Article
Endocrinology & Metabolism
Milina Tancic-Gajic, Miodrag Vukcevic, Miomira Ivovic, Ljiljana V. Marina, Zorana Arizanovic, Ivan Soldatovic, Milos Stojanovic, Aleksandar Dogo, Aleksandra Kendereski, Svetlana Vujovic
Summary: The study suggests that obstructive sleep apnea is associated with lower total and free testosterone levels in severely obese men. This finding indicates a potential impact of sleep disorders on sex hormone levels.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Orthopedics
Jian-Ming Zhao, Bi-Ying Wang, Jie-Feng Huang, Han-Sheng Xie, Meng-Lan Chen, Gong-Ping Chen
Summary: This study aimed to explore the relationship between bone mineral density (BMD) and obstructive sleep apnea (OSA) in young men. The results showed that moderate OSA patients had higher BMD at the lumbar spine compared to control and severe OSA groups. Further analysis revealed that LaSO2 and BMI were independent explanatory variables for BMD. These findings suggest a link between OSA and bone metabolism in younger men, with moderate OSA-related hypoxia positively affecting BMD. However, more research is needed to fully understand the effects of recurrent hypoxia on bone metabolism.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Pediatrics
Hanna-Leena Kukkola, Turkka Kirjavainen
Summary: The study found that obstructive sleep apnea (OSA) in infants without clear syndromes or structural anomalies is position-dependent and shows improvement in the following months.
PEDIATRIC PULMONOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Sofia Romero-Peralta, Francisco Garcia-Rio, Pilar Resano Barrio, Jose Luis Izquierdo Alonso, Maria Esther Viejo-Ayuso, Rosa Mediano San Andres, Laura Silgado Martinez, Leticia Alvarez Balado, Jorge Castelao Naval, Jesus Fernandez Frances, Olga Mediano
Summary: This study aimed to determine the phenotype of obstructive sleep apnea (OSA) in women. The study found that women with OSA had lower apnea-hypopnea index (AHI) values, desaturation index, and saturation time <90% compared to men. Women also had a higher risk of various symptoms and comorbidities.
JOURNAL OF WOMENS HEALTH
(2022)
Article
Clinical Neurology
Hiwa Mohammadi, Ardalan Aarabi, Mohammad Rezaei, Habibolah Khazaie, Serge Brand
Summary: The study found that individuals with OSAS have significantly lower spindle density in N3 and shorter spindle duration in N2 compared to healthy controls. Furthermore, individuals with mild OSAS showed sleep spindle characteristics more similar to healthy controls, unlike those with moderate and severe OSAS.
FRONTIERS IN NEUROLOGY
(2021)
Article
Otorhinolaryngology
Diogo Raposo, Marco Menezes, Joao Rito, Mafalda Trindade-Soares, Cristina Adonis, Helena Cristina Loureiro, Filipe Freire
Summary: DISE findings varied between surgically naive children and those with persistent obstructive sleep apnea after adenotonsillectomy. Increased obstruction at the tongue base and multilevel obstruction predicted a lower saturation nadir in children with persistent obstructive sleep apnea after adenotonsillectomy.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Article
Clinical Neurology
Jesse L. Parker, Yohannes Adama Melaku, Angela L. D'Rozario, Gary A. Wittert, Sean A. Martin, Peter G. Catcheside, Bastien Lechat, Alison J. Teare, Robert J. Adams, Sarah L. Appleton, Andrew Vakulin
Summary: In this large population-based sample of men, OSA severity measures were independently associated with spindle abnormalities. Further population studies are needed to determine associations between spindle metrics and functional outcomes.
Review
Health Care Sciences & Services
Sy Duong-Quy, Hoang Nguyen-Huu, Dinh Hoang-Chau-Bao, Si Tran-Duc, Lien Nguyen-Thi-Hong, Thai Nguyen-Duy, Tram Tang-Thi-Thao, Chandat Phan, Khue Bui-Diem, Quan Vu-Tran-Thien, Thu Nguyen-Ngoc-Phuong, Vinh Nguyen-Nhu, Huong Le-Thi-Minh, Timothy Craig
Summary: Obstructive Sleep Apnea (OSA) is a common disease that is often underestimated and undertreated in all age groups. Personalized diagnosis and treatment approaches are necessary for clinical practice due to morphological differences, clinical phenotype diversity, and variations in diagnosis and treatment of OSA in children and adults. Treatment should be based on individual tolerance to sleep-quality-related parameters, the harmful effects of hypoxia on the cardiovascular system, and patients' comorbidities.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Nutrition & Dietetics
Silvia Conde, Fatima O. Martins, Sara S. Dias, Paula Pinto, Cristina Barbara, Emilia C. Monteiro
Summary: This study investigated the effect of caffeine consumption on patients with obstructive sleep apnea (OSA) and found that higher caffeine consumption does not alter the variables related to the disease.
