Review
Health Care Sciences & Services
Hidetaka Hamasaki
Summary: Exercise may have a therapeutic effect on diabetes patients with cardiovascular autonomic neuropathy (CAN), but further research is needed, especially in different patient populations.
Article
Physiology
Shiyue Pan, Emma Karey, Madeline Nieves-Cintron, Yi-Je Chen, Sung Hee Hwang, Bruce D. Hammock, Kent E. Pinkerton, Chao-Yin Chen
Summary: Secondhand smoke exposure significantly affects cardiac autonomic function and blood pressure regulation. The adverse cardiovascular effects of secondhand smoke can be reversed by discontinuing exposure, and inhibiting soluble epoxide hydrolase can prevent these effects.
FRONTIERS IN PHYSIOLOGY
(2023)
Article
Clinical Neurology
Ian M. Greenlund, Jeremy A. Bigalke, Anne L. Tikkanen, John J. Durocher, Carl A. Smoot, Jason R. Carter
Summary: The study found that evening binge alcohol consumption can reduce cardiac vagal tone and baroreflex sensitivity in different sleep stages.
Article
Clinical Neurology
Ian M. Greenlund, Jeremy A. Bigalke, Anne L. Tikkanen, John J. Durocher, Carl A. Smoot, Jason R. Carter
Summary: The study showed that evening binge alcohol consumption negatively affects cardiac vagal tone and baroreflex sensitivity during sleep, providing insights into the potential cardiovascular risks associated with binge drinking.
Article
Neurosciences
Shoou-Jeng Yeh, Chi-Wen Lung, Yih-Kuen Jan, Ben-Yi Liau
Summary: Diabetes is a chronic disease that causes damage to various organs in the body. This study proposes a new method to detect autonomic neuropathy in diabetes patients by analyzing the changes in blood pressure and heart rate. The results show that this method can differentiate between different types of diabetes and uncover hidden changes in blood pressure control.
FRONTIERS IN NEUROSCIENCE
(2022)
Review
Clinical Neurology
Shobi Sivathamboo, Piero Perucca
Summary: Epilepsy is associated with alterations in resting autonomic functions, particularly in HRV, BRS and EDA. HRV abnormalities are most pronounced in temporal lobe epilepsy, Dravet syndrome and drug-resistant epilepsies.
CURRENT OPINION IN NEUROLOGY
(2021)
Article
Behavioral Sciences
S. B. Athira, Pravati Pal, Pradeep P. Nair, Nivedita Nanda, Rajeswari Aghoram
Summary: This study compared the cardiac autonomic function and baroreflex sensitivity in individuals with drug-resistant temporal lobe epilepsy and healthy controls. The results showed that individuals with drug-resistant temporal lobe epilepsy had reduced parasympathetic function, decreased heart rate variability, and impaired blood pressure regulation. These findings suggest an increased risk of sudden unexpected death in epilepsy in this population.
EPILEPSY & BEHAVIOR
(2023)
Article
Clinical Neurology
Ivan Mostak, Nika Visnjic, Anamari Junakovic, Magdalena Krbot Skoric, Mario Habek
Summary: The study aimed to compare the clinical usefulness of alpha- and beta-adrenergic components of the baroreflex sensitivity index with standardized measures of autonomic dysfunction. Results showed that alpha-BRSa had positive correlation with heart rate in the supine position and negative correlation with the adrenergic index, while beta-BRSa had negative correlation with tests for parasympathetic nervous system function. BRSv showed negative correlation with heart rate and blood pressure parameters and positive correlation with heart rate variability parameters.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Endocrinology & Metabolism
Jens Christian Laursen, Kim Katrine Bjerring Clemmensen, Christian Stevns Hansen, Lars Jorge Diaz, Marco Bordino, Per-Henrik Groop, Marie Frimodt-Moller, Luciano Bernardi, Peter Rossing
Summary: Individuals with type 1 diabetes show lower blood oxygen saturation compared to healthy controls, and have a smaller increase in blood oxygen saturation after standing up. Both groups experience a decrease in arm oxygen saturation after standing, with a more significant decrease in individuals with type 1 diabetes.
