Article
Endocrinology & Metabolism
Peter Jacob, Laura Potts, Rory H. Maclean, Nicole de Zoysa, Helen Rogers, Linda Gonder-Frederick, Emma L. Smith, Dulmini Kariyawasam, Augustin Brooks, Simon Heller, Elena Toschi, Mike Kendall, Ioannis Bakolis, Pratik Choudhary, Kimberley Goldsmith, Stephanie A. Amiel
Summary: This study describes the baseline emotional, cognitive, and behavioral characteristics of participants in the HARPdoc trial, which focuses on treatment-resistant problematic hypoglycemia. The findings reveal that the participants had high levels of anxiety and depression, and endorsed unhelpful health beliefs regarding hypoglycemia, with low fear of hypoglycemia.
Review
Nursing
Yu Zhang, Shuang Li, Yan Zou, Xiaxin Wu, Yaxin Bi, Lu Zhang, Yuan Yuan, Weijuan Gong, Mark Hayter
Summary: This review highlights the negative impact of fear of hypoglycaemia on quality of life, especially in terms of psychosocial functioning, daily life, and sleep quality. Healthcare providers should pay attention to psychological concerns and quality of life in patients with type 1 diabetes and type 2 diabetes, and evaluate advanced technology for its benefits before implementation.
JOURNAL OF CLINICAL NURSING
(2021)
Article
Endocrinology & Metabolism
Hannah Chatwin, Melanie Broadley, Christel Hendrieckx, Jill Carlton, Simon Heller, Stephanie A. Amiel, Bastiaan de Galan, Rory J. McCrimmon, Ulrik Pedersen-Bjergaard, Frans Pouwer, Jane Speight
Summary: Hypoglycemia has a negative impact on various domains of quality of life for adults with type 1 diabetes, including leisure activities, physical health, ability to keep fit and be active, sleep, emotional well-being, spontaneity, independence, work/studies, and dietary freedom. Psychological factors play a larger role in explaining this negative impact than hypoglycemia frequency and awareness.
JOURNAL OF DIABETES AND ITS COMPLICATIONS
(2023)
Article
Endocrinology & Metabolism
Manon Coolen, Jori Aalders, Melanie Broadley, Henk-Jan Aanstoot, Esther Hartman, Christel Hendrieckx, Giesje Nefs, Frans Pouwer
Summary: The study found that fear of hypoglycaemia was significantly associated with diabetes-specific quality of life in adolescents with type 1 diabetes, while frequency and perceived severity of hypoglycaemia were not.
Review
Endocrinology & Metabolism
Hannah Chatwin, Melanie Broadley, Bastiaan de Galan, Ellen Bazelmans, Jane Speight, Frans Pouwer, Giesje Nefs
Summary: This study aims to summarize and assess the effectiveness of educational and/or behavioural interventions in reducing fear of hypoglycaemia among adults with type 1 diabetes. Systematic searches were conducted and data were synthesized using meta-analyses and narrative synthesis. The results suggest that these interventions can reduce fear of hypoglycaemia, but there is a lack of research on individuals with high fear of hypoglycaemia.
Article
Nursing
Merve Yuksel, Hicran Bektas
Summary: The study found that patients with type 2 diabetes had moderate compliance with treatment and low fear of hypoglycemia. It was also discovered that education, economic status, self-monitoring of blood glucose, physical activity, and education about diabetes were significantly associated with treatment compliance and fear of hypoglycemia in patients with type 2 diabetes.
JOURNAL OF CLINICAL NURSING
(2021)
Review
Nursing
Austin Matus, Kimberly K. Trout, Amy M. Sawyer, Barbara Riegel
Summary: This study reviewed and integrated primary research on the relationship between sleep and hypoglycemia symptom perception in adults with type-1 diabetes. The findings showed that sleep reduces the magnitude of detectable symptoms, affecting individuals' capacity to perceive them accurately, and highlighted the challenging duality of sleep's impact on hypoglycemia symptom perception.
JOURNAL OF ADVANCED NURSING
(2022)
Article
Endocrinology & Metabolism
Alon Liberman, Michal Nevo Shenker, Rachel Bello, Michal Yackobovitch-Gavan, Iris Shachar-Lavie, Malgorzata Wojcik, Anna Starmach, Jerzy B. B. Starzyk, Eirini Kostopoulou, Dionisios Chrysis, Moshe Phillip
Summary: This study aimed to develop and validate a new questionnaire, the Hyperglycaemia Fear Survey - Parent version (FoHyper-P), for measuring fear of hyperglycaemia among parents of children with type 1 diabetes (T1D), and to investigate the correlations between parental fear of hyperglycaemia and objective measures of glycaemic control. The study found significant strong-moderate correlations between FoHyper-P and HFS-P.
