Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism

Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults

(2017) Mark A. Reger et al.   JOURNAL OF ALZHEIMERS DISEASE

Downregulation of hypothalamic insulin receptor expression elicits depressive-like behaviors in rats

(2011) Claudia A. Grillo et al.   BEHAVIOURAL BRAIN RESEARCH

Brain Insulin Controls Adipose Tissue Lipolysis and Lipogenesis

(2011) Thomas Scherer et al.   Cell Metabolism

Unconditioned and conditioned effects of intranasally administered insulin vs placebo in healthy men: a randomised controlled trial

(2011) U. Stockhorst et al.   DIABETOLOGIA

Metabolic syndrome and cognitive decline in French elders: The Three-City Study

(2011) C. Raffaitin et al.   NEUROLOGY

Peripheral insulin-sensitizer drug metformin ameliorates neuronal insulin resistance and Alzheimer’s-like changes

(2011) Amit Gupta et al.   NEUROPHARMACOLOGY

The Insulin-Mediated Modulation of Visually Evoked Magnetic Fields Is Reduced in Obese Subjects

(2011) Martina Guthoff et al.   PLoS One

Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease

(2010) Lisa Mosconi et al.   Annals of the New York Academy of Sciences

Neuroendocrine responses to hypoglycemia

(2010) Nolawit Tesfaye et al.   Annals of the New York Academy of Sciences

Intranasal Insulin Enhances Postprandial Thermogenesis and Lowers Postprandial Serum Insulin Levels in Healthy Men

(2010) C. Benedict et al.   DIABETES

New strategies to improve the intranasal absorption of insulin

(2010) Xiaopin Duan et al.   DRUG DISCOVERY TODAY

Analysis of Insulin Sensitivity in Adipose Tissue of Patients with Primary Aldosteronism

(2010) Riccardo Urbanet et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin receptor signaling in the development of neuronal structure and function

(2010) Shu-Ling Chiu et al.   Neural Development

Insulin and Hippocampus Activation in Response to Images of High-Calorie Food in Normal Weight and Obese Adolescents

(2010) Sandra Wallner-Liebmann et al.   Obesity

Insulin enhances glucose-stimulated insulin secretion in healthy humans

(2010) C. Bouche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hormonal regulation of hippocampal dendritic morphology and synaptic plasticity

(2010) Peter R. Moult et al.   Cell Adhesion & Migration

Synaptic Mechanisms for Plasticity in Neocortex

(2009) Daniel E. Feldman   Annual Review of Neuroscience

Insulin Causes Hyperthermia by Direct Inhibition of Warm-Sensitive Neurons

(2009) M. Sanchez-Alavez et al.   DIABETES

Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons

(2009) H. V. Lin et al.   DIABETES

The role of metabolic derangements and glucocorticoid excess in the aetiology of cognitive impairment in type 2 diabetes. Implications for future therapeutic strategies

(2009) Mark W. J. Strachan et al.   DIABETES OBESITY & METABOLISM

Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders?

(2009) M. Hallschmid et al.   DIABETOLOGIA

Central Insulin Signaling Is Attenuated by Long-Term Insulin Exposure via Insulin Receptor Substrate-1 Serine Phosphorylation, Proteasomal Degradation, and Lysosomal Insulin Receptor Degradation

(2009) Christopher M. Mayer et al.   ENDOCRINOLOGY

The Insulin Effect on Cerebrocortical Theta Activity Is Associated with Serum Concentrations of Saturated Nonesterified Fatty Acids

(2009) Otto Tschritter et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin Modulates Food-Related Activity in the Central Nervous System

(2009) Martina Guthoff et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Insulin Therapy and Type 2 Diabetes: Management of Weight Gain

(2009) Samy I. McFarlane   Journal of Clinical Hypertension

Intranasal delivery of neurotrophic factors BDNF, CNTF, EPO, and NT-4 to the CNS

(2009) Sandra R. Alcalá-Barraza et al.   JOURNAL OF DRUG TARGETING

Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors

(2009) D. R. Marks et al.   JOURNAL OF NEUROSCIENCE

Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

(2009) Shyeilla V. Dhuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Inhaled insulin—Intrapulmonary, intranasal, and other routes of administration: Mechanisms of action

(2009) R.I. Henkin   NUTRITION

Control of energy homeostasis by insulin and leptin: Targeting the arcuate nucleus and beyond

(2009) A. Christine Könner et al.   PHYSIOLOGY & BEHAVIOR

RETRACTED: Intranasal insulin prevents cognitive decline, cerebral atrophy and white matter changes in murine type I diabetic encephalopathy

(2008)   BRAIN

Cognitive Dysfunction and Diabetes Mellitus

(2008) Christopher T. Kodl et al.   ENDOCRINE REVIEWS

Rosiglitazone attenuates the cognitive deficits induced by high fat diet feeding in rats

(2008) Asif R. Pathan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Central Control of Body Weight and Appetite

(2008) Stephen C. Woods et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differential Sensitivity of Men and Women to Anorexigenic and Memory-Improving Effects of Intranasal Insulin

(2008) Christian Benedict et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease

(2008) L. Mosconi et al.   NEUROLOGY

Central obesity and increased risk of dementia more than three decades later

(2008) R. A. Whitmer et al.   NEUROLOGY

Insulin Receptor Signaling Regulates Synapse Number, Dendritic Plasticity, and Circuit Function In Vivo

(2008) Shu-Ling Chiu et al.   NEURON

PPARγ agonists as therapeutics for the treatment of Alzheimer’s disease

(2008) Gary Landreth et al.   Neurotherapeutics

An Obesity-AssociatedFTOGene Variant and Increased Energy Intake in Children

(2008) Joanne E. Cecil et al.   NEW ENGLAND JOURNAL OF MEDICINE

Polymorphisms of theFTOGene Are Associated With Variation in Energy Intake, but not Energy Expenditure

(2008) John R. Speakman et al.   Obesity

Intranasal insulin attenuates the hypothalamic–pituitary–adrenal axis response to psychosocial stress

(2008) Andreas Bohringer et al.   PSYCHONEUROENDOCRINOLOGY