Article
Neurosciences
Manabu Yoshimura, Hiroshi Kurumadani, Junya Hirata, Katsutoshi Senoo, Kozo Hanayama, Toru Sunagawa, Kosuke Uchida, Akio Gofuku, Kenji Sato
Summary: This case study describes the effect of virtual reality training on severe, long-term phantom limb pain and upper limb activity on the amputated side. The study found that virtual reality training can reduce pain intensity and increase upper limb activity, possibly by promoting reintegration of the sensory-motor loop.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Elisabetta Ambron, Laurel J. Buxbaum, Alexander Miller, Harrison Stoll, Katherine J. Kuchenbecker, H. Branch Coslett
Summary: Immersive VR activities can reduce phantom limb pain in subjects with lower-limb amputation. Both treatments, one without leg movements and one with leg motions, were successful in reducing PLP by 28% and 39.6% respectively.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Psychology, Multidisciplinary
Taima Alrimy, Wadee Alhalabi, Areej A. Malibari, Fatma Salih Alzahrani, Sharifah Alrajhi, Mohammed Alhalabi, Hunter G. Hoffman
Summary: This study investigates the effectiveness of desktop VR in reducing just noticeable pressure pain in children aged 2-10. The results show that VR significantly reduces pain sensitivity in children, especially in the age group of 2-5.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Rehabilitation
Kalter Hali, Marc A. Manzo, Robert Koucheki, Jay S. Wunder, Richard J. Jenkinson, Amanda L. Mayo, Peter C. Ferguson, Johnathan R. Lex
Summary: The research summarizes the effectiveness of virtual reality (VR) therapy for the management of phantom limb pain (PLP). The findings suggest that VR therapy can significantly reduce PLP, and combining it with tactile stimulation leads to better outcomes. However, the low quality of studies, heterogeneity in subject population and intervention type, and lack of long-term relief data make it difficult to draw definitive conclusions.
DISABILITY AND REHABILITATION
(2023)
Article
Medicine, General & Internal
Taima Alrimy, Wadee Alhalabi, Areej Malibari, Fatma Alzahrani, Sharifah Alrajhi, Ayman Yamani, Halah Ahmed, Amro Abduljawad, Essam Nasser, Samar ALattar, Buthinah Alharby, Hasna Khalid, Mohammed Alhalabi, Hunter G. Hoffman, Keira P. Mason
Summary: Although most scald burn injuries involve children under six, there is limited research on the use of VR in this age group due to the challenges of using head mounted displays on young children. A clinical pilot study was conducted to measure the analgesic effectiveness of a new desktop VR system in children under six during burn wound care. The study found that VR significantly reduced the children's pain and anxiety during burn wound care, as measured by nurse's ratings, observational scales, and parent reports.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
A. Musters, A. S. Vandevenne, A. Franx, M. M. L. H. Wassen
Summary: This study examines the use of VR in labor and its impact on women's experiences. The results show that VR can significantly reduce labor pain and most women are satisfied with its application. These findings contribute to the development of a potential non-pharmacological tool to reduce labor pain.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Psychiatry
Nnamdi Orakpo, Ulrick Vieux, Cristian Castro-Nunez
Summary: Neurofeedback therapy, utilizing EEG as a non-pharmacological intervention, has been used for various conditions since the 1970s. The fusion of Virtual Reality and NFB technologies (VR-NFB) has shown sustained analgesia in centralized pain syndromes, demonstrating the potential of neuromodulation in multimodal pain management.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Health Care Sciences & Services
Claire Terzulli, Meggane Melchior, Laurent Goffin, Sylvain Faisan, Coralie Gianesini, Denis Graff, Andre Dufour, Edouard Laroche, Chloe Chauvin, Pierrick Poisbeau
Summary: The results of this study indicate that virtual reality hypnosis (VRH) can increase heat pain thresholds and affect autonomic functions among healthy volunteers. As a nonpharmacological intervention, VRH has a positive effect on acute experimental heat pain.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Anesthesiology
Jingwei Li, Haoyu Yang, Yian Xiao, Xu Liu, Bingjie Ma, Ke Ma, Li Hu, Xuejing Lu
Summary: This study conducted three experiments to explore the analgesic effect of virtual reality scenes in healthy adult volunteers and found that distinct neural mechanisms are responsible for the pain-relieving effects of virtual reality. These findings contribute to a better understanding of the analgesic benefits of virtual reality and its neural electrophysiological correlates.
BRITISH JOURNAL OF ANAESTHESIA
(2023)
Review
Clinical Neurology
Hunter R. Schone, Chris Baker, Joel Katz, Lone Nikolajsen, Katleho Limakatso, Herta Flor, Tamar R. Makin
Summary: Phantom limb pain (PLP) is a common experience for individuals who have undergone limb amputation, but its characteristics vary greatly. The lack of reliable data has made it challenging to understand the mechanisms of PLP and find effective treatments. However, recent research provides an opportunity to re-examine our assumptions about PLP and its treatments. This review aims to generate consensus on the best ways to study and treat PLP, addressing conceptual and methodological challenges and offering potential solutions. The hope is that a critical evaluation of foundational knowledge will lead to more informed decisions in testing interventions and guide the development of new PLP treatments.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Article
Multidisciplinary Sciences
Gaia Risso, Greta Preatoni, Giacomo Valle, Michele Marazzi, Noelle Moana Bracher, Stanisa Raspopovic
Summary: The multisensory integration of signals plays a crucial role in developing a clear percept of the environment and body. Lower-limb amputees often face challenges in integrating multisensory signals, leading to pain and distorted phantom limb perception. However, a multisensory framework combining virtual reality and electro-cutaneous stimulation can effectively improve sensory perception and reduce phantom limb distortions.
Article
Neurosciences
Xue Deng, Chuyao Jian, Qinglu Yang, Naifu Jiang, Zhaoyin Huang, Shaofeng Zhao
Summary: This study investigated the analgesic effect of different virtual reality interactive modes using functional near-infrared spectroscopy (fNIRS). It found that both the active mode and motor imagery (MI) mode had a larger analgesic effect compared to the passive mode. The activated cortical regions involved motor and cognitive functions.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Clinical Neurology
Jacob Boomgaardt, Kovosh Dastan, Tiffany Chan, Ashley Shilling, Alaa Abd-Elsayed, Lynn Kohan
Summary: Phantom limb pain is a common and challenging condition with no consensus on optimal management and varying clinical responses to available treatments.
JOURNAL OF PAIN RESEARCH
(2022)
Article
Anesthesiology
Brian M. Ilfeld, Bahareh Khatibi, Kamal Maheshwari, Sarah J. Madison, Wael Ali Sakr Esa, Edward R. Mariano, Michael L. Kent, Steven Hanling, Daniel Sessler, James C. Eisenach, Steven P. Cohen, Edward J. Mascha, Chao Ma, Jennifer A. Padwal, Alparslan Turan
Summary: The study found that a 6-day continuous peripheral nerve block can reduce phantom limb pain and improve physical and emotional dysfunction in patients for at least 1 month. Patients who received local anesthesia showed better improvement in overall impression of change and reduction in pain-induced physical and emotional dysfunction, but not in depression scores.
Article
Clinical Neurology
Jasmine Tian Ho, Peter Krummenacher, Marte Roel Lesur, Gianluca Saetta, Bigna Lenggenhager
Summary: The study demonstrates that a virtual placebo treatment can produce placebo analgesia comparable to that of a physical placebo, indicating that administration of a placebo does not require physical interaction with the body.