mRNA of the pro-apoptotic gene BBC3 serves as a molecular marker for TNF-α-induced islet damage in humans

p53 Up-regulated Modulator of Apoptosis (PUMA) Activation Contributes to Pancreatic β-Cell Apoptosis Induced by Proinflammatory Cytokines and Endoplasmic Reticulum Stress

(2010) Esteban N. Gurzov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P38α-Selective Mitogen-Activated Protein Kinase Inhibitor for Improvement of Cultured Human Islet Recovery

(2010) Keiko Omori et al.   PANCREAS

Microassay for Glucose-Induced Preproinsulin mRNA Expression to Assess Islet Functional Potency for Islet Transplantation

(2010) Keiko Omori et al.   TRANSPLANTATION

Quantitative Assessment of β-Cell Apoptosis and Cell Composition of Isolated, Undisrupted Human Islets by Laser Scanning Cytometry

(2010) Ivan Todorov et al.   TRANSPLANTATION

PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis

(2009) P Wang et al.   CELL DEATH AND DIFFERENTIATION

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES

Etanercept Treatment in Children With New-Onset Type 1 Diabetes: Pilot randomized, placebo-controlled, double-blind study

(2009) L. Mastrandrea et al.   DIABETES CARE

PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

(2009) Q Sun et al.   ONCOGENE

Improvement of Canine Islet Yield by Donor Pancreas Infusion With a p38MAPK Inhibitor

(2009) Taihei Ito et al.   TRANSPLANTATION

Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor-Induced Apoptosis of Pancreatic  -Cells

(2008) M. D. McKenzie et al.   DIABETES

Ex vivo simulation of IgG Fc and T-cell receptor functions: An application to inflammatory bowel disease

(2008) Masato Mitsuhashi et al.   INFLAMMATORY BOWEL DISEASES

Tumour necrosis factor-α-induced glucose-stimulated insulin secretion inhibition in INS-1 cells is ascribed to a reduction of the glucose-stimulated Ca2+ influx

(2008) Hyo-Eun Kim et al.   JOURNAL OF ENDOCRINOLOGY

Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia

(2008) Kuniyasu Niizuma et al.   STROKE