Wolfram Syndrome iPS Cells: The First Human Cell Model of Endoplasmic Reticulum Disease

 -Cell Dysfunction Due to Increased ER Stress in a Stem Cell Model of Wolfram Syndrome

(2013) L. Shang et al.   DIABETES

Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation

(2013) L. L. Bonnycastle et al.   DIABETES

Phenotypic characteristics of early Wolfram syndrome

(2013) Bess A Marshall et al.   Orphanet Journal of Rare Diseases

ER Stress as a Trigger for  -Cell Dysfunction and Autoimmunity in Type 1 Diabetes

(2012) B. O'Sullivan-Murphy et al.   DIABETES

Stimulation of Autophagy Improves Endoplasmic Reticulum Stress-Induced Diabetes

(2012) E. Bachar-Wikstrom et al.   DIABETES

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Wolfram syndrome 1 and adenylyl cyclase 8 interact at the plasma membrane to regulate insulin production and secretion

(2012) Sonya G. Fonseca et al.   NATURE CELL BIOLOGY

Early Brain Vulnerability in Wolfram Syndrome

(2012) Tamara Hershey et al.   PLoS One

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

The binary switch that controls the life and death decisions of ER stressed β cells

(2010) Christine M Oslowski et al.   CURRENT OPINION IN CELL BIOLOGY

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

(2010) Sonya G. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION