Article
Biochemistry & Molecular Biology
Bradly T. Stone, Jian-You Lin, Abuzar Mahmood, Alden J. Sanford, Donald B. Katz
Summary: The gustatory cortex (GC), a crucial structure in consumption decisions, integrates information about taste, experiences, and internal states like illness. This study found that illness is represented in GC activity, which affects taste responses and behavior. Illness causes changes in neural activity, taste response magnitudes, and palatability-relatedness, leading to alterations in consumption.
Article
Behavioral Sciences
Indra R. Bishnoi, Caylen J. Cloutier, Cashmeira-Dove Tyson, Vangel M. Matic, Martin Kavaliers, Klaus -Peter Ossenkopp
Summary: This article reviews the effects of immune activation, primarily via LPS, on learning and memory, including the impact on fear and disgust responses and taste and place-related conditioned disgust memory. The central role of immune activation, particularly pro-inflammatory cytokine activity, in these effects is highlighted.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Dentistry, Oral Surgery & Medicine
J. Zhu, H. Zhang, J. Li, X. Zheng, X. Jia, Q. Xie, L. Zheng, X. Zhou, Y. Wang, X. Xu
Summary: Recent studies suggest that lithium chloride can alleviate radiation-induced oral mucositis and taste dysfunction, promoting restoration of oral mucosa and taste bud function post-irradiation. Activation of Wnt/beta-catenin signaling pathway may represent a promising therapy to improve the quality of life of patients receiving radiotherapy.
JOURNAL OF DENTAL RESEARCH
(2021)
Article
Psychology, Multidisciplinary
Richard J. Stevenson, Supreet Saluja, Trevor I. Case
Summary: The study found that during the Covid-19 pandemic, there was a significant increase in disgust sensitivity, along with greater vulnerability to disease and aversion to germs, as well as an increased focus on hand and food hygiene, but little change in impulsivity.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Fuminori Kawabata, Yuta Yoshida, Yuki Inoue, Yuko Kawabata, Shotaro Nishimura, Shoji Tabata
Summary: The study shows that chickens have a functional fatty acid taste receptor, GPR120, in their oral tissues, but they do not prefer oleic acid solution. Chickens are able to perceive the taste of oleic acid solution, but do not selectively ingest it.
Review
Ecology
Thom van Dooren, Catherine J. Price, Peter B. Banks, Oded Berger-Tal, Matthew Chrulew, Jane Johnson, Gabrielle Lajeunesse, Kate E. Lynch, Clare McArthur, Finn C. G. Parker, Myles Oakey, Benjamin J. Pitcher, Colleen Cassady St Clair, Georgia Ward-Fear, Sam Widin, Bob B. M. Wong, Daniel T. Blumstein
Summary: Conservation behaviour is a growing field that applies insights from animal behaviour study to tackle wildlife conservation and management challenges. It aims to manage specific behaviours of a species to address conservation issues in a less harmful way. However, ethical considerations need to be taken into account when intervening in animal behaviour for conservation purposes. A framework and decision support tool are developed to help managers and researchers evaluate the ethical implications of conservation behaviour interventions compared to other options.
TRENDS IN ECOLOGY & EVOLUTION
(2023)
Article
Biochemistry & Molecular Biology
Hiroki Toyoda, Ayano Katagiri, Takafumi Kato, Hajime Sato
Summary: Intranasal administration of rotenone impairs conditioned taste aversion memory in mice by decreasing GABAergic synaptic transmission and causing LTD impairment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Behavioral Sciences
Huiling Sun, Jinrong Li, Junbao Yan, Bo Sun, Xiaojing Wei, Lin Song, Jianqun Yan
Summary: The absence of dopamine D3 receptors decreases sweet-taste sensitivity and alters the mRNA expression levels of taste-related molecules in mice.
Article
Neurosciences
Daisuke H. Tanaka, Shusheng Li, Shiori Mukae, Tsutomu Tanabe
Summary: The study provides evidence that the TRAP method can induce genetic recombination in quinine-activated neurons in the Central Amygdala. These results suggest that the TRAP method can be used to access specific functional neurons in the CeA.
NEUROSCIENCE LETTERS
(2021)
Article
Psychology, Experimental
Supreet Saluja, Ilona Croy, Anne Gruhl, Alexander Croy, Majid Kanbaty, Andreas Hellmann, Richard J. Stevenson
Summary: Disgust serves as a defense mechanism to protect the body from toxins and disease. This study compared the facial responses to touch, smell, and taste disgusts and found distinct facial expressions and functional goals for each sensory disgust.
Article
Psychology, Social
Kaitlyn P. White, Stanislaw K. Czerwinski, Rachel Mulhearn, Peter K. Jonason
Summary: This study examines people's willingness to adopt different solutions to mating shortages and finds that individual differences in disgust are related to their choices. People's level of sexual disgust affects their willingness to abstain, lower their standards, or travel farther for potential partners.
