Article
Multidisciplinary Sciences
Noori Akhtar-Danesh, Andrea Baumann, Mary Crea-Arsenio, Valentina Antonipillai
Summary: This study investigated the mortality of long-term care residents in Ontario, Canada during the COVID-19 pandemic and estimated the excess mortality associated with a positive COVID-19 test. The results showed a significant increase in mortality among long-term care residents during the pandemic, with variations observed based on geographic region and ownership category.
Article
Gastroenterology & Hepatology
Abdool S. Yasseen, Jeffrey C. Kwong, Jordan J. Feld, Naveed Z. Janjua, Christina Greenaway, Lauren Lapointe-Shaw, Morris Sherman, Tony Mazzulli, Rafal Kustra, Liane MacDonald, Beate Sander, Natasha S. Crowcroft
Summary: This study examined the hepatitis C virus cascades of care among immigrants and long-term residents in Ontario, Canada, showing that immigrants had higher rates of nucleic-acid testing, treatment initiation, and viral clearance compared to long-term residents. The findings provide a population-based benchmark for future studies and evaluation of treatment programs and surveillance activities before the introduction of newer medications.
LIVER INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Bradley Quach, Danial Qureshi, Robert Talarico, Amy T. Hsu, Peter Tanuseputro
Summary: This study compared places of care among recent immigrants and long-standing residents in Canada in the last 90 days of life, finding that recent immigrants were more likely to receive inpatient and intensive care services, while long-standing residents were more likely to spend their last days in long-term care settings.
Article
Geriatrics & Gerontology
Danial Qureshi, Connie Schumacher, Robert Talarico, Julie Lapenskie, Peter Tanuseputro, Mary Scott, Amy Hsu
Summary: Recent immigrants waiting for long-term care tend to be younger, come from lower income neighborhoods, and have fewer comorbidities compared to long-standing residents. Caregivers of immigrants are more likely to be unable to continue providing care and express greater distress, while immigrants also experience longer wait times for placement.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Endocrinology & Metabolism
Isabelle Nel, Lucie Beaudoin, Zouriatou Gouda, Camille Rousseau, Pauline Soulard, Matthieu Rouland, Leo Bertrand, Christian Boitard, Etienne Larger, Agnes Lehuen
Summary: Alterations in MAIT cell frequency, phenotype, and function were more pronounced in adults with long-term type 1 diabetes compared to those with recent-onset diabetes. There were correlations between MAIT cell variables and clinical characteristics. Additionally, the presence of another autoimmune disease in women with long-term type 1 diabetes exacerbated MAIT cell alterations.
Article
Geriatrics & Gerontology
Michelle C. Odden, Sei J. Lee, Michael A. Steinman, Anna D. Rubinsky, Laura Graham, Bocheng Jing, Kathy Fung, Zachary A. Marcum, Carmen A. Peralta
Summary: The study evaluated the incidence of deprescribing antihypertensive medication among older adults in VA nursing homes, finding that 70.4% of residents had at least one deprescribing event during their stay, with 48.7% experiencing a net reduction in antihypertensive medications. Among potentially triggering events, a 50% increase in serum creatinine was associated with the greatest likelihood of deprescribing, while a fall in the past 30 days was associated with the smallest increased risk of deprescribing.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Geriatrics & Gerontology
Shanna C. Trenaman, Maia von Maltzahn, Ingrid Sketris, Hala Tamim, Yan Wang, Samuel A. Stewart
Summary: This study describes the dispensing patterns of antipsychotic medications to LTC residents and examines factors associated with continued use of antipsychotics after a fall-related hospitalization. The study found that 90% of antipsychotic dispensations were given to LTC residents, and 40% of LTC residents received at least one antipsychotic dispensation each year. The results of this study suggest the need to address the issue of antipsychotic dispensation to older adults.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Geriatrics & Gerontology
Tracie C. Harrison, Shelley A. Blozis, Bianca Schmidt, Alisha Johnson, Roxanne Moreno, Sherilyn Mead, Michael Gayle
Summary: This study embedded music and audiobooks in 13 long-term care facilities to compare the effects on agitation in people with ADRD. It found that both music and audiobooks reduced agitation in residents, with music showing initially greater effects.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Review
Chemistry, Analytical
Jiaju Yin, Jiandong Xu, Tian-Ling Ren
Summary: This paper first introduces the basic knowledge and significance of sleep monitoring. Then, it describes the research progress of bioelectrical, biomechanical, and biochemical signals used for sleep monitoring based on the types of physiological signals monitored. Since monitoring sleep quality based on only one signal is not ideal, this paper also reviews the research on multi-signal monitoring and introduces systematic sleep monitoring schemes. Finally, a conclusion and discussion of sleep monitoring are presented to propose potential future directions and prospects for sleep monitoring.
Article
Critical Care Medicine
Anne-Francoise Rousseau, Hallie C. Prescott, Stephen J. Brett, Bjoern Weiss, Elie Azoulay, Jacques Creteur, Nicola Latronico, Catherine L. Hough, Steffen Weber-Carstens, Jean-Louis Vincent, Jean-Charles Preiser
Summary: Survivors of intensive care often suffer from post-intensive care sequelae, collectively known as post-intensive care syndrome (PICS). The impact of PICS on quality of life, health-related costs, and hospital readmissions is a significant public health issue. This Viewpoint summarizes current knowledge and gaps in understanding PICS and its management approaches.
Article
Geriatrics & Gerontology
Harminder Guliani, Thomas Hadjistavropoulos, Shan Jin, Lisa M. Lix
Summary: This study found that LTC residents with clinically significant pain incurred higher direct health care costs compared to those without or with non-daily mild pain. Even after controlling for various factors, this cost difference persisted. Improvements in pain care can potentially reduce costs and enhance quality of life for LTC residents.
Article
Economics
Jean-William Laliberte
Summary: This study estimates the long-term impact of growing up in better neighborhoods and attending better schools on educational attainment. By combining spatial regression-discontinuity design and neighborhood migration studies, the research finds significant effects on educational achievement, with a large portion attributed to access to better schools.
AMERICAN ECONOMIC JOURNAL-ECONOMIC POLICY
(2021)
Article
Environmental Sciences
Naizhuo Zhao, Lauren Pinault, Olaniyan Toyib, Jennifer Vanos, Michael Tjepkema, Sabit Cakmak
Summary: The study found positive associations between long-term exposure to ozone and mortality due to Parkinson's disease, dementia, stroke, and multiple sclerosis.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Petter Bjornstad, Kimberly L. Drews, Sonia Caprio, Rose Gubitosi-Klug, David M. Nathan, Bereket Tesfaldet, Jeanie Tryggestad, Neil H. White, Philip Zeitler
Summary: Youth-onset type 2 diabetes patients are at increasing risk of complications over time, with most developing complications by young adulthood. Complications were more common among participants of minority race and ethnic group and those with hyperglycemia, hypertension, and dyslipidemia.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Nutrition & Dietetics
Karoliina Salminen, Mirjami Willman, Hannu Kautiainen, Kaisu Pitkala, Hanna-Maria Roitto, Merja Suominen
Summary: The study found that while there was no significant difference in energy intake among older long-term care residents between 2007 and 2017-8, fat intake increased while carbohydrate, total protein, and protein intake decreased. Some vitamins and minerals intake decreased, and fat intake relative proportion increased in 2017-8 compared to 2007.
CLINICAL NUTRITION
(2021)