Article
Gastroenterology & Hepatology
Szu-Min Peng, Wen-Feng Hsu, Ying-Wei Wang, Li-Ju Lin, Amy Ming-Fang Yen, Li-Sheng Chen, Yi-Chia Lee, Ming-Shiang Wu, Tony Hsiu-Hsi Chen, Han-Mo Chiu
Summary: A study in the Taiwanese Colorectal Cancer Screening Program found that subjects with negative colonoscopy after positive FIT who received subsequent FIT screening had a significantly lower risk of incident CRC, suggesting that scheduling subsequent FIT is important in reducing the risk of missed neoplasms and incident CRC in a national FIT screening program.
Article
Oncology
Zhenwei Zhang, Eric Ganguly, Krunal Patel, Sonja Dawsey, Jacob Bledsoe, Michelle Yang
Summary: Patients with sporadic hyperplastic polyps (HPs) have an increased risk of developing metachronous colorectal cancer (CRC). Historical HPs were reclassified into sessile serrated adenomas (SSAs) or true HPs based on the 2010 and 2019 WHO criteria. The risk of developing metachronous CRC was significantly higher in patients with SSAs and HPs compared to the control group.
AMERICAN JOURNAL OF CANCER RESEARCH
(2023)
Article
Gastroenterology & Hepatology
Jasmin Zessner-Spitzenberg, Lena Jiricka, Elisabeth Waldmann, Lisa -Maria Rockenbauer, Jeremy Cook, Anna Hinterberger, Barbara Majcher, Aleksandra Szymanska, Arno Asaturi, Michael Trauner, Monika Ferlitsch
Summary: A retrospective study with 316,001 individuals revealed that polyps sized 10-20mm and high-grade dysplasia are significantly associated with post-colonoscopy colorectal cancer (PCCRC) mortality. Patients with polyps <10mm and without high-grade dysplasia have significantly lower PCCRC mortality compared to the general population, while those with polyps >10mm or with high-grade dysplasia do not have this advantage.
GASTROINTESTINAL ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Yunyang Deng, Hanyue Ding, Junjie Huang, Martin Chi Sang Wong
Summary: This study aimed to evaluate the cost-effectiveness of different colonoscopy intervals among average-risk (5 vs 10 years) and high-risk (1 vs 3 years) southern Chinese populations. The findings showed that a 10-year interval was more cost-effective for average-risk individuals, while a 3-year interval was more cost-effective for high-risk subjects. These findings can help determine the optimal colonoscopy interval for average-risk and high-risk patients.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Gastroenterology & Hepatology
Fumiaki Ishibashi, Sho Suzuki, Mizuki Nagai, Kentaro Mochida, Tetsuo Morishita
Summary: Resection of adenomatous colorectal polyps has been proven to reduce mortality from colorectal cancer. Cold snare polypectomy (CSP) is a simpler and safer method for the resection of colorectal polyps smaller than 10mm, with advantages in shortening procedure time, reducing bleeding risk, and lowering treatment costs compared to conventional methods. This review summarizes previous studies on the efficacy and safety of CSP, as well as discusses potential expansions of its indications and optimal treatments for recurrent lesions.
DIGESTIVE ENDOSCOPY
(2023)
Review
Gastroenterology & Hepatology
Douglas K. Rex
Summary: Many quality indicators have been proposed for colonoscopy, with emphasis on adenoma detection rate, cecal intubation rate, screening and surveillance intervals. Bowel preparation efficacy and polyp resection skills are emerging as potential key indicators. This review provides an update on performance indicators for colonoscopy quality.
