Article
Endocrinology & Metabolism
Emmanuel Quaye, Shaji Chacko, Stephanie T. Chung, Robert J. Brychta, Kong Y. Chen, Rebecca J. Brown
Summary: This study demonstrates that gluconeogenesis accounts for a significant portion of energy expenditure in patients with insulin resistance, potentially one-third of resting energy expenditure. Prediction equations may underestimate caloric needs in these individuals.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Neurosciences
Brenda Jeng, Katie L. J. Cederberg, Byron Lai, Jeffer E. Sasaki, Marcas M. Bamman, Robert W. Motl
Summary: The study showed a strong association between wrist-based activity counts and energy expenditure for both persons with PD and controls, with significantly different cut-points for quantifying time spent in MVPA between the two groups.
Article
Pediatrics
Carmen Matey-Rodriguez, Susana Lopez-Ortiz, Saul Penin-Grandes, Jose Pinto-Fraga, Pedro L. Valenzuela, Monica Pico, Carmen Fiuza-Luces, Simone Lista, Alejandro Lucia, Alejandro Santos-Lozano
Summary: This study aimed to analyze the accuracy of Evenson cut-points for estimating moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior (SB) in children and adolescents with disabilities, as well as to define new equations for estimating energy expenditure (EE) in this population, particularly in those with cerebral palsy (CP). Specific GT3X+ cut-points were also defined for estimating MVPA in individuals with CP. The results indicate that using specific ActiGraph GT3X+ cut-points is accurate for estimating MVPA levels in children and adolescents with disabilities, especially those with CP, at least in laboratory conditions.
Article
Multidisciplinary Sciences
Karin Bammann, Nicola K. Thomson, Birte Marie Albrecht, Duncan S. Buchan, Chris Easton
Summary: The study provides placement-specific accelerometer cut-points for determining physical activity intensity in older adults, and compares the validity of these cut-points for different physical activities. However, the derived cut-points did not outperform published ones, indicating the need for further research and innovative approaches to improve internal and external validity of research results.
Article
Physiology
Eric D. Queathem, Maggie Fitzgerald, Rebecca Welly, Candace C. Rowles, Kylie Schaller, Shahad Bukhary, Christopher P. P. Baines, R. Scott Rector, Jaume Padilla, Camila Manrique-Acevedo, Dennis B. Lubahn, Victoria J. Vieira-Potter
Summary: Dysfunction of white adipose tissue (WAT) is a predictor of cardiometabolic disease, and current therapeutics targeting adipocytes are not effective. This study found that estrogen receptor (ER) beta may enhance the response of WAT to B3AR agonists. Understanding the role of ER beta in adipocyte metabolism could have important clinical applications.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Haochong Liu, Qian Li, Yiting Li, Yubo Wang, Yaling Huang, Dapeng Bao, Haoyang Liu, Yixiong Cui
Summary: The purpose of this study was to determine the validity and reliability of a scientific research device, BG2, which combines heart rate variability with an acceleration sensor, for estimating time spent in different intensity zones during free-living activities. The results showed that BG2 estimated physical activity more accurately than Bouchard, especially in moderate to vigorous physical activity. The findings suggest that BG2 is a valid and reliable tool for assessing activity levels in free-living conditions.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Billy Langlet, Fannie Vestermark, Josefin Stolt, Modjtaba Zandian, Per Sodersten, Cecilia Bergh
Summary: Individuals with Anorexia Nervosa are often described as restless, hyperactive and having disturbed sleep. The study aimed to quantify the physical activity and sleep behavior of anorexia nervosa patients and to increase result reproducibility and generalisability. Most patients spent most of their time inactive at the beginning of treatment and failed to meet sleep recommendations.
Article
Endocrinology & Metabolism
Rongya Tao, Oliver Stohr, Caixia Wang, Wei Qiu, Kyle D. Copps, Morris F. White
Summary: This study found that disruption of hepatic insulin signaling can reduce adipose mass and increase energy expenditure in mice, preventing obesity. Moreover, a protein called Fst produced by the liver was found to regulate energy expenditure through its effects on muscles, revealing the important communication between the liver and muscles in controlling energy balance and obesity.
MOLECULAR METABOLISM
(2023)
Article
Nutrition & Dietetics
Javier T. Gonzalez, Alan M. Batterham, Greg Atkinson, Dylan Thompson
Summary: The idea of increasing physical activity directly adding to total energy expenditure (TEE) in humans is challenged by the energy constrained hypothesis. Evidence supporting this hypothesis is limited due to various methodological issues, and future studies should address these limitations by using randomized controlled trials. The available evidence suggests that increasing physical activity mostly has an additive effect on TEE, although some energy remains unaccounted for, and the degree of energy balance may further moderate this effect.
ADVANCES IN NUTRITION
(2023)
Article
Nutrition & Dietetics
Annaliese Widmer, Margaret G. Mercante, Heidi J. Silver
Summary: This study aimed to determine the contribution of cardiometabolic biomarkers to the variation in resting energy expenditure (REE) in individuals with different body mass index (BMI) categories and to assess their contribution in predicting REE based on glycemic and metabolic syndrome status. The results showed that the TG/HDL ratio is an independent predictor of REE. Calculating the TG/HDL ratio can help healthcare providers identify patients with impaired lipid metabolism and optimize REE estimation for weight and disease management goals.
Article
Multidisciplinary Sciences
Benedikte Western, Ingrid Demmelmaier, Ingvild Vistad, Bjorge Herman Hansen, Andreas Stenling, Hege Berg Henriksen, Karin Nordin, Rune Blomhoff, Sveinung Berntsen
Summary: The aim of this study was to determine the minimum number of monitoring days required for reliable estimates of different physical activity (PA) intensities in cancer survivors. Results showed that two monitoring days were needed for reliable estimates of light PA, three monitoring days were needed for moderate and moderate-to-vigorous PA. Reliable estimates for vigorous PA could not be obtained for the overall sample, but were obtained for breast cancer survivors. Shorter monitoring periods with wearable devices may provide reliable estimates and reduce participant burden.
Article
Nutrition & Dietetics
Benjamin T. Bikman, Kim J. Shimy, Caroline M. Apovian, S. Yu, Erin R. Saito, Chase M. Walton, Cara B. Ebbeling, David S. Ludwig
Summary: A high-carbohydrate diet may decrease the oxygen flux of adipocyte mitochondria, potentially affecting energy expenditure and fat deposition.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Physiology
Nadia Elshareif, Emily Gornick, Chaitanya K. Gavini, Gregory Aubert, Virginie Mansuy-Aubert
Summary: This study investigated the long-term effects of Streptozotocin (STZ) on metabolic, cardiac, and somatosensory function in mice fed a Western diet (WD) of high fat, sucrose, and cholesterol. The findings revealed that STZ exacerbated dysfunction in glucose homeostasis and impaired insulin signaling in WD-fed mice. Furthermore, both groups of mice exhibited cardiac autonomic neuropathy and symptoms of neuropathic pain.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Nutrition & Dietetics
Prasangi Dabare, Pujitha Wickramasinghe, Indu Waidyatilaka, Sarita Devi, Anura V. V. Kurpad, Dulani Samaranayake, Maduka de Lanerolle-Dias, Rajitha Wickremasinghe, Andrew P. P. Hills, Pulani Lanerolle
Summary: This study aimed to develop a regression equation to predict physical activity energy expenditure (PAEE) using accelerometry. Children aged 11-13 years were recruited and randomly assigned to validation (n = 54) and cross-validation (n = 25) groups. The final prediction equation (PAEE = [0.001CPM] - 0.112) accounted for 70.6% of the variance and was found to be valid for use in Sri Lankan children.
