期刊
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
卷 76, 期 3, 页码 396-398出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2013.03.026
关键词
E. coli; O25b-ST131; CTX-M-15; UTIs; Community isolates; PMQR genes
资金
- CONACyT (Mexican Council for Science and Technology) [136339, 130224]
Escherichia coli is a common uropathogen causing community-acquired urinary tract infections (UTIs). Out of 4735 E. coli community-acquired UTIs, 10.2% were extended spectrum beta-lactamases (ESBL)-producing. The identified ESBL types were CTX-M-15 (96.4%), SHV-2a (3%); and TLA-1 (14 Of the isolates, 94.6% tested positive for plasmid-mediated quinolone resistance (PMQR) genes (aac(6')-lb-cr[92.1%] and qepA1 [%] and for qnr-determinants [3.5%]): E. coli O25b-ST131 was identified in 25% of the isolates that harbor a non-conjugative 160-kb plasmid (IncFIA) containing the CTX-M-15, and all of these isolates were found to contain PMQR genes. This work can be useful in modeling the potential impact that may have on community-acquired UTIs in Mexico. (C) 2013 Elsevier Inc. All rights reserved.
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