reduced the rates of surgical site infections in elective colorectal surgery and demonstrated a protective effect in multivariate analysis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Surgery
Shinsei Matsuoka, Takayuki Kondo, Ryo Seishima, Koji Okabayashi, Masashi Tsuruta, Kohei Shigeta, Takashi Ishida, Hirotoshi Hasegawa, Yuko Kitagawa
Summary: A study of 77 laparoscopic colorectal surgeries found a glove perforation rate of 1.1%, with no significant correlation between the duration of surgery and glove perforation. There was also no significant connection found between glove perforation and postoperative surgical site infections.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Biology
Gearoid Mc Geehan, Itoro M. Edelduok, Magda Bucholc, Angus Watson, Zsolt Bodnar, Alison Johnston, Michael Sugrue
Summary: This study conducted a systematic review and meta-analysis of factors affecting the development of surgical site infection in patients undergoing midline emergency laparotomy, highlighting a significant deficit in the world literature regarding this topic. The analysis showed a non-significant reduction in SSI rates after implementing wound bundles, indicating a need for urgent assessment of bundles' potential to improve outcomes in emergency laparotomy.
Article
Public, Environmental & Occupational Health
L. K. Dixon, S. Biggs, D. Messenger, J. Shabbir
Summary: The study aimed to reduce the rate of superficial surgical site infections (SSIs) after elective colorectal surgery by implementing a bundle of evidence-based interventions. Following the implementation of measures such as triclosan-coated sutures, 2% chlorhexidine skin preparation, and the use of warmed carbon dioxide (CO2), the rate of superficial SSIs was significantly reduced.
JOURNAL OF HOSPITAL INFECTION
(2022)
Editorial Material
Surgery
Allan M. F. Kwok, Neryan A. Thomas, Stephen R. Smith
ANZ JOURNAL OF SURGERY
(2022)
Article
Surgery
Stephen Ridley Smith, Jon Gani, Rosemary Carroll, Natalie Lott, Jacob Hampton, Christopher Oldmeadow, Mathew Clapham, John Attia
Summary: This study compares the SSI rates of three skin preparation agents and finds that PI-Alc is non-inferior to C-Alc but not superior to PI-Aq. This contradicts current guidelines.
Article
Gastroenterology & Hepatology
Fiona S. Reid, Bree Stephensen, Rosemary Carroll, Natalie Lott, John R. Attia, Stephen R. Smith
Summary: This study compared the efficacy of chlorhexidine in alcohol, povidone-iodine in alcohol, and povidone-iodine in aqueous solution for preventing surgical site infection in colorectal surgery. The results showed no difference in surgical site infection, complications, or length of stay among the three skin preparation methods.
DISEASES OF THE COLON & RECTUM
(2022)
Article
Pediatrics
Sergey Vavilov, Elysa Roberts, Grahame H. H. Smith, Malcolm Starkey, Peter Pockney, Aniruddh Deshpande
Summary: This study reports on decision regret in Australian parents who accepted or declined surgery for their son's hypospadias repair, and explores the underlying factors for decision-making, satisfaction, and regret. The results indicate that parents who chose surgery were primarily concerned about function, while parents who declined surgery had the highest level of decision regret.
JOURNAL OF PEDIATRIC UROLOGY
(2022)
Article
Surgery
Melissa Stieler, Peter Pockney, Cassidy Campbell, Vaisnavi Thirugnanasundralingam, Lachlan Gan, Matthew J. Spittal, Gregory Carter
Summary: Somatic syndromes are common psychiatric presentations associated with higher healthcare expenditure and longer hospital stays in patients with abdominal pain.
Review
Gastroenterology & Hepatology
Brent Gilbert, Gerard Kaiko, Stephen Smith, Peter Wark
Summary: Cystic fibrosis (CF) is a hereditary, life-limiting, multi-system condition that results in chronic respiratory infections, pancreatic insufficiency and intestinal inflammation. Evidence indicates that CF patients develop colorectal cancer (CRC) earlier and more often than the general population. Intestinal dysbiosis resulting from genetics and CF treatment is a contributing factor.