BMJ OPEN DIABETES RESEARCH & CARE
(2021)
Article
Endocrinology & Metabolism
Junyi Wang, Zihui Xu, Kang Lv, Yingchun Ye, Deng Luo, Li Wan, Fen Zhou, Ailin Yu, Shuo Wang, Jingcheng Liu, Ling Gao
Summary: The study found that declined HRV in T2DM patients is associated with lower CaA levels and worse cardiac function. Serum calcium level can be used as a risk evaluation for declined HRV in T2DM patients, even within the normocalcemic range.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Clara C. Zwack, Rachael McDonald, Ainura Tursunalieva, Amali Cooray, Gavin W. Lambert, Elisabeth A. Lambert
Summary: The study showed that young adults with intellectual disability have autonomic dysfunction and increased cardiovascular risk factors compared to control adults. Autonomic dysfunction was more pronounced in those with severe disability, independent of cardiovascular parameters. Assessment of autonomic nervous system function may provide insight into cardiometabolic disease development in this population.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Neurosciences
Branislav Milovanovic, Vlado Djajic, Dragana Bajic, Aleksandra Djokovic, Tatjana Krajnovic, Sladjana Jovanovic, Antonija Verhaz, Pedja Kovacevic, Miodrag Ostojic
Summary: This study found that autonomic dysfunction, including sympathetic, parasympathetic, or both, may occur in COVID-19 patients in the early phase of infection, with significantly higher proportions in the severe and mild groups compared to healthy controls. Therefore, cardiovascular autonomic neuropathy should be taken into consideration in the assessment of COVID-19 patients.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Cardiac & Cardiovascular Systems
Rachel J. Skow, Nicole A. Garza, Damsara Nandadeva, Brandi Y. Stephens, Alexis N. Wright, Ann-Katrin Grotle, Benjamin E. Young, Paul J. Fadel
Summary: Emerging evidence suggests that COVID-19 may affect cardiac autonomic function, but the limited findings in young adults have been inconclusive. This study found no significant differences in heart rate variability and cardiac baroreflex sensitivity between young adults with persistent symptoms following COVID-19, those who were asymptomatic, and controls who never had COVID-19. However, there were significant relationships between measures of cardiac autonomic function and time since diagnosis, suggesting that COVID-19-related changes in cardiac autonomic function are transient in young, otherwise healthy adults.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2022)
Article
Multidisciplinary Sciences
Thomas Arendt Nielsen, Soren Lundbye-Christensen, Yoanna Krasimirova Dimitrova, Sam Riahi, Birgitte Brock, Asbjorn Mohr Drewes, Christina Brock
Summary: Heart rate variability during tonic cold pain can potentially reveal cardiac autonomic neuropathy in individuals with type 1 diabetes mellitus. Compared to healthy controls, patients with type 1 diabetes mellitus have lower heart rate variability, which is further diminished during exposure to cold pain.
SCIENTIFIC REPORTS
(2023)
Article
Medicine, General & Internal
Monika Zawadka-Kunikowska, Lukasz Rzepinski, Malgorzata Tafil-Klawe, Jacek J. Klawe, Pawel Zalewski, Joanna Slomko
Summary: This study aimed to evaluate the cardiac and autonomic function in patients with myasthenia gravis (MG) and investigate its relationship with disease outcomes. The results showed that MG patients exhibited altered systolic blood pressure variability, reduced heart rate response to deep breathing test, increased sympathovagal balance after tilt, lower baroreflex sensitivity, and decreased hemodynamic parameters compared to controls. Disease severity was found to be associated with diminished vagal tone and increased sympathetic response. Age and sex were the main predictors of hemodynamic parameters. These findings highlight the importance of evaluating autonomic balance in MG patients, especially those at risk for cardiovascular disease.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Marton Fekete, Marton Piroska, Marcell Szily, Mercedesz Erdei, Zsofia Jokkel, Helga Szabo, Levente Littvay, Gyorgy Baffy, Adam Domonkos Tarnoki, David Laszlo Tarnoki
Summary: This study aimed to analyze the heritability of liver fibrosis in asymptomatic adult twins and found that environmental factors played a significant role in the development of NAFLD and liver fibrosis.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
(2021)
Article
Political Science
Cengiz Erisen, Mattia Guidi, Sergio Martini, Selin Toprakkiran, Pierangelo Isernia, Levente Littvay
Summary: Studies on demand-side populism are gaining popularity, with a focus on attitudes and behaviors, but fewer have explored the psychological determinants. Conspiracy beliefs are found to be the primary source of populist attitudes, while the impact of other psychological factors depends more on context. The research highlights the importance of conceptual clarity, careful theorization, and refinement of survey measures.
POLITICAL PSYCHOLOGY
(2021)
Article
Political Science
Gabor Simonovits, Jennifer McCoy, Levente Littvay
Summary: With the global democratic backsliding, the support for leaders who erode democracy is gaining attention. This study proposes a novel survey experimental design to examine the support for democratic norms among citizens when their own party is in power. The findings show a significant degree of democratic hypocrisy among the American public, with increased support for norm-eroding policies when their own party is in power, especially amplified by strong partisan biases and perceived threats from the opposing party.
JOURNAL OF POLITICS
(2022)
Article
Area Studies
Daniel Kovarek, Levente Littvay
Summary: The Hungarian municipal elections in October 2019 provided hope for political forces aiming to overthrow the Fidesz rule. The opposition's success in winning the mayoral seat in Budapest and control over several major cities was facilitated by coordination among opposition parties, electoral innovations, effective messaging, and a Fidesz scandal. The newly elected opposition mayors now face the challenges posed by the COVID-19 pandemic.
EAST EUROPEAN POLITICS
(2022)
Article
Cardiac & Cardiovascular Systems
Zsofia D. Drobni, Marton Kolossvary, Julia Karady, Adam L. Jermendy, Adam D. Tarnoki, David L. Tarnoki, Judit Simon, Balint Szilveszter, Levente Littvay, Szilard Voros, Gyorgy Jermendy, Bela Merkely, Pal Maurovich-Horvat
Summary: This study found that noncalcified plaque volume is mainly influenced by environmental factors, while coronary artery calcification score and calcified plaque volume are more determined by genetics. This emphasizes the importance of early lifestyle interventions in preventing coronary plaque formation.
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Article
Psychology, Multidisciplinary
Francisco D. Fernandez-Martin, Jose L. Arco-Tirado, Elena-Cristina Mitrea, Levente Littvay
Summary: This study evaluates the correlation between parental grit and offspring grit, as well as the moderating role of different parenting behaviors. The results indicate that there is a connection between parental grit and offspring grit, with parenting behaviors playing a moderating role. The study also emphasizes the direct association between various parenting dimensions and grit, particularly the positive relationship with parental control.
CURRENT PSYCHOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Daniel Gyurki, Tamas Horvath, Sara Till, Attila Egri, Csilla Celeng, Gyorgy Paal, Bela Merkely, Pal Maurovich-Horvat, Gabor Halasz
Summary: This study introduces a reduction of the system parameters and a novel calculation method to estimate the patient-specific aortic pressure curve based on radial applanation tonometry. The results show that the aortic pressure curves were reproduced well in different patients.
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2023)
Article
Clinical Neurology
Timo Siepmann, Martin Arndt, Annahita Sedghi, Szabolcs Szatmari Jr, Tamas Horvath, Annamaria Takats, Daniel Bereczki, Mats Leif Moskopp, Sylvia Buchmann, Cornelia Skowronek, Wagner Zago, Warunya Woranush, Razvan Lapusca, Marie Luise H. Weidemann, Christopher Gibbons, Roy Freeman, Heinz Reichmann, Volker Puetz, Kristian Barlinn, Alexandra Pinter, Ben Min-Woo Illigens
Summary: This study characterized autonomic pilomotor and sudomotor skin function in early Parkinson's disease (PD) longitudinally. The results showed that pilomotor function and sympathetic skin response (SSR) were impaired in PD, indicating sympathetic pathophysiology. However, cholinergic sudomotor function and parasympathetic neurocardiac function remained unchanged. This finding suggests that a pilomotor axon-reflex test may be useful for monitoring PD-related pathology.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Multidisciplinary Sciences
Rita Magyar-Stang, Lilla Istvan, Hanga Pal, Borbala Csanyi, Anna Gaal, Zsuzsanna Mihaly, Zsofia Czinege, Peter Sotonyi, Horvath Tamas, Akos Koller, Daniel Bereczki, Illes Kovacs, Robert Debreczeni
Summary: The study investigates the correlation between impaired cerebrovascular reactivity and retinal vessel density in patients with ICA stenosis. The findings suggest a common mechanism of action and highlight the potential of using TCD and OCTA in identifying patients with increased ischemic or other cerebrovascular risks.
