期刊
DIABETIC MEDICINE
卷 30, 期 3, 页码 E78-E86出版社
WILEY-BLACKWELL
DOI: 10.1111/dme.12062
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资金
- Competence Network Diabetes mellitus of the German Federal Ministry of Education and Research (BMBF) [01 GI 0815]
- German Federal Ministry of Education and Research (BMBF) [01ZZ0403]
- Ministry for Education, Research, and Cultural Affairs
- Ministry for Social Affairs of the Federal State of Mecklenburg-West Pomerania
- Deutsche Forschungsgemeinschaft as part of the Collaborative Research Center 598
- Wilhelm-Roux Programme of the Martin-Luther-University Halle-Wittenberg
- Ministry of Education and Cultural Affairs of Saxony-Anhalt
- Federal Employment Office
- German Migraine and Headache Society (DMKG)
- Astra Zeneca
- Berlin Chemie
- Boots Healthcare
- Glaxo-Smith-Kline
- McNeil Pharma
- MSD Sharp Dohme
- Pfizer
- German Ministry of Education and Science
- Helmholtz Zentrum Munchen - German Research Center for Environmental Health
- German Federal Ministry of Education and Research
- State of Bavaria
- German Research Foundation from the German Diabetes Center
- German Federal Ministry of Health
- Ministry of School, Science and Research of the State of North-Rhine-Westphalia
Aim Our objective was to test the hypothesis that the prevalence of Type2 diabetes increases with increasing regional deprivation even after controlling for individual socio-economic status. Methods We pooled cross-sectional data from five German population-based studies. The data set contained information on n=11688 study participants (men 50.1%) aged 4574years, of whom 1008 people had prevalent Type2 diabetes (men 56.2%). Logistic multilevel regression was performed to estimate odds ratios (OR) and 95% confidence intervals (CI) for diabetes prevalence. We controlled for sex, age and lifestyle risk factors, individual socio-economic status and regional deprivation, based on a new small-area deprivation measure, the German Index of Multiple Deprivation. Results Adjusted for sex, age, body mass index (BMI), physical activity, smoking status and alcohol consumption, the prevalence of Type2 diabetes showed a stepwise increase in risk with increasing area deprivation [OR1.88 (95%CI 1.163.04) in quintile4 and OR2.14 (95%CI 1.293.55) in quintile5 compared with the least deprived quintile1], even after controlling for individual socio-economic status. Focusing on individual socio-economic status alone, the risk of having diabetes was significantly higher for low compared with medium or high educational level [OR1.46 (95%CI 1.241.71)] and for the lowest compared with the highest income group [OR1.53 (95%CI 1.181.99)]. Conclusion Regional deprivation plays a significant part in the explanation of diabetes prevalence in Germany independently of individual socio-economic status. The results of the present study could help to target public health measures in deprived regions.
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