Article
Endocrinology & Metabolism
Yanan Huo, Lihong Cheng, Chenxiu Wang, Ying Deng, Ruying Hu, Lixin Shi, Qin Wan, Lulu Chen, Tianshu Zeng, Xuefeng Yu, Xulei Tang, Li Yan, Guijun Qin, Gang Chen, Zhengnan Gao, Guixia Wang, Feixia Shen, Zuojie Luo, Yingfen Qin, Li Chen, Qiang Li, Zhen Ye, Yinfei Zhang, Yufang Bi, Jieli Lu, Mian Li, Min Xu, Yu Xu, Tiange Wang, Zhiyun Zhao, Yuhong Chen, Hongyan Qi, Yuanyue Zhu, Chunyan Hu, Qing Su, Chao Liu, Youmin Wang, Shengli Wu, Tao Yang, Huacong Deng, Jiajun Zhao, Yiming Mu, Guang Ning, Weiqing Wang, Anhua Lin
Summary: Research indicates that nulliparous women or those with multiple births or multiple pregnancy losses are at an increased risk of diabetes in later life, while women who breastfeed for more than 0 to 12 months have a lower risk of diabetes.
JOURNAL OF DIABETES
(2021)
Article
Endocrinology & Metabolism
Anca Balintescu, Marcus Lind, Mikael Andersson Franko, Anders Oldner, Maria Cronhjort, Ann-Marie Svensson, Bjorn Eliasson, Johan Martensson
Summary: In individuals with type 2 diabetes, there is a U-shaped association between HbA(1c) and sepsis, with a fourfold increased risk of death among those developing sepsis.
Article
Endocrinology & Metabolism
Guoying Wang, Jessie P. Buckley, Tami R. Bartell, Xiumei Hong, Colleen Pearson, Xiaobin Wang
Summary: The study aimed to identify a lipidomic signature associated with gestational diabetes mellitus (GDM) in the postpartum period and investigate its role in the progression to type 2 diabetes (T2D). A cohort of 1,409 women who delivered a singleton baby was followed up prospectively, and their lipidome was analyzed using liquid chromatography-tandem mass spectrometry. 33 postpartum lipid species were identified to be associated with GDM, and 4 of them were also associated with incident T2D, mediating the progression from GDM to T2D. Including these lipid species improved the prediction of T2D when considering the entire follow-up period.
Article
Endocrinology & Metabolism
Zhaonan Wang, Jonathan Hazlehurst, Anuradhaa Subramanian, Abd A. Tahrani, Wasim Hanif, Neil Thomas, Pushpa Singh, Jingya Wang, Christopher Sainsbury, Krishnarajah Nirantharakumar, Francesca L. Crowe
Summary: This study aimed to compare the mortality rates of individuals at low, moderate, and high risk of diabetic foot disease (DFD) among newly diagnosed type 2 diabetes patients. The results showed that moderate and high risk of DFD were associated with increased mortality risk compared to low risk. Individuals who declined foot examination or had no record also had a higher mortality risk.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Clemens Wittenbecher, Marta Guasch-Ferre, Danielle E. Haslam, Courtney Dennis, Jun Li, Shilpa N. Bhupathiraju, Chih-Hao Lee, Qibin Qi, Liming Liang, A. Heather Eliassen, Clary Clish, Qi Sun, Frank B. Hu
Summary: This study examined the associations of 10-year plasma metabolite changes with subsequent risk of type 2 diabetes (T2D). The findings suggest that long-term deterioration of amino acid and lipid metabolism is associated with increased T2D risk.
Article
Nutrition & Dietetics
Huishi Toh, James A. Thomson, Peng Jiang
Summary: Through a longitudinal study on Nile rats, we found that maternal intake of a high-fiber diet significantly reduces the risk of diet-induced diabetes in offspring, indicating a potential protective effect of a high-fiber diet that can be transmitted through generations.
Article
Nutrition & Dietetics
Jiaxi Yang, Deirdre K. Tobias, Shanshan Li, Shilpa N. Bhupathiraju, Sylvia H. Ley, Stefanie N. Hinkle, Frank Qian, Zhangling Chen, Yeyi Zhu, Wei Bao, Jorge E. Chavarro, Frank B. Hu, Cuilin Zhang
Summary: The study found that among females with a history of GDM, greater consumption of caffeinated coffee was associated with a lower risk of T2D.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Review
Medicine, General & Internal
Ehtasham Ahmad, Soo Lim, Roberta Lamptey, David R. Webb, Melanie J. Davies
Summary: Type 2 diabetes accounts for nearly 90% of global diabetes cases, with an increasing number of affected individuals, particularly among young people. Early detection and proactive management are crucial for preventing complications and reducing mortality. Technology and precision medicine offer potential improvements to treatment outcomes but face significant barriers.
Article
Nutrition & Dietetics
Elizabeth Walker-Short, Teresa Buckner, Timothy Vigers, Patrick Carry, Lauren A. Vanderlinden, Fran Dong, Randi K. Johnson, Ivana V. Yang, Katerina Kechris, Marian Rewers, Jill M. Norris
Summary: This study examined the relationship between infant diet and DNA methylation in infancy and childhood. The results suggested that infant diet was associated with methylation differences in certain genes, some of which were present at birth while others only appeared in infancy. The study also indicated that factors other than diet may also influence DNA methylation outcomes.
Article
Multidisciplinary Sciences
John T. Walker, Diane C. Saunders, Vivek Rai, Hung-Hsin Chen, Peter Orchard, Chunhua Dai, Yasminye D. Pettway, Alexander L. Hopkirk, Conrad V. Reihsmann, Yicheng Tao, Simin Fan, Shristi Shrestha, Arushi Varshney, Lauren E. Petty, Jordan J. Wright, Christa Ventresca, Samir Agarwala, Radhika Aramandla, Greg Poffenberger, Regina Jenkins, Shaojun Mei, Nathaniel J. Hart, Sharon Phillips, Hakmook Kang, Dale L. Greiner, Leonard D. Shultz, Rita Bottino, Jie Liu, Jennifer E. Below, Stephen C. J. Parker, Alvin C. Powers, Marcela Brissova
Summary: Integration of multiomics data with functional analysis of pancreatic tissues from individuals with early-stage type 2 diabetes indicates that the genetic risk converges on RFX6, which regulates chromatin architecture at multiple risk loci.
Article
Endocrinology & Metabolism
Oscar H. Roa Duenas, Anna C. Van der Burgh, Till Ittermann, Symen Ligthart, M. Arfan Ikram, Robin Peeters, Layal Chaker
Summary: Current evidence suggests an increased risk of type 2 diabetes in individuals with hypothyroidism and lower FT4 levels within the reference range. However, the evidence in this area is still limited and further population-based studies are needed to confirm this association.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Cardiac & Cardiovascular Systems
Juhua Luo, Allison Hodge, Michael Hendryx, Julie E. Byles
Summary: This study found that in middle-aged women, initial BMI, rapid weight increase, early age of obesity onset, and greater obese-years are positively associated with the risk of developing type 2 diabetes mellitus. Therefore, slowing down weight increases, delaying the onset of obesity, or reducing cumulative exposure to obesity may substantially lower the risk of developing type 2 diabetes.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Dario Giugliano, Maria Ida Maiorino, Giuseppe Bellastella, Katherine Esposito
Summary: The commentary discusses the concepts of removed and residual risks in conditioning the cardiorenal outlook of patients with type 2 diabetes. The study highlights the significant role of newer antihyperglycemic drugs, especially SGLT-2i, in reducing cardiovascular events and the progression of diabetic kidney disease.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Nutrition & Dietetics
Andrea Da Porto, Alessandro Cavarape, GianLuca Colussi, Viviana Casarsa, Cristiana Catena, Leonardo A. Sechi
Summary: Polyphenols, with anti-inflammatory and antioxidant properties, are plant-derived compounds associated with the pathogenesis of type 2 diabetes. Dietary patterns rich in polyphenols have favorable effects on glucose metabolism and may help prevent type 2 diabetes.
Article
Biochemistry & Molecular Biology
Ying-Chen Huang, Gerald F. Combs Jr, Tung-Lung Wu, Huawei Zeng, Wen-Hsing Cheng
Summary: Optimal selenium status is important for overall health, and it can be influenced by various factors such as food intake pattern, age, sex, and health status. Insufficient intake of selenium can reduce the expression of selenium-containing proteins, while both insufficient and excessive intakes may increase the risk of type 2 diabetes mellitus. Understanding the relationship between selenium status and diabetes risk can inform the establishment of safe and adequate selenium intake.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2022)
Article
Cardiac & Cardiovascular Systems
Juan C. Quiroz, David Brieger, Louisa R. Jorm, Raymond W. Sy, Michael O. Falster, Blanca Gallego
Summary: In addition to clinical factors, private patients are more likely to receive catheter ablation (CA) and earlier ablation for non-valvular atrial fibrillation (AF) than public patients. Further investigation is needed to explore whether the earlier access to ablation procedures in private patients leads to differences in outcomes among patients with atrial fibrillation.
HEART LUNG AND CIRCULATION
(2022)
Article
Obstetrics & Gynecology
Stephanie K. Y. Choi, Christos Venetis, William Ledger, Alys Havard, Katie Harris, Robert J. Norman, Louisa R. Jorm, Georgina M. Chambers
Summary: In a country with supportive funding for medically assisted reproduction (MAR) technologies, the proportion of MAR births increased from 5.1% in 2009 to 6.7% in 2017, with ART births increasing by 55% and stable contribution from OI/IUI births.
