Odanacatib increases mineralized callus during fracture healing in a rabbit ulnar osteotomy model

Increased fracture callus mineralization and strength in cathepsin K knockout mice

(2014) Michael A. Gentile et al.   BONE

Inhibition of bone resorption by the cathepsin K inhibitor odanacatib is fully reversible

(2014) Y. Zhuo et al.   BONE

Delayed union and nonunions: Epidemiology, clinical issues, and financial aspects

(2014) David J. Hak et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Cathepsin K inhibitors increase distal femoral bone mineral density in rapidly growing rabbits

(2013) Brenda L Pennypacker et al.   BMC MUSCULOSKELETAL DISORDERS

Effects of pharmacological inhibition of cathepsin K on fracture repair in mice

(2013) Do Y. Soung et al.   BONE

The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking

(2011) P. Leung et al.   BONE

Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys

(2011) Patricia J Masarachia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo

(2010) David E. Hughes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cathepsin K inhibitors prevent bone loss in estrogen-deficient rabbits

(2010) Brenda L Pennypacker et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect

(2010) John A Eisman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

(2008) Jacques Yves Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling

(2008) Michelle M. McDonald et al.   BONE

Comparison of Effects of the Bisphosphonate Alendronate Versus the RANKL Inhibitor Denosumab on Murine Fracture Healing

(2008) Louis C Gerstenfeld et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bone remodeling during fracture repair: The cellular picture

(2008) Aaron Schindeler et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY