Serum bone morphogenetic protein 7, insulin resistance, and insulin secretion in non-diabetic individuals

This study was to explore the relationship of serum BMP7 with insulin secretion and metabolic parameters in non-diabetic individuals. Serum BMP7 concentrations positively correlated with HOMA2-%B (insulin secretion index) and fasting insulin. Our findings suggested that BMP7 may stimulate insulin secretion and improve islet cell function in humans. (C) 2011 Elsevier Ireland Ltd. All rights reserved.