COLORECTAL DISEASE
(2023)
Editorial Material
Surgery
Natalie Lott, Stephen Smith, Jonathan Gani, Penny Reeves
ANZ JOURNAL OF SURGERY
(2023)
Article
Surgery
Veral Vishnoi, Emily C. Hoedt, Tiffany Gould, Georgia Carroll, Rosemary Carroll, Natalie Lott, Peter Pockney, Stephen R. Smith, Simon Keely
Summary: This study utilized 16S rRNA sequencing to analyze the microbial profile of surgical sites in colorectal surgery. The findings suggest a potential association between intraoperative microbial composition and postoperative infection, but further research is needed to validate these results and determine their clinical significance.
ANZ JOURNAL OF SURGERY
(2023)
Article
Surgery
Yan Joyce Ming, Peter Howley, Merran Holmes, Jon Gani, Peter Pockney
Summary: Risk assessment is crucial for emergency laparotomy to guide decision-making and predict perioperative care. The psoas muscle to 3rd lumbar vertebra area ratio (PM:L3) measured on CT scans is inversely associated with mortality in EL patients. Combining PM:L3 with simplified ASA classification provides a simple and effective alternative to established risk assessment scores.
ANZ JOURNAL OF SURGERY
(2023)
Article
Gastroenterology & Hepatology
Allan M. F. Kwok, Stephen R. Smith, Jie Zhao, Rosemary Carroll, Lucy Leigh, Brian Draganic
Summary: This study aimed to determine whether topical lidocaine, with or without diltiazem, is more effective than placebo for analgesia after hemorrhoid banding. The study found that lidocaine and lidocaine/diltiazem were both effective in reducing pain and improving patient satisfaction, with no difference in complications between the groups.
DISEASES OF THE COLON & RECTUM
(2023)
Review
Infectious Diseases
Veral Vishnoi, Tristan Morey, Emily C. C. Hoedt, Simon Keely, Peter Pockney, Stephen R. Smith
Summary: Surgical site harbors bacteria, and both traditional culture and genomic sequencing provide insights into the role of bacteria in surgical site infection. Culture-dependent techniques can predict infection but have limitations, while culture-independent studies reveal the complexity of the microbial community and suggest factors influencing susceptibility to infection.
SURGICAL INFECTIONS
(2023)
Article
Medicine, General & Internal
Rebecca Wyse, Stephen Smith, Alison Zucca, Kristy Fakes, Elise Mansfield, Sally-Ann Johnston, Sancha Robinson, Christopher Oldmeadow, Penny Reeves, Mariko L. Carey, Grace Norton, Rob W. Sanson-Fisher
Summary: This study aims to evaluate the effectiveness of the RecoverEsupport digital health intervention in reducing the hospital length of stay for patients undergoing colorectal cancer surgery. The intervention consists of a website and automatic prompts to support patients to adhere to the ERAS recommendations. The findings of the study will be disseminated through peer-reviewed publications and conference presentations.
Article
Gastroenterology & Hepatology
Raquel Cameron, Marjorie M. Walker, Michael Jones, Guy D. Eslick, Simon Keely, Peter Pockney, Carolina C. Cosentino, Nicholas J. Talley
Summary: This study examined the changes of eosinophils and other immune cells in the mucosa of colonic diverticula through quantitative histology. The results showed a significant increase in eosinophil counts at the base and neck of the diverticula. These findings provide new clues for understanding the role of eosinophils and chronic inflammation in the pathophysiology of colonic diverticulosis.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Medicine, General & Internal
Pragya Ajitsaria, Natalie Lott, Angela Baker, Jeanette Lacey, Monique Magnusson, Jeanene Lizbeth Douglas, Paul Healey, Eileen Tan-Gore, Stuart Szwec, Daniel Barker, Simon Deeming, Meredith Tavener, Steve Smith, Jon Gani, John Attia
Summary: Shared decision-making is becoming the gold standard of care for high-risk surgery patients in Australia. This study proposes a novel multidisciplinary shared decision-making model and evaluates its impact on decisional conflict and patient outcomes. The findings will be disseminated through conferences and research journals.
Review
Surgery
Jacob Hampton, Sean S. W. Park, Kerrin Palazzi, Christopher Oldmeadow, Rosemary Carroll, John Attia, Stephen R. Smith
Summary: The study found that chlorhexidine/alcohol (CHA) is the most effective method for preventing deep and superficial surgical site infections, while poviodine/water (PVIW) is the least effective. There was a significant increase in infection odds in the PVIW group compared to the CHA group. There were no significant differences between CHA and PVIA, or CHW and PVIW.
ANZ JOURNAL OF SURGERY
(2022)