PERSONALITY AND INDIVIDUAL DIFFERENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Ivonne Cassaigne, Ron Thompson, Richard McKenna, Rodrigo A. Medellin, William Given, Francisco Remolina, Rodrigo Nunez, Diego Woolrich, Fernando Luna
Summary: This study successfully induced conditioned taste aversion in six captive jaguars using Thiabendazole (TBZ), providing an important tool to reduce livestock predation and protect this endangered species.
APPLIED ANIMAL BEHAVIOUR SCIENCE
(2023)
Article
Neurosciences
Agustin Salguero, Leonardo Marengo, Enrique Portillo-Salido, Leandro Ruiz-Leyva, Cruz Miguel Cendan, Ignacio Moron Henche, Ricardo Marcos Pautassi
Summary: The study explored the effects of sigma-1 receptors (S1-R) activation on ethanol-induced conditioned taste aversion (CTA) in early adolescence and terminal adolescence/emerging adulthood in female Wistar rats. The results showed that S1-R activation attenuated the learning of ethanol-induced CTA at terminal adolescence but not at early adolescence. Additionally, S1-R activation did not significantly affect binge-like ethanol intake in terminal adolescents.
NEUROSCIENCE LETTERS
(2022)
Article
Pharmacology & Pharmacy
Samuel Orubu, Richard A. Kendall, Yucheng Sheng, Catherine Tuleu
Summary: This study evaluated the taste-masking ability of milk in drug administration. It was found that milk could mask the taste of zinc sulfate in a mannitol-based formulation but not the taste of paracetamol. Samples without grittiness were more likely to be accepted as medicine.
Article
Biology
Junko Nakai, Kengo Namiki, Kanta Fujimoto, Dai Hatakeyama, Etsuro Ito
Summary: Food deprivation activates FOXO and enhances learning ability in snails. The insulin signaling pathway plays an important role in CTA learning, but the administration of insulin may affect the localization of LymFOXO.
Article
Biochemistry & Molecular Biology
Leandro Ruiz-Leyva, Ana Vazquez-Agredos, Ana M. Jimenez-Garcia, Olga Lopez-Guarnido, Antonio Pla, Ricardo Marcos Pautassi, Ignacio Moron Henche, Cruz Miguel Cendan
Summary: The present study validates a novel model of voluntary ethanol consumption in male Wistar rats, in which ethanol access follows binge eating, and demonstrates a significant increase in ethanol consumption after binge eating compared to control eating. This model shows remarkable potential for research on different stages of alcohol addiction and assessing interactions between alcohol consumption and other addictive-like behaviors.
Article
Substance Abuse
Angelina Pilatti, Yanina Michelini, Adrian J. Bravo, Ricardo Marcos Pautassi
Summary: This study found that distress tolerance is associated with alcohol outcomes in Argentinean college students via coping and enhancement motives. The ability to withstand negative affect could be a focus of interventions to prevent the development of maladaptive patterns of drinking.
SUBSTANCE USE & MISUSE
(2022)
Article
Psychology, Clinical
Angelina Pilatti, Gabriela Rivarola Montejano, Macarena Nillus, Macarena Fernandez, Ricardo Marcos Pautassi
Summary: This study investigated the differences between frequent and sporadic marijuana users among university students in Argentina. The findings revealed distinct variations in consumption backgrounds, motives, perceived norms, and protective strategies, and suggested the usefulness of these variables in distinguishing between the two types of users.
ACTA COLOMBIANA DE PSICOLOGIA
(2022)
Article
Neurosciences
Marcos Brandao Conto, Ricardo Marcos Pautassi, Rosana Camarini
Summary: There is a high co-occurrence between depression and alcohol use disorder. Subanesthetic doses of ketamine have short-acting and long-lasting antidepressant effects. This study investigated the interaction between ketamine-induced antidepressant effects and ethanol's rewarding effects, as well as the effect of ethanol on the antidepressant actions of ketamine. The expression of brain-derived neurotrophic factor (BDNF) and its receptors TrkB and p75NTR in the prefrontal cortex and hippocampus were examined. The findings suggest that ethanol can interfere with the antidepressant effects of ketamine and highlight potential interactions between ethanol and ketamine that may undermine ketamine's putative antidepressant effects.
Article
Neurosciences
Agustin Salguero, Leonardo Marengo, Enrique Portillo-Salido, Leandro Ruiz-Leyva, Cruz Miguel Cendan, Ignacio Moron Henche, Ricardo Marcos Pautassi
Summary: The study explored the effects of sigma-1 receptors (S1-R) activation on ethanol-induced conditioned taste aversion (CTA) in early adolescence and terminal adolescence/emerging adulthood in female Wistar rats. The results showed that S1-R activation attenuated the learning of ethanol-induced CTA at terminal adolescence but not at early adolescence. Additionally, S1-R activation did not significantly affect binge-like ethanol intake in terminal adolescents.
NEUROSCIENCE LETTERS
(2022)
Article
Substance Abuse
Agustin Salguero, Angelina Pilatti, Yanina Michelini, Gabriela Rivarola Montejano, Ricardo Marcos Pautassi
Summary: This study is important in understanding the factors that promote simultaneous alcohol and marijuana use. The study found that sensation seeking is a predictor of simultaneous use, while emotional suppression plays a role in modulating hazardous drug use behaviors.
