期刊
DIGESTIVE DISEASES AND SCIENCES
卷 54, 期 11, 页码 2497-2502出版社
SPRINGER
DOI: 10.1007/s10620-008-0653-8
关键词
Colonic neoplasm; Occult blood; Colonoscopy; Follow-up studies
资金
- NIH [T32 DK007568-17, DK002926-07]
- VA HSR&D Career Development Award [CDA03-174]
There is no guideline defining the optimal time from a positive screening fecal occult blood test to follow-up colonoscopy. We reviewed records of 231 consecutive primary care patients who received a colonoscopy within 18 months of a positive fecal occult blood test. We examined the relationship between time to colonoscopy and risk of neoplasia on colonoscopy using a logistic regression analysis adjusting for potential confounders such as age, race, and gender. The mean time to colonoscopy was 236 days. Longer time to colonoscopy (OR = 1.10, P = 0.01) and older age (OR 1.04, P = 0.01) were associated with higher odds of neoplasia. The association of time with advanced neoplasia was positive, but not statistically significant (OR 1.07, P = 0.14). In this study, a longer interval to colonoscopy after fecal occult blood test was associated with an increased risk of neoplasia. Determining the optimal interval for follow-up is desirable and will require larger studies.
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