期刊
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
卷 78, 期 4, 页码 368-372出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2013.12.019
关键词
Dengue; Rapid test; SD Bioline Dengue Duo
资金
- El Coyol
- Anastasio Iturralde
- 21 de Abril
- Hospital Regional de Alta Especialidad de Veracruz, Servicios de Salud de Veracruz
- Fondo Mixto CONACyT-Gobierno del estado de Veracruz [109270, 128001]
- Fundacion de Educacion Superior Empresa (FESE) [34450]
In this study, we evaluated the performance of a rapid test, the SD BIOLINE Dengue Duo (SD BDD) kit, with a panel of serum samples from 310 Mexican patients with diagnosis of dengue infection previously confirmed by reference enzyme-linked immunosorbent assay tests. Eighty-seven negative samples from other febrile illnesses were included as controls. The SD BDD showed an overall sensitivity of 90.65% and specificity of 89.66%. No statistically significant differences were found in the sensitivity of the SD BDD kit compared between primary or secondary infections (87.05% versus 93.57%, respectively, P = 0.0761) and dengue fever or dengue hemorrhagic fever cases (90.77% versus 89.74%, respectively, P = 0.7716). However, a higher sensitivity in the acute phase of dengue infection was found compared with the convalescent phase (93.03% versus 81.82%, respectively, P = 0.0089). These results indicate that the SD BDD kit is a useful tool to diagnose dengue infections, both in primary or secondary infections and mainly during the acute phase. (C) 2014 Elsevier Inc. All rights reserved.
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