Article
Geriatrics & Gerontology
Rita Magyar-Stang, Hanga Pal, Borbala Csanyi, Anna Gaal, Zsuzsanna Mihaly, Zsofia Czinege, Tamas Csipo, Zoltan Ungvari, Peter Sotonyi, Andrea Varga, Tamas Horvath, Daniel Bereczki, Akos Koller, Robert Debreczeni
Summary: Unhealthy vascular aging promotes atherogenesis and can lead to significant internal carotid artery stenosis (CAS) in older adults. This study found that CAS is associated with impaired cerebral vascular reactivity, but there were no significant differences in autoregulatory function or inter-hemispheric blood flow between symptomatic and asymptomatic CAS patients. Anatomically compromised circle of Willis did not significantly affect these parameters.
Article
Political Science
Federico Vegetti, Levente Littvay
Summary: In the last decade, there has been an increase in political protest events in Western democracies, as well as a rise in the diffusion of conspiracy theories in political communication. While most research focuses on the reasons for believing in conspiracies, there is limited study on the political-behavioral implications of such beliefs, particularly their connection to political radicalism. This paper investigates the association between belief in conspiracies and the endorsement of political violence or radical political action, and provides correlational evidence using survey data of US respondents.
ITALIAN POLITICAL SCIENCE REVIEW-RIVISTA ITALIANA DI SCIENZA POLITICA
(2022)
Article
Medicine, General & Internal
Dora Melicher, Anett Illes, Levente Littvay, Adam Domonkos Tarnoki, David Laszlo Tarnoki, Andras Bikov, Laszlo Kunos, Dora Csaban, Edit Iren Buzas, Maria Judit Molnar, Andras Falus
Summary: The study revealed a significant positive association between mtDNA copy number and telomere length, and twins showed similarity in their intraclass correlation coefficients regardless of zygosity, indicating a potentially important role of common environmental factors.
ARCHIVES OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Laszlo Szalontai, Zsofia Jokkel, Tamas Horvath, Bianka Forgo, Ildiko Kalina, Pal Maurovich-Horvat, Philip L. Auyang, M. Mujeeb Zubair, Zsolt Garami, David Laszlo Tarnoki, Adam Domonkos Tarnoki
Summary: The geometry of the vertebrobasilar system contributes to the presence, severity, and laterality of white matter hyperintensities. Basilar artery morphology significantly affects the localization of WMH, particularly in the parietooccipital region. An unequal vertebral artery flow and increased basilar artery curvature may indicate inadequate blood flow and predict cerebrovascular events.
CROATIAN MEDICAL JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
John Whitaker, Julia Karady, Rashed Karim, Catalina Tobon-Gomez, Thomas Fastl, Orod Razeghi, Louisa O'Neill, Marie Decroocq, Steven Williams, Cesare Corrado, Rahul K. Mukherjee, Iain Sim, Daniel O'Hare, Irum Kotadia, Marton Kolossvary, Bela Merkely, Levente Littvay, Adam D. Tarnoki, David L. Tarnoki, Szilard Voros, Reza Razavi, Mark O'Neill, Ronak Rajani, Pal Maurovich Horvat, Steven Niederer
Summary: The study aimed to establish normal ranges for left atrial parameters derived from coronary computed tomographic angiography (CCTA) imaging and identify early markers of pathological remodelling.
IJC HEART & VASCULATURE
(2021)
Article
Medicine, General & Internal
Laszlo Szalontai, Zsofia Jokkel, Tamas Horvath, Marton Piroska, Bianka Forgo, Csaba Olah, Laszlo Kostyal, David L. Tarnoki, Adam D. Tarnoki
Summary: The study found that the diameter, curvature, and tortuosity of the vertebral artery V4 segment were mainly influenced by shared and unshared environmental factors, while the length and volume of the basilar artery showed a moderate genetic influence, and torsion showed no heritability influence.
MEDICINA-LITHUANIA
(2021)
