Depletion of homeodomain-interacting protein kinase 3 impairs insulin secretion and glucose tolerance in mice

Drosophila homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling

(2011) S. Swarup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Homeodomain-interacting protein kinase 2 (HIPK2) targets β-catenin for phosphorylation and proteasomal degradation

(2010) Eun-A Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization

(2010) Rong An et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of TCF3 by Wnt-Dependent Phosphorylation during Vertebrate Axis Specification

(2010) Hiroki Hikasa et al.   DEVELOPMENTAL CELL

Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

(2010) Y. Liu et al.   DIABETOLOGIA

Involvement of the Hipk family in regulation of eyeball size, lens formation and retinal morphogenesis

(2010) Toshihiro Inoue et al.   FEBS LETTERS

Runx2Trans-Activation Mediated by the Msx2-Interacting Nuclear Target Requires Homeodomain Interacting Protein Kinase-3

(2010) Oscar L. Sierra et al.   MOLECULAR ENDOCRINOLOGY

Pathophysiological aspects of Wnt-signaling in endocrine disease

(2009) Sven Schinner et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Modulation of the β-Catenin Signaling Pathway by the Dishevelled-Associated Protein Hipk1

(2009) Sarah H. Louie et al.   PLoS One

The Emerging Genetic Architecture of Type 2 Diabetes

(2008) Alessandro Doria et al.   Cell Metabolism

Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of  -catenin/Arm and stimulation of target gene expression

(2008) W. Lee et al.   DEVELOPMENT

Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation

(2008) Z. Liu et al.   DIABETOLOGIA

The WNT signalling pathway and diabetes mellitus

(2008) T. Jin   DIABETOLOGIA

The Homeodomain-Interacting Protein Kinase 2 Regulates Insulin Promoter Factor-1/Pancreatic Duodenal Homeobox-1 Transcriptional Activity

(2008) Marie-Josée Boucher et al.   ENDOCRINOLOGY

Wnt signaling: relevance to β-cell biology and diabetes

(2008) Hannah J. Welters et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

(2008) Katsuya Tanabe et al.   PLOS BIOLOGY