Article
Health Care Sciences & Services
Yingying Hao, Xiao-Kai Ma, Zheng Zhu, Zhen-Bo Cao
Summary: The study aimed to determine the validity of 11 commercially available wrist-wearable activity devices for monitoring total steps and total 24-hour total energy expenditure in healthy adolescents under simulated free-living conditions, with the conclusion that the Bong 2s had the best accuracy for estimating TEE and total steps. Further research is needed to examine the validity of these devices in different types of physical activities under real-world conditions.
JMIR MHEALTH AND UHEALTH
(2021)
Article
Endocrinology & Metabolism
Tessa Strain, Paddy C. Dempsey, Katrien Wijndaele, Stephen J. Sharp, Nicola Kerrison, Tomas I. Gonzales, Chunxiao Li, Eleanor Wheeler, Claudia Langenberg, Soren Brage, Nick Wareham
Summary: The research found a linear relationship between physical activity energy expenditure (PAEE) and incident type 2 diabetes (T2D), with higher levels of PAEE associated with lower odds of T2D. This association was stronger in men, and weaker in individuals with obesity and higher genetic susceptibility to obesity. For a given level of PAEE, engaging in more moderate-to-vigorous activity was associated with lower odds of T2D.
Article
Public, Environmental & Occupational Health
Andrea Ramirez Varela, Pedro C. Hallal, Juliana Mejia Grueso, Zeljko Pedisic, Deborah Salvo, Anita Nguyen, Bojana Klepac, Adrian Bauman, Katja Siefken, Erica Hinckson, Adewale L. Oyeyemi, Justin Richards, Elena Daniela Salih Khidir, Shigeru Inoue, Shiho Amagasa, Alejandra Jauregui, Marcelo Cozzensa da Silva, I. -Min Lee, Melody Ding, Harold W. Kohl, Ulf Ekelund, Gregory W. Heath, Kenneth E. Powell, Charlie Foster, Aamir Raoof Memon, Abdoulaye Doumbia, Abdul Roof Rather, Abdur Razzaque, Adama Diouf, Adriano Akira Hino, Albertino Damasceno, Alem Deksisa Abebe, Alex Antonio Florindo, Alice Mannocci, Altyn Aringazina, Andrea Backovic Jurican, Andrea Poffet, Andrew Decelis, Angela Carlin, Angelica Enescu, Angelica Maria Ochoa Aviles, Anna Kontsevaya, Annamaria Somhegyi, Anne Vuillemin, Asmaa El Hamdouchi, Asse Amangoua Theodore, Bojan Masanovic, Brigid M. Lynch, Catalina Medina, Cecilia del Campo, Chalchisa Abdeta, Changa Moreways, Chathuranga Ranasinghe, Christina Howitt, Christine Cameron, Danijel Jurakic, David Martinez-Gomez, Dawn Tladi, Debrework Tesfaye Diro, Deepti Adlakha, Dusan Mitic, Dusko Bjelica, Elzbieta Biernat, Enock M. Chisati, Estelle Victoria Lambert, Ester Cerin, Eun-Young Lee, Eva-Maria Riso, Felicia Canete Villalba, Felix Assah, Franjo Lovric, Gerardo A. Araya-Vargas, Giuseppe La Torre, Gloria Isabel Nino Cruz, Gul Baltaci, Haleama Al Sabbah, Hanna Nalecz, Hilde Liisa Nashandi, Hyuntae Park, Ines Revuelta-Sanchez, Jackline Jema Nusurupia, Jaime Leppe Zamora, Jaroslava Kopcakova, Javier Brazo-Sayavera, Jean-Michel Oppert, Jinlei