Article
Clinical Neurology
Rachel A. Whitmer, Paola Gilsanz, Charles P. Quesenberry, Andrew J. Karter, Mary E. Lacy
Summary: Severe hypoglycemic and hyperglycemic events in older adults with type 1 diabetes are associated with an increased risk of future dementia. Individuals with both severe hypoglycemia and hyperglycemia have the highest risk compared to those with neither event.
Article
Multidisciplinary Sciences
Agustin Ortal, Aida Rodriguez, Maria Pilar Solis-Hernandez, Miguel de Prado, Veronica Rey, Juan Tornin, Oscar Estupinan, Borja Gallego, Dzohara Murillo, Carmen Huergo, Juan Luis Garcia-Llano, Serafin Costilla, Rene Rodriguez
Summary: The study demonstrates that sniffer dogs can be trained to detect the odor of osteosarcoma, distinguishing between patient cells and healthy cells. This non-invasive screening method has the potential to improve early detection and patient survival rates.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Dominique Grandjean, Capucine Gallet, Clothilde Julien, Riad Sarkis, Quentin Muzzin, Vinciane Roger, Didier Roisse, Nicolas Dirn, Clement Levert, Erwan Breton, Arnaud Galtat, Alexandre Forget, Sebastien Charreaudeau, Fabien Gasmi, Caroline Jean-Baptiste, Sebastien Petitjean, Katia Hamon, Jean-Michel Duquesne, Chantal Coudert, Jean-Pierre Tourtier, Christophe Billy, Jean-Marc Wurtz, Anthony Chauvin, Xavier Eyer, Sabrina Ziani, Laura Prevel, Ilaria Cherubini, Enfel Khelili-Houas, Pierre Hausfater, Philippe Devillier, Loic Desquilbet
Summary: This study confirms previous results that detection dogs could play an important role in mass testing situations, identifying individuals infected with SARS-CoV-2. The sensitivity of the dogs ranged from 87% to 94%, and the specificity ranged from 78% to 92%.
Article
Endocrinology & Metabolism
Fei Gao, Cheng Li, Jiahui Peng, Wei Lu, Wei Zhu, Jian Zhou, Jingyi Lu, Xiaojing Ma
Summary: This study found that serum DKK-1 levels significantly decreased after 12 weeks of hypoglycemic treatment, and Delta DKK-1 levels were negatively correlated with baseline DKK-1 levels. Baseline DKK-1 levels were positively related to total cholesterol and LDL-C, with patients in the lower baseline DKK-1 group showing more favorable cardiometabolic factors in some aspects.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2022)
Article
Medicine, General & Internal
Leon Mutesa, Gashegu Misbah, Eric Remera, Hans Ebbers, Esther Schalke, Patrick Tuyisenge, Reuben Sindayiheba, Clement Igiraneza, Jeanine Uwimana, Diane Mbabazi, Epimaque Kayonga, Michel Twagiramungu, Denyse Mugwaneza, Leandre Ishema, Yvan Butera, Clarisse Musanabaganwa, Edson Rwagasore, Friederike Twele, Sebastian Meller, Albert Tuyishime, Robert Rutayisire, Marilyn Milumbu Murindahabi, Lindsay A. Wilson, Noella Bigirimana, Holger A. Volk, Vedaste Ndahindwa, Benoit Kayijuka, Edward J. Mills, Claude Mambo Muvunyi, Sabin Nsanzimana
Summary: The study found that trained dogs can accurately identify respiratory secretion samples from asymptomatic and symptomatic COVID-19 patients, proving to be timely and cost-effective.