Article
Engineering, Biomedical
Xin-Xue Lin, Phone Lin, En-Hau Yeh, Gi-Ren Liu, Wan-Ching Lien, Yuguang Fang
Summary: In this paper, an AI-based framework called RAPIDEST is proposed to detect OSA. The framework only requires EEG signals, simplifying the signal collection process and reducing the complexity of severity determination for apnea and hypopnea.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Medicine, General & Internal
Amalia Ioanna Moula, Iris Parrini, Cecilia Tetta, Fabiana Luca, Gianmarco Parise, Carmelo Massimiliano Rao, Emanuela Mauro, Orlando Parise, Francesco Matteucci, Michele Massimo Gulizia, Mark La Meir, Sandro Gelsomino
Summary: Atrial fibrillation (AF) is the most common arrhythmia, with its incidence increasing with age and comorbidities. Obstructive sleep apnea (OSA) is a chronic sleep disorder more commonly found in older men. Previous studies have shown a link between OSA and AF, although the prevalence of OSA in AF patients remains unknown due to underdiagnosis. This meta-analysis investigated the association between OSA and AF, using data from 54,271 patients. A strong link was found between these two disorders, with the incidence of AF being 88% higher in patients with OSA. Age and hypertension were found to independently strengthen this association, indicating that treating OSA may help reduce AF recurrence. Further research is needed to confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Endocrinology & Metabolism
M. Leentjens, Abdulmohsen Alterki, Mohamed Abu-Farha, P. F. N. Bosschieter, CAL. de Raaff, CEE. de Vries, Eman Al Shawaf, Thangavel Alphonse Thanaraj, Irina Al-Khairi, Preethi Cherian, Arshad Channanath, Sina Kavalakatt, B. A. van Wagensveld, N. de Vries, Jehad Abubaker
Summary: This study found significantly increased levels of ANGPTL7 in both the circulation and adipose tissue of patients with OSA, which were associated with increased inflammation and OSA severity. Bariatric surgery was shown to significantly reduce ANGPTL7 levels and improve OSA.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Medicine, General & Internal
Youmeng Wang, Christoph Schoebel, Thomas Penzel
Summary: Sleep apnea is a common chronic condition that can be classified as obstructive sleep apnea (OSA) or central sleep apnea (CSA). Patients with heart failure often have a combination of OSA and CSA, known as complex sleep apnea syndrome. This review examines different treatment options for OSA in heart failure patients, including surgical and non-surgical approaches, and discusses the potential positive and negative outcomes of these treatments. The review also provides references and suggestions for future research on CSA treatment options.
FRONTIERS IN MEDICINE
(2022)
Article
Clinical Neurology
Vincent Mysliwiec, Matthew S. Brock, Kristi E. Pruiksma, Casey L. Straud, Daniel J. Taylor, Shana Hansen, Shannon N. Foster, Sara Mithani, Sarah Zwetzig, Kelsi Gerwell, Stacey Young-McCaughan, Tyler Powell, John A. Blue Star, Daniel G. Cassidy, Jim Mintz, Alan L. Peterson
Summary: This study aimed to characterize the sleep disorders of insomnia, obstructive sleep apnea (OSA), and comorbid insomnia and OSA (COMISA) in active duty military personnel. The results showed that military personnel with insomnia only and COMISA had more severe symptoms of sleep disorders, sleep-related impairment, fatigue, and psychiatric disorders compared to those with OSA alone. These findings highlight the importance of comprehensive assessment for sleep-related impairment, sleep, and comorbid disorders in military personnel with clinically significant sleep disturbances.
Review
Clinical Neurology
Yi Cai, Hailey M. Juszczak, Emily K. Cope, Andrew N. Goldberg
Summary: Recent evidence suggests a bidirectional relationship between obstructive sleep apnea and microbiota composition, where sleep quality and microbiota alterations influence each other. Animal model studies support the idea that the microbiome mediates disease states associated with obstructive sleep apnea, and potential treatment options include probiotics, prebiotics, and microbiota transplantation.
Article
Endocrinology & Metabolism
Josiane L. Broussard, Florian Chapotot, Varghese Abraham, Andrew Day, Fanny Delebecque, Harry R. Whitmore, Esra Tasali
Article
Endocrinology & Metabolism
Josiane L. Broussard, Jennifer M. Kilkus, Fanny Delebecque, Varghese Abraham, Andrew Day, Harry R. Whitmore, Esra Tasali