Nie, John C. Spence, John Stewart Bradley, Jorge Mota, Jorge Josef Mitas, Junshi Chen, Kamilah S. Hylton, Karel Fromel, Karen Milton, Katja Borodulin, Keita Amadou Moustapha, Kevin Martinez-Folgar, Lara Nasreddine, Lars Breum Christiansen, Laurent Malisoux, Leapetswe Malete, Lorelie C. Grepo-Jalao, Luciana Zaranza Monteiro, Lyutha K. Al Subhi, Maja Dakskobler, Majed Alnaji, Margarita Claramunt Garro, Maria Hagstromer, Marie H. Murphy, Matthew Mclaughlin, Mercedes Rivera-Morales, Mickey Scheinowitz, Mimoza Shkodra, Monika Piatkowska, Moushumi Chaudhury, Naif Ziyad Alrashdi, Nanette Mutrie, Niamh Murphy, Norhayati Haji Ahmad, Nour A. Obeidat, Nubia Yaneth Ruiz Gomez, Nucharapon Liangruenrom, Oscar Diaz Arnesto, Oscar Flores-Flores, Oscar Incarbone, Oyun Chimeddamba, Pascal Bovet, Pedro Magalhaes, Pekka Jousilahti, Piyawat Katewongsa, Rafael Alexander Leandro Gomez, Rawan Awni Shihab, Reginald Ocansey, Reka Veress, Richard Marine, Rolando Carrizales-Ramos, Saad Younis Saeed, Said El-Ashker, Samuel Green, Sandra Kasoma, Santiago Beretervide, Se-Sergio Baldew, Selby Nichols, Selina Khoo, Seyed Ali Hosseini, Shifalika Goenka, Shima Gholamalishahi, Soewarta Kosen, Sofie Compernolle, Stefan Paul Enescu, Stevo Popovic, Susan Paudel, Susana Andrade, Sylvia Titze, Tamu Davidson, Theogene Dusingizimana, Thomas E. Dorner, Tracy L. Kolbe-Alexander, Tran Thanh Huong, Tracy Huong, Vanphanom Sychareun, Vera Jarevska-Simovska, Viliami Kulikefu Puloka, Vincent Onywera, Wanda Wendel-Vos, Yannis Dionyssiotis, Michael Pratt
Summary: This study aimed to assess the status and trends in physical activity surveillance, policy, and research in 164 countries. The global progress in these three indicators over a 5-year period was found to be modest, with most countries either improving or staying at the same level. Despite a large percentage of the world's population benefiting from some level of physical activity policy, surveillance, and research, there are still significant gaps in support. Europe showed the highest capacity for physical activity promotion, while Africa and low-income countries showed the lowest capacity. Coordinated efforts are needed to reduce inequalities and improve global capacity for physical activity promotion.
JOURNAL OF PHYSICAL ACTIVITY & HEALTH
(2023)
Article
Anthropology
Dirk L. Christensen, Kate Westgate, Lewis Griffiths, Joseph Sironga, Venance P. Maro, Jorn W. Helge, Steen Larsen, Ib C. Bygbjerg, Kaushik L. Ramaiya, Jorgen Jensen, Soren Brage
Summary: This study aimed to objectively quantify the metabolic intensity of traditional jumping-dance activity performed by Maasai men and assess its associations with habitual physical activity and cardiorespiratory fitness. The findings showed that the intensity of jumping-dance activity was moderate, but on average seven times higher than habitual physical activity.
