Article
Biology
Sharen Lee, Helen Huang, Teddy Tai Loy Lee, Cheuk To Chung, Oscar Hou In Chou, Keith Sai Kit Leung, Abraham Ka Chung Wai, Wing Tak Wong, Tong Liu, Carlin Chang, Gary Tse
Summary: This study investigated the relationship between the sequence of development of coronary heart disease (CHD), atrial fibrillation (AF), and heart failure (HF) and the risk of all-cause mortality in type 2 diabetes mellitus patients. The results showed that the sequence of comorbidity development affects the risk of all-cause mortality to varying degrees in diabetic patients on different antidiabetic/cardiovascular medications.
Article
Endocrinology & Metabolism
Mei-Hsin Su, Ying-Hsiu Shih, Yen-Feng Lin, Pei-Chun Chen, Chia-Yen Chen, Po-Chang Hsiao, Yi-Jiun Pan, Yu-Li Liu, Shih-Jen Tsai, Po-Hsiu Kuo, Chi-Shin Wu, Yen-Tsung Huang, Shi-Heng Wang
Summary: This study investigates the familial aggregation and shared genetic loading between common psychiatric disorders (such as schizophrenia, major depressive disorder, and bipolar disorder) and type 2 diabetes. The results suggest a familial association between type 2 diabetes and the psychiatric disorders studied, as well as a shared genetic etiology between major depressive disorder and type 2 diabetes.
Article
Endocrinology & Metabolism
Faisal Aziz, Felix Aberer, Othmar Moser, Caren Sourij, Dirk von Lewinski, Susanne Kaser, Berthold Reichardt, Harald Sourij
Summary: This study evaluated the impact of characteristics and comorbidities on hospitalization rate and mortality after influenza-related illness in individuals with diabetes. The results showed that older age, heart failure, renal disease, and Charlson comorbidity index were significant predictors of mortality following hospitalization for influenza-related illness in individuals with diabetes.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
Kalie L. Tommerdahl, Karl Baumgartner, Michal Schafer, Petter Bjornstad, Isabella Melena, Shannon Hegemann, Amy D. Baumgartner, Laura Pyle, Melanie Cree-Green, Uyen Truong, Lorna Browne, Judith G. Regensteiner, Jane E. B. Reusch, Kristen J. Nadeau
Summary: The study evaluated the impact of BMI on cardiovascular and kidney outcomes in youth with T1D and T2D, finding that obese adolescents with T1D have a higher cardiovascular and kidney disease risk profile, similar to youth with T2D.
Article
Medicine, General & Internal
Cristina Gavina, Daniel Seabra Carvalho, Daniel Martinho Dias, Filipa Bernardo, Hugo Martinho, Joao Couceiro, Carla Santos-Araujo, Ricardo Jorge Dinis-Oliveira, Tiago Taveira-Gomes
Summary: The coexistence of heart failure (HF) or chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2D) under 65 years old is associated with increased risk of premature death and non-fatal cardiovascular (CV) events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
Nanna Lindekilde, Stine H. Scheuer, Lars J. Diaz, Katrine H. Rubin, Oleguer Plana-Ripoll, Jan Erik Henriksen, Mathias Lasgaard, Gregers S. Andersen, Frans Pouwer
Summary: This study aimed to investigate the incidence of type 2 diabetes in individuals with psychiatric disorders and found that individuals with a psychiatric disorder, especially younger individuals, had a higher incidence rate of type 2 diabetes.
Article
Computer Science, Information Systems
Diana Barsasella, Srishti Gupta, Shwetambara Malwade, Aminin, Yanti Susanti, Budi Tirmadi, Agus Mutamakin, Jitendra Jonnagaddala, Shabbir Syed-Abdul
Summary: Type 2 diabetes mellitus (T2DM) and hypertension (HTN) are major causes of death globally, with poor treatment leading to increased healthcare utilization and costs. This study used machine learning algorithms to predict length of stay (LoS) and mortality among hospitalized patients in Indonesia, finding that linear regression model best predicted LoS and MLP best predicted mortality. These predictions can inform health policies to reduce disease burden in resource-limited settings.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2021)
Article
Clinical Neurology
Tong Luo, Yun-Feng Tu, Shan Huang, Yuan-Yuan Ma, Qing-Hua Wang, Yan-Jiang Wang, Jun Wang
Summary: This study aimed to investigate the longitudinal impact of type 2 diabetes mellitus (T2DM) on the prodromal and dementia stages of Alzheimer's disease (AD), focusing on diabetes duration and other comorbidities. The study found that a longer duration of T2DM (≥5 years) was significantly associated with an increased risk of incident prodromal AD, but not with the risk of progression to AD dementia. The APOE e4 allele and comorbid coronary artery disease (CAD) further increased the risk of incident prodromal AD in patients with T2DM.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Medicine, General & Internal
Hertzel C. Gerstein, Naveed Sattar, Julio Rosenstock, Chinthanie Ramasundarahettige, Richard Pratley, Renato D. Lopes, Carolyn S. P. Lam, Nardev S. Khurmi, Laura Heenan, Stefano Del Prato, Leanne Dyal, Kelley Branch
Summary: The trial compared the cardiovascular and renal outcomes of weekly injections of efpeglenatide versus a placebo in participants with type 2 diabetes and a history of cardiovascular disease or current kidney disease. The study found that the risk of cardiovascular events was lower with efpeglenatide treatment, and a composite renal outcome event was also reduced.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Geriatrics & Gerontology
Francesca Remelli, Maria Giorgia Ceresini, Caterina Trevisan, Marianna Noale, Stefano Volpato
Summary: This systematic review investigated the prevalence and impact of polypharmacy in older adults with diabetes. The results showed a high prevalence of polypharmacy in this population and its strong association with adverse outcomes, including mortality.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
Article
Oncology
Kelechi Njoku, Heather J. Agnew, Emma J. Crosbie
Summary: This study aimed to investigate the impact of pre-existing type 2 diabetes mellitus (T2DM) on survival outcomes in endometrial cancer. The results showed that women with T2DM had an increased risk of overall mortality, cancer-specific mortality, and recurrence rates compared to those without T2DM.
