Review
Biochemistry & Molecular Biology
Cristina Rey-Renones, Jose Miguel Baena-Diez, Isabel Aguilar-Palacio, Cristina Miquel, Maria Grau
Summary: Individuals with type 2 diabetes are at higher risk for developing and dying from cancer, possibly due to metabolic abnormalities such as obesity. Understanding this link can aid in designing personalized preventive strategies.
Article
Endocrinology & Metabolism
Emma J. J. Bouman, Joline W. J. Beulens, Nicolette R. R. den Braver, Marieke T. T. Blom, Sharon Remmelzwaal, Petra J. M. Elders, Femke Rutters
Summary: This study assessed the associations between social jet lag and glycemic and metabolic control in people with type 2 diabetes. The results showed that high social jet lag was associated with higher blood glucose and blood pressure in working people, and lower blood glucose, blood pressure, and higher BMI in retired people. However, the prospective associations were not significant.
Article
Cardiac & Cardiovascular Systems
Christine Gyldenkerne, Martin Bodtker Mortensen, Johnny Kahlert, Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Henrik Toft Sorensen, Reimar Wernich Thomsen, Michael Maeng
Summary: Newly diagnosed type 2 diabetes mellitus significantly increases the risk of cardiovascular disease in patients, especially among younger individuals. Compared to the general population, individuals with type 2 diabetes have a significantly higher 10-year risk of developing cardiovascular events, occurring at least 12 years earlier.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Nelson Wang, Katie Harris, Pavel Hamet, Stephen Harrap, Giuseppe Mancia, Neil Poulter, Bryan Williams, Sophia Zoungas, Mark Woodward, John Chalmers, Anthony Rodgers
Summary: The study found that cumulative systolic blood pressure load was associated with an increased risk of cardiovascular events and death in patients with type 2 diabetes, and provided better prediction compared to traditional blood pressure measures.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Endocrinology & Metabolism
Edward J. Boyko, Leila R. Zelnick, Barbara H. Braffett, Rodica Pop-Busui, Catherine C. Cowie, Gayle M. Lorenzi, Rose Gubitosi-Klug, Bernard Zinman, Ian H. de Boer
Summary: Intensive glycemic control reduces the risk of diabetic foot ulcers, which is an important precursor to lower-extremity amputations in type 1 diabetes patients.
Article
Endocrinology & Metabolism
Edward J. Boyko, Leila R. Zelnick, Barbara H. Braffett, Rodica Pop-Busui, Catherine C. Cowie, Gayle M. Lorenzi, Rose Gubitosi-Klug, Bernard Zinman, Ian H. de Boer
Summary: The study demonstrates that early intensive glycemic control significantly reduces the risk of diabetic foot ulcers in type 1 diabetes patients, which is the most important antecedent in causing lower-extremity amputations.
Review
Cardiac & Cardiovascular Systems
Satyam Suman, Anupam Biswas, Neveen Kohaf, Chhaya Singh, Riya Johns, Pravalika Jakkula, Natasha Hastings
Summary: Diabetes and heart disease are prevalent conditions with a significant global burden. Understanding their relationship is crucial for effective management and prevention strategies. Recent research has established a strong correlation between diabetes and various aspects of cardiovascular health. Mechanisms such as insulin resistance, inflammation, and oxidative stress contribute to the interplay between these two conditions. Early detection, risk assessment, lifestyle modifications, and targeted therapies are important in managing both conditions and improving patient outcomes. Continued research and awareness are vital to mitigating the impact of the diabetes-heart disease connection.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Endocrinology & Metabolism
Bang Zheng, Bowen Su, Geraint Price, Ioanna Tzoulaki, Sara Ahmadi-Abhari, Lefkos Middleton
Summary: Type 2 diabetes is a known risk factor for dementia, with higher or unstable HbA(1c) levels and the presence of diabetic complications increasing the risk of dementia among patients with diabetes. Effective management of glycemia may play a significant role in preserving cognitive health in older adults with diabetes.
Review
Public, Environmental & Occupational Health
Julie E. Lucero, Yvette Roubideaux
Summary: American Indians and Alaska Natives have high rates of type 2 diabetes, which requires both individual and community efforts, as well as supportive policies. The Special Diabetes Program for Indians has achieved significant outcomes in addressing the epidemic of diabetes in AI/AN groups and provides lessons for other populations.