AMERICAN JOURNAL OF HUMAN BIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Johannes Tobias Neumann, Raphael Twerenbold, Francisco Ojeda, Sally Aldous, Brandon Allen, Fred M. Apple, Hugo Babel, Robert Christenson, Louise Cullen, Eleonora Di Carluccio, Dimitrios Doudesis, Ulf M. Ekelund, Evangelos Giannitsis, Jaimi Greenslade, Kenji Inoue, Tomas Jernberg, Peter Kavsak, Till Keller, Kuan Ken Lee, Bertil Lindahl, Thiess Lorenz, Simon Mahler, Nicholas Mills, Arash Mokhtari, William Parsonage, John Pickering, Christopher Pemberton, Christoph Reich, A. Mark Richards, Yader Sandoval, Martin A. Than, Betuel Toprak, Richard Troughton, Andrew Worster, Tanja Zeller, Andreas Ziegler, Stefan Blankenberg, ARTEMIS Study Grp
Summary: Researchers developed a digital tool using machine-learning techniques to estimate the individual probability of myocardial infarction (MI) and validated its discriminative performance in multiple independent cohorts. The tool showed higher efficiency in screening and ruling out MI compared to the current recommended strategy.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Endocrinology & Metabolism
Miguel Adriano Sanchez-Lastra, Ding Ding, Knut Eirik Dalene, Borja del Pozo Cruz, Ulf Ekelund, Jakob Tarp
Summary: This study aimed to determine the age-specific associations between different adiposity measurements and the risk of death. The results showed that obesity was positively associated with mortality risk, with a weaker association observed in older age groups. High levels of obesity were associated with a smaller reduction in risk, and low lean mass was also associated with an increased risk of mortality.
INTERNATIONAL JOURNAL OF OBESITY
(2023)
Article
Sport Sciences
Eero A. Haapala, Anna Widlund, Anna-maija Poikkeus, Rodrigo Antunes Lima, Soren Brage, Pirjo Aunio, Timo A. Lakka
Summary: This study investigated the longitudinal associations between physical activity, motor performance, and academic skills in Finnish primary school children from grade 1 to grade 3. The results showed that better motor performance predicted higher academic skills, while there was no direct or indirect association between physical activity and academic skills. Academic skills in grade 1 did not contribute to physical activity or motor performance.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Correction
Biotechnology & Applied Microbiology
Rosa Lundbye Allesoe, Agnete Troen Lundgaard, Ricardo Hernandez Medina, Alejandro Aguayo-Orozco, Joachim Johansen, Jakob Nybo Nissen, Caroline Brorsson, Gianluca Mazzoni, Lili Niu, Jorge Hernansanz Biel, Cristina Leal Rodriguez, Valentas Brasas, Henry Webel, Michael Eriksen Benros, Anders Gorm Pedersen, Piotr Jaroslaw Chmura, Ulrik Plesner Jacobsen, Andrea Mari, Robert Koivula, Anubha Mahajan, Ana Vinuela, Juan Fernandez Tajes, Sapna Sharma, Mark Haid, Mun-Gwan B. Hong, Petra Musholt, Federico De Masi, Josef Vogt, Helle Krogh Pedersen, Valborg Gudmundsdottir, Angus Jones, Gwen Kennedy, Jimmy Bell, E. Louise Thomas, Gary Frost, Henrik Thomsen, Elizaveta Hansen, Tue Haldor Hansen, Henrik Vestergaard, Mirthe T. Muilwijk, Marieke M. Blom, Leen 't Hart, Francois Pattou, Violeta Raverdy, Soren Brage, Tarja Kokkola, Alison Heggie, Donna McEvoy, Miranda Mourby, Jane Kaye, Andrew Hattersley, Timothy McDonald, Martin Ridderstrale, Mark Walker, Ian N. Forgie, Giuseppe Giordano, Imre Pavo, Hartmut Ruetten, Oluf Pedersen, Torben Hansen, Emmanouil W. Dermitzakis, Paul M. Franks, Jochen Schwenk, Jerzy I. Adamski, Mark McCarthy, Ewan Pearson, Karina Banasik, Simon Rasmussen, Soren Brunak
NATURE BIOTECHNOLOGY
(2023)
Article
Multidisciplinary Sciences
Tomas Gonzales, Justin Jeon, Timothy Lindsay, Kate Westgate, Ignacio Perez-Pozuelo, Stefanie Hollidge, Katrien Wijndaele, Kirsten Rennie, Nita Forouhi, Simon Griffin, Nick Wareham, Soren Brage
Summary: This study evaluates the relationship between resting heart rate (RHR) and cardiorespiratory fitness, finding associations between RHR and fitness, exploring factors that influence this relationship, and demonstrating the utility of RHR for remote population monitoring. The results suggest that RHR is a valid biomarker of cardiorespiratory fitness, and that physical activity and adiposity influence the relationship between RHR and fitness.
