Adipose tissue is inflamed in NAFLD due to obesity but not in NAFLD due to genetic variation in PNPLA3

Effect of short-term carbohydrate overfeeding and long-term weight loss on liver fat in overweight humans

(2012) Ksenia Sevastianova et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Anti-inflammatory and anti-atherogenic properties of adiponectin

(2012) Koji Ohashi et al.   BIOCHIMIE

Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase

(2012) Manju Kumari et al.   Cell Metabolism

Adiponectin: mechanistic insights and clinical implications

(2012) A. T. Turer et al.   DIABETOLOGIA

Chronic overexpression of PNPLA3I148M in mouse liver causes hepatic steatosis

(2012) John Zhong Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Changes in the Prevalence of the Most Common Causes of Chronic Liver Diseases in the United States From 1988 to 2008

(2011) Zobair M. Younossi et al.   Clinical Gastroenterology and Hepatology

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Twist1 in Human White Adipose Tissue and Obesity

(2010) Amanda T. Pettersson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Possible Inflammatory Role of Twist1 in Human White Adipocytes

(2009) A. T. Pettersson et al.   DIABETES

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

Prediction of Non-Alcoholic Fatty Liver Disease and Liver Fat Using Metabolic and Genetic Factors

(2009) Anna Kotronen et al.   GASTROENTEROLOGY

Obesity, Inflammation, and Insulin Resistance – A Mini-Review

(2009) Maximilian Zeyda et al.   GERONTOLOGY

Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization

(2009) Juichi Fukushima et al.   HEPATOLOGY RESEARCH

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adiponectin Promotes Macrophage Polarization toward an Anti-inflammatory Phenotype

(2009) Koji Ohashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin regulation of MCP-1 in human adipose tissue of obese and lean women

(2008) Jukka Westerbacka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased Liver Fat, Impaired Insulin Clearance, and Hepatic and Adipose Tissue Insulin Resistance in Type 2 Diabetes

(2008) Anna Kotronen et al.   GASTROENTEROLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS

Fatty Liver

(2007) Anna Kotronen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY