期刊
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
卷 28, 期 5-6, 页码 579-587出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/jpem-2014-0116
关键词
arterial pressure; cardiovascular diseases; carotid intima-media thickness; child; obesity
资金
- Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ) [E-26/110.485/2010]
Background: Early exposure to cardiovascular risk factors creates a chronic inflammatory state that could damage the endothelium followed by thickening of the carotid intima-media. Objective: To investigate the association of cardiovascular risk factors and thickening of the carotid intima. Subjects/Methods: Media in prepubertal children. In this cross-sectional study, carotid intima-media thickness (cIMT) and cardiovascular risk factors were assessed in 129 prepubertal children aged from 5 to 10 year. Association was assessed by simple and multivariate logistic regression analyses. Results: In simple logistic regression analyses, body mass index (BMI) z-score, waist circumference, and systolic blood pressure (SBP) were positively associated with increased left, right, and average cIMT, whereas diastolic blood pressure was positively associated only with increased left and average cIMT (p < 0.05). In multivariate logistic regression analyses increased left cIMT was positively associated to BMI z-score and SBP, and increased average cIMT was only positively associated to SBP (p < 0.05). Conclusions: BMI z-score and SBP were the strongest risk factors for increased cIMT.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据