ANNUAL REVIEW OF PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Malini Pires, Sanjit Shaha, Carina King, Joanna Morrison, Tasmin Nahar, Naveed Ahmed, Hannah Maria Jennings, Kohenour Akter, Hassan Haghparast-Bidgoli, A. K. Azad Khan, Anthony Costello, Abdul Kuddus, Kishwar Azad, Edward Fottrell
Summary: This study demonstrates that participatory learning and action (PLA) has a significant impact in reducing intermediate hyperglycemia and type 2 diabetes, with effects observed across all age, gender, and wealth strata. Meanwhile, mHealth interventions appear to be more effective in targeting younger populations.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2022)
Review
Public, Environmental & Occupational Health
Ruth Ndjaboue, Gerard Ngueta, Charlotte Rochefort-Brihay, Sasha Delorme, Daniel Guay, Noah Ivers, Baiju R. Shah, Sharon E. Straus, Catherine Yu, Sandrine Comeau, Imen Farhat, Charles Racine, Olivia Drescher, Holly O. Witteman
Summary: This study provides a comprehensive review of existing prediction models for complications of diabetes, revealing key gaps and limitations, such as the lack of research on complications that are important to patients but underrepresented, and insufficient focus on minority racial groups and adolescent patients. The study suggests that future research should address these gaps and consistently report relevant statistics.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2022)
Article
Geriatrics & Gerontology
T. Norris, W. Johnson, R. Cooper, S. M. Pinto Pereira
Summary: A study found a relationship between diabetes and grip strength decline in mid-to-late adulthood, but no association between diabetes status and different trajectories of grip strength decline. This study is important for understanding the impact of diabetes status on grip strength changes and predicting future diabetes prevalence.
Article
Nutrition & Dietetics
Allie S. Carew, Rania A. Mekary, Susan Kirkland, Olga Theou, Ferhan Siddiqi, Robin Urquhart, Michelle George, Chris Blanchard, Mary L. Biggs, Luc Djousse, Kenneth J. Mukamal, Leah E. Cahill
Summary: This study aimed to assess the relationship between breakfast frequency and timing and T2DM risk in older adults and found that a later daily first eating occasion time was associated with a lower risk of T2DM, particularly in participants with impaired fasting glucose at baseline.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Kimberly A. Bertrand, Katie M. O'Brien, Lauren B. Wright, Julie R. Palmer, William J. Blot, A. Heather Eliassen, Lynn Rosenberg, Sven Sandin, Deirdre Tobias, Elisabete Weiderpass, Wei Zheng, Anthony J. Swerdlow, Minouk J. Schoemaker, Hazel B. Nichols, Dale P. Sandler
Summary: The history of gestational diabetes mellitus (GDM) is not a risk factor for breast cancer in young women. The well-established protective effect of parity on the risk of ER-positive breast cancer persists even for pregnancies complicated by GDM.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Endocrinology & Metabolism
Dong-Hwa Lee, Bumhee Yang, Seonhye Gu, Eung-Gook Kim, Youlim Kim, Hyung Koo Kang, Yeong Hun Choe, Hyun Jeong Jeon, Seungyong Park, Hyun Lee
Summary: This study investigated the yearly trend of influenza vaccination and factors associated with being unvaccinated for influenza in subjects with diabetes over the past decade. The results showed that the prevalence of influenza vaccination in subjects with diabetes tended to increase every year, reaching almost 60% in 2019. Younger age, males, smoking, low-income status, high education level, and poor glycemic control were associated with being unvaccinated.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Immunology
Yang Qu, Andrea Weinstein, Zheng Wang, Yu Cheng, Lawrence Kingsley, Andrew Levine, Eileen Martin, Cynthia Munro, Ann B. Ragin, Leah H. Rubin, Ned W. Sacktor, Eric C. Seaberg, James T. Becker
Summary: The initiation of combination antiretroviral therapy (cART) does not alter the trajectory of cognitive performance in HIV+ men, and cognitive function prior to cART is predictive of postcART function. Cognitive dysfunction in HIV-infected men persists and is not affected by cART in those who had impairment before starting therapy. In addition, motor function declines faster in infected men who were unimpaired prior to cART.
Letter
Medicine, General & Internal
Elisabetta Patorno, Phyo T. Htoo, Robert J. Glynn, Sebastian Schneeweiss, Deborah J. Wexler, Ajinkya Pawar, Lily G. Bessette, Kristyn Chin, BrendanM. Everett, Seoyoung C. Kim
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Clinical Neurology
Ricardo Bruna, David Lopez-Sanz, Fernando Maestu, Ann D. Cohen, Anto Bagic, Ted Huppert, Tae Kim, Rebecca E. Roush, Betz Snitz, James T. Becker
Summary: This study investigated the mechanisms behind Alzheimer's disease and found that patients with amnestic MCI showed a slowing of brain activity, which was not observed in individuals without subjective complaints. This raises interesting questions about this particular group of individuals and the underlying brain mechanisms behind their cognitive impairment.
