Article
Biochemical Research Methods
Sina Nejati, Jiangshan Wang, Ulisses Heredia-Rivera, Sotoudeh Sedaghat, Ian Woodhouse, Jay S. Johnson, Mohit Verma, Rahim Rahimi
Summary: A battery-free smart capsule has been designed to target sample inflammatory biomarkers in the small intestine, providing a non-invasive method to differentiate types of inflammatory bowel disease. This innovative technology offers a promising solution for improving IBD diagnosis and treatment strategies by assessing inflammation biomarkers throughout the digestive tract.
Review
Gastroenterology & Hepatology
Itaru Iwama, Ryusuke Nambu, Yoshiko Nakayama
Summary: Capsule endoscopy (CE) and balloon-assisted enteroscopy (BAE) are essential tools for diagnosing and managing small bowel diseases in both children and adults. However, there are differences in the indications for use between these two cohorts, with age and weight playing a significant role in decision making for pediatric cases.
DIGESTIVE ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Gabriel Rahmi, Franck Cholet, Marianne Gaudric, Jerome Filippi, Clotilde Duburque, Slim Bramli, Vincent Quentin, Zarrin Alavi, Emmanuel Nowak, Jean Christophe Saurin, Christophe Cellier, Lucille Queneherve
Summary: This study compared different bowel preparation methods for small bowel capsule endoscopy (SBCE) and found that bowel cleansing improved the quality of SBCE but did not improve the diagnostic yield for patients with suspected small bowel bleeding (SBB).
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Partha Pal, Manu Tandan, Sujay Kulkarni, Palle Manohar Reddy, Mohan Ramchandani, Anuradha Sekaran, Mahesh G. Shetty, Pradeep Rebala, G. Rao, D. Nageshwar Reddy
Summary: This study retrospectively evaluated SBD patients undergoing IOE over the past 15 years, showing high overall diagnostic and therapeutic yields, with IOE playing an important role in guiding therapy and changing management. The low rates of rebleeding and mortality suggest the definitive role of IOE in carefully selected SBD patients in the post-VCE/DAE era.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Medicine, General & Internal
Fintan O'Hara, Deirdre McNamara
Summary: Small bowel capsule endoscopy (SBCE) has revolutionized the diagnosis of small bowel pathology by offering a non-invasive and well-tolerated procedure. However, there are still uncertainties in technical aspects, such as incomplete examinations, poor imaging quality, and the risk of capsule retention, which hinders its clinical utility.
Review
Medicine, General & Internal
Ana-Maria Singeap, Catalin Sfarti, Horia Minea, Stefan Chiriac, Tudor Cuciureanu, Robert Nastasa, Carol Stanciu, Anca Trifan
Summary: The synergy between capsule endoscopy and enteroscopy offers great potential for exploring and treating small bowel conditions. The right selection of exploration method is crucial for optimal results.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Lijuan Qian, Yijie Gu, Lu Zheng, Tingting Xia
Summary: In this study, the clinical data of 134 cases of CE and 109 cases of DBE were retrospectively analyzed. The results showed that DBE had a higher disease diagnostic rate and suspected intestinal bleeding rate than CE, but required a longer examination time, had a higher incidence of adverse reactions, and a lower examination tolerance than CE.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Article
Biology
Maria Manuela Estevinho, Rolando Pinho, Adelia Rodrigues, Ana Ponte, Joao Correia, Pedro Mesquita, Teresa Freitas, Manuel Perucho
Summary: Although users have reported subjective differences between capsule endoscopy devices, there is limited research comparing their visualization quality and diagnostic yield. This study compared two widely used systems (Mirocam (R) MC1600 and OMOM (R) HD) and found differences in small bowel cleanliness and diagnostic yield.
Editorial Material
Medicine, General & Internal
Daniel H. Havlichek, Amrit K. Kamboj, Cadman L. Leggett
Summary: This article reviews the indications, modalities, and differential diagnoses of small bowel bleeding, helping clinicians understand common causes, evaluation methods, and management approaches.
MAYO CLINIC PROCEEDINGS
(2022)
Review
Medicine, General & Internal
Yu Sasaki, Yasuhiko Abe, Naoko Mizumoto, Eiki Nomura, Yoshiyuki Ueno
Summary: Eosinophilic gastroenteritis (EoGE) is a rare digestive disorder characterized by eosinophilic infiltration in the stomach and intestines. The endoscopic findings of EoGE in the small intestine are not well understood, but this literature review identified common findings such as redness, villous atrophy, erosion, ulceration, edema, and stenosis. These findings contribute to the development of EoGE practice.
Article
Medicine, General & Internal
Juho Mattila, Teppo Stenholm, Eliisa Loyttyniemi, Jukka Koffert
Summary: The aim of this study was to find predictive markers for clinically significant small bowel Crohn's disease without the need for small bowel capsule endoscopy. The results indicated that fecal calprotectin, serum albumin, and erythrocyte sedimentation rate were significantly different between patients diagnosed with Crohn's disease and those without. A CECDAI score of 3 could serve as a reasonable cutoff value for small bowel Crohn's disease. Follow-up with fecal calprotectin before small bowel capsule endoscopy may be appropriate for patients without endoscopic ileitis, negative imaging results, and fecal calprotectin levels below 50 ug/g.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Gastroenterology & Hepatology
Marco Pennazio, Emanuele Rondonotti, Rinaldo Pellicano, Pablo Cortegoso Valdivia
Summary: SBCE, introduced nearly 20 years ago, has become an essential tool for studying the small bowel, providing high-quality images and limited invasivity. Despite the lack of direct therapeutic intervention, SBCE plays a key role in diagnosing various conditions and the introduction of cutting-edge technologies like AI is expected to improve its efficiency.
MINERVA GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Vitor Macedo Silva, Tiago Lima Capela, Marta Freitas, Rui Sousa Magalhaes, Catia Arieira, Sofia Xavier, Pedro Boal Carvalho, Bruno Rosa, Maria Joao Moreira, Jose Cotter
Summary: SB-CLEAR is a novel and reproducible grading score for evaluating the quality of small bowel preparation in capsule endoscopy (CE). It has demonstrated excellent inter-observer agreement and may serve as a valuable tool, along with CC-CLEAR, for standardizing the reporting of bowel preparation quality in CE.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Multidisciplinary Sciences
Dong Jun Oh, Youngbae Hwang, Ji Hyung Nam, Yun Jeong Lim
Summary: This study compared the small bowel cleanliness scores of immediate small bowel capsule endoscopy (SBCE) after colonoscopy with SBCE alone. The results showed no difference in small bowel cleanliness between the two groups, and better colon preparation resulted in higher small bowel cleanliness scores. Therefore, immediate SBCE after colonoscopy can adequately maintain small bowel cleanliness.
SCIENTIFIC REPORTS
(2022)
Review
Automation & Control Systems
Yang Liu, Jiyuan Tian, Luigi Manfredi, Benjamin S. Terry, Shyam Prasad, Imdadur Rahman, Wojciech Marlicz, Anastasios Koulaouzidis
Summary: This paper provides a comprehensive review of the anatomy and physiology of the small intestine and discusses the application of capsule endoscopy in examining the surface lining of the small intestine. The paper also summarizes theoretical and practical studies on intestinal motor activities and discusses mathematical modeling and experimental research on capsule endoscopy in the small intestine. Finally, the paper identifies the requirements for improving current work and provides expectations for future research in this field.