SUBSTANCE USE & MISUSE
(2022)
Review
Psychology, Clinical
Constanza Caceres-Ayala, Ricardo M. Pautassi, Maria Jose Acuna, Waldo Cerpa, Daniela L. Rebolledo
Summary: Alcohol consumption has negative effects on skeletal muscle function and structure, especially in the case of binge drinking. Men are more affected than women. Alcohol can impair muscle recovery after exercise, potentially through an imbalance between anabolic and catabolic pathways, reduced regeneration, increased inflammation and fibrosis, and deficiencies in energy balance and mitochondrial function.
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
(2022)
Article
Psychology, Clinical
Angelina Pilatti, Neelamberi D. Klein, Laura Mezquita, Adrian J. Bravo, Matthew T. Keough, Ricardo Marcos Pautassi
Summary: Past research has mainly focused on participants at the country level or in a single region. This study examined the indirect associations of cultural orientation with alcohol use and negative consequences, finding that certain drinking motives played a mediating role.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2023)
Article
Neurosciences
M. C. Fabio, I. J. C. Servin-Bernal, A. L. Degano, R. M. Pautassi
Summary: This study found that transient serotonin depletion during gestation in mice affects central serotonin synthesis and reuptake at weaning, and may also influence behavioral outcomes such as compulsive behavior and sensitivity to the anxiolytic effects of alcohol.
PSYCHOPHARMACOLOGY
(2022)
Article
Psychology, Clinical
Macarena Soledad Fernandez, Angelina Pilatti, Ricardo Marcos Pautassi
Summary: Negative emotional states are likely to contribute to the development of food addiction. The association between negative emotional states and food addiction symptoms may be mediated by altered eating behaviors or by eating-to-cope motives. This study found that stress and depression symptoms were indirectly associated with food addiction symptoms through uncontrolled eating and eating-to-cope motives.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2022)
Article
Substance Abuse
Leandro Ruiz Leyva, Agustin Salguero, Miriam Beatriz Virgolini, Veronica Leonor Romero, Leonardo Marengo, Maria Carolina Fabio, Ignacio Moron, Cruz Miguel Cendan, Ricardo Marcos Pautassi
Summary: The study reveals a significant interaction between adolescent ethanol exposure and binge eating behavior in female rats, leading to increased ethanol consumption. This finding provides valuable insights into the underlying mechanisms of alcohol intake and the long-term consequences of binge drinking.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Psychology, Clinical
Victoria O. Chentsova, Adrian J. Bravo, Angelina Pilatti, Ricardo M. Pautassi, Laura Mezquita, Lee Hogarth
Summary: Earlier age of alcohol use initiation has been consistently associated with later problematic alcohol use. It is unclear which aspect of early initiation is key for risk assessment and whether cultural differences exist. This study examined the relationships between Age of First Use (AFU) and Age of Habitual Use (AHU) on alcohol use behaviors across seven countries. Results show that AFU has a stronger association with drinking frequency, while AHU is more strongly associated with AUDIT scores and negative consequences. Country was found to moderate the relationships between age variables and drinking behaviors.
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
(2023)
Review
Psychology, Clinical
Anny Gano, Terrence Deak, Ricardo Marcos Pautassi
Summary: In the past decade, neuroinflammatory processes have been found to play a crucial role in substance use disorders. Initially, it was believed that neuroinflammation resulting from prolonged substance misuse contributed to long-term neuropathological consequences. However, it is now understood that the interactions between neuroinflammatory processes and alcohol and drug intake are reciprocal, leading to a vicious cycle that exacerbates the neuropathological effects of drug misuse.
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
(2023)
Article
Substance Abuse
Angelina P. Pilatti, Marcos M. Cupani, Adrian J. Bravo, Laura C. Mezquita, Jennifer M. Read, Ricardo Pautassi, Adrian J. I. Bravo, Christopher C. Conway, James M. Henson, Lee Hogarth, Manuel Ibanez, Debra R. Kaminer, Matthew Keough, Laura A. Mezquita, Generos P. Ortet, Matthew G. Pearson, Angelina Pilatti, Mark Prince, Jennifer Read, Hendrik Roozen, Paul Ruiz
Summary: The present study aimed to investigate the utility of the B-YAACQ as a screening tool in identifying college students at-risk for problematic alcohol use. The results suggested that the B-YAACQ can effectively distinguish between different risk levels and is highly correlated with other measures of alcohol use.
SUBSTANCE USE & MISUSE
(2023)
Article
Psychology, Developmental
Gabriela Rivarola Montejano, Angelina Pilatti, Ricardo Marcos Pautassi
Summary: This study identified the prospective role of trait-like impulsivity and risk taking in influencing drinking patterns among adolescents in Argentina. Specifically, trait-like impulsivity, particularly Sensation Seeking, and risk-taking behaviors were found to distinguish between different drinking categories and Abstainers, especially in women. These findings highlight the importance of developing sex-specific interventions targeting adolescents with high levels of impulsivity and risk-taking.
REVISTA DE PSICOLOGIA CLINICA CON NINOS Y ADOLESCENTES
(2022)