FRONTIERS IN MEDICINE
(2022)
Article
Endocrinology & Metabolism
Victoria Colinet, Philippe A. Lysy
Summary: This study investigated the extent of post-hypoglycemic hyperglycemia and factors influencing its characteristics in pediatric patients with type 1 diabetes. The study found that age, BMI, and glycemic control parameters are associated with the characteristics of post-hypoglycemic hyperglycemia in these patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Endocrinology & Metabolism
Paulina Oboza, Natalia Ogarek, Magdalena Olszanecka-Glinianowicz, Piotr Kocelak
Summary: Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency. Environmental and genetic factors contribute to its development. The incidence of T1D and obesity has been increasing, particularly among young individuals. Research shows that overweight or obesity is prevalent in T1D patients and is associated with various risk factors. The coexistence of T1D and T2D, known as double or hybrid diabetes, increases the risk of complications and reduces life expectancy. This review aims to summarize the relationship between overweight/obesity and T1D.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Bing Yang, Xunyu Wei, Yuxin Luo, Jianquan Kan
Summary: The study shows that treatment with low-sugar fruit juice can significantly improve symptoms associated with type 1 diabetes mellitus in mice, with improvements in body weight, insulin level, insulin-like growth factor-1 level, blood urea nitrogen level, among other indicators.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Endocrinology & Metabolism
Alon Haim, Rotem Shalev Shamy, Dana Ridel, Yisrael Parmet, Neta Loewenthal, Idit Liberty, Shai Tejman-Yarden, Eli Hershkovitz, Avinoam Borowsky
Summary: This study shows that acute hyperglycemia impairs driving performance in young type 1 diabetes patients by reducing hazard perception, decreasing the number of glances, shortening headway distance, and increasing the number of braking events.
DIABETES & METABOLISM
(2021)
Article
Medicine, General & Internal
Teresa Quattrin, Lucy D. Mastrandrea, Lucy S. K. Walker
Summary: Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic beta cells, and individuals with this disease rely on insulin for survival. Despite advancements, the burden of this disease remains high. Research shows that blocking the immune attack on beta cells holds promise in preserving endogenous insulin production.
Article
Endocrinology & Metabolism
Jonatan Bagger, Magnus F. G. Grondahl, Asger Lund, Jens J. Holst, Tina Vilsboll, Filip K. Knop
Summary: The study showed that GLP-1 potentiated the glucagon-suppressive effect of glucose in a dose-dependent manner in healthy individuals and patients with type 2 diabetes. However, patients with type 1 diabetes were insensitive to the glucagonostatic effects of both glucose and GLP-1.
Article
Endocrinology & Metabolism
Lars Cederblad, Gustav Eklund, Amund Vedal, Henrik Hill, Jose Caballero-Corbalan, Jarl Hellman, Niclas Abrahamsson, Inger Wahlstrom-Johnsson, Per-Ola Carlsson, Daniel Espes
Summary: A machine learning (ML) model was trained to accurately identify the root causes of hypoglycemic events using continuous- and flash glucose monitoring (CGM/FGM) data.
Article
Endocrinology & Metabolism
Henrik Hill, Per Klaar, Daniel Espes
Summary: This study reveals that hypoglycemic events are frequent in children and adolescents with T1D, regardless of overall metabolic control. Although patients with an HbA1c =48 mmol/mol had a higher frequency of mild hypoglycemic events, there was no increase in serious hypoglycemic events.
BMJ OPEN DIABETES RESEARCH & CARE
(2023)
Article
Behavioral Sciences
Nicholas J. Rutter, Tiffani J. Howell, Arthur A. Stukas, Jack H. Pascoe, Pauleen C. Bennett
Summary: Volunteer-trained companion dogs can successfully locate target odors in controlled conditions in 12 weeks and retain this skill for at least several months, showing promise for addressing financial limitations and welfare implications associated with professional CDDs.
JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH
(2021)
Article
Endocrinology & Metabolism
Serafin Murillo, Laura Brugnara, Joan-Marc Servitja, Anna Novials
Summary: This study compared the effects of High Intensity Interval Training (HIIT) and traditional moderate Intensity Continuous Training (MICT) on glycemic control and fitness capacity. The results showed that HIIT training improves glycemic stability and reduces the frequency of hypoglycemic episodes.
DIABETES & METABOLISM
(2022)