Article
Health Care Sciences & Services
Natascha H. Pedersen, Anders Grontved, Jan C. Brond, Niels C. Moller, Kristian T. Larsen, Birgit Debrabant, Sofie Koch, Jens Troelsen, Soren Brage, Jasper Schipperijn, Jacob Hjelmborg, Niels Wedderkopp, Lars B. Christiansen, Peter L. Kristensen
Summary: A new Danish school policy requiring 45 minutes of physical activity daily during school hours was introduced in 2014. This study evaluated the effect of this nationwide policy on physical activity in Danish children and adolescents. The results showed that the policy interrupted the decreasing trend of physical activity during school hours and increased physical activity among students.
LANCET REGIONAL HEALTH-EUROPE
(2023)
Editorial Material
Sport Sciences
Jason M. R. Gill, Timothy J. Chico, Aiden Doherty, Jessilyn Dunn, Ulf Ekelund, Peter T. Katzmarzyk, Karen Milton, Marie H. Murphy, Emmanuel Stamatakis
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
Article
Sport Sciences
Sehrish Naveed, Taisa Sallinen, Aino-Maija Eloranta, Hannamari Skog, Henna Jalkanen, Soren Brage, Ulf Ekelund, Heikki Pentikaeinen, Kai Savonen, Timo A. Lakka, Eero A. Haapala
Summary: In this study, a combined dietary and physical activity intervention in children did not have an effect on cognition. However, improvements in diet quality and participation in organized sports and reading were associated with improved cognition.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Emergency Medicine
Sebastian Herlitz, Joel Ohm, Henrike Habel, Ulf Ekelund, Robin Hofmann, Per Svensson
Summary: In this study, it was found that low income is associated with prolonged emergency department processes, as patients with low income were more likely to be assessed later than recommended and had longer EDLOS. The longer process times may lead to ED crowding and delay in diagnosis and treatment.
JOURNAL OF THE AMERICAN COLLEGE OF EMERGENCY PHYSICIANS OPEN
(2023)
Article
Sport Sciences
Otavio Amaral de Andrade Leao, Thayna Ramos Flores, Jaime Barratt, Andrea Damaso Bertoldi, Marlos Rodrigues Domingues, John Cairney, Ulf Ekelund, Inacio Crochemore-Silva, Gregore Iven Mielke, Pedro Curi Hallal
Summary: Physical activity has a negative association with weight-related growth indicators, and weight-related growth indicators also have a negative impact on physical activity in children under five years of age.
JOURNAL OF SPORTS SCIENCES
(2023)
Article
Public, Environmental & Occupational Health
Arao Belitardo de Oliveira, Peter T. Katzmarzyk, Wagner Silva Dantas, Isabela Judith Martins Bensenor, Alessandra de Carvalho Goulart, Ulf Ekelund
Summary: This study examined the prevalence of leisure-time physical activity and sedentary behavior in Brazilian adults and found that the majority of adults in Brazil are physically inactive and do not meet international recommendations.
EPIDEMIOLOGIA E SERVICOS DE SAUDE
(2023)
Article
Oncology
Emmanuel Stamatakis, Matthew N. Ahmadi, Christine M. Friedenreich, Joanna M. Blodgett, Annemarie Koster, Andreas Holtermann, Andrew Atkin, Vegar Rangul, Lauren B. Sherar, Armando Teixeira-Pinto, Ulf Ekelund, I-Min Lee, Mark Hamer
Summary: This study found that small amounts of vigorous intermittent lifestyle physical activity (VILPA) were associated with a lower risk of incident cancer. Less than 1 minute of VILPA per day was associated with a reduced risk of total cancer and PA-related cancer. The minimal dose of VILPA required for risk reduction was 3.4 minutes per day for total cancer and 3.7 minutes for PA-related cancer.