CLINICAL EEG AND NEUROSCIENCE
(2023)
Article
Mathematical & Computational Biology
Zheng Wang, Zi Wang, Lingyun Lyu, Yu Cheng, Eric C. Seaberg, Samantha A. Molsberry, Ann Ragin, James T. Becker
Summary: In this study, a method for identifying cognitive impairment by using the difference of consecutive LMNC test statistics is proposed. Frequency modeling is used to predict the number of assessments for each participant, and a simple correction method is adopted to control the family-wise error rate. The method effectively controls the error rate in both simulation and real data.
STATISTICS IN MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Chloe Sarnowski, Matthew P. Conomos, Ramachandran S. Vasan, James B. Meigs, Josee Dupuis, Ching-Ti Liu, Aaron Leong
Summary: The effects of genetic burden on obesity risk and cardiovascular disease differ based on birth year, with individuals born after 1960 being more strongly affected. This suggests that the impact of genetics on obesity and cardiovascular risks may be amplified in the increasingly obesogenic environment.
CIRCULATION-GENOMIC AND PRECISION MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Eric J. Brandt, Dariush Mozaffarian, Cindy W. Leung, Seth A. Berkowitz, Venkatesh L. Murthy
Summary: Poor nutrition is the main cause of poor health, high healthcare expenditure, and decreased productivity globally. Social determinants of health, such as food insecurity and nutrition insecurity, influence cardiometabolic diseases. This article focuses on distinguishing between food insecurity and nutrition insecurity, providing an overview of their concepts, measurement, prevalence, and links to health disparities. The discussions here contribute to future research and action to address the negative consequences of food and nutrition insecurity.
CIRCULATION RESEARCH
(2023)
Article
Urology & Nephrology
Edouard L. L. Fu, Elvira D'Andrea, Deborah J. Wexler, Elisabetta Patorno, Julie M. Paik
Summary: In US patients with CKD and type 2 diabetes receiving routine care, the use of SGLT2i was associated with higher risks of genital infections and potentially lower limb amputations and nonvertebral fractures.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Letter
Health Care Sciences & Services
Seth A. Berkowitz, Sanjay Basu, Janel Hanmer
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Seth A. Berkowitz, Deepak Palakshappa
Summary: Background research shows that income is highly important for health, but there is often misunderstanding about income distribution and its relationship to poverty risk. This study provides a structural account of income distribution and poverty risk in the U.S., focusing on the roles individuals inhabit in relation to the factor payment system. The findings suggest that roles other than paid laborer and household composition are associated with greater poverty risk, highlighting the importance of income support policies for those unable to engage in paid labor.
Article
Nutrition & Dietetics
Janaki D. Vakharia, Tanayott Thaweethai, Paul Licht, Deborah J. Wexler, Linda M. Delahanty
Summary: The study identified the modifiable psychological and behavioral factors associated with weight loss. Autonomous motivation, self-efficacy in diet and exercise, dietary self-regulation, and improvement in depressive symptoms were found to be the most important factors in achieving weight loss. These findings provide valuable insights for the design and delivery of lifestyle intervention programs.
JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS
(2023)
Article
Public, Environmental & Occupational Health
Seth A. Berkowitz, Gaurav Dave, Atheendar S. Venkataramani
Summary: The design of the federal Earned Income Tax Credit (EITC) creates an income support gap for low-income workers whose health limits their ability to work, which is not compensated by other government benefits. Filling this gap is an important public health goal.
SSM-POPULATION HEALTH
(2023)
Article
Health Care Sciences & Services
Seth A. Berkowitz, Connor Drake, Elena Byhoff
Summary: This study aimed to determine whether a country's social policy configuration (welfare state regime) is associated with food insecurity risk. The study found that countries with social democratic and corporatist regimes have lower food insecurity risk compared to countries with liberal regimes. This suggests a strong association between social policy configuration and food insecurity risk.
INTERNATIONAL JOURNAL OF SOCIAL DETERMINANTS OF HEALTH AND HEALTH SERVICES
(2023)
Meeting Abstract
Geriatrics & Gerontology
Jennie Dorris, Heather DiCicco, James Becker, Juleen Rodakowski
INNOVATION IN AGING
(2022)
Article
Oncology
Maria Stamou, Christopher Chen, Seth A. Wander, Jeffrey G. Supko, Dejan Juric, Aditya Bardia, Deborah J. Wexler
JCO PRECISION ONCOLOGY
(2022)
Article
Mathematical & Computational Biology
Zheng Wang, Yu Cheng, Eric C. Seaberg, James T. Becker
Summary: This study extends the application of net reclassification improvement (NRI) and integrated discrimination improvement (IDI) indices to competing risk outcomes, using cumulative incidence functions and inverse probability weighting. Various competing risk models are considered and estimation methods for NRI and IDI are presented. The proposed inferential procedures perform well according to simulations.