Article
Medicine, General & Internal
Jacqueline F. Gould, Maria Makrides, Robert A. Gibson, Thomas R. Sullivan, Andrew J. McPhee, Peter J. Anderson, Karen P. Best, Mary Sharp, Jeanie L. Y. Cheong, Gillian F. Opie, Javeed Travadi, Jana M. Bednarz, Peter G. Davis, Karen Simmer, Lex W. Doyle, Carmel T. Collins
Summary: Limited research suggests that DHA supplementation in infants born before 29 weeks of gestation may have a positive impact on cognitive development.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Pediatrics
Michele Arigliani, Chiara Stocco, Elena Valentini, Carlo De Pieri, Luigi Castriotta, Maria Elena Ferrari, Cristina Canciani, Lorenza Driul, Maria Orsaria, Luigi Cattarossi, Paola Cogo
Summary: The impact of intrauterine growth restriction (IUGR) on lung function in very preterm children mainly affects conducting airways function, with part of the effect being mediated by bronchopulmonary dysplasia. Ventilation inhomogeneity and diffusing capacity are not significantly affected by IUGR.
PEDIATRIC RESEARCH
(2021)
Article
Medicine, General & Internal
Frank H. Bloomfield, Yannan Jiang, Jane E. Harding, Caroline A. Crowther, Barbara E. Cormack
Summary: This study found that giving extra parenteral amino acids at a dose of 1 g per day for 5 days after birth did not increase the number of infants with extremely low birth weight who survived without neurodisability at 2 years.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Pediatrics
Hylke H. Salverda, N. Nathalie J. Oldenburger, Monique Rijken, R. Ratna N. G. B. Tan, Arjan B. te Pas, Jeanine M. M. van Klink
Summary: This cohort study evaluated the neurodevelopmental outcomes at 2 years of age for preterm infants before and after the implementation of automated oxygen control (AOC) as standard care. The study found no statistically significant difference in neurodevelopmental outcomes between the two groups. However, the post-AOC group had fewer parent-reported readmissions during follow-up.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
Min Sheng, Ting Guo, Connor Mabbott, Vann Chau, Anne Synnes, Linda S. de Vries, Ruth E. Grunau, Steven P. Miller
Summary: This study evaluated the relationship between ventricular volume and neurodevelopmental outcomes in children born very preterm. The results showed that ventricular size at birth was associated with cognitive and motor outcomes at 4.5 years, suggesting abnormal white matter maturation in the setting of enlarged ventricular size.
JOURNAL OF PEDIATRICS
(2022)
Article
Neurosciences
Alex M. Pagnozzi, Liza van Eijk, Kerstin Pannek, Roslyn N. Boyd, Susmita Saha, Joanne George, Samudragupta Bora, DanaKai Bradford, Michael Fahey, Michael Ditchfield, Atul Malhotra, Helen Liley, Paul B. Colditz, Stephen Rose, Jurgen Fripp
Summary: Infants born very preterm face neurodevelopmental challenges and early identification through clinical assessment and MRI can enable targeted interventions. This study used a prospective cohort of preterm infants and identified early MRI biomarkers for neurodevelopmental outcomes using advanced imaging techniques. The results demonstrated the utility of MRI prior to term equivalent age for predicting outcomes and initiating early interventions.
Article
Pediatrics
Corine Alberge, Virginie Ehlinger, Nathalie Noack, Catherine Bolzoni, Bruno Colombie, Sophie Breinig, Odile Dicky, Malika Delobel, Catherine Arnaud
Summary: The study aimed to assess the efficacy of post-hospital psychomotor therapy on the development of very preterm infants at nine and 24 months. The results showed that the benefits of psychomotor therapy were not long-lasting.
Article
Pediatrics
Dustin D. Flannery, Erika M. Edwards, Sarah A. Coggins, Jeffrey D. Horbar, Karen M. Puopolo
Summary: This study examines the epidemiology, microbiology, and outcomes of late-onset sepsis among very preterm infants in the United States. The findings reveal a significant proportion of infants suffering from late-onset sepsis, particularly those born at the lowest gestational ages. Infected infants have higher mortality rates and survivors are at increased risk of technology-dependent chronic morbidities.
Article
Pediatrics
Dustin D. Flannery, Erika M. Edwards, Karen M. Puopolo, Jeffrey D. Horbar
Summary: This study investigated the epidemiology and microbiology of early-onset sepsis (EOS) among very preterm infants from 2018 to 2019. The findings revealed an incidence rate of 13.5 per 1000 very preterm births, with Escherichia coli and group B Streptococcus being the most common pathogens. Infected infants had longer hospital stays and lower survival rates, emphasizing the need for novel preventive strategies.
Article
Pediatrics
Carmen Landry, Jon Dorling, Ketan Kulkarni, Marsha Campbell-Yeo, Lisa Morrison, Joyce Ledwidge, Michael Vincer, Satvinder Ghotra
Summary: This study aimed to determine postdischarge iron status and associated factors in very preterm infants. The study found that despite early iron prophylaxis, 32% of infants had iron deficiency. Gestational hypertension in the mother and shorter gestational age were found to be associated with iron deficiency.
JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Sahar Salavati, Arend F. Bos, Lex W. Doyle, Peter J. Anderson, Alicia J. Spittle
Summary: The early motor repertoire of infants born very preterm is strongly associated with improved cognitive and motor performance at 8 years of age.
Article
Pediatrics
Laura Li Ching Ng, Sharina Patel, Hugues Plourde, Marie-Eve Besner, Anie Lapointe, Victoria Bizgu, Guilherme Sant'Anna, Marc Beltempo
Summary: An increase in BMI z score from birth to 36 weeks gestation is associated with higher odds of bronchopulmonary dysplasia (BPD) among preterm infants. Despite similar caloric intake, infants with BPD have a higher weight-for-age but lower length-for-age, resulting in a higher BMI score compared to BPD-free infants.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Li Wang, Li-li Zhao, Jia-ju Xu, Yong-hui Yu, Zhong-liang Li, Feng-juan Zhang, Hui-min Wen, Hai-huan Wu, Li-ping Deng, Hui-yu Yang, Li Li, Lan-lan Ding, Xiao-kang Wang, Cheng-yuan Zhang, Hui Wang
Summary: This multicenter case-control study aimed to analyze the perinatal risk factors and morbidity of pulmonary hemorrhage (PH) among very preterm infants. The results showed that CPAP failure was significantly associated with PH, and PH increased the risk of death and bronchopulmonary dysplasia.
FRONTIERS IN PEDIATRICS
(2022)
Article
Neurosciences
Julia E. Kline, Weihong Yuan, Karen Harpster, Mekibib Altaye, Nehal A. Parikh
Summary: This study examined the relationship between brain network changes in very preterm infants and early cerebral palsy development, finding that brain network efficiency metrics at term may serve as sensitive biomarkers for early CP detection. By identifying decreased brain network segregation in various nodes, including motor regions commonly linked to CP and novel regions, these advanced MRI biomarkers may help in identifying high-risk infants and facilitating early interventions based on early pathophysiological changes.
Article
Pediatrics
Xuefei Zhang, Kaiju Luo, Xiaori He, Pingyang Chen
Summary: This study aimed to assess the association between serum 25-hydroxyvitamin D levels at birth and pulmonary disease morbidities in very preterm infants. The results showed a significant relationship between low serum 25-hydroxyvitamin D levels and the incidence of neonatal respiratory distress syndrome (RDS). However, further research is needed to confirm this association.
PEDIATRIC PULMONOLOGY
(2021)