FRONTIERS IN ONCOLOGY
(2022)
Article
Clinical Neurology
Maria Teresa Alcantara-Garces, Alejandra Monserrat Rodriguez-Ramirez, Ana Cristina Garcia-Ulloa, Sergio Hernandez-Jimenez
Summary: This study aimed to describe the metabolic status and clinical characteristics associated with NPPD in patients with less than five years of T2D diagnosis and explore the role of age in the presentation of psychiatric comorbidities. The results showed that NPPD were frequent comorbidities in the sample, with younger age, female sex, and personal psychiatric history being the most important factors associated with psychiatric comorbidities. Younger subjects had a higher risk for psychiatric disorders and worse metabolic control.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Medicine, General & Internal
Bertram Pitt, Gerasimos Filippatos, Rajiv Agarwal, Stefan D. Anker, George L. Bakris, Peter Rossing, Amer Joseph, Peter Kolkhof, Christina Nowack, Patrick Schloemer, Luis M. Ruilope
Summary: Finerenone therapy improved cardiovascular outcomes in patients with type 2 diabetes and stage 2 to 4 CKD with moderately elevated albuminuria or stage 1 or 2 CKD with severely elevated albuminuria, compared to placebo. The risk of the primary outcome event was significantly lower in the finerenone group, primarily driven by a reduction in hospitalization for heart failure.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Medicine, General & Internal
Ming Gao, Wenrui Lin, Tianqi Ma, Yi Luo, Hejian Xie, Xunjie Cheng, Yongping Bai
Summary: This study compared cardiovascular risks of four different antihypertensive drugs in patients with isolated systolic hypertension (ISH) and type 2 diabetes mellitus (T2DM). The results showed that angiotensin receptor blockers (ARB) reduced the risk of cardiovascular mortality, while other drugs did not have the same effect.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Environmental Sciences
Sandra India-Aldana, Rania Kanchi, Samrachana Adhikari, Priscilla Lopez, Mark D. Schwartz, Brian D. Elbel, Pasquale E. Rummo, Melissa A. Meeker, Gina S. Lovasi, Karen R. Siegel, Yu Chen, Lorna E. Thorpe
Summary: Large-scale longitudinal studies suggest an association between land use environment (LUE) and risk for type 2 diabetes (T2D), but the relationship varies across different community types. Food environment may modify the association between LUE and T2D.
ENVIRONMENTAL RESEARCH
(2022)
Article
Neurosciences
C. E. Dismuke-Greer, M. Gebregziabher, A. L. Byers, D. Taber, N. Axon, K. Yaffe, L. E. Egede
Article
Medicine, General & Internal
Yemisrach A. Tefera, Kinfe G. Bishu, Mulugeta Gebregziabher, Aprill Z. Dawson, Leonard E. Egede
JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
(2019)
Article
Behavioral Sciences
Liza S. Koster, Fortune Sithole, Gregory E. Gilbert, Elpida Artemiou
JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH
(2019)
Article
Nursing
Josephine Kamendat, Beverly W. Dabney, Marilyn McFarland, Gregory E. Gilbert, Kathleen Richards-Weatherby
JOURNAL OF NURSING CARE QUALITY
(2020)
Article
Ethics
Linda D'Appolonia Knecht, Beverly W. Dabney, Lauren E. Cook, Gregory E. Gilbert
Article
Education & Educational Research
Szabolcs Felszeghy, Sanna Pasonen-Seppanen, Ali Koskela, Petteri Nieminen, Kai Harkonen, Kaisa M. A. Paldanius, Sami Gabbouj, Kirsi Ketola, Mikko Hiltunen, Mikael Lundin, Tommi Haapaniemi, Erkko Sointu, Eric B. Bauman, Gregory E. Gilbert, David Morton, Anitta Mahonen
BMC MEDICAL EDUCATION
(2019)
Article
Nursing
Angela B. Samosorn, Gregory E. Gilbert, Eric B. Bauman, Justin Khine, Dee McGonigle
CLINICAL SIMULATION IN NURSING
(2020)
Article
Cardiac & Cardiovascular Systems
Erin R. Weeda, Kinfe G. Bishu, Ralph Ward, R. Neal Axon, David J. Taber, Mulugeta Gebregziabher
BMC CARDIOVASCULAR DISORDERS
(2020)
Article
Pharmacology & Pharmacy
James N. Fleming, Mulugeta Gebregziabher, Aurora Posadas, Zemin Su, John W. McGillicuddy, David J. Taber
Summary: The study found that a pharmacist-led intervention utilizing mHealth technology can effectively reduce tacrolimus intrapatient variability, improving treatment outcomes for kidney transplant recipients. Further prospective studies are needed to confirm the impact of this intervention on long-term clinical outcomes for patients.
AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY
(2021)
Article
Public, Environmental & Occupational Health
Caroline J. Vrana-Diaz, Jeffrey E. Korte, Mulugeta Gebregziabher, Lauren Richey, Anbesaw Selassie, Michael Sweat, Rose Kisa, William Musoke, Harriet Chemusto, Esther Buregyeya, Joseph K. B. Matovu, Rhoda K. Wanyenze
Summary: This study demonstrates the importance of women's negative attitudes towards IPV in increasing male partner's uptake of HST, providing insights for integrating HST into national health care policies.
AJAR-AFRICAN JOURNAL OF AIDS RESEARCH
(2021)
Meeting Abstract
Cardiac & Cardiovascular Systems
Afrah A. Ali, Wan-Tsu Chang, Ali Tabatabai, Melissa B. Pergakis, Camilo A. Gutierrez, Benjamin Neustein, Gregory E. Gilbert, Jamie E. Podell, Gunjan Parikh, Neeraj Badjatia, Melissa Motta, David P. Lerner, Nicholas A. Morris
Article
Health Care Sciences & Services
Ralph Ward, Erin Weeda, David J. Taber, Robert Neal Axon, Mulugeta Gebregziabher
Summary: Veterans experience disproportionate health impacts from the opioid epidemic, with prediction models based on electronic medical record data showing promise in identifying high-risk patients. A modified version of the original STORM model improved risk prediction performance, particularly in accurately identifying patients at risk for overdose and suicide-related events. The new proposed model using mGLMM approach demonstrated significantly better prediction performance in terms of AUC and sensitivity compared to the modified STORM model, indicating its potential for more effectively targeting interventions for at-risk patients.
HEALTH SERVICES AND OUTCOMES RESEARCH METHODOLOGY
(2022)
Article
Public, Environmental & Occupational Health
James F. Phillips, Charlotte M. Roy, Mulugeta Gebregziabher
Summary: The Tigray crisis in Ethiopia shares similarities with the Biafra region during the Nigerian Civil War, both facing starvation, forced displacement, and isolation from commerce due to being surrounded by hostile forces. However, insufficiently integrated relief strategies in Biafra resulted in a slow nutritional recovery process, highlighting the importance of reviewing and learning from past experiences to prevent a recurrence in Tigray. The application of evidence-based relief organization systems could accelerate post-conflict nutritional recovery in Tigray.
GLOBAL HEALTH ACTION
(2022)
Article
Clinical Neurology
Fred S. Sarfo, Bruce Ovbiagele, Mulugeta Gebregziabher, Onoja Akpa, Albert Akpalu, Kolawole Wahab, Godwin Ogbole, Rufus Akinyemi, Reginald Obiako, Morenikeji Komolafe, Lukman Owolabi, Daniel Lackland, Donna Arnett, Hemant Tiwari, Hugh S. Markus, Joshua Akinyemi, Ayodipupo Oguntade, Bimbo Fawale, Abiodun Adeoye, Obiabo Olugbo, Luqman Ogunjimi, Godwin Osaigbovo, Carolyn Jenkins, Ijezie Chukwuonye, Olabamiji Ajose, Lekan Oyinloye, Fedelis Mutiso, Ruth Laryea, Benedict Calys-Tagoe, Abdul Salaam, Ganiyu Amusa, Samuel Olowookere, Chidiebere Imoh, Aliyu Mande, Oyedunni Arulogun, Fakunle Adekunle, Lambert Appiah, Olayemi Balogun, Arti Singh, Osi Adeleye, Okechukwu Ogah, Akintomiwa Makanjuola, Dorcas Owusu, Philip Kolo, Oladimeji Adebayo, Atinuke Agunloye, Vincent Shidali, Moyinoluwalogo Faniyan, Sulaiman Lakoh, Samuel Diala, Henry Iheonye, Chika Efidi, Emmanuel Sanya, Taofiki Sunmonu, Adeseye Akintunde, Mayowa Owolabi
Article
Public, Environmental & Occupational Health
Georgiana Onicescu, Andrew B. Lawson, Jiajia Zhang, Mulugeta Gebregziabher, Kristin Wallace, Jan M. Eberth
SPATIAL AND SPATIO-TEMPORAL EPIDEMIOLOGY
(2019)