Article
Clinical Neurology
Kuan-Ru Chen, Tsung Yu, Yueh-Ju Lien, Yen-Yin Chou, Pao-Lin Kuo
Summary: Maternal diabetes during pregnancy, including T1DM, T2DM, and GDM, is associated with an increased risk of some neurodevelopmental disorders (NDDs) in offspring.
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY
(2023)
Article
Psychiatry
Nicholas Chak Lam Yung, Corine Sau Man Wong, Joe Kwun Nam Chan, Eric Yu Hai Chen, Wing Chung Chang
Summary: Psychotic disorders, including schizophrenia and non-affective psychoses, are linked to premature mortality, with patients experiencing higher rates of all-cause, natural-cause, and unnatural-cause deaths compared to the general population. Respiratory diseases, cardiovascular diseases, and cancers are the primary causes of death in these patient cohorts. Men and women with psychotic disorders have a significantly reduced lifespan, highlighting the urgent need for targeted interventions to improve their physical health.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Medicine, General & Internal
Samicchya Adhikari, Nejla Ghane, Marisa Ascencio, Tiffany Abrego, Kapil Aedma
Summary: Childhood-onset schizophrenia is a rare disorder with symptoms occurring before the age of 13. The complex presentation of the disorder often resembles other childhood disorders. Accurate and timely diagnosis is crucial for treatment outcomes and prognosis.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Psychology, Developmental
Martin John Ellis, Kenneth Larsen, Sophie Seychelle Havighurst
Summary: Childhood Disintegrative Disorder (CDD) is a rare developmental disorder characterized by regression in language and social skills after a period of apparently normal development until at least the age of 2 years. The study found that regression was universal in language and social skills, with onset predominantly at 2-4 years, and was associated with feelings of 'loss' and uncertainty over the prognosis for CDD patients, having profound implications for parental well-being.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Article
Behavioral Sciences
Timothy C. Nielsen, Natasha Nassar, Antonia W. Shand, Hannah F. Jones, Velda X. Han, Shrujna Patel, Adam J. Guastella, Russell C. Dale, Samantha J. Lain
Summary: The aim of this study was to examine the potential synergistic effects between maternal autoimmune disease and early childhood infections and their association with ASD in offspring. The findings showed that both exposures were associated with increased risk of ASD, but there was no evidence of additive interaction between the two exposures.
Article
Psychiatry
Tomoko Nishimura, Takeo Kato, Akemi Okumura, Taeko Harada, Toshiki Iwabuchi, Md. Shafiur Rahman, Tomoya Hirota, Michio Takahashi, Masaki Adachi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nagahide Takahashi, Atsushi Senju, Kenji J. Tsuchiya
Summary: This study investigated trajectory patterns and sex differences in adaptive behaviors in the general population. The results showed that there were differences between males and females in adaptive behaviors, with females scoring higher in the communication domain. In the daily living skills and socialization domains, males and females in the higher adaptive classes had similar trajectories, while in the lower adaptive behavior classes, females scored higher than males. Furthermore, different trajectories were found between females and males, suggesting the need for sex-specific adjustments when standardizing scores for better early detection of skill impairment.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Developmental
Inn-Chi Lee, Yu-Hsun Wang, Jeng-Yuan Chiou, James Cheng-Chung Wei
Summary: This research analyzed the prevalence of autism spectrum disorders in Taiwanese children and its association with perinatal risk factors. The study found significant associations between neonatal jaundice, hypoglycemia, intrauterine growth retardation, craniofacial anomalies, and autism spectrum disorders.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2022)
Article
Pediatrics
Rocio Palomo-Carrion, Rita Pilar Romero-Galisteo, Helena Romay-Barrero, Ines Martinez-Galan, Cristina Lirio-Romero, Elena Pinero-Pinto
Summary: Infantile hemiparesis can have a significant impact on a child's physical and social development, often caused by perinatal stroke, with epilepsy being a common associated disorder. Most infants with hemiparesis are born full-term, and the average age of diagnosis is 8 months.
Article
Biochemistry & Molecular Biology
David Welch, Norman J. Kleiman, Peter C. Arden, Christine L. Kuryla, Manuela Buonanno, Brian Ponnaiya, Xuefeng Wu, David J. Brenner
Summary: This study found no evidence of skin cancer or abnormal skin growths in hairless mice exposed to chronic long-term far-UVC radiation, supporting the long-term safety of far-UVC as an antimicrobial approach to reduce viral and bacterial loads in indoor settings.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Genetics & Heredity
Melisa Durkut, Elisabet Blok, Anna Suleri, Tonya White
Summary: This study explores the bidirectional relationship between autistic traits and brain morphology and finds that the association between autistic traits and brain morphology already exists in childhood and remains relatively stable over time.
Article
Public, Environmental & Occupational Health
Silvia Alemany, Claudia Avella-Garcia, Zeyan Liew, Raquel Garcia-Esteban, Kosuke Inoue, Tim Cadman, Monica Lopez-Vicente, Llucia Gonzalez, Isolina Riano Galan, Ainara Andiarena, Maribel Casas, Katerina Margetaki, Katrine Strandberg-Larsen, Deborah A. Lawlor, Hanan El Marroun, Henning Tiemeier, Carmen Iniguez, Adonina Tardon, Loreto Santa-Marina, Jordi Julvez, Daniela Porta, Leda Chatzi, Jordi Sunyer
Summary: The study found that children prenatally exposed to acetaminophen were more likely to have borderline or clinical ASC and ADHD symptoms in the future. The association was slightly stronger among boys, but postnatal exposure to acetaminophen did not show any significant association with ASC or ADHD symptoms. The results support the need to provide clear information to pregnant women and their partners about the potential risks of acetaminophen use.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Behavioral Sciences
Fan Gao, Chen Chen, Fude Liu, Jianfeng Han
Summary: This study investigated the association between ECG abnormalities and silent vascular brain injury in a stroke-free community-based population. The results showed that left axis deviation was related to the presence of brain infarcts, a long QT interval was associated with severe white matter hyperintensity, and Q and QS waves with ST-T abnormalities were related to sulcal atrophy.
BRAIN AND BEHAVIOR
(2023)
Article
Anesthesiology
Andreas Pikwer, Bei Yang, Malin Granstrom, Niklas Mattsson, Omid Sadr-azodi
Summary: In a population-based cohort study, it was found that exposure to general anesthesia in early childhood is associated with an increased risk of autism or autism spectrum disorder. Further research is needed to determine if anesthesia causes autism or if there are other factors involved.
MINERVA ANESTESIOLOGICA
(2023)
Article
Pediatrics
Holly A. Harris, Ivonne P. M. Derks, Peter Prinzie, Anneke Louwerse, Manon H. J. Hillegers, Pauline W. Jansen
Summary: This study examines the bidirectional association between autism spectrum disorder (ASD) symptoms and eating problems across child development and finds limited evidence for consistent, predictive effects at the individual level. The associations did not differ by child sex.
FRONTIERS IN PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Shengxin Liu, Ralf Kuja-Halkola, Henrik Larsson, Paul Lichtenstein, Jonas F. Ludvigsson, Ann-Marie Svensson, Soffia Gudbjornsdottir, Magnus Tideman, Eva Serlachius, Agnieszka Butwicka
Summary: This Swedish population-based cohort study found that individuals with childhood-onset type 1 diabetes have an increased risk of neurodevelopmental disorders compared to the general population, especially those with poor glycaemic control. Routine neurodevelopmental follow-up visits should be considered in type 1 diabetes, especially in patients with poor glycaemic control.