HUMAN REPRODUCTION
(2022)
Review
Critical Care Medicine
Matthew Miller, Duncan Bootland, Louisa Jorm, Blanca Gallego
Summary: Ambulance dispatch algorithms should function as clinical prediction rules to identify high and low acuity patients. However, systematic reviews of dispatch algorithms are rare and often miss the complete value-added evidence chain. This scoping review aimed to summarize the literature on dispatch triage in trauma and identified important gaps in the evidence chain, suggesting the need for standardized outcomes and intelligent dispatch systems.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Letter
Medicine, General & Internal
Lara Harvey, Ian A. Harris, Rebecca J. Mitchell, Adrian Webster, Ian D. Cameron, Louisa Jorm, Hannah Seymour, Pooria Sarrami, Jacqueline Close
MEDICAL JOURNAL OF AUSTRALIA
(2022)
Article
Multidisciplinary Sciences
Juan C. Quiroz, Tim Chard, Zhisheng Sa, Angus Ritchie, Louisa Jorm, Blanca Gallego
Summary: Common data models standardize health datasets, enabling reproducibility and large-scale studies. We propose a metadata-driven ETL framework for mapping data, supporting transparency and reuse by multiple institutions.
Article
Obstetrics & Gynecology
Bronwyn K. Brew, Alison Gibberd, Guy B. Marks, Vanessa E. Murphy, Louisa Jorm, Georgina M. Chambers, Donna Hartz, Sandra Eades, Bridgette McNamara
Summary: The study demonstrates that maternal asthma in Indigenous women is associated with an increased risk of emergency cesarean sections, placental abruption, and threatened preterm labor. These risks may be mitigated by improved management of asthma exacerbations during pregnancy.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Immunology
Bette Liu, Heather Gidding, Sandrine Stepien, Michelle Cretikos, Kristine Macartney
Summary: In a mostly infection-naive but highly vaccinated population in Australia, receiving a third dose of COVID-19 vaccine significantly reduced hospitalizations and deaths from SARS-CoV-2 Omicron infections in individuals aged 40 years and above.
Article
Cardiac & Cardiovascular Systems
Shajedur Rahman Shawon, Michael O. Falster, Benjumin Hsu, Jennifer Yu, Sze-Yuan Ooi, Louisa Jorm
Summary: There has been a significant shift over time from CABG to PCI as the preferred revascularization procedure, with older and sicker patients now undergoing PCI. The mortality rate has decreased for CABG but remained unchanged for PCI.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Surgery
Michael O. Falster, Sarah K. Garland, Louisa R. Jorm, C. Barry Beiles, Anthony J. Freeman, Art Sedrakyan, Oluwadamisola T. Sotade, Ramon L. Varcoe
Summary: This study compares the rates of mortality, rupture, and secondary intervention in patients undergoing endovascular repair of intact abdominal aortic aneurysms using different endograft devices. The results show that the overall long-term safety profiles of major endograft devices are similar. However, there may be differences in rates of secondary intervention, with higher rates observed in patients receiving Medtronic and Gore devices.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Letter
Medicine, General & Internal
Xia Wang, Cheryl Carce, Mark Woodward
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Cardiac & Cardiovascular Systems
Annelies L. Robijn, Kristian B. Filion, Mark Woodward, Benjumin Hsu, Clara K. Chow, Sallie-Anne Pearson, Louisa Jorm, Michael O. Falster, Alys Havard
Summary: This study aimed to compare the effectiveness of postdischarge use of varenicline and prescription nicotine replacement therapy (NRT) patches in preventing recurrent cardiovascular events and mortality, and to explore whether this association differs by sex. The results showed that there was no difference in the risk of recurrent cardiovascular events between varenicline and prescription NRT patches after adjusting for confounding factors using propensity scores. Furthermore, there was no significant difference in treatment effects between males and females.
Editorial Material
Medicine, General & Internal
Karen Canfell, Bette Liu, Emily Banks
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Immunology
Bette Liu, Sandrine Stepien, Jiahui Qian, Heather Gidding, Katrina Nicolopoulos, Janaki Amin, Allen Cheng, Kristine Macartney
Summary: This study compared the effectiveness of different COVID-19 vaccines. The results showed that the BNT162b2 mRNA vaccine had higher effectiveness in preventing primary infections compared to mRNA-1273, ChAdOx-1 nCov-19, and NVX-CoV2373. For booster doses, the BNT162b2 mRNA vaccine also showed good effectiveness.
Article
Health Care Sciences & Services
Bette Liu, Sandrine Stepien, Timothy Dobbins, Heather Gidding, David Henry, Rosemary Korda, Lucas Mills, Sallie-Anne Pearson, Nicole Pratt, Claire M. Vajdic, Jennifer Welsh, Kristine Macartney
Summary: This study examines the effectiveness of COVID-19 vaccines against COVID-19 and all-cause mortality during different periods in 2022 using data from Australia. The findings show that the effectiveness of the vaccines in preventing COVID-19 mortality decreases over time since the last dose, emphasizing the importance of administering booster doses to those at highest risk.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2023)
Article
Public, Environmental & Occupational Health
R. Quentin Grafton, John Parslow, Tom Kompas, Kathryn Glass, Emily Banks
Summary: This study investigated the impact of different levels of social distancing on public health and the economy during a 'second wave' outbreak in Australia and provided recommendations for the management of COVID-19. The results showed that stricter and earlier implementation of social distancing measures, as well as longer duration, led to better public health outcomes and lower economic costs. Early relaxation of suppression measures resulted in worse public health outcomes and higher economic costs.
JOURNAL OF PUBLIC HEALTH-HEIDELBERG
(2023)