Article
Multidisciplinary Sciences
Stephanie A. Amiel, Laura Potts, Kimberley Goldsmith, Peter Jacob, Emma L. Smith, Linda Gonder-Frederick, Simon Heller, Elena Toschi, Augustin Brooks, Dulmini Kariyawasam, Pratik Choudhary, Marietta Stadler, Helen Rogers, Mike Kendall, Nick Sevdalis, Ioannis Bakolis, Nicole de Zoysa
Summary: In this randomized control trial, the authors found that a group programme focusing on changing cognitive barriers to avoiding hypoglycaemia (HARPdoc) does not reduce severe hypoglycaemia more than a programme focusing on behaviors (BGAT) in adults with type 1 diabetes and treatment-resistant impaired awareness of hypoglycaemia (IAH) and severe hypoglycaemia.
NATURE COMMUNICATIONS
(2022)
Article
Endocrinology & Metabolism
Ruth S. Weinstock, Bruce W. Bode, Satish K. Garg, David C. Klonoff, Caroline El Sanadi, W. Blair Geho, Douglas B. Muchmore, Marc S. Penn
Summary: The aim of this study was to investigate whether an increased bolus: basal insulin ratio with liver-targeted bolus insulin would increase bolus insulin usage and decrease hypoglycaemic events. The results showed that liver-targeted bolus insulin safely decreased hypoglycaemic events and symptoms without compromising glucose control.
DIABETES OBESITY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Peter Jacob, Munachiso Nwokolo, Sally M. Cordon, Ian A. Macdonald, Fernando O. Zelaya, Stephanie A. Amiel, Owen O'Daly, Pratik Choudhary
Summary: The study found that during hypoglycemia, diabetes patients with preserved hypoglycemia awareness showed changes in connectivity in the DMN and SN, while patients with impaired awareness exhibited reduced connectivity within the RIFG. These findings suggest that changes in connectivity in the RIFG region may play a key role in impaired hypoglycemia awareness.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Article
Endocrinology & Metabolism
Per G. Hagelqvist, Andreas Andersen, Kaisar B. Maytham, Christine R. Andreasen, Susanne Engberg, Tommi B. Lindhardt, Jens Faber, Jens J. Holst, Julie L. Forman, Ulrik Pedersen-Bjergaard, Filip K. Knop, Tina Vilsboll
Summary: This study aims to compare the effects of exercise-related hypoglycemia and hypoglycemia induced at rest on cardiac repolarisation in patients with type 1 diabetes. The results showed that both scenarios caused prolonged QTc interval and Tpe interval during hypoglycemia, accompanied by increased plasma adrenaline and decreased plasma potassium. During the recovery phase, the hypoglycemia induced at rest group had a longer QTc interval compared to the exercise-related hypoglycemia group. This indicates that both scenarios may increase the risk of ventricular arrhythmias in patients.
DIABETES OBESITY & METABOLISM
(2023)
Review
Medicine, General & Internal
Meryem K. Talbo, Alexandra Katz, Lee Hill, Tricia M. Peters, Jean-Francois Yale, Anne-Sophie Brazeau
Summary: This systematic review and meta-analysis aimed to understand the impact of diabetes technologies on fear of hypoglycaemia (FOH) in type 1 diabetes patients. The results showed that using real-time or intermittently scanned continuous glucose monitors, insulin pumps, or their combinations can reduce FOH levels, particularly those related to the HFS-W subscale.
Article
Endocrinology & Metabolism
Talia A. Hitt, Jennifer A. Hershey, Diana Olivos-Stewart, Emily Forth, Fiona Stuart, Patrik Garren, Jonathan Mitchell, Colin P. Hawkes, Steven M. Willi, Julie M. Gettings
Summary: This study examines the relationship between fear of hypoglycaemia (FOH) and sleep in adolescents with type 1 diabetes (T1D). It also evaluates the influence of continuous glucose monitor (CGM) and insulin pump use on sleep. The results show that worrying about hypoglycaemia is associated with impaired sleep for adolescents with T1D, and the use of diabetes technology has limited effects on sleep outcomes.
Article
Endocrinology & Metabolism
Pierre-Yves Benhamou, Sandrine Lablanche, Anne Vambergue, Maeva Doron, Sylvia Franc, Guillaume Charpentier
Summary: The study compared the efficacy of the closed-loop Diabeloop system with the open-loop predictive low glucose suspend system in patients with highly unstable diabetes. The results showed that the closed-loop system was superior in improving metabolic control.
DIABETES OBESITY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Thomas Danne, Lutz Heinemann, Jan Bolinder
DIABETES TECHNOLOGY & THERAPEUTICS
(2018)
Letter
Endocrinology & Metabolism
Jan Bolinder, Per Oskarsson, Ramiro Antuna, Petronella Geelhoed-Duijvestijn, Jens Kroeger, Raimund Weitgasser
Article
Nursing
Helena Loof, Unn-Britt Johansson
JOURNAL OF CLINICAL NURSING
(2019)
Article
Medicine, General & Internal
Susanne Amsberg, Ingrid Wijk, Fredrik Livheim, Eva Toft, Unn-Britt Johansson, Therese Anderbro
Article
Endocrinology & Metabolism
Thomas Danne, Lutz Heinemann, Jan Bolinder
DIABETES TECHNOLOGY & THERAPEUTICS
(2019)
Article
Health Care Sciences & Services
Maria Svedbo Engstrom, Janeth Leksell, Unn-Britt Johansson, Sixten Borg, Bo Palaszewski, Stefan Franzen, Soffia Gudbjornsdottir, Katarina Eeg-Olofsson
HEALTH AND QUALITY OF LIFE OUTCOMES
(2019)
Article
Endocrinology & Metabolism
Thomas Danne, Lutz Heinemann, Jan Bolinder
DIABETES TECHNOLOGY & THERAPEUTICS
(2020)
Article
Health Care Sciences & Services
Katarina Eeg-Olofsson, Unn-Britt Johansson, Ebba Linder, Janeth Leksell
JOURNAL OF MEDICAL INTERNET RESEARCH
(2020)
Article
Endocrinology & Metabolism
Marcus Lind, Arndis F. Olafsdottir, Irl B. Hirsch, Jan Bolinder, Sofia Dahlqvist, Aldina Pivodic, Jarl Hellman, Magnus Wijkman, Erik Schwarcz, Henrik Albrektsson, Tim Heise, William Polonsky
Summary: The SILVER study demonstrates the long-term benefits of CGM on HbA(1c), hypoglycemia, treatment satisfaction, well-being, and hypoglycemic confidence in people with T1D managed with MDI.
Article
Nursing
Sara Haile, Helena Loof, Unn-Britt Johansson, Anneli Linne, Eva Joelsson-Alm
Summary: This study explores patients' experiences of participating in the FASTIC study after surgical treatment for claudication. The findings indicate that patient participation in follow-up programs is crucial for increasing awareness of one's own health, and patient-professional collaboration in person-centered care is important for maintaining a health-promoting lifestyle.
JOURNAL OF VASCULAR NURSING
(2022)
Article
Health Care Sciences & Services
Kristina Larsson, Maria Hagstromer, Jenny Rossen, Unn-Britt Johansson, Asa Norman
Summary: This study aimed to explore barriers and facilitators perceived by healthcare professionals in Swedish primary care in their work to support persons with metabolic risk factors to increase their physical activity. The findings suggest that barriers and facilitators for supporting patients with metabolic risk factors can be found at several levels within primary care, from individual patient and the healthcare professionals to the organizational level.
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE
(2023)
Article
Surgery
Sara T. Haile, Unn-Britt Johansson, Helena Loof, Anneli Linne, Eva Joelsson-Alm
Summary: The objective of this study was to evaluate the impact of a person centred nurse led follow up programme on health related quality of life, health literacy, and general self efficacy for patients undergoing revascularisation for intermittent claudication. The results showed that the intervention had no significant effect on these factors.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Endocrinology & Metabolism
Ingrid Wijk, Susanne Amsberg, Sissel Andreassen Gleissman, Eva Toft, Therese Anderbro, Unn-Britt Johansson
Summary: This study aimed to describe the experiences of adults with prolonged elevated HbA1c levels in type 1 diabetes (T1D). The findings revealed that living with T1D and high HbA1c levels can be perceived as constraining but manageable. Therefore, a person-centered care approach may be beneficial.
Article
Endocrinology & Metabolism
Marcus Lind, Sergiu-Bogdan Catrina, Neda R. Ekberg, Sofia Gerward, Tariq Halasa, Jarl Hellman, Detlef Hess, Magnus Londahl, Veronica Qvist, Jan Bolinder
Summary: This study analyzed the effects of switching to faster aspart treatment in adults with T1D using continuous glucose monitoring data. The results showed that switching to faster aspart led to improvements in glycemic control without increasing the risk of hypoglycemia.
Review
Health Care Sciences & Services
Julia Bergevi, Susanne Andermo, Yohannes Woldamanuel, Unn-Britt Johansson, Maria Hagstromer, Jenny Rossen
Summary: This study explores users' perceptions of the acceptability, engagement, and usability of eHealth and mHealth services that promote physical activity, healthy diets, or both in the primary or secondary prevention of noncommunicable diseases. The findings indicate that these services should be personalized, dynamic, easily manageable, and reliable to improve adherence to digital health-promoting services.
JMIR HUMAN FACTORS
(2022)