Article
Public, Environmental & Occupational Health
Binur Orazumbekova, Alpamys Issanov, Kuralay Atageldiyeva, Salim Berkinbayev, Gulnara Junusbekova, Laura Danyarova, Zhanmedet Shyman, Akmaral Tashmanova, Antonio Sarria-Santamera
Summary: This study aimed to estimate the prevalence of impaired fasting glucose (IFG), undiagnosed, and prior-diagnosed Type 2 diabetes mellitus (T2DM) in Kazakhstan. The results showed a high prevalence of IFG and a significant proportion of newly diagnosed T2DM in Kazakhstan. The identified risk factors can be used to strengthen the identification of undiagnosed patients and provide preventive or therapeutic interventions to reduce the incidence of T2DM and its complications.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Endocrinology & Metabolism
Kara L. Holloway-Kew, Amelia Betson, Pamela G. Rufus-Membere, James Gaston, Adolfo Diez-Perez, Mark A. Kotowicz, Julie A. Pasco
Summary: This study found that in men, individuals with T2DM had lower bone material strength index (BMSi) compared to those without T2DM, independent of T2DM, while bone mineral density (BMD) and trabecular bone score (TBS) measured by DXA were higher. These results suggest that measures reflecting bone material properties and microarchitecture may be better than BMD in identifying individuals with T2DM at risk of fracture.
Article
Endocrinology & Metabolism
Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Oak-Kee Hong, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
Summary: The status of metabolic abnormalities, including impaired fasting glucose (IFG), can change over time. Using data from the Korean National Health Insurance system, the study found that cumulative exposure to IFG was associated with a higher risk of type 2 diabetes mellitus in a dose-response fashion.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Biochemistry & Molecular Biology
Tina Kalbitzer, Kristina Lobenhofer, Silke Martin, Markus Beck Erlach, Werner Kremer, Hans Robert Kalbitzer
Summary: Type 2 diabetes and its borderline states, impaired fasting glucose and/or glucose tolerance, are associated with dyslipoproteinemia. This study uses NMR spectroscopy to analyze the lipoprotein subclass patterns of patients with different stages of diabetes and investigates the changes in lipoprotein patterns over time. The study found that the lipoprotein subclass distributions were altered in diabetic patients, but the total concentrations of lipoprotein particles produced by the liver were not significantly changed.
LIPIDS IN HEALTH AND DISEASE
(2023)
Review
Clinical Neurology
Yuhan Karida Liu, Susan Ling, Leanna M. W. Lui, Felicia Ceban, Maj Vinberg, Lars Vedel Kessing, Roger C. Ho, Taeho Greg Rhee, Hartej Gill, Bing Cao, Rodrigo B. Mansur, Yena Lee, Joshua Rosenblat, Kayla M. Teopiz, Roger S. McIntyre
Summary: This study assessed the prevalence of type 2 diabetes, impaired fasting glucose, general obesity, and abdominal obesity in patients with bipolar disorder. The findings showed that patients with bipolar disorder had a higher prevalence of these conditions compared to the control group.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Water Resources
Mengzhen Zhao, Dandan Wei, Lulu Wang, Qingqing Xu, Juan Wang, Jiayu Shi, Cuicui Ma, Jintian Geng, Wenqian Huo, Tao Jing, Chongjian Wang, Zhenxing Mao
Summary: This study found that exposure to PYRs is significantly associated with the risk of developing IFG and T2DM in rural Chinese populations. Inflammatory indicators NE and BASO partly mediate the association between PYRs, particularly cyfluthrin, and T2DM.
EXPOSURE AND HEALTH
(2023)
Article
Endocrinology & Metabolism
Guochen Li, Matthew D. Jankowich, Yanqiang Lu, Luying Wu, Liping Shao, Chaofu Ke
Summary: This study investigated the association between baseline preserved ratio impaired spirometry (PRISm) and the risk of developing type 2 diabetes (T2D), as well as the potential role of circulating metabolites in mediating this association. The results showed that individuals with PRISm had a higher likelihood of developing T2D, and several metabolites were found to mediate the relationship between PRISm and T2D.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Manqi Zheng, Shouling Wu, Shuohua Chen, Xiaoyu Zhang, Yingting Zuo, Chao Tong, Haibin Li, Changwei Li, Xinghua Yang, Lijuan Wu, Anxin Wang, Deqiang Zheng
Summary: The aim of this study was to develop and validate sex-specific risk prediction models for predicting 5-year risk of type 2 diabetes (T2D) in individuals with impaired fasting glucose (IFG) using easily obtainable clinical data. The models outperformed existing models and showed well-validated performance in both internal and external validation. A risk scoring system and a web calculator were constructed as practical tools for public use.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Nutrition & Dietetics
Carola Buscemi, Yvelise Ferro, Roberta Pujia, Elisa Mazza, Giada Boragina, Angela Sciacqua, Salvatore Piro, Arturo Pujia, Giorgio Sesti, Silvio Buscemi, Tiziana Montalcini
Summary: This study found that elderly women with low appendicular skeletal muscle mass (ASMM) had a higher likelihood of developing impaired fasting glucose (IFG) and type 2 diabetes (T2D). Women with sarcopenia were also at an increased risk for IFG/T2D, independent of BMI and fat mass. Further research is needed to confirm these findings in men and other age groups.
Article
Cardiac & Cardiovascular Systems
Ayuba Issaka, Adrian J. Cameron, Yin Paradies, Jean B. Kiwallo, William K. Bosu, Yessito Corine N. Houehanou, Chea S. Wesseh, Dismand S. Houinato, Diarra J. P. Nazoum, Christopher Stevenson
Summary: The study found that waist-to-height ratio (WHtR) and waist circumference are the obesity indices most strongly associated with type 2 Diabetes Mellitus (T2DM) and impaired fasting glucose (IFG) among adults from West African countries. Due to its simplicity, waist circumference may be the most useful metric for conveying the risk of T2DM in this population.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
Fariba Ahmadizar, Kan Wang, Elif Aribas, Lana Fani, Alis Heshmatollah, M. Kamran Ikram, Maryam Kavousi
Summary: This study found that impaired fasting glucose (IFG) is associated with a higher risk of cardiovascular disease compared to normal glycemia, especially among overweight and obese individuals. The risk of IFG in men is comparable to that of type 2 diabetes (T2D). Overweight/obesity increases the burden of lifetime cardiovascular disease risk in individuals with IFG.
BMJ OPEN DIABETES RESEARCH & CARE
(2021)
Article
Geriatrics & Gerontology
Rui Song, Xuejiao Chen, Kun He, Xueqi Hu, Kaizhi Bai, Wenlong Shi, Songhe Shi
Summary: This study aimed to explore the association between body mass index (BMI) and mortality in elderly Chinese individuals with different glycemic statuses. The results showed that higher BMI was associated with reduced mortality in individuals with normal fasting glucose (NFG) and type 2 diabetes mellitus (T2DM), but not in individuals with impaired fasting glucose (IFG).
Article
Environmental Sciences
Lili Xiao, Wei Li, Chunmei Zhu, Shijie Yang, Min Zhou, Bin Wang, Xing Wang, Dongming Wang, Jixuan Ma, Yun Zhou, Weihong Chen
Summary: This study found that chronic cadmium exposure may contribute to elevated fasting blood glucose levels and an increased risk of type 2 diabetes mellitus. Increasing levels of cadmium exposure were associated with higher fasting blood glucose changes and incidence of type 2 diabetes mellitus.
ENVIRONMENTAL RESEARCH
(2021)
Article
Endocrinology & Metabolism
Adrian Post, Wendy A. Dam, Sara Sokooti, Dion Groothof, Jolein Gloerich, Alain J. van Gool, Daan Kremer, Ron T. Gansevoort, Jacob van den Born, Ido P. Kema, Casper F. M. Franssen, Robin P. F. Dullaart, Stephan J. L. Bakker
Summary: This study suggests that circulating FGF21 concentration may serve as an early biomarker for the development of type 2 diabetes. Higher levels of FGF21 are independently associated with an increased risk of incident T2D, especially in individuals with low fasting plasma glucose.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Yogesh Yadav, Davide Romeres, Claudio Cobelli, Chiara Dalla Man, Rickey Carter, Ananda Basu, Rita Basu
Summary: This study assessed the diurnal patterns of postprandial glucose tolerance and insulin sensitivity in individuals with and without type 2 diabetes. The results showed differences in glucose and insulin responses at different times of the day between the two groups. These findings not only provide insights into better glycemic control for people with type 2 diabetes, but also improve understanding of daytime glucose metabolism in overweight individuals without impaired glucose tolerance or overt diabetes.