GASTROENTEROLOGY REPORT
(2023)
Article
Gastroenterology & Hepatology
Elisabeth Waldmann, Andreas A. Kammerlander, Irina Gessl, Daniela Penz, Barbara Majcher, Anna Hinterberger, Michael Bretthauer, Michael H. Trauner, Monika Ferlitsch
Summary: The study found that high-quality colonoscopy is associated with a lower risk of CRC death, with the impact of ADR being strongest for individuals with high-risk adenomas.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Carla J. Gargallo-Puyuelo, Angel Lanas, Patricia Carrera-Lasfuentes, Angel Ferrandez, Enrique Quintero, Marta Carrillo, Inmaculada Alonso-Abreu, Maria Asuncion Garcia-Gonzalez
Summary: Epidemiological studies suggest that having a first-degree relative with colorectal cancer (CRC) increases the risk of developing the disease. This study found significant differences in genotype distribution of CRC risk-related SNPs between first-degree relatives of CRC patients and individuals with no family history of CRC. Genotyping of CRC risk variants in first-degree relatives of CRC patients could help identify individuals at risk who may benefit from increased surveillance and CRC screening programs.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Henriette C. Jodal, Dagmar Klotz, Magnhild Herfindal, Ishita Barua, Petter Tag, Lise M. Helsingen, Erle Refsum, Oyvind Holme, Hans-Olov Adami, Michael Bretthauer, Mette Kalager, Magnus Loberg
Summary: A study found that women who had adenomas removed had an increased risk of colorectal cancer death, while men had a reduced risk compared to the general population. Sex-specific surveillance recommendations after adenoma removal should be considered.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Gastroenterology & Hepatology
Mingyang Song, Louise Emilsson, Rolf Hultcrantz, Bjorn Roelstraete, Jonas F. Ludvigsson
Summary: The study found that a normal colonoscopic biopsy is associated with lower colorectal cancer incidence and mortality, lasting for at least 20 years of follow-up. The results suggest that the screening interval after a normal colonoscopy could potentially be longer than the typically recommended 10 years.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
David Beaton, Iosif Beintaris, Matthew D. Rutter
Summary: This study accurately reviewed PCCRC cases at a local level using WEO recommendations, finding almost perfect agreement in the most plausible explanation for almost all cases and substantial consistency in interval/non-interval categorization. The high proportion of non-interval type B PCCRCs suggests that better adherence to recommended surveillance intervals could prevent a significant number of PCCRCs.
Article
Medicine, General & Internal
Markus Dines Knudsen, Kai Wang, Liang Wang, Georgios Polychronidis, Paula Berstad, Kana Wu, Xiaosheng He, Dong Hang, Zhe Fang, Shuji Ogino, Andrew T. Chan, Edward Giovannucci, Molin Wang, Mingyang Song
Summary: This study developed an effective risk stratification tool for predicting post-polypectomy colorectal cancer (PPCRC) based on three population-based cohorts and validated the tool in a clinical cohort. By collecting detailed data on demographics, endoscopic history, polyp features, and lifestyle factors, the researchers developed an 11-predictor risk score for PPCRC, which can guide tailored colonoscopy surveillance strategies.
Article
Gastroenterology & Hepatology
Timothy O'Sullivan, David Tate, Mayenaaz Sidhu, Sunil Gupta, James Elhindi, Karen Byth, Oliver Cronin, Anthony Whitfield, Ana Craciun, Rajvinder Singh, Gregor Brown, Spiro Raftopoulos, Luke Hourigan, Alan Moss, Amir Klein, Steven Heitman, Stephen Williams, Eric Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study investigated the relationship between large nonpedunculated colorectal polyps (LNPCPs) and synchronous colonic LNPCPs, revealing that 6.9% of LNPCPs had synchronous lesions with a greater than 4-fold increased risk for non-granular LNPCPs.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Oncology
Kenechukwu Chudy-Onwugaje, Wen-Yi Huang, L. Joseph Su, Mark P. Purdue, Christine C. Johnson, Lingxiao Wang, Hormuzd A. Katki, Kathryn Hughes Barry, Sonja I. Berndt
Summary: In this study, a beneficial role for both aspirin and ibuprofen in preventing advanced adenoma and curbing progression to recurrence and cancer among older adults was observed during long-term follow-up.
Article
Gastroenterology & Hepatology
Henriette C. Jodal, Paulina Wieszczy-Szczepanik, Dagmar Klotz, Magnhild Herfindal, Ishita Barua, Petter Tag, Lise M. Helsingen, Erle Refsum, Oyvind Holme, Hans-Olov Adami, Michael Bretthauer, Mette Kalager, Magnus Loberg
Summary: By comparing three different adenoma classification systems, we found that using the ESGE 2020 and novel risk classifications can substantially reduce resources needed for colonoscopy surveillance after adenoma removal.